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Amantadine HCl 8%/Amitriptyline HCl 5%/Baclofen 5%/Diclofenac Sodium 8%/Gabapentin 6%/Lidocaine 3% Topical Gel

This formulation is a compounded topical gel containing Amantadine HCl 8%, Amitriptyline HCl 5%, Baclofen 5%, Diclofenac Sodium 8%, Gabapentin 6%, and Lidocaine 3%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Amantadine HCl is an antiviral medication that also has uses in treating Parkinson's disease and certain types of pain. Amitriptyline HCl is a tricyclic antidepressant used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase energy level. Baclofen is a muscle relaxer and an antispastic agent. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. Gabapentin is used with other medications to prevent and control seizures. It is also used to relieve nerve pain following shingles (a painful rash due to herpes zoster infection) in adults. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

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Amantadine Hydrochloride
Amitriptyline Hydrochloride
Diclofenac Sodium
Gabapentin
Baclofen
Lidocaine Hydrochloride
Topical Gel
65300228769926b2cc885805
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Formula Information

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This formulation is a multi-ingredient topical gel designed to provide targeted relief for a variety of conditions. It contains Amantadine HCl 8%, Amitriptyline HCl 5%, Baclofen 5%, Diclofenac Sodium 8%, Gabapentin 6%, and Lidocaine 3%. Each of these active ingredients plays a crucial role in managing different symptoms and conditions.

Amantadine HCl is an antiviral medication that also has properties for treating Parkinson's disease and certain conditions caused by drugs or chemical agents. Amitriptyline HCl is a tricyclic antidepressant that can help manage chronic pain, particularly neuropathic pain. Baclofen is a muscle relaxant and antispastic agent, often used in the treatment of muscle symptoms caused by multiple sclerosis. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks.

Gabapentin is an anticonvulsant and nerve pain medication used to treat seizures and pain caused by shingles. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This can help patients manage pain and discomfort from conditions such as sunburn, insect bites, poison ivy, and minor cuts, scratches, or burns.

When combined in a topical gel, these ingredients can provide targeted relief for a variety of conditions. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This formulation is designed to be applied directly to the skin, allowing for targeted treatment and absorption of the active ingredients.

It's important to note that while this formulation can provide relief for a variety of conditions, it should be used under the guidance of a healthcare provider. Patients should discuss their symptoms and medical history with their provider to ensure this formulation is the right choice for their treatment plan.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Drug Interactions

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This formulation contains a combination of active ingredients, each with its own potential for drug interactions. It is important to consider these interactions when prescribing or using this medication.

Amantadine HCl, an antiviral and antiparkinsonian agent, may interact with anticholinergic drugs, increasing the risk of side effects such as dry mouth, blurred vision, and urinary retention. It may also interact with CNS stimulants, potentially increasing the risk of seizures.

Amitriptyline HCl, a tricyclic antidepressant, may interact with MAO inhibitors, leading to serious, potentially fatal interactions. It may also interact with anticholinergic drugs, increasing the risk of side effects such as dry mouth, blurred vision, and urinary retention. Additionally, it may interact with CNS depressants, potentially increasing drowsiness and the risk of falls.

Baclofen, a muscle relaxant and antispastic, may interact with other CNS depressants, potentially increasing drowsiness and the risk of falls. It may also interact with antihypertensive drugs, potentially increasing the risk of hypotension.

Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, increasing the risk of bleeding. It may also interact with other NSAIDs, potentially increasing the risk of gastrointestinal bleeding. Additionally, it may interact with antihypertensive drugs, potentially reducing their effectiveness.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids, potentially reducing the absorption of gabapentin. It may also interact with CNS depressants, potentially increasing drowsiness and the risk of falls.

Lidocaine, a local anesthetic, has minimal systemic absorption when applied topically and is unlikely to interact with other medications. However, it may interact with other local anesthetics, potentially increasing the risk of systemic toxicity.

This formulation is designed to treat a variety of disease states, including neuropathic pain, musculoskeletal pain, and certain types of chronic pain. The combination of active ingredients works synergistically to provide pain relief, reduce inflammation, and relax muscles. The topical application allows for targeted treatment, reducing the risk of systemic side effects.

If you have any questions about this formulation or its potential interactions, please do not hesitate to reach out to us. We are here to provide you with the information you need to use this medication safely and effectively.

How Does it Work

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This formulation is a combination of six active ingredients: Amantadine HCl, Amitriptyline HCl, Baclofen, Diclofenac Sodium, Gabapentin, and Lidocaine. Each of these ingredients works in a unique way to provide relief from various disease states.

Amantadine HCl is an antiviral medication that also has properties for treating Parkinson's disease and certain conditions caused by drugs or chemical substances. It works by blocking the actions of certain chemicals in the body that may affect the nervous system.

Amitriptyline HCl is a tricyclic antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression. It is also used to treat symptoms of depression and to prevent migraines, but in this formulation, it is used for its pain-relieving properties.

Baclofen is a muscle relaxer and an antispastic agent. It works by helping to relax the muscles, which can help to reduce pain and discomfort.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause pain and inflammation.

Gabapentin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. In this formulation, it is used for its ability to treat nerve pain.

Lidocaine is a local anesthetic. It works by blocking nerve signals in your body, which helps to numb the area and reduce pain and discomfort.

This formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients are absorbed through the skin and work to provide targeted treatment for the affected area. This can be particularly beneficial for conditions such as neuropathic pain, arthritis, and other conditions that cause pain and inflammation.

It's important to note that while this formulation can provide significant relief from pain and discomfort, it is not a cure for the underlying conditions. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

If you have any questions about this formulation, or if you would like more information about how it works, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Other Uses

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This formulation has potential benefits across a range of medical applications, due to the therapeutic properties observed in each of the active ingredients. Listed below are additional uses for this topical gel, although it is important to consult with your healthcare provider for suitability, dosage and any potential interactions with your current medication regimen.

The active ingredient Amantadine Hydrochloride (HCl) is traditionally used to treat symptoms of parkinson's disease and certain types of influenza, but may also have applications in managing Multiple Sclerosis fatigue, neurologic pain, and even for the management of drug-induced extrapyramidal reactions.

Amitriptyline HCl is a tricyclic antidepressant, often used off-label for pain management, particularly in conditions such as fibromyalgia, postherpetic neuralgia and migraine prophylaxis. It might also be beneficial in aiding the treatment of insomnia, due to its sedative effects.

Baclofen, a muscle relaxer and an antispasmotic agent, is typically prescribed for spasticity in multiple sclerosis. It may also be helpful in conditions such as trigeminal neuralgia, hiccups and even alcohol withdrawal, as some studies suggest.

Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID) known for its potent analgesic, anti-inflammatory and antipyretic properties. While it is mostly used in osteoarthritis and rheumatológic conditions, it might also be incorporated in the treatment of actinic keratosis and acute migraines.

Gabapentin, primarily indicated for epilepsy, may also have uses in neuropathic pain, restless leg syndrome, anxiety disorders, and even hot flashes associated with menopause.

Lidocaine is a local anesthetic that is commonly used in dermatological procedures for its ability to numb the skin. Its benefits extend to temporary relief of itching, burning, and pain from skin inflammations such as poison ivy, poison oak, and poison sumac.

This formulation is powerful and multifunctional, serving a variety of medicinal needs. Patients and prescribers interested in beyond-label use should always monitor closely for any side effects, and report any adverse reactions immediately. As compounding pharmacists, we are always available for any questions or clarifications needed regarding this preparation.

Frequently Asked Questions

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What is this compounded formulation?

This is a compounded medication that contains several active ingredients: Amantadine HCl 8%, Amitriptyline HCl 5%, Baclofen 5%, Diclofenac Sodium 8%, Gabapentin 6%, and Lidocaine 3%. It is presented in a topical gel format for ease of application and targeted treatment.

How do I apply this medication?

This medication comes in a pump mechanism. Simply pump the required dose onto your hand and gently apply it to the affected area on your skin.

What are the advantages of having a gel-like consistency?

Medications in a gel-like consistency are easier to apply, get absorbed quickly, and minimize wastage. They also allow for more precise and targeted application on the desired area.

What purpose does each active ingredient serve?

Each active ingredient plays a role in pain management and inflammation reduction. Amantadine HCl, Amitriptyline HCl, Baclofen, and Gabapentin are generally used to manage nerve pain. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, while Lidocaine is a local anesthetic.

Can this medication be used for all types of pain?

This medication is particularly effective for nerve pain and inflammation. However, always consult your healthcare professional about your specific symptoms and conditions before using it.

How frequently can this medication be used?

Follow the dosage instructions provided by your healthcare professional. They will determine the frequency and amount of the medication based on your symptoms and medical history.

Should this medication be used along with other pain medications?

Always talk to your healthcare professional before starting any new medication, including over-the-counter drugs. They can provide guidance on the safe use of multiple medications.

Will this medication have any side effects?

As with all medications, this gel can have side effects. These can include skin irritation, dryness, or allergy. If any adverse reactions occur, stop using the product and contact your healthcare professional immediately.

Can I use this medication if I'm pregnant or breastfeeding?

If you are pregnant, planning to become pregnant, or breastfeeding, consult with your healthcare professional prior to using this medication. It is important to assess the risks and benefits in such situations.

Is this product safe for children?

Before applying this product on children, please discuss it with your healthcare professional. They consider age, symptoms, and overall health before recommending any medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.