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Formulas

Tetracycline HCl 60 mg Oral Capsules

Tetracycline HCl 60 mg Oral Capsules are solid dosage forms consisting of two halves of either gelatin or vegetarian-based shells. These capsules are designed to enclose a precise 60 mg dose of the active ingredient, Tetracycline HCl, which is an antibiotic. The capsule format ensures the medication is easy to swallow and helps to protect the stomach from potential irritation that can be caused by the antibiotic. Tetracycline HCl is used to treat a variety of bacterial infections, including acne, urinary tract infections, intestinal infections, respiratory tract infections, and certain sexually transmitted infections. It is also employed in the treatment of infections caused by chlamydia, rickettsia, and mycoplasma organisms.

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Tetracycline Hydrochloride
Capsules
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Formula Information

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Tetracycline HCl 60 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the medication. This form of medication is designed to be swallowed easily and to ensure that patients receive an accurate dose of the active ingredient, Tetracycline HCl. Tetracycline is a broad-spectrum antibiotic that belongs to the class of medications known as tetracyclines. It works by inhibiting protein synthesis in bacteria, thereby stopping bacterial growth and multiplication. This action makes it effective in treating a variety of bacterial infections.

The 60 mg strength of Tetracycline HCl in these capsules is typically used for the treatment of mild to moderate infections caused by susceptible strains of bacteria. These infections may include acne, urinary tract infections, chlamydia, gonorrhea, and others. It is also used in the treatment of infections such as Rocky Mountain spotted fever, typhus fever, and tick fevers caused by Rickettsiae, as well as respiratory tract infections, skin infections, and infections caused by Mycoplasma pneumoniae.

It is important for prescribers to consider the potential for bacterial resistance when choosing to use tetracycline antibiotics. Tetracycline should only be used to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. Patients should be advised to take the capsules as directed by their healthcare provider, usually on an empty stomach, to maximize absorption. They should also be informed about the potential side effects, which may include gastrointestinal upset, photosensitivity, and, in some cases, effects on dental and bone development in children.

As with any antibiotic, it is crucial for patients to complete the full course of therapy, even if symptoms improve before the medication is finished, to prevent the development of antibiotic-resistant bacteria. Prescribers should also be aware of the contraindications, such as hypersensitivity to tetracycline or other tetracycline antibiotics, and the need for dose adjustments in patients with renal impairment.

If you have any questions or require further information about Tetracycline HCl 60 mg Oral Capsules, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support to both patients and healthcare providers to ensure the safe and effective use of this medication.

Drug Interactions

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Tetracycline HCl is an antibiotic that is used to treat a variety of bacterial infections by inhibiting protein synthesis in bacteria, thereby preventing their growth and multiplication. When considering the use of tetracycline HCl 60 mg oral capsules, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.

One significant interaction is with calcium-containing products, such as dairy products or calcium supplements. Calcium can bind to tetracycline and reduce its absorption, leading to decreased effectiveness. Patients should be advised to take tetracycline at least 2 hours before or 4-6 hours after ingesting calcium-rich foods or supplements. Similarly, antacids containing aluminum, calcium, or magnesium, and iron supplements can also interfere with tetracycline absorption and should be taken separately from the antibiotic.

Concurrent use of tetracycline with other bacteriostatic antibiotics like macrolides or sulfonamides may diminish its therapeutic effects because of the antagonistic effect on bacterial growth inhibition. On the other hand, the use of tetracycline with bactericidal antibiotics such as penicillins may enhance the overall antibacterial action.

Retinoid medications, such as isotretinoin used for acne, may increase the risk of intracranial hypertension when taken with tetracycline. Patients should be monitored for symptoms such as headaches and blurred vision and should inform their healthcare provider if such symptoms occur.

Warfarin and other oral anticoagulants may have their effects potentiated by tetracycline, increasing the risk of bleeding. Patients on anticoagulant therapy should have their prothrombin time or international normalized ratio (INR) monitored closely when initiating or discontinuing tetracycline treatment.

Concomitant use of tetracycline and methoxyflurane anesthesia has been reported to result in fatal renal toxicity, and therefore, this combination should be avoided. Additionally, tetracycline may decrease the efficacy of oral contraceptives, and alternative or additional contraceptive measures should be discussed with patients.

It is also important to note that tetracycline can increase the hepatotoxic effects of other medications, and its use should be carefully considered in patients with liver impairment. Moreover, tetracycline can be nephrotoxic, especially when given in high doses or with other nephrotoxic drugs.

Photosensitivity is a known side effect of tetracycline, and patients should be advised to avoid excessive sunlight or artificial UV light exposure and to use protective measures such as sunscreen or protective clothing when outdoors.

Patients and prescribers should be aware that this is not an exhaustive list of all potential drug interactions with tetracycline. It is essential to review all medications, including over-the-counter drugs and herbal supplements, with a healthcare provider to avoid any potential interactions. If you have any questions or concerns regarding the use of tetracycline HCl 60 mg oral capsules or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Tetracycline HCl, or tetracycline hydrochloride, is an antibiotic that belongs to a class of medications known as tetracyclines. It works by inhibiting the production of proteins that are essential for the growth and reproduction of bacteria. By binding to the 30S ribosomal subunit of the bacterial ribosome, tetracycline HCl prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. This action effectively halts the addition of amino acids to the growing peptide chain, which is necessary for protein synthesis. As a result, the drug impedes the ability of bacteria to multiply and spread, thereby helping the body's immune system to eliminate the bacterial infection.

The 60 mg oral capsule formulation of tetracycline HCl provides a specific dose of the antibiotic, which is critical for achieving the desired therapeutic effect while minimizing the risk of side effects. The solid dosage form consists of two halves of a gelatin or vegetarian-based shell that encapsulate the powdered medication. This design allows for the medication to be released in the digestive system after the capsule is ingested and dissolved. The use of capsules offers several advantages, including ease of swallowing, protection of the medication from the acidic environment of the stomach, and the masking of any unpleasant taste or odor of the active ingredient.

Tetracycline HCl is used to treat a variety of bacterial infections, including but not limited to acne, urinary tract infections, intestinal infections, respiratory tract infections, eye infections, gonorrhea, chlamydia, and others. It is important to note that tetracycline HCl is not effective against viral infections such as the common cold or flu. The precise dosage and duration of treatment with tetracycline HCl capsules will depend on the type and severity of the infection, as well as the patient's overall health and response to the medication.

Patients and prescribers should be aware that tetracycline HCl can interact with certain medications and supplements, including antacids, calcium supplements, iron products, laxatives containing magnesium, and others, which may reduce the absorption and effectiveness of the antibiotic. Additionally, tetracycline HCl can make the skin more sensitive to sunlight, so patients should be advised to use sunscreen and avoid prolonged sun exposure. It is also not recommended for use during pregnancy or in children under the age of 8, as it can affect bone and tooth development.

For more detailed information about the tetracycline HCl 60 mg oral capsules, or if you have any questions regarding this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing the highest level of care and is ready to assist with any inquiries you may have.

Other Uses

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While Tetracycline HCl 60 mg Oral Capsules are primarily prescribed for their antimicrobial properties to treat various infections caused by susceptible strains of bacteria, they have several other off-label applications that may be of interest to patients and prescribers. One such use is in the treatment of acne, particularly when it's moderate to severe and characterized by inflammatory lesions; tetracycline may help reduce the number and severity of acne breakouts. Additionally, tetracycline has been shown to be effective in managing certain atypical infections like Q fever and Lyme disease, where it impedes the growth of the causative organisms.

Another therapeutic application for tetracycline capsules is in the management of periodontal disease, where it aids in reducing the depth of periodontal pockets and inflammation. In some instances, tetracycline can be used as an adjunct therapy in the management of rheumatoid arthritis, revealing its anti-inflammatory properties. Its role in the treatment of ocular infections, such as trachoma and inclusion conjunctivitis, is also notable. It may be used in the prevention of malaria in travelers to regions where the disease is prevalent and resistant to traditional antimalarial drugs, though this is not the first-line treatment.

Furthermore, due to its inhibitory action on protein synthesis, tetracycline has been employed in various experimental research settings, including as a selective agent in molecular biology applications. It must be noted, however, that the usage of tetracycline outside of its approved indications should only be considered when the benefits outweigh the risks and should be done under the guidance of a healthcare professional. Patients or prescribers interested in exploring these alternative uses further should not hesitate to reach out to us for more detailed information and personalized consultation.

Frequently Asked Questions

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What is the purpose of Tetracycline HCl 60 mg Oral Capsules?

Tetracycline HCl 60 mg Oral Capsules are used to treat bacterial infections by inhibiting the growth and reproduction of bacteria. This medication is effective for various types of infections, including respiratory tract infections, skin infections, urinary tract infections, and more.

How should Tetracycline HCl 60 mg Oral Capsules be taken?

These capsules should be taken exactly as prescribed by your healthcare provider. The typical dosage involves taking the capsules with a full glass of water, and it's recommended to take them on an empty stomach, at least one hour before or two hours after a meal.

Are Tetracycline HCl 60 mg Oral Capsules suitable for vegetarians?

These capsules come in both gelatin and vegetarian shell options. If you adhere to a vegetarian diet, be sure to request the vegetarian capsule formulation from your healthcare provider or pharmacist.

What are the benefits of using capsules over other forms of medication?

Capsules offer a convenient and easy-to-swallow option for medication delivery. They also provide a precise dosage of the active ingredients, which is crucial for the effectiveness and safety of the treatment.

Can Tetracycline HCl 60 mg Oral Capsules be opened or split?

It is not recommended to open or split the capsule as this may alter the intended release and absorption of the medication. Always take the capsule whole, unless otherwise directed by your healthcare provider.

What should I do if I miss a dose of Tetracycline HCl 60 mg Oral Capsules?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

Are there any food or drink restrictions while taking Tetracycline HCl 60 mg Oral Capsules?

Yes, you should avoid consuming dairy products, calcium supplements, iron products, laxatives containing magnesium, or antacids shortly before or after taking Tetracycline, as they may interfere with the medication's absorption.

What side effects can I expect from taking Tetracycline HCl 60 mg Oral Capsules?

Common side effects may include nausea, vomiting, diarrhea, loss of appetite, mouth sores, or black hairy tongue. If you experience more severe side effects, such as vision changes, severe headache, or yellowing of the skin/eyes, seek medical attention promptly.

How should I store Tetracycline HCl 60 mg Oral Capsules?

Store the capsules at room temperature away from light and moisture. Do not keep them in the bathroom and keep them out of reach of children and pets.

Can Tetracycline HCl 60 mg Oral Capsules be taken during pregnancy?

Tetracycline can have harmful effects on a fetus and may cause permanent discoloration of the teeth if taken during pregnancy. It is crucial to inform your healthcare provider if you are pregnant, planning to become pregnant, or are breastfeeding before taking this medication.

Can I consume alcohol while taking Tetracycline HCl 60 mg Oral Capsules?

It is generally advised to avoid alcohol consumption while taking antibiotics, including Tetracycline, as it may increase the risk of side effects and can interfere with the efficacy of the medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.