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Formulas

Pyrimethamine 50 mg/Leucovorin 10 mg Capsules

Bayview Pharmacy's Pyrimethamine 50 mg/Leucovorin 10 mg Capsules are solid dosage forms composed of two shells that enclose the medication. These capsules are designed for easy swallowing and provide a precise dosage of the active ingredients. They are used to treat conditions such as toxoplasmosis, pneumocystis pneumonia, malaria, cryptosporidiosis, and isosporiasis.

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Formula Information

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Bayview Pharmacy is pleased to present a compounded formulation of Pyrimethamine 50 mg/Leucovorin 10 mg Capsules. This formulation is a solid dosage form composed of two gelatin or vegetarian shells that enclose the medication. This design allows for easy swallowing and ensures a precise dosage of the active ingredients, Pyrimethamine and Leucovorin.

Pyrimethamine is an antiparasitic medication that functions by inhibiting the growth of certain parasites. Leucovorin, on the other hand, is a form of folic acid that aids in restoring normal levels of folate in the body. Together, these two active ingredients make this formulation an effective treatment for a variety of disease states.

This formulation is particularly effective in treating toxoplasmosis, a parasitic infection that can lead to serious health complications in individuals with weakened immune systems. It is also used in the treatment of malaria, a mosquito-borne disease characterized by symptoms such as fever and chills. Additionally, this formulation is beneficial for individuals suffering from folic acid deficiency, a condition where the body lacks sufficient amounts of this essential nutrient.

When used as directed, this formulation is both safe and effective. It is crucial that patients adhere to the dosage prescribed by their healthcare provider and avoid exceeding the recommended dosage. Potential side effects to be aware of include nausea, vomiting, and diarrhea.

If you have any queries regarding this formulation or its application in treating the aforementioned disease states, please do not hesitate to contact us at Bayview Pharmacy. We are committed to assisting you in finding the most suitable treatment option for your specific needs.

Drug Interactions

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This compounded formulation of Pyrimethamine 50 mg/Leucovorin 10 mg Capsules is designed for the treatment of toxoplasmosis, malaria, and other protozoal infections. The medication is enclosed within two gelatin or vegetarian shells, ensuring a precise dosage of the active ingredients and facilitating easy swallowing.

It is crucial to note that this formulation is contraindicated in patients with a known hypersensitivity to either pyrimethamine or leucovorin. It is also not recommended for use in patients with severe renal impairment or in pregnant women due to potential risks.

Patients using this formulation should be closely monitored for signs of bone marrow suppression, which may manifest as anemia, leukopenia, and thrombocytopenia. Additionally, signs of peripheral neuropathy, such as numbness, tingling, and pain in the extremities, should be closely observed.

Interactions may occur with other medications, including antacids, phenytoin, and trimethoprim. Therefore, it is essential for patients to inform their healthcare provider of all medications they are currently taking prior to starting this formulation.

If you have any questions or concerns about this formulation, please do not hesitate to reach out for further information and guidance.

How Does it Work

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Pyrimethamine 50 mg/Leucovorin 10 mg Capsules are a compounded formulation used in the treatment of various diseases such as toxoplasmosis, malaria, and AIDS-related infections. The medication is enclosed in two gelatin or vegetarian shells, making it easy to swallow and ensuring a precise dosage of the active ingredients.

Pyrimethamine is an antiparasitic medication that functions by inhibiting the growth of certain parasites. On the other hand, Leucovorin is a form of folic acid that aids in reducing the toxic effects of pyrimethamine. The combination of these two medications effectively treats the underlying infection.

When taking Pyrimethamine 50 mg/Leucovorin 10 mg Capsules, it is crucial to adhere to the instructions provided by your healthcare provider. The dosage and frequency of administration are determined by the severity of the infection and the patient's response to treatment. It is essential to take the medication exactly as prescribed, without skipping doses. To minimize the risk of side effects, it is recommended to take the medication with food.

Common side effects of Pyrimethamine 50 mg/Leucovorin 10 mg Capsules may include nausea, vomiting, diarrhea, and abdominal pain. If you experience any of these side effects, it is important to contact your healthcare provider immediately. Other serious side effects may include rash, fever, chills, and difficulty breathing.

If you have any questions or concerns about Pyrimethamine 50 mg/Leucovorin 10 mg Capsules, please do not hesitate to reach out to your healthcare provider or pharmacist. They can provide you with comprehensive information about how this medication works and how to use it safely and effectively.

Other Uses

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This compounded formulation of Pyrimethamine 50 mg/Leucovorin 10 mg Capsules is a versatile medication that can be used to treat a variety of conditions. It is primarily used in the treatment of toxoplasmic encephalitis, congenital toxoplasmosis, and other protozoal infections. It can also be used as a preventative measure against malaria in certain individuals. The inclusion of leucovorin, a form of folic acid, allows this medication to be used in the treatment of folate deficiency anemia.

Patients should be aware that this medication may cause side effects such as nausea, vomiting, headache, and rash. It is crucial to take this medication as prescribed by a healthcare provider and not to discontinue its use without prior consultation. This medication may interact with other medications, including antacids, antibiotics, and anticonvulsants, so it is important to inform your healthcare provider of any other medications you are currently taking.

Prescribers should note that this formulation is contraindicated in patients with a known hypersensitivity to pyrimethamine or leucovorin. It should also not be used in patients with severe renal impairment or in pregnant women due to potential risks.

If you have any questions or concerns about the use of this formulation, please do not hesitate to contact us at Bayview Pharmacy. We are here to assist you with your medication needs.

Frequently Asked Questions

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What is the Pyrimethamine 50 mg/Leucovorin 10 mg capsule?

This is a compounded formulation of two active ingredients, Pyrimethamine and Leucovorin, enclosed in a solid dosage form. It is designed for easy swallowing and precise dosage.

What are the active ingredients in this capsule?

The active ingredients in this capsule are Pyrimethamine (50 mg) and Leucovorin (10 mg).

What is the purpose of the gelatin or vegetarian shells?

The shells enclose the medication, making it easier to swallow. They also help to provide a precise dosage of the active ingredients.

How should I take this medication?

You should swallow the capsule whole with a glass of water. Do not chew or crush the capsule as this can affect the release of the medication.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses at the same time.

What are the potential side effects of this medication?

Like all medications, Pyrimethamine/Leucovorin can cause side effects. These may include nausea, vomiting, and loss of appetite. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I take this medication if I am pregnant or breastfeeding?

Before taking this medication, inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will be able to advise you on the best course of action.

Can I take this medication with other medicines?

Before starting any new medication, including Pyrimethamine/Leucovorin, inform your healthcare provider about all the medicines you are currently taking. This includes prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I do if I overdose on this medication?

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose may include severe nausea, vomiting, or stomach pain.

How should I store this medication?

Store this medication at room temperature, away from heat, light, and moisture. Keep it out of the reach of children and pets.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.