Lidocaine HCl 10%/Phenylephrine HCl 1%/Tetracaine HCl 5.69% Topical Cream is a compounded medication formulated to provide localized relief from various conditions. This topical cream combines the anesthetic effects of Lidocaine and Tetracaine with the vasoconstrictive properties of Phenylephrine. Lidocaine, a well-known local anesthetic, works by blocking sodium channels, thereby reducing the sensation of pain. Tetracaine, another potent local anesthetic, enhances the formulation's numbing effect, making it particularly useful for procedures requiring a deeper or more prolonged anesthesia. Phenylephrine is a selective alpha-1 adrenergic receptor agonist, which induces vasoconstriction, reducing swelling and bleeding at the site of application. This can be particularly beneficial in procedures where minimizing bleeding is important.

The cream is designed to be dispensed in a pump mechanism, which allows for a controlled and hygienic application. This delivery system ensures that the correct dose is administered each time, reducing the risk of overuse or contamination. The semisolid preparation is intended for external use only and should be applied to the skin as directed by a healthcare provider.

This combination cream is often used in medical settings such as dermatology, plastic surgery, and otolaryngology for procedures that require topical anesthesia. It may also be used to manage symptoms of certain chronic pain conditions where localized relief is desired. The vasoconstrictive effect of Phenylephrine makes it useful in managing superficial bleeding in minor cuts, abrasions, or during surgical procedures.

Patients and prescribers should be aware that this formulation is specifically compounded for individual needs and may not be suitable for everyone. It is important to use this medication as directed by a healthcare professional and to discuss any potential side effects or contraindications, especially in patients with a history of heart disease, hypertension, or hypersensitivity to any of the active ingredients. For any questions or concerns regarding this formulation or its appropriate use, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide guidance and support to ensure safe and effective treatment outcomes.

The topical cream formulation containing Lidocaine HCl 10%, Phenylephrine HCl 1%, and Tetracaine HCl 5.69% is designed for localized treatment and can be used for various conditions such as minor skin procedures, superficial anesthesia, or vasoconstriction of the skin. Lidocaine and Tetracaine are local anesthetics that work by blocking nerve signals in the body, providing numbing effects, while Phenylephrine is a vasoconstrictor that narrows the blood vessels in the area of application, reducing swelling and bleeding.

When using this topical cream, it is important to consider potential drug interactions. Lidocaine, being a local anesthetic, may interact with other local anesthetics or medications that affect cardiac function due to its potential systemic absorption, especially when applied to large areas or used over prolonged periods. Caution is advised when using this cream in conjunction with antiarrhythmic drugs such as amiodarone or beta-blockers, as there may be an increased risk of cardiac effects.

Phenylephrine, as a vasoconstrictor, can interact with monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and other sympathomimetic drugs, potentially leading to hypertensive reactions. Patients taking these medications should consult with their healthcare provider before using this cream. Additionally, the use of this cream with other vasoconstrictors should be approached with caution to avoid excessive vasoconstriction.

Tetracaine is another local anesthetic that can potentiate the effects of other local anesthetics. The combination of Lidocaine and Tetracaine in this formulation should be used with caution in patients receiving other local anesthetics or agents that may increase the risk of systemic toxicity, such as anti-epileptic drugs or cimetidine.

It is also important to consider the potential for systemic absorption and interaction with other medications that the patient may be taking. Patients should inform their healthcare provider of all medications they are currently using, including prescription drugs, over-the-counter medications, and herbal supplements, to assess for any potential interactions.

Patients with pre-existing heart conditions, liver disease, or those who are pregnant or breastfeeding should discuss the use of this cream with their healthcare provider, as these conditions may affect the metabolism and excretion of the active ingredients, leading to an increased risk of systemic side effects.

As with any medication, allergic reactions are possible. Patients with a known allergy to any of the active ingredients, Lidocaine, Phenylephrine, or Tetracaine, or to other local anesthetics of the amide or ester type, should not use this cream. Signs of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If any of these symptoms occur, use of the cream should be discontinued immediately, and medical attention should be sought.

If you have any questions or require further information regarding the use of this topical cream formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The Lidocaine HCl 10%/Phenylephrine HCl 1%/Tetracaine HCl 5.69% Topical Cream is a compounded medication that combines the properties of three active pharmaceutical ingredients (APIs) to provide localized relief from various conditions. This cream is formulated to be applied topically, where it exerts its effects directly on the skin and underlying tissues.

Lidocaine HCl is a local anesthetic that works by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect and relief from pain. At a concentration of 10%, Lidocaine HCl is effective in numbing the targeted area quickly and is commonly used for procedures that require local anesthesia or for the relief of localized pain and discomfort.

Phenylephrine HCl is a vasoconstrictor that acts on alpha-adrenergic receptors in the vascular smooth muscle, causing the blood vessels to constrict. This can help to reduce swelling and bleeding in the applied area, making it particularly useful in situations where control of bleeding is desired, such as during minor surgical procedures or in the treatment of hemorrhoids. The 1% concentration of Phenylephrine HCl in this formulation aids in providing these effects without significant systemic absorption.

Tetracaine HCl is another local anesthetic, similar to Lidocaine, but with a longer duration of action. It also works by blocking sodium channels, leading to a loss of sensation in the area of application. The inclusion of 5.69% Tetracaine HCl in the cream enhances the overall anesthetic effect, providing a more profound and prolonged numbing sensation, which can be particularly beneficial for longer procedures or when extended pain relief is required.

The cream is dispensed in a pump mechanism, which allows for a controlled and hygienic application. This dosage form ensures that the correct amount of medication is applied to the affected area, minimizing waste and reducing the risk of contamination. The semisolid preparation is designed to spread easily on the skin, allowing for quick absorption of the APIs and facilitating the onset of their therapeutic effects.

This compounded topical cream is indicated for use in various disease states where local anesthesia, vasoconstriction, and pain relief are required. It may be used prior to minor surgical procedures, during the removal of lesions, for the management of acute pain due to injuries, or in other situations where the properties of the APIs are beneficial. The combination of Lidocaine, Phenylephrine, and Tetracaine in a single formulation provides a multifaceted approach to treatment, addressing pain, swelling, and bleeding simultaneously.

For patients and prescribers interested in using this formulation, it is important to understand the pharmacological actions, potential side effects, and appropriate application techniques. If you have any questions or require further information about this compounded medication, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with your needs.

The topical cream formulation consisting of Lidocaine HCl 10%, Phenylephrine HCl 1%, and Tetracaine HCl 5.69% may be primarily indicated for localized anesthesia and vasoconstriction, but it may also provide utility in several off-label or ancillary uses. It is important to note, however, that the potential other uses discussed herein should always be considered with caution and under the advice of a healthcare professional. The contained active ingredients, being potent in their respective actions, should be employed only with proper knowledge of their pharmacological effects.

Lidocaine, a local anesthetic, is known for its effectiveness in providing rapid and duration-sustained numbness to localized areas, making this formulation potentially beneficial for surface anesthesia in minor surgical procedures that require skin incision or needle insertion. This cream could also be employed for pain relief in conditions that involve skin irritation or injury, like sunburns, insect bites, or minor burns, as lidocaine can alleviate the discomfort associated with these conditions.

Phenylephrine is a vasoconstrictor, which limits bleeding by constricting blood vessels in the applied area. This property might make the topical formulation helpful during minor aesthetic procedures, such as microblading or tattoo placement, where controlling capillary bleeding can be advantageous. In similar outpatient procedures, such as dermatologic surgeries, the phenylephrine component could be utilized to improve visibility and reduce minor procedural bleeding.

Tetracaine, another local anesthetic in the mixture, provides a longer duration of action compared to lidocaine, and its presence may lengthen the overall anesthetic effect of the cream. This could allow for extended procedures or those where reapplication of an anesthetic would be disruptive. Furthermore, the combined anesthetic effect of lidocaine and tetracaine could be beneficial in managing painful chronic ulcers or other painful dermatological conditions, providing a symphony of prolonged pain relief.

This formulation is dispensed in a pump mechanism, offering a sanitary and precise method for application, thus minimizing the risk of contamination and ensuring consistent dosing. While this increases the convenience and efficacy of the medication, it is critical to follow the specific instructions provided by healthcare professionals regarding the amount to be applied and the frequency of application, to avoid systemic absorption or local side-effects that may occur from excessive use. Although this topical cream has the potential for various applications, any use beyond the primary indications should be embarked upon following a thorough evaluation by a healthcare provider.

If you, as a patient or a prescriber, have any questions regarding additional potential uses, appropriate dosing, or the suitability of this formulation for a specific application, our team at Bayview Pharmacy is well-equipped to provide support and guidance. Reach out to us for in-depth pharmaceutical counsel, and to ensure the safe and effective use of this multi-ingredient topical cream.