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Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment

The Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment is a semi-solid formulation designed for external application to the skin. This ointment is dispensed in a tube and provides a greasy or oily base, which facilitates the localized delivery of the active ingredients. Phenylephrine HCl acts as a vasoconstrictor, reducing swelling and inflammation, while Zinc Oxide serves as a skin protectant with mild astringent and antiseptic properties.

This combination ointment is primarily used for the treatment of anal fissures and hemorrhoids, where the Phenylephrine HCl reduces swelling of the affected area, and the Zinc Oxide promotes barrier protection and healing. Additionally, it may be used in other skin conditions where the reduction of inflammation and skin protection is beneficial.

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Phenylephrine Hydrochloride
Zinc Oxide
Topical Ointment
65cf818b2dcec15cd135c726
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Formula Information

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Our Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment is a carefully crafted semi-solid formulation that is dispensed in a tube for ease of application. This ointment is specifically designed for external use on the skin, where its greasy or oily base not only facilitates the smooth application but also enhances the delivery and absorption of the active ingredients into the affected area. The combination of Phenylephrine HCl and Zinc Oxide in this ointment is strategically chosen for its therapeutic benefits in treating a variety of skin conditions.

Phenylephrine HCl is a vasoconstrictor that works by narrowing the small blood vessels in the skin. This action can help reduce redness and swelling, providing relief from discomfort associated with skin inflammation. It is particularly useful in conditions where the reduction of blood flow to the area can lead to an alleviation of symptoms. On the other hand, Zinc Oxide is a well-known skin protectant with astringent, antiseptic, and anti-inflammatory properties. It forms a protective barrier on the skin, which not only shields the area from irritants and moisture but also promotes a conducive environment for the healing of minor skin irritations, abrasions, and wounds. The astringent effect of Zinc Oxide can help in the management of weeping or oozing associated with minor skin conditions.

The dual action of Phenylephrine HCl and Zinc Oxide in this ointment makes it an excellent choice for localized treatment of skin issues such as hemorrhoids, anal fissures, and minor skin infections. It can also be beneficial in the management of eczema, diaper rash, and other forms of dermatitis where inflammation and skin barrier protection are needed. The ointment's formulation is designed to be gentle yet effective, providing symptomatic relief while supporting the skin's natural healing process.

For optimal results, the ointment should be applied to the affected area as directed by a healthcare professional. It is important to follow the prescribed dosage and application frequency to ensure safety and efficacy. Patients should be advised to clean and dry the affected area before applying the ointment to prevent any potential infection and to ensure proper adherence of the medication to the skin.

As compounding pharmacists at Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the specific needs of our patients. We encourage both patients and prescribers to reach out to us with any questions or concerns regarding the use of this Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment or any other compounded formulations. Our team is here to support and guide you through the treatment process with expert advice and personalized care.

Drug Interactions

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The Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment is a specialized formulation intended for external use on the skin. Phenylephrine is a vasoconstrictor, which means it narrows the blood vessels in the area where it is applied. This can reduce swelling and inflammation. Zinc oxide is a skin protectant with astringent, soothing, and protective properties. It is commonly used to treat and prevent skin irritations such as minor burns, cuts, and diaper rash. Together, these ingredients can help in managing skin inflammation and promoting wound healing.

When considering drug interactions, it is important to note that the systemic absorption of phenylephrine and zinc oxide from a topical ointment is generally low. However, patients should be cautious if they are taking medications that could potentially interact with phenylephrine. These include monoamine oxidase inhibitors (MAOIs), which can increase the risk of hypertension when combined with phenylephrine, and beta-blockers or other antihypertensive drugs, which could have their effects altered. Additionally, the use of other topical medications on the same area of skin should be done with caution to avoid potential interactions or skin irritation.

Patients should inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs, herbal supplements, and other topical treatments, to ensure there are no potential interactions with the Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment. It is also advisable to avoid applying other topical preparations to the same area concurrently without medical advice, as this could alter the effects of the ointment or lead to increased risk of side effects.

For any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy. We are here to provide guidance and support to ensure the safe and effective use of this medication.

How Does it Work

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The Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment is a specialized medication designed for the treatment of various skin conditions. This semi-solid formulation is dispensed in a tube and is intended for external application to the skin. The ointment base provides a greasy or oily medium which facilitates the delivery of the active ingredients directly to the affected area, ensuring localized treatment and minimizing systemic absorption.

Phenylephrine HCl is a vasoconstrictor, which means it works by constricting blood vessels in the area where it is applied. This action helps to reduce swelling and inflammation by decreasing blood flow to the site. This can be particularly beneficial in conditions where tissue inflammation is a primary concern, such as in hemorrhoids or certain types of dermatitis. By reducing the caliber of the local blood vessels, phenylephrine can alleviate symptoms like swelling, redness, and discomfort.

Zinc Oxide, on the other hand, serves multiple purposes in this formulation. It is known for its skin-protective properties, acting as a physical barrier on the skin to shield it from irritants and moisture. This is especially useful in conditions like diaper rash or weeping skin lesions, where protection from further irritation is necessary for healing. Additionally, Zinc Oxide has mild astringent properties, which means it can help to dry out oozing areas and reduce excess moisture. It also possesses some antiseptic qualities, which can help to prevent infection in minor skin wounds or abrasions.

Together, these two active ingredients provide a comprehensive approach to treating skin conditions that require both the reduction of inflammation and protection of the skin. The Phenylephrine HCl reduces blood flow to the area to decrease swelling, while the Zinc Oxide forms a protective barrier and aids in the healing process. This combination can be particularly effective for conditions such as skin inflammation, infections, or wound healing, where both symptomatic relief and physical protection are needed.

It is important for patients and prescribers to understand that while this ointment is designed for localized treatment, it should be used with caution in certain populations, such as those with cardiovascular conditions, due to the vasoconstrictive action of phenylephrine. Additionally, the ointment should be applied as directed, typically to clean, dry skin, and in the amount prescribed to avoid potential side effects or overmedication.

If you have any questions about this formulation or its appropriate use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and guidance you need to ensure safe and effective treatment for your patients or yourself.

Other Uses

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Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment is a semi-solid formulation that has been crafted for external application on the skin. Apart from its primary uses in managing skin inflammation, infections, or aiding in wound healing, this unique combination ointment may have a variety of other important therapeutic applications worth considering.

Phenylephrine is primarily known as a vasoconstrictor, which means it narrows blood vessels. When applied topically, this action can help reduce swelling and erythema (redness) associated with hemorrhoids or anal fissures. Thus, this ointment could be an effective option for patients with these anorectal disorders seeking symptomatic relief. Moreover, the vasoconstrictive properties of Phenylephrine might also be beneficial in conditions characterized by superficial vasodilation, such as rosacea, although care should be taken as the skin in these areas is often sensitive.

Zinc oxide, on the other hand, provides a protective barrier on the skin and has mild astringent properties that can help with skin irritation. It is commonly used in diaper rash ointments and for the protective treatment of slightly chapped or irritated skin. The combination with Phenylephrine may enhance the protective barrier function while also reducing inflammation, potentially extending its use to dermatoses where inflammation and skin barrier dysfunction coexist.

In addition to these uses, the formulation could potentially be explored as a supportive treatment in cases of minor skin injuries like scrapes or shallow cuts, due to its protective qualities and potential to reduce inflammation. It's important to note, however, that due to Phenylephrine’s vasoconstrictive properties, the ointment should be used with caution on any skin areas with compromised circulation.

Patients and prescribers should be aware of the potential for allergic reactions or contact dermatitis with any topical application and should test the product on a small area before widespread use. It is also important to consider the duration of use and area of application with products containing vasoconstrictors to avoid potential systemic absorption and resultant side effects.

While we have provided a general overview of potential uses, it is vital for prescribers to evaluate the patients’ individual needs and medical history before recommending this ointment. For situations that fall outside typical use cases, or if there are any questions regarding the formulation’s suitability for a particular patient or condition, we encourage healthcare providers to reach out to us at Bayview Pharmacy for tailored advice and information.

Frequently Asked Questions

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What conditions is this Phenylephrine HCl 0.02%/Zinc Oxide 5% Topical Ointment used for?

This compounded formulation is typically used to treat skin conditions that may involve inflammation, certain skin infections, or to promote wound healing. The combination of Phenylephrine HCl and Zinc Oxide can provide symptomatic relief and support the healing process.

How should I apply the ointment?

To apply the ointment, clean and dry the affected area first. Then gently apply a thin layer of the ointment to the skin. It is typically applied two to three times a day or as directed by a healthcare provider.

Can this ointment be used on open wounds?

It is important to consult with a healthcare professional before applying this ointment to open wounds. Depending on the nature of the wound and overall health, a healthcare provider will determine if this ointment is suitable for your specific situation.

What are the side effects of using this topical ointment?

Potential side effects may include skin irritation, redness, or itching at the site of application. If you experience any severe reactions or signs of an allergic reaction, such as hives or difficulty breathing, seek immediate medical attention.

Will this ointment stain my clothes or bedding?

Because the ointment has a greasy or oily base, it can stain fabric. It is advisable to cover the treated area with a bandage or wear protective clothing to prevent the ointment from coming into contact with your clothes or bedding.

How long should I use this ointment?

The duration of use should be based on the advice of your healthcare provider. It's not recommended to use it for longer than prescribed, even if symptoms improve before the medication is finished.

Can I use this ointment with other topical medications?

It is best to consult with a healthcare provider before combining this ointment with other topical medications. There may be interactions that could affect the efficacy of the treatments or increase the risk of side effects.

Should I store this ointment in the refrigerator?

No, you do not need to refrigerate this ointment. It should be stored at room temperature away from moisture and heat. Keep the tube tightly closed when not in use.

Is this compounded ointment safe for children?

The safety and effectiveness of this ointment in children have not been established. Use in pediatric patients should be under the guidance and supervision of a healthcare provider.

Can I use this ointment if I am pregnant or breastfeeding?

Before using this ointment during pregnancy or while breastfeeding, consult with your healthcare provider. They will assess the benefits against any potential risks to the mother and the child.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.