Our custom-compounded Metronidazole 1%/Niacinamide 3%/Panthenol 1%/Tretinoin 0.025% Topical Gel is a meticulously designed formulation that combines the therapeutic benefits of four active ingredients to address a variety of dermatological conditions. This semisolid preparation is uniquely dispensed through a pump mechanism, which ensures ease of use, hygiene, and precise dosing for the patient. The gel base provides a suitable medium for the active ingredients to be applied smoothly on the skin, allowing for targeted treatment and effective absorption.

Metronidazole, an antibiotic and antiprotozoal, is effective in treating inflammatory lesions of rosacea and certain acne conditions. It reduces inflammation and erythema, providing relief from skin discomfort. Niacinamide, a form of vitamin B3, has anti-inflammatory properties that can help improve the appearance of the skin, reduce hyperpigmentation, and enhance the skin's barrier function. It is also known for its ability to treat acne by reducing sebum production and the occurrence of pimples.

Panthenol, also known as pro-vitamin B5, acts as a moisturizer, promoting skin hydration, healing, and softening. It aids in improving skin elasticity and soothing irritated skin. Tretinoin, a derivative of vitamin A, is a powerful agent that promotes skin cell turnover. It is widely recognized for its ability to treat acne, reduce the appearance of fine lines, and improve skin texture and pigmentation issues. The combination of these ingredients in our topical gel formulation provides a multifaceted approach to skin therapy, targeting a range of skin concerns from acne and rosacea to signs of aging and skin barrier repair.

It is important for both patients and prescribers to understand that this formulation should be used as directed, and it is essential to adhere to the prescribed regimen to achieve the best therapeutic outcomes. Patients should be advised on the potential for skin irritation and the importance of using sunscreen due to the photosensitivity risk associated with tretinoin. As with any compounded medication, this formulation is prepared specifically for individual patients based on a healthcare provider's prescription, ensuring that it meets the unique needs of each patient.

If you have any questions or require further information about this custom-compounded topical gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is dedicated to providing the highest quality of care and is ready to support both patients and prescribers with any inquiries regarding this formulation.

The topical gel formulation containing Metronidazole 1%, Niacinamide 3%, Panthenol 1%, and Tretinoin 0.025% is designed for targeted skin treatment. Metronidazole is an antibiotic and antiprotozoal medication that is effective in treating inflammatory lesions of rosacea. Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help treat acne and other inflammatory skin conditions. Panthenol, or pro-vitamin B5, promotes skin healing and moisturization. Tretinoin, a derivative of vitamin A, is commonly used to treat acne and photoaging due to its ability to modulate cell proliferation and differentiation.

When using this combination gel, it is important to consider potential drug interactions. Tretinoin can increase the skin's sensitivity to sunlight and other sources of ultraviolet light, which can lead to more severe sunburn. Patients should be advised to apply sunscreen and wear protective clothing when outdoors. Concurrent use of other topical acne treatments, particularly those containing benzoyl peroxide, salicylic acid, or sulfur, may lead to excessive skin irritation or dryness. These should be used cautiously and spaced apart from the application of the tretinoin-containing gel.

Metronidazole may interact with anticoagulants such as warfarin, potentially enhancing their effect and increasing the risk of bleeding. Although systemic absorption of metronidazole from topical application is minimal, patients on anticoagulant therapy should be monitored for changes in prothrombin time or INR. Alcohol should be avoided during treatment with metronidazole, as it may produce a disulfiram-like reaction, even though this is more commonly associated with oral or systemic administration.

Niacinamide is generally well-tolerated and has a low risk of interactions when applied topically. However, patients should be aware that high doses of niacinamide taken orally can interact with certain medications, such as antihypertensive drugs and statins. Panthenol is also unlikely to interact with other medications when used topically, as it is a provitamin substance with minimal systemic absorption.

Patients should be advised to inform their healthcare providers of all medications they are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions. If irritation, redness, or other adverse reactions occur, use of the product should be discontinued, and a healthcare provider should be consulted. For any questions or concerns regarding this formulation or its use, please reach out to us at Bayview Pharmacy.

The Metronidazole 1%/Niacinamide 3%/Panthenol 1%/Tretinoin 0.025% Topical Gel is a compounded medication designed to deliver a combination of active ingredients directly to the skin. This formulation is intended to address a variety of skin conditions by leveraging the therapeutic properties of each component. The gel is dispensed through a pump mechanism, which ensures that a consistent and precise dose is delivered with each use, promoting adherence to treatment and optimizing outcomes.

Metronidazole is an antibiotic and antiprotozoal medication that is effective in treating inflammatory lesions of rosacea and certain other skin infections. When applied topically, it works by penetrating the skin to disrupt the DNA of the microorganisms causing the infection, thereby reducing inflammation and bacterial growth.

Niacinamide, also known as Vitamin B3, has anti-inflammatory properties that can help to calm the skin and reduce redness. It is beneficial for a variety of dermatological conditions, including acne, rosacea, and other inflammatory skin disorders. Niacinamide also helps to strengthen the skin's barrier function, improves skin texture, and can help to even out skin tone by inhibiting the transfer of pigment within the skin.

Panthenol, a provitamin of B5, acts as a moisturizer, drawing water into the skin and holding onto it. It helps to maintain skin softness and elasticity, promoting healing and providing a soothing effect. This makes it particularly useful for treating dry, rough, or damaged skin.

Tretinoin, a derivative of Vitamin A, is a powerful agent commonly used to treat acne and photoaging. It works by promoting the turnover of skin cells, which helps to unclog pores and prevent the formation of acne lesions. Additionally, tretinoin stimulates collagen production, which can reduce the appearance of fine lines and wrinkles, improving the overall texture and tone of the skin.

This unique combination of ingredients in a gel base allows for targeted application to affected areas, providing a multifaceted approach to skin therapy. The gel formulation is designed to be lightweight and is absorbed quickly by the skin, minimizing any residue or greasiness. This makes it suitable for use under makeup or in conjunction with other skincare products.

For patients and prescribers considering this formulation, it is important to note that while the combination of these ingredients can be highly effective, it is also essential to use the product as directed to avoid potential irritation or adverse effects. It is also recommended to apply sunscreen during the day while using this product, as tretinoin can increase the skin's sensitivity to sunlight. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to support you with your skincare needs.

This formulation, containing Metronidazole 1%, Niacinamide 3%, Panthenol 1%, and Tretinoin 0.025%, is primarily indicated for the management of various dermatological conditions such as rosacea, acne, and other inflammatory skin disorders. However, the unique combination of these active ingredients may also offer ancillary benefits due to their individual properties. Metronidazole, beyond its anti-inflammatory and antimicrobial effects, may help in wound healing, making the gel potentially useful for skin recovery after minor injuries or procedures. Niacinamide, known for its skin brightening effects and ability to improve the skin's barrier function, can be beneficial for addressing hyperpigmentation and boosting overall skin hydration, which could be advantageous for individuals with dull or dehydrated skin.

Panthenol, a provitamin of B5, has moisturizing and healing properties and can aid in maintaining skin elasticity and softness. Its inclusion in the formulation might provide relief from minor skin irritations and improve skin texture. Tretinoin, a retinoid, is well known for its ability to promote skin cell turnover, which can help to not only treat acne but also reduce the appearance of fine lines and wrinkles, making this formulation potentially useful as part of an anti-aging skincare regimen. The combination of these active ingredients in a gel form, dispensed through a pump mechanism, allows for ease of use, enabling consistent dosing and targeted application which can be very appealing for patients seeking a user-friendly treatment option.

It is important for patients and prescribers to note that while this formulation offers a multitiered approach to skin therapy, each ingredient's suitability should be evaluated on an individual basis, considering skin type, existing conditions, and overall treatment objectives. It's also vital to be aware that tretinoin can increase skin sensitivity to sunlight, so concurrent use of a broad-spectrum sunscreen is important. Given that the vehicle is a gel, this formulation may be best suited for those with oily or combination skin types, as gels are typically lighter and less occlusive than creams or ointments. For more tailored advice or to discuss the potential uses and contraindications of this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to support both patients and healthcare providers with specific concerns and questions regarding personalized dermatological care.