Amantadine Hydrochloride

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Amantadine Hydrochloride is a versatile active pharmaceutical ingredient commonly utilized in compounded formulations for its antiviral and antiparkinsonian properties. It functions by inhibiting viral replication and modulating neurotransmitter activity, making it effective in treating conditions such as influenza and Parkinson's disease.

Its unique mechanism of action involves blocking the M2 protein of the influenza A virus and enhancing dopamine release in the brain, providing symptomatic relief. This API is often chosen for its dual therapeutic benefits, offering prescribers a valuable option in managing diverse patient needs.

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This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.

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Active Ingredient Information

Amantadine Hydrochloride is a versatile active pharmaceutical ingredient widely utilized in various compounded formulations for its antiviral and antiparkinsonian properties. It functions primarily by inhibiting the replication of certain viruses and modulating dopaminergic activity in the central nervous system, making it a valuable component in the management of conditions such as influenza and Parkinson's disease.

In the context of antiviral therapy, Amantadine Hydrochloride is effective against influenza A virus, where it impedes viral uncoating and subsequent replication. This mechanism of action is particularly beneficial during flu outbreaks, providing a therapeutic option for both prophylaxis and treatment. Additionally, its role in Parkinson's disease involves enhancing dopaminergic transmission, which helps alleviate symptoms such as bradykinesia and rigidity.

Amantadine Hydrochloride's pharmacokinetic profile includes oral bioavailability and renal excretion, necessitating dosage adjustments in patients with renal impairment. Its safety and efficacy have been well-documented, although prescribers should be mindful of potential side effects, including dizziness, insomnia, and gastrointestinal disturbances. The compound's multifaceted applications underscore its importance in personalized medicine, where tailored formulations can optimize therapeutic outcomes for individual patients.

Formulas using

Amantadine Hydrochloride

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.