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Formulas

Enrofloxacin 100 mg/ml Oral Liquid

Enrofloxacin 100 mg/ml Oral Liquid is a specially compounded medication designed for oral use, offering a precise and user-friendly method for administering the active drug. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing pills or tablets, making it an ideal choice for pediatric, geriatric, or veterinary patients. Enrofloxacin is a fluoroquinolone antibiotic that is effective in treating a range of bacterial infections, including those affecting the respiratory and urinary tracts, skin, and gastrointestinal system. It is also used to combat infections in the ears and eyes, as well as to treat certain sexually transmitted diseases. This oral liquid ensures accurate dosing and is tailored to meet the specific needs of individual patients, providing a versatile solution for managing various bacterial disease states.

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Enrofloxacin
Oral Liquid
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Formula Information

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Enrofloxacin 100 mg/ml Oral Liquid is a specially compounded medication designed for oral administration to treat a variety of bacterial infections. This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require precise dosage adjustments that are not available in pre-manufactured tablet or capsule forms. The liquid formulation allows for flexible dosing and can be easily measured to ensure the patient receives the exact amount of medication prescribed by their healthcare provider.

Enrofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes necessary for DNA replication, transcription, repair, and recombination. This action results in the elimination of the bacterial infection. It is effective against a broad spectrum of Gram-negative and Gram-positive bacteria and is commonly used to treat respiratory tract infections, skin infections, urinary tract infections, and certain gastrointestinal infections caused by susceptible strains of bacteria.

It is important for patients and prescribers to be aware that the use of enrofloxacin should be based on susceptibility testing and it should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Overuse or misuse of antibiotics can lead to the development of antibiotic resistance. Patients should be advised to adhere to the prescribed dosage and duration of therapy to ensure the best possible outcome. Additionally, patients should be monitored for potential side effects, which may include gastrointestinal upset, central nervous system disturbances, and hypersensitivity reactions.

Our team at Bayview Pharmacy is committed to providing high-quality, customized medications to meet the unique needs of each patient. We are available to answer any questions and provide guidance to both patients and prescribers regarding the use of Enrofloxacin 100 mg/ml Oral Liquid. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us.

Drug Interactions

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Enrofloxacin is a fluoroquinolone antibiotic that is effective against a broad range of bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes necessary for DNA replication, transcription, repair, and recombination. This action leads to the death of the bacteria and resolution of the infection. Enrofloxacin is commonly used in veterinary medicine, but it is not approved for use in humans by the U.S. Food and Drug Administration (FDA). Therefore, it is important to note that this formulation is intended for veterinary use only.

When considering the use of enrofloxacin 100 mg/ml oral liquid, it is crucial to be aware of potential drug interactions that may affect the efficacy of the medication or the health of the patient. Enrofloxacin should not be administered concurrently with certain drugs that can interfere with its metabolism or action. For instance, the concurrent use of theophylline, a bronchodilator, and enrofloxacin may lead to increased theophylline levels due to decreased clearance, potentially causing toxicity. Careful monitoring of theophylline levels is advised if these drugs must be used together.

Antacids, sucralfate, iron supplements, and dairy products can bind to enrofloxacin and reduce its absorption, leading to decreased effectiveness. It is recommended to administer enrofloxacin at least 2 hours before or 4-6 hours after the administration of these agents. Similarly, multivitamins and mineral supplements containing calcium, magnesium, aluminum, or iron should also be spaced apart from enrofloxacin dosing.

Enrofloxacin may increase the risk of tendonitis and tendon rupture when used concurrently with corticosteroids. Caution is advised when considering this combination, especially in older animals or those with pre-existing tendon problems. Nonsteroidal anti-inflammatory drugs (NSAIDs) may also interact with enrofloxacin, potentially leading to increased risk of CNS stimulation and convulsive seizures. This is particularly important in animals with known seizure disorders.

Warfarin and other oral anticoagulants may have their effects potentiated by enrofloxacin, increasing the risk of bleeding. If an animal is receiving an anticoagulant, close monitoring of coagulation parameters and adjustment of the anticoagulant dose may be necessary. Additionally, enrofloxacin can alter the metabolism of other drugs by inhibiting cytochrome P450 enzymes, potentially leading to altered plasma levels of drugs metabolized by these pathways.

It is important to provide a complete medical history and list of all medications, including over-the-counter drugs and supplements, that the patient is receiving to the prescribing veterinarian. This will help to identify any potential interactions and allow for appropriate management. If you have any questions or concerns regarding the use of enrofloxacin 100 mg/ml oral liquid or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Enrofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone class, which is effective against a wide range of bacterial infections. The mechanism of action of enrofloxacin involves inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. By doing so, it prevents the bacteria from replicating and transcribing DNA, leading to the elimination of the bacterial infection. This makes enrofloxacin a potent choice for treating diseases caused by susceptible strains of bacteria.

The 100 mg/ml oral liquid formulation of enrofloxacin is designed to provide a high concentration of the medication for ease of dosing, particularly in situations where high doses are required or when the patient's weight necessitates a precise calculation of the dosage. The liquid form is especially beneficial for patients who have difficulty swallowing pills, such as young children, the elderly, or those with certain medical conditions that affect swallowing. It also allows for flexibility in dosing, as the medication can be accurately measured to the specific dose prescribed by a healthcare provider.

Enrofloxacin is used to treat a variety of infections, including those affecting the respiratory tract, urinary tract, gastrointestinal system, skin, and soft tissues. It is particularly useful in treating infections caused by Gram-negative bacteria, but it also has activity against some Gram-positive bacteria. The oral liquid formulation ensures that the medication is absorbed quickly and reaches the site of infection effectively, providing relief from symptoms and aiding in the recovery process.

It is important for patients and prescribers to be aware that enrofloxacin should only be used to treat bacterial infections and will not be effective against viral infections. Additionally, as with all antibiotics, it is crucial to complete the full course of therapy as prescribed to prevent the development of antibiotic resistance. Patients should be monitored for any signs of side effects, and any concerns should be promptly discussed with a healthcare provider.

For those interested in using this formulation of enrofloxacin, or if there are any questions regarding its use, dosing, or the diseases it treats, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is equipped with the knowledge and expertise to provide guidance and support to ensure the safe and effective use of this medication.

Other Uses

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Enrofloxacin 100 mg/ml Oral Liquid is a versatile antimicrobial agent primarily used in the treatment of a wide range of bacterial infections, targeting both Gram-negative and Gram-positive bacteria, and it is commonly utilized in the field of veterinary medicine. While the main indication for this oral liquid formulation is to combat bacterial infections, its use may extend to the management of conditions where bacteria have developed resistance to other antibiotics, provided that the causative organism is sensitive to enrofloxacin. This liquid formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as young animals, small breeds, or those with esophageal disorders. It can also be useful for the exact dosing that might be required for treatment of infections in avian patients, where precision is key.

This medication must be used under the guidance of a qualified veterinarian who will determine its suitability for off-label applications, considering the species-specific restrictions and potential adverse effects. In alternative therapeutic uses, enrofloxacin may be considered for prophylactic purposes in certain cases, to prevent infection in animals who are at high risk due to surgery, trauma, or exposure to known infectious agents. The formulation's high bioavailability and excellent tissue penetration make it effective in reaching various infection sites. However, it is crucial to note that use of antibiotics without proper justification can contribute to the development of resistance, and therefore, the decision to use enrofloxacin should always be based on sensitivity testing or veterinary expertise.

Pharmacists at Bayview Pharmacy are ready to provide extensive counseling on the appropriate usage, contraindications, potential side effects, interactions with other medications, and the importance of completing the prescribed course of treatment with enrofloxacin. We stress the importance of using this medication only for the species for which it is prescribed, as certain animals may be at risk for adverse effects, such as cartilage damage in growing animals or seizures in pets with CNS disorders. If you have any questions or require further information regarding the other uses of Enrofloxacin 100 mg/ml Oral Liquid or would like to discuss its suitability for treating your pet's specific condition, please do not hesitate to reach out to us. We are committed to providing personalized, well-informed advice to ensure the optimal welfare of your pet.

Frequently Asked Questions

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What is Enrofloxacin 100 mg/ml Oral Liquid?

Enrofloxacin 100 mg/ml Oral Liquid is a specially formulated antibiotic medication intended for oral use, designed to treat bacterial infections in various animals. It's prepared in a liquid form for easy administration and absorption.

How should Enrofloxacin Oral Liquid be administered?

The medication should be given orally, following the specific dosage instructions provided by a veterinarian. It can be dispensed directly into the mouth or mixed with a small amount of food, depending on the animal's preference and ease of administration.

Can this medication be given to any animal?

Enrofloxacin Oral Liquid is primarily used for pets like dogs and cats, but the suitability for different animal species should be determined by a veterinarian. Dosage and safety may vary among different animals, hence professional consultation is necessary.

Is a prescription required for Enrofloxacin Oral Liquid?

Yes, Enrofloxacin is a prescription medication, and a veterinarian's prescription is necessary to obtain and administer it legally and safely.

What if I miss a dose?

If you miss a dose, administer it as soon as you remember. However, if it's almost time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Are there any side effects associated with Enrofloxacin Oral Liquid?

While many animals tolerate Enrofloxacin well, some may experience side effects such as vomiting, diarrhea, or loss of appetite. Severe side effects could include changes in behavior or seizures. If you observe any adverse reactions, contact your veterinarian immediately.

How should this medication be stored?

The medication should be stored at room temperature, away from light and moisture. Keep the bottle tightly closed and out of reach of children and pets.

Can Enrofloxacin Oral Liquid be used for long-term treatment?

The duration of treatment with Enrofloxacin should be determined by your veterinarian based on the type and severity of the infection. Long-term use can lead to resistance or other issues, so it's important to follow your vet's guidance.

What should I do if an overdose occurs?

If you suspect an overdose, seek emergency veterinary medical treatment right away. Symptoms of overdose may include nausea, vomiting, or even seizures.

Can humans take Enrofloxacin 100 mg/ml Oral Liquid for their infections?

No, this medication is formulated specifically for veterinary use. Humans should not take medications prescribed for animals, and should consult a healthcare provider for appropriate treatments.

Does Enrofloxacin Oral Liquid interact with other medications?

Yes, Enrofloxacin can interact with other medications. It's important to inform your veterinarian about all the medications and supplements your pet is currently taking before starting any new medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.