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Formulas

Amphotericin B 10%/Terbinafine HCl 1%/Edetate Disodium 0.5% Vaginal Gel

Bayview Pharmacy's Amphotericin B 10%/Terbinafine HCl 1%/Edetate Disodium 0.5% Vaginal Gel is a specially formulated, gel-like semisolid medication. It is dispensed in a tube for easy and controlled application in the vaginal area. This compounded formulation is designed to treat a range of fungal infections, including Vulvovaginal Candidiasis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, and Onychomycosis. It provides both therapeutic effects and lubrication for various gynecological purposes.

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Amphotericin B
Terbinafine Hydrochloride
Edetate Disodium
Vaginal Gel
6427079ea64324af9051866e
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Formula Information

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This compounded formulation is a unique blend of Amphotericin B 10%, Terbinafine HCl 1%, and Edetate Disodium 0.5% in a gel-like semisolid form, specifically designed for vaginal application. It is dispensed in a tube for easy and controlled application, ensuring the delivery of medication directly to the affected area. This formulation is primarily used for the treatment of various fungal infections, including but not limited to Vulvovaginal Candidiasis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, and Onychomycosis.

Amphotericin B, one of the active ingredients, is a potent antifungal agent that functions by disrupting the cell membrane of the fungus, leading to its eventual death. Terbinafine HCl, another active ingredient, is an antifungal agent that inhibits the growth of the fungus, preventing it from spreading. Edetate Disodium, the third active ingredient, is an antifungal agent that works by inhibiting the fungus's ability to produce energy, thereby stunting its growth and proliferation.

The combination of these three agents in this formulation creates a powerful antifungal treatment that is effective in managing and treating the aforementioned fungal infections. The gel-like consistency of the formulation ensures that the medication is easily applied and stays in place, providing prolonged contact with the affected area for maximum therapeutic effects.

If you have any questions about this formulation, its application, or any other related concerns, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is equipped with the knowledge and expertise to assist you with your medication needs.

Drug Interactions

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This compounded formulation of Amphotericin B 10%/Terbinafine HCl 1%/Edetate Disodium 0.5% Vaginal Gel is a specialized treatment designed for the management of various fungal infections such as Vulvovaginal Candidiasis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, and Onychomycosis. The gel is dispensed in a tube for easy and controlled application in the vaginal area, providing both medication and therapeutic effects.

Amphotericin B, one of the active ingredients, is an antifungal agent that functions by inhibiting the growth of fungi. Terbinafine HCl, another active ingredient, is also an antifungal agent but it works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. The third active ingredient, Edetate Disodium, is an antifungal agent that operates by chelating calcium and magnesium ions, which are vital for fungal growth.

This formulation is applied topically to the affected area as directed by a healthcare provider. It's important to note that this formulation may cause irritation or a burning sensation at the application site. If any of these side effects occur, patients should immediately contact their healthcare provider. Furthermore, this formulation may interact with other medications, so patients should inform their healthcare provider of any other medications they are currently taking.

For any questions or concerns regarding this formulation, patients are encouraged to reach out to their healthcare provider or pharmacist for further information and guidance.

How Does it Work

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This compounded formulation is a unique blend of three active ingredients: Amphotericin B 10%, Terbinafine HCl 1%, and Edetate Disodium 0.5%. Each of these ingredients plays a crucial role in combating fungal infections. Amphotericin B, an antifungal agent, disrupts the cell membrane of fungi, inhibiting their growth and reproduction. Terbinafine HCl, another antifungal agent, works by directly inhibiting the growth of fungi. Lastly, Edetate Disodium, also an antifungal agent, contributes to the overall effectiveness of the formulation by preventing the growth of fungi.

This potent combination of active ingredients is designed to treat a variety of fungal infections, including but not limited to Vulvovaginal Candidiasis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, and Onychomycosis. The formulation is dispensed in a gel-like semisolid form, specifically designed for easy and controlled application in the vaginal area.

When using this formulation, it is crucial to adhere to the instructions provided by your healthcare provider. Typically, the gel should be applied to the affected area twice daily, or as directed by your healthcare provider. Prior to application, ensure your hands are clean to prevent further infection. Avoid contact with the eyes, nose, and mouth. If contact occurs, rinse the area thoroughly with water.

It's important to understand that this formulation may take several weeks to show its full effect. Therefore, it's crucial to continue using the gel as directed by your healthcare provider, even if symptoms seem to improve. If you experience any side effects such as redness, itching, or burning, it's important to contact your healthcare provider immediately.

If you have any questions or concerns about this formulation or its mechanism of action, don't hesitate to reach out to your healthcare provider or pharmacist. They can provide you with the most accurate and personalized advice based on your specific health situation.

Other Uses

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This compounded formulation of Amphotericin B 10%/Terbinafine HCl 1%/Edetate Disodium 0.5% Vaginal Gel is a specialized medication designed for the treatment of various fungal infections. It is specifically indicated for the treatment of Vulvovaginal Candidiasis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, and Onychomycosis. The gel-like semisolid formulation is dispensed in a tube for easy and controlled application in the vaginal area, providing both therapeutic effects and lubrication.

It is crucial to understand that this formulation should only be used for the conditions listed above. It should be applied to the affected area twice daily for a period of two weeks. Patients should be vigilant for any signs of irritation or a burning sensation in the affected area, which may be side effects of the medication. If these symptoms occur, it is recommended to discontinue use immediately and consult with a healthcare provider.

Another potential side effect of this formulation is temporary skin discoloration. Patients should be aware of this possibility and monitor their skin closely during treatment. If you have any questions or concerns about this formulation or its use, it is always advisable to consult with a healthcare professional for guidance.

Frequently Asked Questions

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What is the purpose of this compounded formulation of Amphotericin B 10%/Terbinafine HCl 1%/Edetate Disodium 0.5% Vaginal Gel?

This formulation is designed to deliver medication to the vaginal area for various gynecological purposes. It can provide therapeutic effects and lubrication, making it useful for treating a range of conditions.

How is this medication applied?

This medication is dispensed in a tube and is designed for easy and controlled application in the vaginal area. It is a semisolid gel-like formulation that can be applied as directed by a healthcare professional.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Amphotericin B, Terbinafine HCl, and Edetate Disodium. These ingredients work together to provide therapeutic effects.

What is the role of Amphotericin B in this formulation?

Amphotericin B is an antifungal medication that can treat various types of fungal infections. In this formulation, it helps to treat and prevent fungal infections in the vaginal area.

What is the role of Terbinafine HCl in this formulation?

Terbinafine HCl is also an antifungal medication that works by stopping the growth of fungus. It complements the action of Amphotericin B in this formulation.

What is the role of Edetate Disodium in this formulation?

Edetate Disodium is a chelating agent that helps to stabilize the formulation. It also aids in the absorption and effectiveness of the other active ingredients.

Can this formulation be used for lubrication?

Yes, this formulation can provide lubrication in the vaginal area, in addition to its therapeutic effects. However, it is primarily intended as a medication, not a personal lubricant.

Are there any side effects associated with this formulation?

As with any medication, there can be side effects. These can vary from person to person and may include irritation or discomfort in the application area. If you experience any severe or persistent side effects, you should contact your healthcare provider immediately.

Can this formulation be used during pregnancy?

Before using this formulation during pregnancy, it is important to discuss it with your healthcare provider. They can provide guidance based on your specific situation and the potential risks and benefits.

How should this medication be stored?

This medication should be stored at room temperature, away from light and moisture. Keep it out of reach of children and pets. Do not store in the bathroom. Do not freeze or expose to extreme heat.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.