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Formulas

Phenazopyridine HCl 200 mg/5 mL Oral Liquid

The Phenazopyridine HCl 200 mg/5 mL Oral Liquid is a specially compounded medication designed for oral use. This formulation offers a precise and convenient method for administering the active ingredient, phenazopyridine, which is commonly used to provide symptomatic relief from pain, irritation, and discomfort associated with urinary tract infections (UTIs). The liquid dosage form is particularly beneficial for patients who experience difficulty swallowing pills, such as children and the elderly. By alleviating the discomfort of UTIs, this medication aids in improving the quality of life for affected individuals during the course of their treatment.

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Phenazopyridine Hydrochloride
Oral Liquid
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Formula Information

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Phenazopyridine HCl 200 mg/5 mL Oral Liquid is a specially compounded medication designed for ease of administration and accurate dosing. This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who prefer a liquid dosage form. Phenazopyridine HCl, the active ingredient, is commonly used to relieve the symptoms associated with urinary tract infections (UTIs), such as pain, burning, urgency, and frequency of urination. It functions as a urinary tract analgesic, providing symptomatic relief by targeting the lining of the urinary tract to alleviate discomfort.

The 200 mg/5 mL concentration allows for precise dosing tailored to the patient's needs, ensuring that the therapeutic effects are achieved with minimal risk of overdose or underdosing. It is important to note that while phenazopyridine provides symptomatic relief, it does not treat the underlying infection; therefore, it is often used in conjunction with an appropriate antibiotic therapy prescribed by a healthcare provider. Patients should be advised that phenazopyridine can cause a harmless red-orange discoloration of the urine and may stain fabric. It is also essential to instruct patients to adhere to the prescribed dosage and duration of therapy to avoid potential adverse effects.

For prescribers considering this formulation, it is crucial to assess the patient's medical history, current medications, and potential for drug interactions. Phenazopyridine should be used with caution in patients with renal impairment, as the drug is primarily excreted by the kidneys. Monitoring for signs of overdose, such as skin discoloration or gastrointestinal disturbances, is also recommended. As compounding pharmacists at Bayview Pharmacy, we ensure that each batch of Phenazopyridine HCl 200 mg/5 mL Oral Liquid is prepared to the highest standards of quality and consistency, providing a reliable and effective option for symptomatic relief of UTI symptoms.

If you have any questions regarding this formulation or its use, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists is here to provide guidance and support to both patients and healthcare providers to ensure optimal therapeutic outcomes.

Drug Interactions

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Phenazopyridine HCl is a urinary tract analgesic used for the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. The exact mechanism of action is not well understood, but it is believed to provide a local analgesic effect on the mucosa of the urinary tract. It is important to note that phenazopyridine does not treat the cause of urinary discomfort, such as infection, and should only be used in conjunction with an appropriate antimicrobial agent if an infection is present.

When considering the use of phenazopyridine HCl 200 mg/5 mL oral liquid, it is crucial to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects. Phenazopyridine is primarily metabolized in the liver and excreted by the kidneys, so caution should be exercised when used concurrently with other medications that may alter liver enzyme activity or renal function.

Concomitant use of phenazopyridine with renal function-altering agents such as NSAIDs, ACE inhibitors, or diuretics may increase the risk of renal impairment and should be monitored closely. Additionally, the use of phenazopyridine with other potentially hepatotoxic drugs like acetaminophen or isoniazid may increase the risk of liver injury. Patients should be advised to avoid excessive alcohol consumption while taking phenazopyridine, as this may exacerbate liver metabolism stress.

Phenazopyridine may also interfere with laboratory tests, including urine glucose tests and urine ketone tests, leading to false test results. It is important to inform healthcare providers and laboratory personnel that you are taking this medication before undergoing any tests. The medication can cause a red-orange discoloration of the urine, which is not harmful but can stain clothing or fabric.

Patients on anticoagulant therapy, such as warfarin, should use phenazopyridine with caution, as there have been reports of altered prothrombin time or bleeding in patients on concurrent anticoagulant therapy. Regular monitoring of prothrombin time or INR is recommended in these cases.

It is also advisable to avoid concurrent use of phenazopyridine with other central nervous system depressants, as additive sedative effects may occur. This includes medications such as benzodiazepines, opioids, and certain antihistamines.

As with any medication, it is important to inform your healthcare provider of all prescription, over-the-counter medications, herbal supplements, and vitamins you are taking to avoid potential interactions. If you experience any unusual symptoms or side effects while taking phenazopyridine HCl oral liquid, contact your healthcare provider immediately. For any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for professional advice and guidance.

How Does it Work

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Phenazopyridine HCl, the active ingredient in this oral liquid formulation, is a urinary tract analgesic. When ingested, it exerts its effect directly on the mucosa of the urinary tract to provide symptomatic relief from pain, burning, urgency, frequency, and other discomforts that may arise from irritation of the lower urinary tract. These symptoms are often associated with conditions such as urinary tract infections (UTIs), trauma, surgery, or the insertion of catheters or other instruments. Phenazopyridine HCl does not possess antibacterial properties; therefore, it does not cure infections but rather provides temporary relief from their symptoms.

The mechanism by which phenazopyridine HCl provides relief is not fully understood, but it is believed to serve as a local analgesic. It is thought to work by exerting a topical analgesic effect on the mucosa of the urinary tract, thereby diminishing the sensation of pain. After oral administration, phenazopyridine is rapidly absorbed and then excreted in the urine, where it exerts its pain-relieving effects. The specific formulation of 200 mg/5 mL allows for precise dosing, which can be adjusted according to the severity of the symptoms and the needs of the patient.

This liquid formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who may have an impaired gag reflex or dysphagia. The liquid form allows for easier swallowing and can be measured to provide the exact dose required. Additionally, the liquid formulation allows for a faster onset of action compared to solid dosage forms, as the medication does not need to be broken down in the stomach before absorption.

It is important to note that while phenazopyridine HCl provides symptomatic relief, it should be used in conjunction with an appropriate antibacterial agent if a bacterial infection is present. Treatment duration with phenazopyridine HCl should not exceed two days without consulting a healthcare provider, as longer use may mask symptoms. Patients should also be advised that phenazopyridine HCl can cause a red-orange discoloration of the urine and may stain fabric. This is a harmless side effect but can be alarming if unexpected.

For prescribers and patients interested in using this phenazopyridine HCl 200 mg/5 mL oral liquid formulation, it is essential to consider the patient's overall health status, including kidney function, as the drug is primarily eliminated by the kidneys. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is ready to assist you with your medication needs and provide additional guidance on the appropriate use of this medication.

Other Uses

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Phenazopyridine HCl, typically prescribed for its analgesic properties to relieve symptoms associated with urinary tract infections (UTIs), such as burning, pain, and discomfort during urination, may also serve alternative therapeutic roles. Although not its primary indication, there has been some exploration into its utility in providing symptomatic relief for other minor irritations of the lower urinary tract caused by surgery, injury, or examination procedures such as catheterization, cystoscopy, or endoscopy. Its mode of action is not anti-infective, but its analgesic effects can aid in overall patient comfort during recovery from these types of procedures.

Patients with conditions that affect the bladder and cause frequent urination or dysuria may find some symptomatic relief with the use of phenazopyridine HCl oral solution as an adjunct therapy. However, its effectiveness for indications other than those associated with UTIs has not been established in controlled clinical trials, and therefore, its use for other conditions should be considered carefully and on a case-by-case basis. Additionally, clinicians should be aware that this compound can interfere with diagnostic tests that analyze urine color or components and should ensure patients discontinue use prior to these tests.

In cases where the oral solid form of medication is impractical, such as with patients who have difficulty swallowing pills, neurodegenerative diseases like Parkinson's, or in pediatrics and geriatrics, this liquid formulation can be particularly valuable. Furthermore, this liquid form allows for dose titration, which may be beneficial for special populations, such as individuals with renal impairment, where dosing requirements need to be adjusted cautiously.

Given the potential for adverse effects associated with phenazopyridine use, such as reddish-orange discoloration of the urine, gastrointestinal upset, or hypersensitivity reactions, it is important for prescribers to weigh the benefits against the risks before prescribing this medication for off-label uses. As always, our knowledgeable compounding pharmacists are here to provide guidance and information regarding the safe and effective use of phenazopyridine HCl 200 mg/5 mL oral liquid. Patients and prescribers with questions or concerns about the use of this medication for alternative indications are encouraged to reach out to us at Bayview Pharmacy for personalized support and consultation.

Frequently Asked Questions

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What is Phenazopyridine HCl Oral Liquid used for?

Phenazopyridine HCl Oral Liquid is used to alleviate the pain, burning, urgency, frequency, and other discomforts caused by irritation of the lower urinary tract mucosa due to infection, surgery, endoscopic procedures, or the passage of sounds or catheters.

How should Phenazopyridine HCl Oral Liquid be taken?

Take this medication by mouth, usually three times a day after meals or as directed by your healthcare provider. The dosing may vary based on your medical condition and response to treatment, so follow your prescriber's specific instructions.

What are the benefits of using the liquid form of Phenazopyridine HCl?

The liquid form of Phenazopyridine provides a convenient alternative for those who have difficulty swallowing pills, such as children and the elderly, and allows for accurate dosing tailored to the patient's specific needs.

Are there any special storage conditions for Phenazopyridine HCl Oral Liquid?

This medication should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep the bottle tightly closed and out of reach of children and pets.

Can there be side effects when taking Phenazopyridine HCl Oral Liquid?

Yes, side effects can occur with any medication. Common side effects include headache, dizziness, and stomach upset. If you experience any severe side effects, such as yellowing skin/eyes or severe urinary problems, contact your healthcare provider immediately.

Can Phenazopyridine HCl Oral Liquid discolor urine?

Yes, Phenazopyridine HCl Oral Liquid may cause a red-orange discoloration of the urine. This is not harmful, but it can stain clothing or fabric.

Is Phenazopyridine HCl Oral Liquid suitable for children?

Phenazopyridine HCl Oral Liquid can be suitable for children, as the liquid form allows flexibility for accurate dosing. However, it should be used in children only under the guidance of a healthcare provider.

How quickly does Phenazopyridine HCl Oral Liquid start to work?

Phenazopyridine HCl typically begins to relieve symptoms within 24 hours after taking the medication. However, it varies among individuals. If you don't notice improvement, contact your healthcare provider.

Can I take Phenazopyridine HCl Oral Liquid with other medications?

Some drugs may interact with Phenazopyridine HCl Oral Liquid. Inform your healthcare provider of all other medications you are taking to prevent potential interactions.

What should I do if I miss a dose of Phenazopyridine HCl Oral Liquid?

If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Is Phenazopyridine HCl Oral Liquid a cure for urinary tract infections (UTIs)?

No, Phenazopyridine HCl Oral Liquid is used to relieve symptoms of a UTI, but it does not treat the actual infection. Antibiotics are typically needed to treat a UTI.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.