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Glycerin 10%/Lactic Acid 5%/Urea 25% Topical Ointment

The Glycerin 10%/Lactic Acid 5%/Urea 25% Topical Ointment is a specialized semi-solid formulation designed for external application to the skin. This ointment is dispensed in a tube and provides a greasy or oily base, which facilitates the delivery of its active ingredients directly to the affected area. The combination of glycerin, lactic acid, and urea works synergistically to hydrate, exfoliate, and moisturize the skin, making it particularly effective in treating a variety of dermatological conditions.

This formulation is commonly used in the management of dry skin conditions, such as xerosis, and is also beneficial in treating ichthyosis, a condition characterized by dry, scaly skin. Additionally, it is effective in softening and reducing the thickness of hyperkeratotic skin disorders, including keratosis pilaris and psoriasis, where excessive skin build-up occurs. The ointment's moisturizing properties also make it suitable for aiding in the healing of minor wounds and skin inflammation.

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Lactic Acid
Urea
Topical Ointment
65ad6d82dc5e0e719eb997e2
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Formula Information

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Glycerin 10%/Lactic Acid 5%/Urea 25% Topical Ointment is a specialized dermatological compound designed to address a variety of skin conditions through its unique combination of active ingredients. Glycerin, a well-known humectant, is included at a 10% concentration to attract moisture to the skin, thereby enhancing hydration and maintaining the skin's barrier function. This is particularly beneficial for patients with dry or flaky skin, as it helps to prevent moisture loss and improves the overall texture and suppleness of the skin.

Lactic Acid, present at a 5% concentration, serves a dual purpose. As an alpha hydroxy acid (AHA), it gently exfoliates the uppermost layer of the skin, removing dead skin cells and promoting cell turnover. This can help to improve the appearance of the skin, reducing the signs of aging such as fine lines and wrinkles. Additionally, Lactic Acid has been shown to have hydrating properties, further contributing to the ointment's moisturizing effects. Its exfoliating action also makes it useful in the treatment of keratosis pilaris and other conditions characterized by the buildup of keratin.

Urea, at a substantial 25% concentration, is a potent keratolytic and moisturizing agent. It works by softening and dissolving the keratin in the skin, which makes it highly effective in treating thickened skin conditions such as psoriasis, ichthyosis, and hyperkeratosis. Urea also enhances the penetration of other medications and helps to retain moisture, providing relief from dryness and itching.

The ointment is formulated as a semi-solid preparation, which allows for a sustained release of the active ingredients and ensures that they remain in contact with the skin for an extended period. The greasy or oily base of the ointment not only facilitates the delivery of the active ingredients but also provides an occlusive layer that helps to lock in moisture and protect the skin from external irritants. This makes the formulation particularly suitable for patients with dry, cracked, or inflamed skin, as it can promote healing and provide a barrier against further damage.

Overall, this Glycerin/Lactic Acid/Urea ointment is a versatile compound that can be used to treat a range of dermatological conditions. Its moisturizing, exfoliating, and protective properties make it an excellent choice for patients with dry skin conditions, hyperkeratosis, and other disorders requiring enhanced skin hydration and turnover. It is important for both patients and prescribers to be aware of the potential for skin irritation, particularly with the use of Lactic Acid, and to monitor for any adverse reactions. As with any compounded medication, it should be used under the guidance of a healthcare professional.

If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing you with the highest level of care and support.

Drug Interactions

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The formulation you have described contains glycerin, lactic acid, and urea, which are commonly used as topical agents for their hydrating and keratolytic properties. Glycerin is a humectant that attracts water to the skin, lactic acid acts as a mild exfoliant and moisturizer, and urea is a component of the skin's natural moisturizing factor and has keratolytic properties. This combination is often used to treat dry, scaly skin conditions such as eczema, psoriasis, keratosis, and ichthyosis.

When considering drug interactions for a topical ointment containing glycerin, lactic acid, and urea, it is important to note that systemic absorption is generally minimal. However, there are still potential interactions that should be considered. For instance, concurrent use of other topical medications that have exfoliating or irritating effects, such as retinoids or strong acids, may increase the risk of skin irritation. It is advisable to space the application of different topical treatments to avoid such interactions.

Patients should be aware that the use of occlusive dressings over the area where the ointment has been applied can increase the absorption of the active ingredients, potentially leading to increased effects or irritation. Additionally, the presence of lactic acid in the formulation may cause stinging or burning sensations when applied to broken or inflamed skin. Therefore, caution should be exercised when applying the ointment to open wounds or areas of active skin breakdown.

It is also important to consider the potential for interactions with other skin care products, such as soaps, cleansers, and cosmetics that have a high alcohol content or other ingredients that may cause drying or irritation. These products may exacerbate the drying effects of the ointment or lead to increased irritation.

For prescribers, it is crucial to review the patient's current medication list, including over-the-counter products and supplements, to identify any possible interactions. Additionally, prescribers should inquire about the patient's use of any other topical products to ensure compatibility with the glycerin/lactic acid/urea ointment.

Patients should be instructed to inform their healthcare provider of all the products they are using on their skin to avoid potential interactions. If there are any concerns or questions regarding the use of this topical ointment or its compatibility with other medications or products, please reach out to us at Bayview Pharmacy for further guidance and information.

How Does it Work

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The Glycerin 10%/Lactic Acid 5%/Urea 25% Topical Ointment is a specialized dermatological formulation designed to provide relief and treatment for a variety of skin conditions. This semi-solid formulation is dispensed in a tube and is intended for external application to the skin. The ointment base is greasy or oily, which not only facilitates the delivery of the active ingredients to the affected area but also provides a protective barrier that helps to retain moisture and enhance the healing process.

Glycerin, also known as glycerol, is a humectant, which means it has the ability to attract water from the surrounding environment and the lower layers of the skin into the outer layer of the skin. This property helps to hydrate the skin, relieve dryness, and maintain the skin's barrier function. The 10% concentration in this ointment ensures that sufficient glycerin is present to exert its moisturizing effects without causing irritation.

Lactic Acid, a type of alpha-hydroxy acid (AHA), serves multiple purposes in this formulation. At a 5% concentration, it acts as a mild exfoliant, helping to remove dead skin cells from the surface of the skin, which can improve skin texture and promote a more even skin tone. Additionally, lactic acid has hydrating properties and can help to increase the skin's natural barrier function, reducing water loss and keeping the skin moisturized.

Urea, at a 25% concentration, is a potent keratolytic and humectant. It works by softening and dissolving the keratin in the skin, which makes it very effective in treating thick, rough, and scaly skin conditions. Urea also enhances the penetration of other active ingredients and increases the skin's capacity to hold moisture, leading to improved hydration. Its exfoliating and hydrating actions make it particularly useful in treating conditions like eczema, psoriasis, corns, and calluses, where excessive skin build-up is a problem.

Together, these three active ingredients provide a comprehensive approach to treating dry, scaly, and itchy skin conditions. The ointment's moisturizing and exfoliating properties help to restore the skin's natural barrier, relieve symptoms, and promote healing. This formulation is particularly beneficial for patients with conditions such as eczema, psoriasis, ichthyosis, and keratosis, as well as for those with general dry skin issues.

For optimal results, the ointment should be applied to the affected area as directed by a healthcare provider. It is important to use this medication regularly to achieve the best outcome. Patients should be advised that they may experience a mild stinging or burning sensation upon application, which is generally transient. If severe irritation occurs, use should be discontinued, and a healthcare provider should be consulted. As with any medication, it is crucial to follow the prescribed instructions and not to use it for longer than recommended.

If you have any questions about this formulation or its use in treating specific skin conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your dermatological health.

Other Uses

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The glycerin 10%/lactic acid 5%/urea 25% topical ointment has been primarily formulated for the treatment of various skin conditions such as severe dryness, hyperkeratotic skin disorders, eczema, psoriasis, ichthyosis, and keratosis pilaris. The potent combination of humectants and keratolytic agents in this ointment is highly effective in hydrating and exfoliating the skin, promoting the removal of dead skin cells and leading to smoother, softer skin. Moreover, urea, a component recognized for its hydrating properties, can aid in the healing of cracked or thickened skin, making this formulation beneficial for those with rough, scaly skin patches resulting from xerosis or calluses.

Apart from these therapeutic uses, the ointment may serve additional purposes in skincare. For instance, its hydrating effects can improve the overall appearance of the skin, which may be advantageous for patients seeking a more cosmetically appealing skin texture. Some may also find this ointment to be an effective adjunct therapy for minimizing the discomfort associated with tight and itchy skin, commonly experienced with dermatitis. Furthermore, due to the exfoliating action provided by lactic acid, this formulation might be used to help prepare the skin before the application of other topical treatments, enhancing their absorption and effectiveness.

It is worth noting that while the ointment has a wide range of potential applications, it is imperative to use it under the guidance of a healthcare professional, especially because the high concentration of urea may not be suitable for all skin types and can cause irritation or sensitivity in some individuals. It is also not intended for use on open wounds or on facial skin, unless specifically directed by a health care provider. The occlusive nature of the greasy base can be beneficial for trapping moisture in the skin, but it may also be heavy for some, indicating that those with acne-prone or oily skin should exercise caution to prevent exacerbation of their condition.

For any questions or for more information on the safe and effective use of this formulation, or to discuss alternative treatment options that may be better suited for individual patient needs, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is ready to provide the necessary support and guidance, ensuring that you or your patients receive the most appropriate care for healthier skin outcomes.

Frequently Asked Questions

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What is Glycerin 10%/Lactic Acid 5%/Urea 25% Topical Ointment used for?

This compounded formulation is typically used to treat various skin conditions that require intense moisturization and exfoliation. It can help manage symptoms associated with dry, rough, and scaly skin, eczema, psoriasis, and keratosis pilaris. The ingredients work together to hydrate the skin, remove dead skin cells, and improve the skin's overall texture and appearance.

How often should I apply this topical ointment?

The frequency of application will depend on the specific condition being treated and the recommendation of your healthcare provider. Generally, this topical ointment may be applied once or twice daily or as directed by your healthcare professional.

Can this ointment be used on broken skin or open wounds?

This ointment is designed for external application on intact skin. It should not be applied to open wounds, cuts, or any skin that is broken without prior consultation with a healthcare provider as it may cause irritation or slow the healing process.

Is this ointment suitable for all skin types?

While this ointment is beneficial for dry and rough skin types, its suitability varies from person to person. Those with sensitive skin or specific allergies should consult their healthcare provider before use. A patch test can also help determine if the ointment is suitable for your skin type.

Are there any known side effects of using this topical ointment?

Some possible side effects can include localized skin irritation, redness, and itching. If you experience severe or persistent side effects, discontinue use and consult your healthcare provider.

Can this formulation be used during pregnancy or breastfeeding?

Always consult with your healthcare provider before using this formulation during pregnancy or while breastfeeding to ensure it is safe for you and your baby.

How should I store this topical ointment?

Store the ointment in a cool, dry place away from direct sunlight and heat. Keep the tube tightly closed when not in use to prevent the medication from drying out or becoming contaminated.

Can I use cosmetics or other skincare products over this ointment?

It is best to wait until the ointment is fully absorbed into your skin before applying cosmetics or other skincare products. Consult with your healthcare provider or a dermatologist for advice on using other products in conjunction with this medication.

Is it necessary to use sunscreen when using this compounded ointment?

Yes, using sunscreen is important as ingredients like lactic acid can make your skin more sensitive to sunlight. Applying a broad-spectrum sunscreen with an SPF of 30 or higher is recommended when going outdoors.

What should I do if I miss a dose of the ointment?

If you miss a dose, apply the ointment as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra ointment to make up for the missed dose.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.