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Morphine Sulfate 45 mg Slow Release Capsules

Morphine Sulfate 45 mg Slow Release Capsules are compounded with Methocel E4M, a controlled-release polymer. This formulation is designed to gradually release the active ingredient over an extended period, providing sustained therapeutic effects. This reduces the need for frequent dosing and improves patient compliance. These capsules are used to manage various types of pain including chronic, cancer, postoperative, neuropathic, and arthritis pain.

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Morphine Sulfate
Slow Release Capsules
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Formula Information

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Morphine Sulfate 45 mg Slow Release Capsules are a potent, long-acting opioid analgesic designed to manage moderate to severe pain. This formulation is specifically engineered to provide a steady, consistent release of the active ingredient, Morphine Sulfate, over an extended period of time. This slow release mechanism allows for more effective pain relief with fewer side effects, making it an ideal choice for managing pain associated with cancer, post-operative recovery, and chronic pain conditions.

The slow release formulation of Morphine Sulfate 45 mg Capsules is achieved through the use of Methocel E4M, a type of controlled-release polymer. This polymer is designed to gradually release the encapsulated medication over time, offering sustained therapeutic effects, reduced dosing frequency, and improved patient compliance for medications requiring a controlled and prolonged release profile.

However, this formulation is not recommended for patients with acute pain, as the slow release mechanism may not provide immediate pain relief. Patients should also be aware of potential side effects, which may include drowsiness, dizziness, and confusion. It is advised not to drive or operate machinery while taking this medication. Furthermore, this medication has the potential to be habit-forming and should not be taken for longer than prescribed.

Prescribers should exercise caution when prescribing this formulation of Morphine Sulfate 45 mg Capsules, particularly in patients with a history of substance abuse or addiction. This medication is a long-acting opioid analgesic and can cause respiratory depression, so it should be used with caution in patients with respiratory conditions.

If you have any questions or concerns about Morphine Sulfate 45 mg Slow Release Capsules, please do not hesitate to contact us at Bayview Pharmacy. Our team of experienced compounding pharmacists is here to provide the information and support you need.

Drug Interactions

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Morphine Sulfate 45 mg Slow Release Capsules are a potent analgesic medication, specifically designed for the management of moderate to severe pain. This formulation utilizes Methocel E4M, a type of controlled-release polymer, which ensures a gradual release of the active ingredient over an extended period. This slow-release mechanism offers sustained therapeutic effects, reduces the need for frequent dosing, and enhances patient compliance, particularly for those requiring a controlled and prolonged release profile.

It is crucial to note that Morphine Sulfate 45 mg Slow Release Capsules should not be administered to patients with a known hypersensitivity to morphine or other opioids. Additionally, it is contraindicated in patients with significant respiratory depression. Regular monitoring for signs of respiratory depression, sedation, and hypotension is recommended during the course of treatment. Furthermore, vigilance for signs of opioid addiction, abuse, and misuse is necessary.

Special caution is advised when prescribing Morphine Sulfate 45 mg Slow Release Capsules to patients with renal or hepatic impairment, as well as in elderly patients, due to the potential for increased sensitivity or altered pharmacokinetics. Patients should be counseled to avoid alcohol and other CNS depressants while on this medication, as it may potentiate the sedative effects. Additionally, patients should be advised to refrain from activities requiring mental alertness, such as driving or operating machinery, until they are fully aware of how this medication affects them.

How Does it Work

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Morphine Sulfate 45 mg Slow Release Capsules are a potent, extended-release opioid medication designed to manage moderate to severe pain. These capsules are formulated with Methocel E4M, a type of controlled-release polymer, which ensures the gradual release of the encapsulated medication over an extended period. This slow-release mechanism provides a consistent level of pain relief, reducing the need for frequent dosing and enhancing patient compliance.

The capsules are administered orally, typically once a day, and should be consumed with food. It is crucial to adhere to the prescribed dosage and frequency set by your healthcare provider. Overdosing or underdosing, as well as taking the medication more frequently than advised, can lead to adverse effects or diminished efficacy.

Morphine Sulfate 45 mg Slow Release Capsules are versatile in their application, providing relief from chronic pain, cancer-related pain, and post-operative discomfort. They can also be used to manage pain associated with end-stage renal disease, sickle cell anemia, and other debilitating conditions.

While effective, Morphine Sulfate 45 mg Slow Release Capsules can cause side effects such as nausea, vomiting, constipation, drowsiness, and dizziness. More severe side effects can include respiratory depression, which can be life-threatening. It is essential to communicate with your healthcare provider about any side effects experienced while on this medication.

If you have any queries or concerns about Morphine Sulfate 45 mg Slow Release Capsules, do not hesitate to seek professional advice. Understanding how this medication works and how it can help manage your pain is key to effective treatment.

Other Uses

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Morphine Sulfate 45 mg Slow Release Capsules are a potent analgesic formulation designed to provide sustained relief from various types of pain, including musculoskeletal pain, fibromyalgia, and headaches. The slow-release mechanism, facilitated by Methocel E4M, a controlled-release polymer, ensures a gradual release of the active ingredient over an extended period, thereby reducing the dosing frequency and enhancing patient compliance.

These capsules are not only effective in managing pain but also beneficial in treating dyspnea or shortness of breath in patients with advanced cancer. They can also be used to alleviate the discomfort of opioid-induced constipation and to mitigate the severity of withdrawal symptoms in patients with opioid dependence.

However, caution should be exercised when prescribing Morphine Sulfate 45 mg Slow Release Capsules to patients with renal or hepatic impairment, as well as those with a history of substance abuse. Regular monitoring for signs of respiratory depression, sedation, and constipation is recommended to ensure patient safety and efficacy of the treatment.

It is important to note that while this formulation offers numerous therapeutic benefits, it should be used as directed by a healthcare professional. If you have any questions or concerns about the use of Morphine Sulfate 45 mg Slow Release Capsules for any of these indications, it is advised to consult with a healthcare provider.

Frequently Asked Questions

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What is Morphine Sulfate 45 mg Slow Release Capsules?

Morphine Sulfate 45 mg Slow Release Capsules is a medication formulated with Methocel E4M, a type of controlled-release polymer. This formulation is designed to release the encapsulated medication gradually over an extended period of time.

What is the purpose of the controlled-release polymer in this medication?

The controlled-release polymer, Methocel E4M, is designed to gradually release the medication over an extended period of time. This offers sustained therapeutic effects, reduces the frequency of dosing, and improves patient compliance for medications requiring a controlled and prolonged release profile.

What are the benefits of a slow-release formulation?

Slow-release formulations like Morphine Sulfate 45 mg Slow Release Capsules offer several benefits. They provide sustained therapeutic effects, reduce the need for frequent dosing, and improve patient compliance, especially for medications that require a controlled and prolonged release profile.

How does Morphine Sulfate 45 mg Slow Release Capsules work?

The Morphine Sulfate 45 mg Slow Release Capsules work by gradually releasing the active ingredient, morphine sulfate, over an extended period of time. This is achieved through the use of a controlled-release polymer, Methocel E4M.

How often should I take Morphine Sulfate 45 mg Slow Release Capsules?

The frequency of dosing for Morphine Sulfate 45 mg Slow Release Capsules will depend on your doctor's prescription. The slow-release formulation is designed to reduce the frequency of dosing while maintaining therapeutic effects.

What should I do if I miss a dose?

If you miss a dose of Morphine Sulfate 45 mg Slow Release Capsules, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Can I crush or break the Morphine Sulfate 45 mg Slow Release Capsules?

No, you should not crush or break Morphine Sulfate 45 mg Slow Release Capsules. Doing so can release all of the drug at once, increasing the risk of morphine overdose.

What are the potential side effects of Morphine Sulfate 45 mg Slow Release Capsules?

Common side effects of Morphine Sulfate 45 mg Slow Release Capsules may include constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. You should contact your doctor if these symptoms persist or worsen.

Can I drink alcohol while taking Morphine Sulfate 45 mg Slow Release Capsules?

No, you should not drink alcohol while taking Morphine Sulfate 45 mg Slow Release Capsules. Mixing morphine with alcohol can increase the risk of dangerous side effects or death.

Who should not take Morphine Sulfate 45 mg Slow Release Capsules?

People with certain conditions should not take Morphine Sulfate 45 mg Slow Release Capsules. These conditions include severe asthma or breathing problems, a blockage in your stomach or intestines, or a hypersensitivity to morphine. Always consult your doctor before starting any new medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.