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Formulas

Potassium Iodide 130 mg Oral Capsules

Potassium Iodide 130 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the active ingredient. This design ensures the medication is easy to swallow and delivers a precise dose of potassium iodide to the patient. Potassium iodide is commonly used in the prevention of thyroid damage following radiation exposure and in the treatment of hyperthyroidism. Additionally, it is utilized in emergency situations for thyroid protection in the event of a nuclear accident. These capsules provide a convenient and accurate way to administer the necessary medication for these specific disease states.

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Potassium Iodide
Capsules
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Formula Information

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Potassium Iodide 130 mg Oral Capsules are a solid dosage form consisting of two halves of either gelatin or vegetarian-based shells that encapsulate the active ingredient, potassium iodide. This form of medication delivery is designed to be easily swallowed and ensures that patients receive an exact dose of the active compound. Potassium iodide is a stable iodine salt, which is crucial in the prevention and treatment of various conditions related to iodine deficiency and thyroid function.

In the context of thyroid health, potassium iodide is often used in emergency situations to protect the thyroid gland from the uptake of radioactive iodine, which can be released during nuclear accidents. By saturating the thyroid with stable iodine, potassium iodide capsules can reduce the risk of thyroid cancer, especially in children and adolescents who are most susceptible. Additionally, potassium iodide is used in the management of hyperthyroidism, as it can help to reduce thyroid hormone levels and decrease the gland's activity.

Another application of potassium iodide is in the treatment of cutaneous sporotrichosis, a fungal infection of the skin. Potassium iodide helps to eliminate the fungus from the body, promoting healing of the lesions. It is also used in the treatment of fibrocystic breast disease, where it can alleviate the symptoms associated with the condition, such as breast pain and tenderness.

It is important for both patients and prescribers to be aware that potassium iodide should be used under medical supervision, as incorrect use can lead to side effects such as gastrointestinal upset, allergic reactions, or thyroid dysfunction. The precise dosing and encapsulation of potassium iodide in the 130 mg oral capsule form help to mitigate the risk of dosing errors and enhance patient compliance.

For any questions or additional information regarding Potassium Iodide 130 mg Oral Capsules, including their use, contraindications, and potential interactions with other medications, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to ensure the safe and effective use of this medication.

Drug Interactions

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Potassium iodide (KI) is an inorganic compound that is often used in the prophylaxis of thyroid cancer by saturating the thyroid gland with iodine, thereby preventing the uptake of radioactive iodine isotopes. It is also used in the treatment of hyperthyroidism and to protect against radiation exposure. When considering the use of potassium iodide 130 mg oral capsules, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.

One significant interaction is with lithium, a medication used to treat bipolar disorder. Concurrent use of potassium iodide with lithium may increase the risk of hypothyroidism and goiter. Patients on lithium therapy should be closely monitored for thyroid function if they are prescribed potassium iodide. Additionally, medications that reduce thyroid hormone production, such as methimazole or propylthiouracil, may have additive effects when used with potassium iodide, potentially leading to hypothyroidism.

Diuretics, especially those that are potassium-sparing such as spironolactone, triamterene, or amiloride, can increase the risk of hyperkalemia when used with potassium iodide. It is important to monitor serum potassium levels and renal function in patients taking both potassium iodide and potassium-sparing diuretics. Conversely, loop and thiazide diuretics may increase the renal excretion of iodide, potentially reducing the effectiveness of potassium iodide.

Antithyroid agents, including potassium iodide, may interact with anticoagulants like warfarin. Potassium iodide can alter thyroid function, which may change the metabolism of warfarin and affect its anticoagulant activity. Patients on warfarin should have their coagulation status closely monitored and dosage adjustments may be necessary.

Patients taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) should be cautious when using potassium iodide, as these medications can also increase serum potassium levels, leading to an increased risk of hyperkalemia. Regular monitoring of potassium levels is recommended for patients on these medications.

High doses of potassium iodide can also interact with foods containing goitrogens, substances that can interfere with thyroid hormone synthesis. Foods such as soybeans, cabbage, broccoli, and cauliflower may reduce the efficacy of potassium iodide when consumed in large quantities.

It is also important to note that potassium iodide can cause adverse reactions in individuals with a history of iodine hypersensitivity, dermatitis herpetiformis, or hypocomplementemic vasculitis. These patients should avoid using potassium iodide unless specifically directed by a healthcare provider.

Given the potential for drug interactions and adverse effects, prescribers and patients should review all current medications, including over-the-counter drugs and dietary supplements, before initiating treatment with potassium iodide. Regular monitoring of thyroid function, renal function, and serum electrolytes is recommended to ensure safe and effective use of this medication. If you have any questions or concerns regarding the use of potassium iodide 130 mg oral capsules or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Potassium Iodide (KI) 130 mg oral capsules are a solid dosage form that consists of two halves of a gelatin or vegetarian-based shell, which are filled with the precise amount of potassium iodide and then sealed together. This form of encapsulation ensures that the active ingredient is delivered in a specific dose, which is essential for the efficacy and safety of the medication. The capsules are designed to be swallowed whole with water, making them a convenient option for patients.

The primary mechanism by which potassium iodide works is by saturating the thyroid gland with non-radioactive iodine. When the thyroid gland has absorbed enough iodine, it will not take in radioactive iodine, which can be present in the environment following certain types of nuclear events. This is why potassium iodide is often used as a protective measure in radiation emergencies to prevent radioactive iodine from entering the thyroid gland, thereby reducing the risk of thyroid cancer.

In addition to its use in radiation emergencies, potassium iodide has therapeutic applications in the treatment of hyperthyroidism and certain skin conditions. In hyperthyroidism, potassium iodide can help to reduce the thyroid gland's overproduction of thyroid hormones. For dermatological conditions, such as sporotrichosis, a fungal infection, potassium iodide helps to clear the infection by an unknown mechanism, possibly through its anti-inflammatory or immunomodulatory effects.

It is important for both patients and prescribers to understand that while potassium iodide can be very effective in these disease states, it should be used with caution. Overuse or inappropriate use can lead to iodine toxicity or can interfere with thyroid function. Therefore, it is essential to follow the prescribed dosage and to be aware of potential side effects, which may include gastrointestinal upset, allergic reactions, or alterations in thyroid function tests.

For those considering the use of potassium iodide 130 mg oral capsules, it is crucial to consult with a healthcare professional to ensure that it is appropriate for your specific condition and to understand the proper usage. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the knowledge and support you need to make informed decisions about your health and medication needs.

Other Uses

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Potassium Iodide 130 mg Oral Capsules, typically encapsulated in convenient solid dosage forms such as two-piece gelatin or vegetarian capsules, are most commonly indicated for certain specific medical uses, including the prevention of thyroid damage in the event of exposure to radioactive iodine due to nuclear accidents or emergencies. It functions by saturating the thyroid gland with stable iodine, thereby reducing the uptake of the radioactive molecules.

Aside from this well-known application, Potassium Iodide capsules can have other, less widely recognized uses. They have been employed in the management of hyperthyroidism as an adjuvant therapy because of their capacity to inhibit the synthesis and release of thyroid hormones. For similar reasons, they are sometimes used preoperatively in thyroidectomy procedures to reduce the vascularity of the thyroid gland and the associated risk of hemorrhage. Additionally, Potassium Iodide has been utilized as an expectorant to thin mucus secretions in the treatment of chronic pulmonary diseases, helping in loosening and easier clearance of mucous from the airways.

Another therapeutic application of Potassium Iodide is in the treatment of certain dermatological conditions, such as sporotrichosis, a fungal infection of the skin. It is also used off-label for its anti-inflammatory and immunomodulatory effects in the treatment of nodular and infiltrative dermal conditions, although these uses are less common and may not be as extensively studied.

It is important for both patients and prescribers to note that the use of Potassium Iodide, especially for other than its main indications, should be approached with caution and under the guidance of medical professionals. Because the range of non-emergency uses of Potassium Iodide is less well-known, they should be chosen based on individual patient needs and after a careful evaluation of the potential risks and benefits. Moreover, Potassium Iodide can interact with various medications and underlying health conditions, thereby necessitating careful monitoring by healthcare providers.

For anyone considering Potassium Iodide 130 mg Oral Capsules for uses beyond the primary indications, it is advised that you engage in a detailed discussion with healthcare professionals to ascertain its suitability for your specific condition. If you have any questions regarding the potential uses of this medication or if you need additional information on its applications, do not hesitate to reach out to us for guidance and expertise.

Frequently Asked Questions

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What is the purpose of Potassium Iodide 130 mg Oral Capsules?

Potassium Iodide 130 mg Oral Capsules are typically used to protect the thyroid gland against the effects of radiation by blocking the absorption of radioactive iodine. It can also be used for other thyroid-related issues as prescribed by a healthcare professional.

How should Potassium Iodide 130 mg Oral Capsules be taken?

The capsules should be taken orally with a full glass of water and can be taken with or without food. Follow your doctor's instructions regarding the dosage and timing of the medication. Do not chew or open the capsules.

Are Potassium Iodide 130 mg Oral Capsules safe for everyone?

While safe for most people when taken as directed, some individuals with allergies to iodine, dermatitis herpetiformis, or hypocomplementemic vasculitis should not take this medication. Patients with thyroid disorders should consult a healthcare professional before use.

What are the possible side effects of taking Potassium Iodide 130 mg Oral Capsules?

Common side effects may include gastrointestinal upset, hypersensitivity reactions, and iodism (chronic poisoning by iodine or its compounds). If you experience any severe reactions or signs of an allergic reaction, seek immediate medical attention.

Can I take Potassium Iodide 130 mg Oral Capsules during pregnancy?

Pregnant women should only take Potassium Iodide 130 mg Oral Capsules if clearly needed and directed by a healthcare professional due to potential risks to the developing fetus. Always consult with your doctor before taking any medication during pregnancy.

How should I store Potassium Iodide 130 mg Oral Capsules?

Store the capsules in a cool, dry place away from light and moisture. Keep the medication out of reach of children and pets.

Can I take Potassium Iodide 130 mg Oral Capsules with other medications?

It is important to inform your healthcare provider of all the medications you are currently taking, as Potassium Iodide 130 mg Oral Capsules can interact with certain drugs. Your doctor will advise you on the safety of combining this medication with others.

What if I miss a dose of Potassium Iodide 130 mg Oral Capsules?

If you miss a dose, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What is the shelf life of Potassium Iodide 130 mg Oral Capsules?

The shelf life of Potassium Iodide 130 mg Oral Capsules varies by manufacturer and should be checked on the packaging. Do not use beyond the expiration date marked on the bottle.

Are there any dietary restrictions while taking Potassium Iodide 130 mg Oral Capsules?

Generally, there are no specific dietary restrictions while taking this medication, but it is advisable to follow any guidelines provided by your healthcare provider. Excessive consumption of foods high in iodine may affect the efficacy of the medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.