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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository

The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication. This solid dosage form is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication. It is used for the treatment of chronic pain, nausea, vomiting, gastroparesis, and dyspepsia, providing local or systemic absorption.

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Formula Information

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The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication that combines two active ingredients to provide relief from pain and nausea. Morphine Sulfate, an opioid analgesic, works by blocking pain signals from reaching the brain. Metoclopramide, a dopamine antagonist, aids in reducing nausea and vomiting. This combination suppository is an effective treatment for a variety of conditions, including postoperative pain, cancer pain, and nausea associated with chemotherapy.

This suppository is a solid dosage form that is inserted into a body cavity, typically the rectum, where it dissolves or melts to release the medication for local or systemic absorption. It is easy to administer and provides fast-acting relief. The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is available in various strengths and can be used in both adults and children. The dosage should be adjusted according to the patient's individual needs.

It is important to note that this medication should not be used for more than five consecutive days. Additionally, it should not be used in combination with other opioid medications due to the risk of potential interactions. Always consult with a healthcare professional before starting any new medication regimen.

If you have any questions about the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository or how it can be used to treat your condition, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to help you find the best treatment option for your needs.

Drug Interactions

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded formulation designed for the management of nausea and vomiting symptoms often associated with chemotherapy, radiation therapy, and postoperative recovery. The suppository is a solid dosage form that is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

The medication combines the effects of Morphine Sulfate, an opioid agonist that acts on the central nervous system to alleviate pain, and Metoclopramide, a dopamine antagonist that enhances gastric motility and reduces nausea and vomiting. The combination of these two medications in a suppository form offers a more effective and longer-lasting relief of nausea and vomiting than either medication alone.

Patients should be aware that this medication may cause side effects such as drowsiness, dizziness, and confusion. It is advised not to drive or operate machinery until the effects of the medication are fully understood. This medication may also cause constipation, hence it is recommended to maintain adequate hydration and a high-fiber diet. Additionally, this medication may cause an increase in blood pressure, thus regular monitoring is advised.

It is important to note that this medication may interact with other medications, including anticholinergics, antihistamines, and other opioids. Patients should inform their healthcare provider of all medications they are currently taking before using this medication.

Healthcare providers should exercise caution when prescribing this medication to patients with a history of substance abuse or mental illness due to the potential side effects of drowsiness, dizziness, and confusion. Regular monitoring of the patient's blood pressure is also recommended due to the potential for increased blood pressure.

If you have any questions about this medication or its interactions, please do not hesitate to reach out for further information.

How Does it Work

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication designed to alleviate moderate to severe pain, as well as nausea and vomiting. This combination medication works by utilizing the pain-blocking properties of morphine sulfate, which prevents pain signals from reaching the brain, and the action of metoclopramide, which blocks certain chemicals in the body to reduce nausea and vomiting.

The suppository is administered rectally, where it dissolves or melts to release the medication. The active ingredients are then absorbed into the bloodstream through the walls of the rectum. For optimal results, the suppository should be inserted into the rectum and left in place for at least 15 minutes before being removed.

When using Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository, it is crucial to adhere to the instructions provided by your healthcare provider or pharmacist. This medication should not be used for more than 5 consecutive days due to the risk of serious side effects. If you experience any adverse reactions, such as dizziness, drowsiness, or confusion, it is important to contact your healthcare provider or pharmacist immediately.

If you have any questions or concerns about Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository, or any other medication, please do not hesitate to reach out to us at Bayview Pharmacy. Our team is dedicated to providing you with the information you need to make informed decisions about your health and medications.

Other Uses

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded formulation that serves multiple therapeutic purposes. It is primarily used for the management of severe pain, but it also has other potential uses. This formulation can be used to treat abdominal pain, constipation, and diarrhea. It may also be beneficial in reducing the severity of opioid withdrawal symptoms, providing relief to those undergoing treatment for opioid addiction.

Another significant use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is in the prevention of aspiration in patients with impaired gastric emptying. This can be particularly useful in patients with certain gastrointestinal disorders or those undergoing specific medical procedures. Furthermore, it can be used to mitigate the risk of postoperative nausea and vomiting, a common side effect experienced by many patients after surgery.

Postoperative ileus, a condition characterized by a temporary loss of bowel function after surgery, can also be managed with this formulation. It may also be used to reduce the risk of postoperative pain, providing comfort and facilitating recovery. Additionally, it can be used to prevent postoperative urinary retention and constipation, further enhancing patient comfort and recovery.

Another potential use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is in the prevention of postoperative respiratory depression, a serious complication that can occur after surgery. This formulation can help ensure the safety and well-being of patients during their postoperative period.

If you have any questions about the use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository for any of these conditions, please do not hesitate to reach out for more information.

Frequently Asked Questions

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What is the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository?

This is a compounded formulation of two medications, Morphine Sulfate and Metoclopramide, in a solid dosage form that is inserted into a body cavity, typically the rectum or vagina. It dissolves or melts to release the medication for local or systemic absorption.

How does the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository work?

Once inserted into the body cavity, the suppository dissolves or melts, releasing the Morphine Sulfate and Metoclopramide. These medications are then absorbed into the body either locally or systemically, depending on the intended treatment.

What is this suppository used for?

The Morphine Sulfate/Metoclopramide suppository is typically used for pain management and to treat conditions like nausea and vomiting. However, the specific use may vary depending on the patient's condition and doctor's prescription.

How should I use this suppository?

This suppository should be used as directed by your healthcare provider. It is typically inserted into the rectum or vagina. Wash your hands before and after use, and try to hold the suppository in for as long as possible to allow the medication to be fully absorbed.

What are the potential side effects of this suppository?

Side effects can vary depending on the individual, but may include constipation, nausea, and dizziness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I use this suppository if I am pregnant or breastfeeding?

Always consult your healthcare provider before using any medication while pregnant or breastfeeding. They will be able to advise you on the potential risks and benefits.

Can I use this suppository with other medications?

Before using this suppository, inform your healthcare provider about any other medications you are currently taking. Some medications may interact with Morphine Sulfate and Metoclopramide, affecting their effectiveness or causing side effects.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use two doses at the same time or extra doses.

How should I store this suppository?

Store this suppository in a cool, dry place, away from direct heat and light. Keep it out of the reach of children and pets. Do not use it if the suppository appears damaged or if the packaging is torn.

What should I do in case of an overdose?

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include severe drowsiness, slow breathing, or loss of consciousness.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.