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Formulas

Montelukast Sodium 4.16 mg/3 mL Oral Liquid

Our Montelukast Sodium 4.16 mg/3 mL Oral Liquid is a specially crafted medication designed for ease of administration and precise dosing. This oral liquid formulation is ideal for patients who experience difficulty swallowing solid dosage forms, including pediatric and geriatric populations. Montelukast is a leukotriene receptor antagonist that effectively treats and manages asthma, preventing wheezing and shortness of breath. Additionally, it is used to alleviate symptoms of allergic rhinitis, such as sneezing, stuffy nose, and itchy, watery eyes. This formulation ensures that patients receive the exact amount of medication needed for effective management of these disease states.

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Montelukast Sodium
Oral Liquid
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Formula Information

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Montelukast Sodium 4.16 mg/3 mL Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This oral liquid formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as children and the elderly. Montelukast, the active ingredient, is a leukotriene receptor antagonist that works by blocking substances in the body called leukotrienes. Leukotrienes are involved in the inflammatory process that triggers asthma and allergic rhinitis symptoms. By inhibiting these substances, montelukast helps to prevent wheezing, difficulty breathing, chest tightness, and coughing caused by asthma. It is also effective in preventing the stuffy, runny nose, and sneezing associated with seasonal or perennial allergic rhinitis.

The 4.16 mg/3 mL strength allows for flexible dosing, which can be adjusted according to the specific needs of the patient. This is particularly important in pediatric patients, where dosing often needs to be precise and tailored to the child's weight. The liquid form ensures that the medication can be measured and administered accurately, ensuring therapeutic effectiveness while minimizing the risk of side effects. It is important for prescribers to consider the patient's age, weight, and severity of symptoms when determining the appropriate dose. Additionally, patients or caregivers should be instructed on how to measure and administer the liquid correctly, and to adhere to the prescribed dosing schedule for optimal management of their condition.

For those interested in using Montelukast Sodium 4.16 mg/3 mL Oral Liquid, it is essential to understand that while it can help control the symptoms of asthma and allergic rhinitis, it is not intended for the relief of acute bronchospasm or as a substitute for inhaled or oral corticosteroids. Patients should continue taking other medications as directed by their healthcare provider and should consult their provider if their symptoms do not improve or if they worsen. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support and guidance to both patients and prescribers.

Drug Interactions

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Montelukast Sodium is a leukotriene receptor antagonist that is commonly used to manage symptoms of asthma and to relieve symptoms of seasonal allergies. When considering the use of Montelukast Sodium 4.16 mg/3 mL Oral Liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects.

Montelukast may interact with drugs that are metabolized by the cytochrome P450 system, particularly the CYP2C8 and CYP3A4 isoenzymes. Concurrent use with drugs that induce CYP2C8, such as rifampin, could potentially decrease the plasma concentration of montelukast, leading to reduced effectiveness. Conversely, inhibitors of CYP2C8, such as gemfibrozil, may increase the plasma levels of montelukast, potentially increasing the risk of side effects.

Additionally, caution should be exercised when montelukast is co-administered with other medications known to prolong the QT interval, as there is a theoretical risk of additive effects on the QT interval, although montelukast itself is not known to have any significant effects on cardiac conduction. Patients taking medications with a narrow therapeutic index, such as warfarin, should be monitored closely, as montelukast may alter the plasma concentrations of these drugs.

It is also important to consider the potential for drug interactions with over-the-counter (OTC) medications and herbal supplements. Patients should be advised to consult with their healthcare provider before starting any new medications, including OTC drugs and supplements, while taking montelukast.

Montelukast should be used with caution in patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs), as these medications may also affect leukotriene pathways. Although montelukast is not a substitute for corticosteroids or a rescue inhaler, it is important to maintain any prescribed asthma or allergy treatment regimen unless otherwise directed by a healthcare provider.

Patients with phenylketonuria should be aware that montelukast chewable tablets may contain phenylalanine, which can be harmful in high amounts for those with this condition. However, this is specific to the chewable tablet formulation and may not be relevant for the oral liquid form described here.

As with any medication, the potential for drug interactions with montelukast should be assessed on an individual basis, taking into account all concomitant medications, including prescription drugs, OTC medications, and herbal supplements. Healthcare providers should review the patient's medication regimen to identify any possible interactions and adjust therapy as needed to ensure safe and effective use of montelukast.

If you have any questions or require further information regarding drug interactions with Montelukast Sodium 4.16 mg/3 mL Oral Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to both patients and prescribers to ensure optimal treatment outcomes.

How Does it Work

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The Montelukast Sodium 4.16 mg/3 mL Oral Liquid is a specially designed medication that works by targeting the pathways in the body responsible for inflammation and allergic reactions. Montelukast is a leukotriene receptor antagonist, which means it blocks the action of leukotrienes in the body. Leukotrienes are chemicals produced by the body in response to allergens or other triggers and are responsible for symptoms such as swelling, inflammation, and constriction of airways in the lungs.

When a patient takes this oral liquid, the active ingredient, Montelukast Sodium, is absorbed into the bloodstream through the digestive tract. Once absorbed, it selectively binds to the cysteinyl leukotriene receptors in the lungs and bronchial tubes, preventing leukotrienes from causing their usual effects. This action helps to reduce bronchoconstriction (narrowing of the airways), mucus production, and inflammation, leading to relief from symptoms of asthma and allergic rhinitis (such as sneezing, stuffy nose, and itchy, watery eyes).

This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as young children or the elderly, as well as those with conditions that affect their ability to swallow solid dosage forms. The liquid form allows for precise dosing, which is critical for effective management of the conditions being treated. Additionally, the oral liquid can be more palatable and easier to administer, which is an important consideration for maintaining patient adherence to a medication regimen.

Montelukast Sodium Oral Liquid is used in the treatment of asthma to prevent asthma attacks and to decrease the number of acute asthma attacks. It is also used before exercise to prevent breathing problems during exercise (bronchospasm). In patients with allergic rhinitis, it alleviates symptoms such as a runny nose, sneezing, and itching. It is important to note that this medication is not intended for the relief of acute bronchospasm or asthma attacks and should not be used as a rescue medication.

For optimal results, the medication should be taken regularly as prescribed by a healthcare provider. It is also important to continue taking the medication as directed even if symptoms improve, as it is meant for long-term control and not just for immediate symptom relief. If you have any questions about how Montelukast Sodium Oral Liquid works or if it is the right medication for your condition, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to manage your health effectively.

Other Uses

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Montelukast Sodium, the active ingredient in this 4.16 mg/3 mL oral liquid formulation, is primarily prescribed for the management of asthma and the relief of symptoms of allergic rhinitis (e.g., sneezing, stuffy nose, runny nose, itching of the nose). However, beyond these common indications, the compound has found utility in an off-label capacity for several other conditions, although these are not as well-established in clinical guidelines.

Some patients with exercise-induced bronchoconstriction (EIB) may benefit from Montelukast Sodium as it can help prevent bronchospasm triggered by physical activity. Additionally, this liquid formulation might be used off-label in the management of urticaria, commonly known as hives, where leukotriene receptor antagonism by montelukast can mitigate the allergic responses that often contribute to the skin's reaction.

Moreover, due to its anti-inflammatory properties, Montelukast Sodium has been studied in the context of other inflammatory conditions, such as atopic dermatitis and even eosinophilic esophagitis. Although not standard treatment for these conditions, there is an expanding body of research that suggests potential benefits in selected cases, and therefore, montelukast may be prescribed as an adjunct therapy.

It is important to underline that the majority of montelukast's alternative uses are considered 'off-label' and they have not been approved by regulatory agencies like the FDA. Physicians prescribing Montelukast Sodium for off-label uses should rely on their clinical judgment and current scientific evidence. Pharmacists at Bayview Pharmacy are equipped to prepare this oral liquid formulation and are available to discuss both the established and emerging uses of Montelukast Sodium, providing guidance to healthcare providers on potential compounding options. If you have any questions regarding this medication or its suitability for alternate uses, please reach out to us for more information.

Frequently Asked Questions

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What is Montelukast Sodium 4.16 mg/3 mL Oral Liquid used for?

This liquid formulation of Montelukast is used to treat and prevent asthma, relieve symptoms of allergic rhinitis, and prevent exercise-induced bronchoconstriction. It is especially beneficial for patients who have difficulty swallowing pills or for those who require a precise dosage that can be easily adjusted.

How should Montelukast Sodium Oral Liquid be stored?

Montelukast Sodium Oral Liquid should be stored at room temperature, away from direct light, heat, and moisture. Keep the bottle tightly closed when not in use and out of reach of children and pets to ensure safety.

Can the dosage of Montelukast Sodium Oral Liquid be adjusted?

Yes, the dosage can be adjusted according to the prescribing physician's guidance. The liquid formulation allows for precise dosing, which is particularly useful for pediatric and geriatric patients who may need doses that are not standard in pill form.

What are the potential side effects of taking Montelukast Sodium Oral Liquid?

Common side effects may include headache, dizziness, abdominal pain, and cough. Serious side effects are rare but can include mood changes, increased bleeding tendency, and allergic reactions. Contact your healthcare provider if you experience any unusual symptoms.

Can Montelukast Sodium Oral Liquid be taken with other medications?

Montelukast may interact with certain medications, so it is important to inform your healthcare provider of all medications you are taking, including over-the-counter drugs and supplements, to prevent potential interactions.

Is Montelukast Sodium Oral Liquid suitable for children?

Yes, this liquid formulation is often prescribed for children, as it is easier for them to ingest compared to solid pills. The dosage should be determined by a pediatrician based on the child's weight and age.

How do you measure the correct dose of Montelukast Sodium Oral Liquid?

The correct dose should be measured using the dosing syringe, cup, or spoon that comes with the medication to ensure accuracy. Household spoons should not be used as they can lead to incorrect dosing.

What if a dose of Montelukast Sodium Oral Liquid is missed?

If a dose is missed, take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can Montelukast Sodium Oral Liquid be mixed with food or liquids?

It is best to take the medication as directed by your healthcare provider. While it can be administered directly, some physicians may allow it to be mixed with a small amount of food or liquid if it helps with ingestion. Check with your healthcare provider for specific instructions.

Are there any dietary restrictions while taking Montelukast Sodium Oral Liquid?

There are generally no specific dietary restrictions while taking Montelukast Sodium Oral Liquid, but it is important to discuss your diet and potential food-drug interactions with your doctor. Additionally, some patients may be advised to avoid certain foods that trigger their asthma symptoms.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.