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Formulas

Tetracycline HCl 125 mg Oral Capsules

Tetracycline HCl 125 mg Oral Capsules are solid dosage forms consisting of two halves of either gelatin or vegetarian-based shells. These capsules are designed to enclose a precise 125 mg dose of the active ingredient, Tetracycline HCl, which is an antibiotic. The capsule format ensures the medication is easy to swallow and aids in the accurate delivery of the medication to the body.

This formulation is primarily used in the treatment of various bacterial infections. It is effective against a wide range of disease states, including acne, urinary tract infections, intestinal infections, respiratory tract infections, gonorrhea, chlamydia, and others. Tetracycline works by inhibiting the growth and reproduction of bacteria, thereby treating the infection.

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Tetracycline Hydrochloride
Capsules
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Formula Information

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Tetracycline HCl 125 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the active pharmaceutical ingredient, Tetracycline Hydrochloride, at a strength of 125 milligrams per capsule. This form of medication is designed to be swallowed whole, facilitating ease of administration for the patient while ensuring the delivery of a precise dose of the antibiotic. Tetracycline is a broad-spectrum antibiotic that belongs to the class of tetracyclines, which function by inhibiting protein synthesis in bacteria, thereby stopping bacterial growth and multiplication.

The encapsulated form of Tetracycline HCl is beneficial in treating a variety of bacterial infections, including but not limited to acne, urinary tract infections, intestinal infections, respiratory tract infections, and certain sexually transmitted infections. It is also used in the treatment of infections caused by chlamydia, rickettsia, and mycoplasma organisms. The 125 mg dosage provides a lower dose option, which can be particularly useful in specific populations or when tailored dosing regimens are required.

For prescribers, it is important to note that Tetracycline HCl should be used with caution in patients with renal impairment, and it is contraindicated in children under the age of 8 and in pregnant or breastfeeding women due to the potential for permanent tooth discoloration and other risks. It is also essential to consider potential drug interactions, as tetracycline can interact with other medications such as antacids, calcium supplements, and iron products, which may impair its absorption. Patients should be advised to take the medication on an empty stomach, typically an hour before or two hours after meals, to maximize absorption and efficacy.

As compounding pharmacists at Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the unique needs of each patient. Our Tetracycline HCl 125 mg Oral Capsules are prepared with precision and care, ensuring that each capsule contains the exact amount of medication required for effective treatment. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us. We are here to support both patients and healthcare providers with the information and guidance needed to use this medication safely and effectively.

Drug Interactions

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Tetracycline HCl is an antibiotic that is used to treat a variety of bacterial infections by inhibiting protein synthesis in bacteria, thereby preventing their growth and multiplication. When considering the use of tetracycline HCl 125 mg oral capsules, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.

One significant interaction is with calcium-containing products, including dairy products and calcium supplements. Calcium can bind to tetracycline and reduce its absorption, leading to decreased effectiveness. Patients should be advised to take tetracycline at least 2 hours before or 4-6 hours after ingesting calcium-rich foods or supplements.

Similarly, antacids containing aluminum, calcium, or magnesium, and iron supplements can also interfere with tetracycline absorption. The same time separation as with calcium-containing products should be applied when taking these agents. Multivitamins with minerals should also be taken at a different time than tetracycline.

Concurrent use of tetracycline with other potentially nephrotoxic or hepatotoxic medications may increase the risk of kidney or liver damage. Careful monitoring is advised when tetracycline is prescribed with such medications. Additionally, tetracycline can enhance the anticoagulant effect of warfarin and other oral anticoagulants, which may necessitate a dosage adjustment and close monitoring of prothrombin time or INR.

Retinoid medications, such as isotretinoin or acitretin, taken concurrently with tetracycline, may increase the risk of intracranial hypertension. Patients should be monitored for signs and symptoms of this condition, such as headache, blurred vision, and dizziness.

Barbiturates, carbamazepine, and phenytoin may decrease the half-life of tetracycline, leading to reduced efficacy. Conversely, tetracycline can reduce the clearance of methotrexate, potentially leading to increased toxicity. Patients on methotrexate therapy should be closely monitored for adverse effects if tetracycline is prescribed.

It is also important to note that tetracycline can reduce the effectiveness of oral contraceptives. Patients should be advised to use an additional or alternative method of contraception while taking tetracycline.

Lastly, the concurrent use of tetracycline and penicillin should be avoided as they are antagonistic, and their simultaneous use may reduce the efficacy of penicillin.

Patients and prescribers should be aware that this is not an exhaustive list of all potential drug interactions. It is important to disclose all medications, supplements, and over-the-counter products the patient is taking to the pharmacist or healthcare provider to ensure safe and effective use of tetracycline HCl oral capsules. If you have any questions or concerns regarding drug interactions with tetracycline HCl, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Tetracycline HCl, or tetracycline hydrochloride, is an antibiotic that belongs to a class of medications known as tetracyclines. It works by inhibiting the production of proteins that are essential for the growth and reproduction of bacteria. By binding to the 30S ribosomal subunit of the bacterial ribosome, tetracycline HCl prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. This action effectively halts the addition of amino acids to the growing peptide chain, thereby stopping protein synthesis. Without these proteins, bacteria cannot perform vital functions, replicate, or spread, leading to the elimination of the bacterial infection.

The 125 mg oral capsule formulation of tetracycline HCl provides a convenient and precise dosage form. The medication is encapsulated within two halves of a gelatin or vegetarian shell, which are then sealed together. These capsules are designed to be swallowed whole with water, and upon reaching the stomach, the shell dissolves, releasing the tetracycline HCl for absorption into the bloodstream. The solid dosage form ensures that the medication is delivered in a controlled manner, reducing the risk of degradation by stomach acid and enzymes, which can sometimes occur with liquid formulations.

Tetracycline HCl is effective against a wide range of gram-positive and gram-negative bacteria, making it useful in treating various infections such as acne, urinary tract infections, intestinal infections, respiratory tract infections, and certain sexually transmitted infections. It is also used in the treatment of infections caused by chlamydiae, rickettsiae, and certain types of mycoplasmas. However, it is important to note that tetracycline HCl is not effective against viral infections such as the common cold or flu.

For patients and prescribers considering the use of tetracycline HCl 125 mg oral capsules, it is essential to be aware of potential side effects, drug interactions, and contraindications. For example, tetracycline HCl should not be used during pregnancy or in children under the age of eight due to the risk of permanent tooth discoloration. Additionally, it should be taken on an empty stomach to maximize absorption, and patients should avoid taking it with dairy products or antacids, which can interfere with its effectiveness.

If you have any questions about the tetracycline HCl 125 mg oral capsules or how they work in treating specific bacterial infections, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure safe and effective treatment.

Other Uses

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Tetracycline HCl, traditionally known for its antibacterial properties, can also have uses beyond its primary indication for treating infections. While this formulation of tetracycline HCl 125 mg oral capsules is specifically designed to fight a range of bacterial diseases, patients and prescribers may find that it has additional off-label applications. For example, tetracycline has been observed to reduce the severity of acne by inhibiting the growth of acne-causing bacteria and reducing inflammation. Furthermore, it may be prescribed as an adjunct therapy in treating certain gastrointestinal disorders caused by Helicobacter pylori, a bacterium known to lead to ulcers. It's important to note that the anti-inflammatory properties of tetracycline can also make it useful in managing chronic inflammatory conditions such as rosacea, providing relief for the skin redness and pimples associated with this disorder.

Also noteworthy is the role of tetracycline in the management of periodontal disease. The antibiotic's ability to target the bacteria that contribute to gum disease can help to slow the progression of this condition, particularly when coupled with proper dental hygiene. In some cases, tetracycline is also used in the treatment of certain protozoal infections and some non-infective conditions where its inhibition of protein synthesis in cells can be beneficial. It is crucial for prescribers to balance the potential benefits of off-label uses with the risks, considering factors such as antibiotic resistance and the individual patient’s medical history. Additionally, tetracycline can interfere with the effectiveness of oral contraceptives and should be used with caution in patients relying on these forms of birth control.

Patients and prescribers should be aware that tetracycline use is contraindicated in pregnant women, nursing mothers, and children under the age of eight due to the potential for permanent tooth discoloration and effects on bone growth in the fetus or child. As with any medication, the potential for side effects and drug interactions exists, and these should be discussed with a healthcare professional. If you have any questions or need more information about the wide range of applications for tetracycline HCl 125 mg oral capsules or if you have specific concerns regarding its use, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is dedicated to providing thorough and personalized information to ensure the safe and effective use of this medication in its various applications.

Frequently Asked Questions

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What is Tetracycline HCl 125 mg Oral Capsule?

Tetracycline HCl 125 mg Oral Capsule is a solid dosage form of medication containing 125 milligrams of Tetracycline Hydrochloride as the active ingredient. It is used to treat various bacterial infections. These capsules are composed of two halves that form a shell, typically made of gelatin or vegetarian material, which encloses the medication.

How should I take Tetracycline HCl 125 mg Oral Capsules?

Take Tetracycline HCl 125 mg Oral Capsules exactly as prescribed by your doctor. It is usually taken on an empty stomach, one hour before or two hours after meals. Swallow the capsule whole with a full glass of water to avoid irritating the throat or stomach.

Can I open the capsule and mix the contents with food?

No, you should not open the capsule and mix the contents with food. The Tetracycline HCl 125 mg Oral Capsule should be taken whole to ensure you receive the correct dosage of the medication as designed.

Are Tetracycline HCl 125 mg Oral Capsules suitable for vegetarians?

The suitability of Tetracycline HCl 125 mg Oral Capsules for vegetarians depends on the composition of the shell. If the shell is made from vegetarian material, then it is suitable for vegetarians. Check the label for this information or consult your pharmacist or healthcare provider.

What should I do if I miss a dose of Tetracycline HCl 125 mg Oral Capsules?

If you miss a dose of Tetracycline HCl 125 mg Oral Capsules, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Can I take Tetracycline HCl 125 mg Oral Capsules with dairy products?

Tetracycline HCl 125 mg Oral Capsules should not be taken with dairy products or calcium-fortified juices. These products can interact with tetracycline, making it less effective. Take the capsule at least one hour before or two hours after consuming such products.

What are the possible side effects of Tetracycline HCl 125 mg Oral Capsules?

Side effects of Tetracycline HCl 125 mg Oral Capsules may include nausea, vomiting, diarrhea, and upset stomach. If you experience severe side effects such as difficulty breathing, skin rash, or yellowing of the skin or eyes, contact your doctor immediately.

How should I store Tetracycline HCl 125 mg Oral Capsules?

Store Tetracycline HCl 125 mg Oral Capsules at room temperature, away from direct light, heat, and moisture. Keep the capsules in their original container, and ensure the lid is tightly closed to protect the medication from moisture and to keep it safe from children and pets.

Can I take Tetracycline HCl 125 mg Oral Capsules if I am pregnant or breastfeeding?

Tetracycline HCl 125 mg Oral Capsules are not recommended during pregnancy or breastfeeding. Tetracycline can harm the fetus and may affect bone and tooth development in the baby. If you are pregnant, planning to become pregnant, or breastfeeding, discuss alternative treatments with your healthcare provider.

Do I need a prescription to buy Tetracycline HCl 125 mg Oral Capsules?

Yes, you need a prescription from a healthcare provider to buy Tetracycline HCl 125 mg Oral Capsules. This medication should be used under the guidance of a doctor to ensure safe and appropriate treatment of your condition.

Can I take other medications along with Tetracycline HCl 125 mg Oral Capsules?

Some medications may interact with Tetracycline HCl 125 mg Oral Capsules, potentially decreasing its effectiveness or increasing the risk of side effects. Always inform your healthcare provider of all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid drug interactions.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.