This compounded rectal cream combines Benzocaine 1.5%, Phenol 1%, Quinine HCl 0.5%, Tannic Acid 3%, and Urea 0.5% in a semisolid preparation dispensed through a pump mechanism. This design allows for convenient and controlled application on localized skin areas, enhancing the treatment's effectiveness and absorption of active ingredients.

Benzocaine acts as a local anesthetic by blocking nerve signals in the affected area, providing relief from pain, itching, and discomfort commonly associated with rectal conditions. Its 1.5% concentration is effective in numbing the area without causing significant systemic absorption.

Phenol at a 1% concentration serves dual functions as an antiseptic and anesthetic. It helps to prevent infection by eliminating harmful microorganisms and further reduces pain through its numbing effects, complementing the action of Benzocaine.

Quinine HCl, included at 0.5%, possesses antispasmodic properties. It helps relieve muscle spasms and cramps in the rectal area, which can contribute to discomfort and pain in various anorectal disorders.

Tannic Acid, at a 3% concentration, functions as an astringent. It works by precipitating proteins on the skin's surface, which helps to reduce irritation, inflammation, and excessive moisture. This can be particularly beneficial in conditions that involve swollen or protruding tissues.

Urea at 0.5% acts as a keratolytic agent and moisturizer. It facilitates the penetration of other active ingredients by softening the skin and helps maintain skin hydration, promoting healing and comfort.

This formulation is designed to provide symptomatic relief for rectal conditions characterized by pain, inflammation, itching, and discomfort. The combination of anesthetic, antiseptic, antispasmodic, astringent, and moisturizing agents addresses multiple symptoms concurrently, potentially improving patient outcomes.

Patients are advised to use the cream as directed by their healthcare provider. The pump mechanism ensures accurate dosing and minimizes contamination risks. Before application, the affected

This compounded rectal cream formulation contains Benzocaine 1.5%, Phenol 1%, Quinine HCl 0.5%, Tannic Acid 3%, and Urea 0.5%, each contributing to its therapeutic effects. Benzocaine is a local anesthetic that provides pain relief by blocking nerve signals in the body. Phenol acts as an antiseptic and anesthetic, offering additional pain relief and reducing the risk of infection. Quinine HCl is known for its antimalarial properties but in this formulation, it may contribute to pain relief and muscle relaxation. Tannic Acid has astringent properties, which can help reduce inflammation and irritation. Urea is a keratolytic agent that helps to moisturize and soften the skin, enhancing the absorption of other active ingredients.

When considering drug interactions, it is important to note that the systemic absorption of these active ingredients is generally low when applied topically as directed. However, potential interactions may still occur, particularly if the cream is used over large areas of the body, on broken skin, or for prolonged periods. Patients using other topical medications should consult with their healthcare provider to avoid potential interactions that could alter the effectiveness of either treatment. For instance, the use of other local anesthetics or antiseptics concurrently with this cream may increase the risk of systemic toxicity or skin irritation.

Patients taking medications that affect the central nervous system, such as sedatives or muscle relaxants, should use this cream with caution, as the local anesthetic effects of Benzocaine and Phenol could potentially enhance CNS depression. Additionally, Quinine HCl, although present in a low concentration, may interact with medications that affect cardiac rhythm or those that are metabolized by the liver, such as certain antimalarials or antiarrhythmics. It is crucial for patients to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to assess any potential interactions.

For prescribers, it is important to consider the patient's overall medication regimen and health status when recommending this compounded cream. Special attention should be given to patients with a history of hypersensitivity to any of the active ingredients or related compounds. Monitoring for signs of local or systemic adverse reactions is advised, especially in patients with compromised skin integrity or those using the cream in conjunction with other topical or systemic therapies.

If you have any questions or need further information regarding the use of this compounded rectal cream, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any concerns or inquiries you may have.

This compounded rectal cream formulation combines Benzocaine, Phenol, Quinine HCl, Tannic Acid, and Urea to provide a multifaceted approach to treating discomfort and irritation in the rectal area. Each active ingredient plays a specific role in alleviating symptoms and promoting healing, making this preparation suitable for conditions such as hemorrhoids, anal fissures, and other forms of rectal irritation.

Benzocaine, a local anesthetic, works by blocking nerve signals in the body, providing temporary relief from pain and discomfort. By numbing the affected area, Benzocaine helps reduce the sensation of pain, allowing patients to experience relief from the discomfort associated with rectal conditions. This can be particularly beneficial for patients experiencing acute pain during bowel movements or while sitting.

Phenol acts as an antiseptic and anesthetic, further enhancing the pain-relieving properties of the cream. It helps to reduce the risk of infection by eliminating harmful microorganisms in the affected area. Additionally, Phenol's anesthetic properties complement those of Benzocaine, providing a more comprehensive pain management solution.

Quinine HCl is included for its antispasmodic properties, which can help alleviate muscle spasms and cramping in the rectal area. By reducing muscle contractions, Quinine HCl aids in minimizing discomfort and promoting relaxation of the affected tissues, which can be particularly beneficial for patients experiencing spasms due to rectal irritation or inflammation.

Tannic Acid, a natural astringent, works by constricting body tissues, which helps to reduce swelling and inflammation. This action is particularly useful in managing hemorrhoids, as it can help shrink swollen tissues and provide relief from itching and irritation. Tannic Acid also forms a protective layer over the affected area, which can help prevent further irritation and promote healing.

Urea is included in the formulation for its moisturizing properties. It helps to maintain skin hydration and integrity, which is crucial for healing and comfort. By keeping the skin moisturized, Urea aids in preventing dryness and cracking, which can exacerbate discomfort and delay healing in the rectal area.

The semisolid preparation is dispensed in a pump mechanism, allowing for convenient and controlled application. This design ensures that patients can apply the cream directly to the affected area with ease, ensuring that the active ingredients are delivered precisely where they are needed for optimal therapeutic effect. The pump mechanism also helps maintain the stability and integrity of the formulation by minimizing exposure to air and contaminants.

For both patients and prescribers, this compounded rectal cream offers a targeted approach to managing rectal discomfort and irritation. By combining multiple active ingredients with complementary actions, it provides a comprehensive solution that addresses pain, inflammation, and tissue integrity. If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. We are here to assist you with any inquiries or concerns you may have.

The Benzocaine 1.5%/Phenol 1%/Quinine HCl 0.5%/Tannic Acid 3%/Urea 0.5% Rectal Cream, dispensed in a semisolid form with a pump mechanism, is primarily designed for localized treatment and absorption of active ingredients through the skin. While its primary indications may include the treatment of specific rectal conditions, this formulation may also have other potential uses due to the properties of its individual components. Benzocaine, a local anesthetic, can provide temporary relief from pain and discomfort associated with minor skin irritations, burns, and insect bites. Phenol, known for its antiseptic properties, may help in reducing the risk of infection in minor cuts and abrasions. Quinine HCl, although primarily known for its antimalarial properties, may also be explored for its potential in alleviating nocturnal leg cramps, though this use should be approached with caution and under medical supervision due to possible side effects.

Tannic Acid, with its astringent properties, can be beneficial in managing minor skin irritations and reducing inflammation, making it potentially useful in treating conditions like diaper rash or minor sunburn. Urea, a keratolytic agent, can aid in moisturizing and softening the skin, which may be beneficial for patients with dry or rough skin conditions. The combination of these ingredients in a rectal cream may also offer symptomatic relief for hemorrhoids, anal fissures, or other anorectal disorders by providing analgesic, anti-inflammatory, and moisturizing effects. However, it is crucial for both patients and prescribers to consider the potential for allergic reactions or sensitivities to any of the components, and to use this formulation under appropriate medical guidance.

As with any compounded medication, the specific needs and medical history of the patient should be carefully evaluated to ensure the safe and effective use of this formulation. If you have any questions or require further information about the potential uses of this rectal cream, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.