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Levothyroxine Sodium 15 mcg/ml Oral Liquid

Levothyroxine Sodium 15 mcg/ml Oral Liquid is a specially compounded medication designed for oral use, offering a precise and consistent dose of levothyroxine to patients. This liquid formulation is particularly beneficial for individuals who have difficulty swallowing solid dosage forms, including pediatric and geriatric patients. Levothyroxine is a synthetic thyroid hormone, which is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used to treat or prevent certain types of goiters, as well as for the management of thyroid cancer. The liquid form ensures that patients who are unable to take tablets or capsules can still receive their necessary medication in an easily ingestible and accurately measured dose.

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Levothyroxine Sodium
Oral Liquid
65b01792abd0ce23fdac4699
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Formula Information

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Levothyroxine Sodium is a synthetic form of thyroxine, a hormone normally secreted by the thyroid gland. This medication is essential for individuals with hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. Levothyroxine Sodium works by replacing or supplementing the thyroxine that the thyroid gland cannot produce in sufficient quantities, thereby normalizing the body's energy and metabolism levels. The 15 mcg/ml oral liquid formulation of Levothyroxine Sodium is specifically designed to provide a precise dosage in a form that is easy to ingest, particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as young children, the elderly, or those with dysphagia.

The liquid form ensures that the medication can be accurately measured to the specific dose prescribed by a healthcare provider, which is crucial since thyroid hormone levels must be carefully balanced in the body. Over- or under-dosing can lead to significant health issues. The oral liquid is also faster to absorb compared to solid dosage forms, which may be advantageous in certain clinical situations. It is important for patients to take this medication on an empty stomach, typically 30 minutes to an hour before breakfast, to ensure optimal absorption. Consistency in the timing of the dose is also important for maintaining stable thyroid hormone levels.

For prescribers, it is essential to start with a low dose of Levothyroxine Sodium and titrate up as needed based on the patient's thyroid function tests. Regular monitoring of thyroid-stimulating hormone (TSH) and thyroxine (T4) levels is necessary to ensure the dose remains therapeutic. Adjustments to the dose should be made cautiously and based on clinical response and laboratory parameters. This liquid formulation allows for smaller dose adjustments compared to tablet forms, which can be particularly useful in the pediatric and geriatric populations where dose requirements may be more nuanced.

Patients should be counseled on the importance of adherence to their medication regimen and advised to report any symptoms of hyperthyroidism or hypothyroidism to their healthcare provider. These symptoms may include, but are not limited to, palpitations, weight loss, anxiety, fatigue, and cold intolerance. Additionally, patients should be informed that certain medications and supplements, including calcium and iron, can interfere with the absorption of Levothyroxine Sodium and should be taken several hours apart from this medication.

Bayview Pharmacy is committed to providing high-quality compounded medications tailored to meet individual patient needs. Our team of compounding pharmacists is available to answer any questions and provide guidance on the use of Levothyroxine Sodium 15 mcg/ml Oral Liquid. If you have any questions or require further information, please do not hesitate to reach out to us.

Drug Interactions

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Levothyroxine sodium is a synthetic form of the thyroid hormone thyroxine (T4) and is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used to treat or prevent certain types of goiters and, as a diagnostic agent, in thyroid function tests. When considering the use of levothyroxine sodium 15 mcg/ml oral liquid, it is crucial to be aware of potential drug interactions that can affect the efficacy of the medication or the health of the patient.

One of the most significant interactions occurs with antacids, calcium, and iron supplements, which can bind to levothyroxine and reduce its absorption. To avoid this interaction, levothyroxine should be taken on an empty stomach, typically 30 to 60 minutes before breakfast, and these supplements should be taken at least 4 hours after levothyroxine administration. Similarly, foods such as soybean flour, cottonseed meal, walnuts, dietary fiber, and grapefruit juice may decrease the absorption of levothyroxine and should not be consumed within several hours of taking the medication.

Other medications that can affect levothyroxine metabolism include proton pump inhibitors (PPIs), histamine H2 receptor antagonists, and sucralfate, which may decrease its absorption. Conversely, certain drugs like phenytoin, carbamazepine, barbiturates, rifampin, and sertraline can increase the metabolism of levothyroxine, necessitating a dosage adjustment. Additionally, medications such as amiodarone, lithium, and tyrosine kinase inhibitors can affect thyroid function and may alter the required dose of levothyroxine.

Levothyroxine can also affect the action of oral anticoagulants (blood thinners) like warfarin, increasing the risk of bleeding. Close monitoring of coagulation parameters and possible adjustment of the anticoagulant dose may be required. Diabetes medications may also need adjustment, as levothyroxine can increase blood sugar levels. Patients with diabetes should monitor their blood glucose levels closely when starting or adjusting levothyroxine therapy.

It is important to note that this is not an exhaustive list of all potential drug interactions with levothyroxine. Patients should inform their healthcare provider of all medications, supplements, and over-the-counter products they are taking to ensure safe and effective use of levothyroxine sodium oral liquid. If you have any questions or concerns about drug interactions with levothyroxine sodium or its use in treating thyroid-related conditions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Levothyroxine Sodium is a synthetic form of thyroxine, a hormone naturally produced by the thyroid gland. This hormone is crucial for regulating the body's energy and metabolism. When the thyroid gland does not produce enough thyroxine, a condition known as hypothyroidism occurs. Levothyroxine Sodium works by replacing the deficient thyroxine in the body, thereby normalizing the body's metabolic processes. The 15 mcg/ml oral liquid formulation of Levothyroxine Sodium is designed to provide a precise dosage of the medication in a form that is easy to ingest, particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as children, the elderly, or those with dysphagia.

The liquid formulation ensures that the medication can be accurately measured and administered, which is critical for maintaining the narrow therapeutic index of Levothyroxine Sodium. Consistent dosing is essential because small variations in dose can lead to significant changes in the body's metabolic rate. The oral liquid is absorbed into the bloodstream through the gastrointestinal tract after ingestion. Once absorbed, it functions in the same way as the hormone produced by the thyroid gland, binding to thyroid hormone receptors in the nucleus of cells and affecting the transcription of genes involved in metabolic regulation.

By restoring the proper levels of thyroid hormone in the body, Levothyroxine Sodium helps to alleviate the symptoms of hypothyroidism, which can include fatigue, weight gain, cold intolerance, and slow heart rate, among others. It is important for patients and prescribers to understand that treatment with Levothyroxine Sodium requires regular monitoring of thyroid function tests to ensure the dosage is appropriate and to adjust it as necessary. The goal of therapy is to achieve and maintain euthyroidism, where thyroid hormone levels are within the normal range, and the patient is free of symptoms.

For those interested in using this formulation of Levothyroxine Sodium, it is important to note that consistency in the brand or source of levothyroxine is recommended, as different formulations may have varying bioavailability. Additionally, the absorption of the medication can be affected by certain foods and other medications, so it is important to take it on an empty stomach and at the same time each day. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to support both patients and prescribers with the information and guidance needed for effective treatment with Levothyroxine Sodium 15 mcg/ml Oral Liquid.

Other Uses

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Levothyroxine Sodium is a synthetic form of the thyroid hormone thyroxine and it is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce sufficient quantities of hormones. It is also used for the management of thyroid cancer and in the suppression of pituitary TSH (Thyroid Stimulating Hormone) to prevent the growth of benign thyroid nodules and enlarged thyroid glands (goiter). Moreover, this specific liquid formulation offers additional utility in several other contexts due to its unique dosage form.

Some of these alternate uses include but are not limited to, aiding in the titration process for those patients who are sensitive to small adjustments in dosage. The liquid form allows for precise increments or decrements of medication, which may be especially critical immediately after thyroid surgery or when managing thyroid cancer. Another use of this liquid formulation is in testing thyroid function. A physician might prescribe this easily adjustable liquid form of Levothyroxine during a suppression test, to help determine thyroid gland autonomy especially in the case of borderline hyperthyroidism.

For patients with certain gastrointestinal disorders, such as malabsorption syndromes, the liquid formulation can enhance absorption of the medication. These patients may not adequately absorb solid medicines due to their underlying condition, which can impair the effectiveness of their treatment. The liquid form can bypass certain absorption issues associated with solid formulations, thus ensuring appropriate medication blood levels are achieved. Additionally, this liquid formulation may be preferred for patients who have allergies to fillers or binders commonly found in tablet or capsule forms of medications.

Furthermore, this formulation can be used in instances where a patient requires a very low dose of Levothyroxine that is not readily available in commercial tablet strengths; it allows for accurate dosing that might otherwise be difficult to achieve. It is also suitable for patients with feeding tubes, where the liquid can be administered directly, ensuring those with such needs receive consistent thyroid hormone replacement therapy.

Note: The conversion from a tablet form to a liquid form should be monitored carefully, as bioavailability may differ and the dose might need adjustment. All potential uses outside of those directly related to thyroid hormone replacement should be discussed with a healthcare provider to ensure safety and efficacy. It is important to consult with a compounding pharmacist for any specific concerns or customization of dosage. The team at Bayview Pharmacy is always available to provide assistance and information to both patients and prescribers considering this formulation. Should you have any questions or require further support, please don't hesitate to reach out to us.

Frequently Asked Questions

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What is Levothyroxine Sodium 15 mcg/ml Oral Liquid?

Levothyroxine Sodium 15 mcg/ml Oral Liquid is a specially compounded medication that provides a consistent dose of levothyroxine, a thyroid hormone, in a liquid form for oral administration. It is designed for patients who need precise dosing and may have difficulties swallowing traditional solid dosage forms.

Who might need Levothyroxine Sodium 15 mcg/ml Oral Liquid?

This liquid medication is suited for individuals such as children, the elderly or anyone who has difficulty swallowing pills. It's also beneficial for patients who require exact dosing that cannot be easily achieved with tablet forms of the medication.

How should this medication be taken?

Levothyroxine Sodium Oral Liquid should be taken as prescribed by your healthcare provider. The liquid form allows for the medication to be measured with a syringe or dropper for accurate dosing. It is typically taken once daily on an empty stomach, at least 30 minutes to an hour before breakfast. Follow the specific instructions provided by your pharmacist or doctor.

Can the dose be adjusted?

Yes, the dose of Levothyroxine Sodium Oral Liquid can be precisely adjusted according to the needs of the individual patient. This should always be done under the supervision and advice of a healthcare professional.

What are the advantages of Levothyroxine Sodium 15 mcg/ml Oral Liquid over tablet form?

The liquid formulation offers greater ease of swallowing, more accurate dosing and faster absorption. It is particularly advantageous for patients who have trouble with tablets or capsules and for those who require small dosage adjustments.

Should this medication be refrigerated?

You should follow the storage instructions provided by your pharmacist or refer to the label on the medication. In general, storing the medication at room temperature away from light and moisture is recommended, unless instructed otherwise.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses. Consult your healthcare provider for specific guidance.

Are there any potential side effects of taking Levothyroxine Sodium Oral Liquid?

Just like with tablet forms of levothyroxine, potential side effects can include symptoms of hyperthyroidism such as increased heart rate, anxiety, tremors, and unwanted weight loss. Inform your doctor immediately if you experience any unusual symptoms.

Can Levothyroxine Sodium Oral Liquid interact with other medications?

Yes, levothyroxine can interact with other medications, so it is crucial to inform your healthcare provider of all other medications you are taking. Some drugs may need to be taken at different times than levothyroxine to avoid interactions.

What if I experience difficulty measuring the dose?

If you're having trouble accurately measuring the dose, contact your pharmacist for advice. They can provide you with the appropriate measuring device and demonstrate how to measure the dose correctly.

How long do I need to take Levothyroxine Sodium Oral Liquid?

Levothyroxine is typically a long-term medication, often taken for life. The duration of treatment will depend on the nature of your thyroid disorder and the recommendation of your healthcare provider. Regular monitoring of thyroid levels is necessary to ensure the medication is working effectively.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.