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Formulas

Metoclopramide 20 mg/Dexamethasone 10 mg/Diphenhydramine HCl 50 mg Suppository

This is a compounded suppository formulation containing Metoclopramide 20 mg, Dexamethasone 10 mg, and Diphenhydramine HCl 50 mg. It is designed to be inserted into a body cavity, where it dissolves or melts to release the medication. This formulation is typically used for the treatment of conditions such as nausea, vomiting, gastroparesis, gastroesophageal reflux disease, and motion sickness.

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Formula Information

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This compounded suppository formulation is composed of Metoclopramide 20 mg, Dexamethasone 10 mg, and Diphenhydramine HCl 50 mg. It is designed to be inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication. This allows for local or systemic absorption of the active ingredients, providing effective treatment for a variety of conditions.

The formulation is primarily used to manage symptoms such as nausea, vomiting, and motion sickness. It is also effective in reducing inflammation and itching associated with certain skin conditions. Furthermore, it can be utilized to mitigate the severity of allergic reactions, thanks to the combined action of its active ingredients.

Metoclopramide, a dopamine antagonist, works by reducing feelings of nausea and vomiting. Dexamethasone, a corticosteroid, aids in reducing inflammation and itching. Diphenhydramine HCl, an antihistamine, is instrumental in reducing the severity of allergic reactions. The synergistic effect of these ingredients makes this formulation an effective treatment option for a variety of conditions.

When used as directed, this suppository formulation is safe and generally well-tolerated. However, as with any medication, it is important to follow the prescribed dosage and administration instructions to ensure optimal effectiveness and minimize potential side effects. If you have any questions or concerns about this formulation, please do not hesitate to contact us at Bayview Pharmacy. We are committed to providing comprehensive information and support to ensure the best possible patient outcomes.

Drug Interactions

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This compounded formulation of Metoclopramide 20 mg, Dexamethasone 10 mg, and Diphenhydramine HCl 50 mg is a suppository that is inserted into a body cavity, typically the rectum or vagina. It dissolves or melts to release medication for local or systemic absorption. It is important to note that these medications may interact with other drugs, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Therefore, patients should inform their healthcare provider of all medications they are currently taking, including any herbal supplements, before using this suppository.

Metoclopramide may interact with anticholinergic medications, such as atropine, scopolamine, and benztropine, as well as other dopamine antagonists, such as phenothiazines and butyrophenones. It may also interact with anticoagulants, such as warfarin, and other medications used to treat nausea and vomiting, such as ondansetron.

Dexamethasone may interact with anticholinergic medications, such as atropine, scopolamine, and benztropine, as well as other corticosteroids, such as prednisone and hydrocortisone. It may also interact with anticoagulants, such as warfarin, and other medications used to treat inflammation, such as ibuprofen and naproxen.

Diphenhydramine HCl may interact with anticholinergic medications, such as atropine, scopolamine, and benztropine, as well as other antihistamines, such as cetirizine and loratadine. It may also interact with anticoagulants, such as warfarin, and other medications used to treat allergies, such as diphenhydramine and chlorpheniramine.

This suppository is used to treat nausea, vomiting, and inflammation. It should not be used in patients with a known hypersensitivity to any of the ingredients. Patients should be monitored for signs and symptoms of adverse reactions, such as dizziness, drowsiness, and difficulty breathing. If you have any questions about the interactions of this suppository, please consult with your healthcare provider.

How Does it Work

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This compounded formulation of Metoclopramide 20 mg/Dexamethasone 10 mg/Diphenhydramine HCl 50 mg Suppository is a multi-purpose medication designed to address a range of symptoms. Metoclopramide, a dopamine antagonist, is effective in reducing nausea and vomiting. Dexamethasone, a corticosteroid, is instrumental in reducing inflammation and swelling. Diphenhydramine HCl, an antihistamine, is used to alleviate itching and other allergic reactions. The combined effect of these three medications helps to alleviate the symptoms associated with various disease states.

When using this medication, it is crucial to adhere to the instructions provided by your healthcare provider. The suppository should be inserted into the rectum as directed. It is essential to use the correct dosage and not exceed the recommended amount. Consistency is key, so ensure that the suppository is used at the same time each day to guarantee optimal absorption of the medication.

If you have any queries about this formulation or its mechanism of action, do not hesitate to seek clarification. It is important to understand your medication to achieve the best possible results from your treatment. Remember, your healthcare provider is your best resource for any questions or concerns you may have regarding your medication.

Other Uses

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This compounded formulation of Metoclopramide 20 mg/Dexamethasone 10 mg/Diphenhydramine HCl 50 mg Suppository is a versatile medication with a range of potential uses. Metoclopramide, a dopamine antagonist, is primarily used to alleviate nausea and vomiting. It can also be effective in reducing the severity of migraine symptoms and the intensity of vertigo symptoms. Dexamethasone, a corticosteroid, is known for its ability to reduce inflammation and itching. Lastly, Diphenhydramine HCl, an antihistamine, is used to mitigate allergic reactions. This formulation, therefore, may be used to treat a variety of conditions including allergic reactions, inflammation, itching, migraine headaches, and vertigo. Please consult with a healthcare professional for advice on the use of this formulation for any of these conditions.

Frequently Asked Questions

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What is the Metoclopramide 20 mg/Dexamethasone 10 mg/Diphenhydramine HCl 50 mg Suppository?

This is a compounded medication that combines Metoclopramide, Dexamethasone, and Diphenhydramine HCl in a solid dosage form. It is designed to be inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

What is the purpose of this medication?

This medication is typically used to treat a variety of conditions, including nausea, vomiting, allergies, and inflammation. The specific combination of drugs can help to alleviate these symptoms and provide relief.

How should I use this suppository?

This suppository should be inserted into the rectum or vagina as directed by your healthcare provider. It will dissolve or melt to release the medication.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

What are the potential side effects of this medication?

Side effects may include drowsiness, dizziness, and dry mouth. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Can I take this medication if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. The effects on the fetus or infant are not fully known.

Can I use this medication with other drugs?

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of other drugs that may interact with Metoclopramide, Dexamethasone, or Diphenhydramine HCl.

What should I do in case of an overdose?

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call emergency services immediately. Otherwise, call a poison control center right away.

How should I store this medication?

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

What should I do if I have an allergic reaction to this medication?

If you have an allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing, seek medical attention immediately.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.