This formulation is a compounded topical gel containing Amantadine HCl 8%, Amitriptyline HCl 4%, Baclofen 2%, Bupivacaine HCl 2%, Clonidine HCl 0.232%, Gabapentin 6%, and Nifedipine 2%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

The combination of these active ingredients is designed to address a variety of disease states. Amantadine is an antiviral medication that also has antiparkinsonian properties, and it can be used to manage symptoms of Parkinson's disease and drug-induced extrapyramidal reactions. Amitriptyline is a tricyclic antidepressant that can help manage neuropathic pain. Baclofen is a muscle relaxant and antispastic agent used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. Bupivacaine is a local anesthetic that provides pain relief. Clonidine is an antihypertensive agent that can also be used off-label for neuropathic pain. Gabapentin is an anticonvulsant and analgesic used to treat seizures and pain caused by shingles. Nifedipine is a calcium channel blocker used to treat high blood pressure and angina.

By combining these medications into a single topical gel, this formulation can provide targeted relief for a variety of symptoms, including pain, muscle stiffness, and high blood pressure. It can be particularly beneficial for patients who have difficulty swallowing pills or who need to avoid systemic side effects of these medications. As with any medication, it's important to use this formulation as directed by a healthcare provider, and to report any side effects or concerns immediately.

If you have any questions about this formulation, or if you're a prescriber interested in using this formulation for your patients, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

This formulation contains a combination of seven active ingredients: Amantadine HCl, Amitriptyline HCl, Baclofen, Bupivacaine HCl, Clonidine HCl, Gabapentin, and Nifedipine. Each of these ingredients has its own potential for drug interactions, which can be increased when used in combination. It's important to note that this formulation is intended for topical use, which may reduce some systemic interactions but does not eliminate the potential entirely.

Amantadine HCl can interact with anticholinergic drugs, causing increased side effects such as dry mouth, blurred vision, and urinary retention. It can also interact with medications that affect the central nervous system, such as sedatives, hypnotics, and tranquilizers, potentially increasing their effects.

Amitriptyline HCl can interact with MAO inhibitors, leading to serious, potentially fatal interactions. It can also interact with anticholinergic drugs, CNS depressants, and other medications that affect serotonin levels, potentially leading to serotonin syndrome.

Baclofen can interact with other central nervous system depressants, including alcohol, antihistamines, and opioids, potentially increasing their effects. It can also interact with medications that affect kidney function, as it is primarily excreted by the kidneys.

Bupivacaine HCl can interact with other local anesthetics and class III antiarrhythmics, potentially leading to additive cardiac effects. It can also interact with medications that affect liver function, as it is primarily metabolized by the liver.

Clonidine HCl can interact with beta-blockers, potentially causing a rebound hypertension if either medication is discontinued abruptly. It can also interact with CNS depressants, potentially increasing their effects.

Gabapentin can interact with antacids, potentially reducing its absorption. It can also interact with opioids, potentially increasing their effects and the risk of respiratory depression.

Nifedipine can interact with beta-blockers, potentially leading to a decrease in blood pressure and heart function. It can also interact with CYP3A4 inhibitors and inducers, potentially affecting its metabolism and efficacy.

This formulation is typically used to treat conditions such as neuropathic pain, muscle spasticity, and certain types of hypertension. The combination of ingredients works to block pain signals, relax muscles, and lower blood pressure. However, due to the potential for drug interactions, it's important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and dietary supplements.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to help ensure that your medication is safe and effective for your needs.

This formulation is a combination of seven active ingredients: Amantadine HCl, Amitriptyline HCl, Baclofen, Bupivacaine HCl, Clonidine HCl, Gabapentin, and Nifedipine. Each of these ingredients works in a unique way to provide relief from various disease states.

Amantadine HCl is an antiviral medication that also has antiparkinsonian properties. It works by blocking the action of certain chemicals in the brain that may contribute to the symptoms of Parkinson's disease. Amitriptyline HCl is a tricyclic antidepressant that increases the levels of certain chemicals in the brain to help improve mood, relieve anxiety, and treat certain types of chronic pain.

Baclofen is a muscle relaxant and an antispastic agent. It works by helping to relax the muscles. Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses in your body to provide pain relief. Clonidine HCl is an antihypertensive that works by relaxing and widening blood vessels, which helps to lower blood pressure.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. Nifedipine is a calcium channel blocker that works by relaxing the muscles of your heart and blood vessels.

When applied topically in a gel form, these active ingredients are absorbed through the skin directly to the area of pain or discomfort. This allows for targeted treatment and can reduce the potential for systemic side effects. The gel is dispensed through a pump mechanism, which allows for easy and precise application.

This formulation can be used to treat a variety of disease states, including neuropathic pain, muscle spasticity, and certain types of chronic pain. It may also be used for other conditions as determined by your healthcare provider.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions about this formulation or how to use it, please reach out to us at Bayview Pharmacy. We're here to help.

Amantadine, Amitriptyline, Baclofen, Bupivacaine, Clonidine, Gabapentin, and Nifedipine together create a potent combination in managing a variety of disorders aside from its main use, compounded into a topical gel for easy and controlled application. It can be repurposed for off-label uses based on its core pharmacological actions.

One of the uses of Baclofen – a muscle relaxant and an antispastic agent - is for the treatment of spasticity. Clonidine, an alpha-agonist hypotensive agent, can be used topically for neuropathic pain. Amitriptyline, besides its antidepression use, can be used for the reduction of chronic nerve-related pain or neuralgia, enabling this compound to be used for retracted pain relief. In combination with Amantadine, an antiviral drug with NMDA antagonist effects, the compound can be used for pain caused by neurological conditions such as multiple sclerosis.

The local anesthetic agent Bupivacaine can be used for temporary relief of pain or pruritus in certain types of eczema or other skin conditions. Nifedipine, a calcium channel blocker, could aid in treating anal fissures, decreasing blood pressure, or treating migraines in some cases. Gabapentin, initially used for seizures, has demonstrated effectiveness in relieving nerve pain and can be used to address neuropathic pain and fibromyalgia.

Potential off-label uses always require a healthcare professional's or a prescriber's examination and approval. As well-informed compounding pharmacists, we caution against the unsupervised use of any medication outside its main indication without professional medical advice. Be aware that side-profiles, potential interactions, and personal allergy history should be considered before any off-label use.

We understand that some conditions may inherently necessitate alternative treatment methods or creative solutions. Please reach out to us with any specific inquiries or if you're interested in exploring additional possibilities offered by this versatile formulation. Our team at Bayview Pharmacy is here to assist and guide you through your inquiries and to aid in the best possible patient outcomes.