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Formulas

Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension

The Melatonin 1 mg/mL and Pyridoxine HCl 0.1 mg/mL Oral Suspension is a liquid dosage form where melatonin and pyridoxine hydrochloride are uniformly dispersed in a liquid medium, ensuring a homogeneous mixture for precise administration.

This formulation is primarily used to treat sleep disorders, such as insomnia, and may also aid in managing symptoms associated with jet lag and circadian rhythm sleep disorders. Additionally, the inclusion of pyridoxine HCl supports the treatment of vitamin B6 deficiency, which can contribute to neurological and sleep-related issues.

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Melatonin
Pyridoxine Hydrochloride
Suspension
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Formula Information

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Drug Interactions

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Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension is a compounded liquid formulation designed to provide a homogeneous mixture for ease of administration. This formulation is often used to address conditions related to sleep disturbances and vitamin B6 deficiency. Melatonin is a hormone that regulates sleep-wake cycles, and pyridoxine (vitamin B6) plays a crucial role in neurotransmitter synthesis, which can influence mood and sleep patterns.

When considering the use of this formulation, it is important to be aware of potential drug interactions that may affect its efficacy or safety. Melatonin can interact with a variety of medications. For instance, it may enhance the sedative effects of central nervous system depressants such as benzodiazepines, barbiturates, and alcohol, potentially leading to increased drowsiness or impaired motor skills. Patients taking anticoagulants or antiplatelet drugs should use melatonin with caution, as it may increase the risk of bleeding. Additionally, melatonin may interact with immunosuppressants, potentially affecting immune function, and with medications that affect the cytochrome P450 enzyme system, such as fluvoxamine, which can alter melatonin metabolism.

Pyridoxine, on the other hand, may interact with certain medications as well. It can reduce the efficacy of levodopa in patients with Parkinson's disease unless a dopa decarboxylase inhibitor is also used. High doses of pyridoxine may decrease the effectiveness of phenobarbital and phenytoin, which are used to control seizures. Furthermore, pyridoxine can interfere with the metabolism of certain medications, such as isoniazid, hydralazine, and penicillamine, potentially necessitating dosage adjustments.

Patients and prescribers should also consider the potential for additive effects when using this formulation in conjunction with other supplements or herbal products that have sedative properties, such as valerian root or kava. It is advisable to monitor for any changes in sleep patterns, mood, or other symptoms that may indicate an interaction.

As with any medication, it is crucial to discuss all current medications, supplements, and underlying health conditions with a healthcare provider before starting this formulation. This will help ensure that any potential interactions are identified and managed appropriately. If you have any questions or concerns about using Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension, please reach out to us for further guidance and support.

How Does it Work

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The Melatonin 1 mg/mL and Pyridoxine HCl 0.1 mg/mL Oral Suspension is a compounded liquid formulation designed to deliver precise doses of melatonin and pyridoxine hydrochloride in a convenient and easily administered form. This suspension is particularly beneficial for patients who may have difficulty swallowing tablets or capsules, such as pediatric or geriatric populations, or those with specific medical conditions that impair swallowing.

Melatonin is a naturally occurring hormone produced by the pineal gland in the brain, primarily responsible for regulating sleep-wake cycles. It is often used in the management of sleep disorders, such as insomnia or delayed sleep phase disorder, by helping to adjust the body's internal clock. In this formulation, melatonin is provided at a concentration of 1 mg/mL, allowing for flexible dosing tailored to the individual needs of the patient. This can be particularly useful in pediatric patients or those with specific sleep disorders where precise dosing is crucial for efficacy and safety.

Pyridoxine hydrochloride, also known as vitamin B6, is an essential nutrient that plays a vital role in numerous physiological functions, including neurotransmitter synthesis, amino acid metabolism, and hemoglobin production. In the context of this formulation, pyridoxine is included at a concentration of 0.1 mg/mL. It is often used to support neurological function and may be beneficial in conditions where vitamin B6 deficiency is a concern or where enhanced neurological support is desired. Additionally, pyridoxine has been studied for its potential role in reducing symptoms of certain neurological disorders and improving mood regulation.

The liquid suspension form ensures that both melatonin and pyridoxine are evenly distributed throughout the medium, providing a homogeneous mixture that ensures consistent dosing with each administration. This is particularly important for maintaining therapeutic efficacy and minimizing the risk of under- or overdosing. The suspension can be easily measured using an oral syringe or dosing cup, allowing for accurate and individualized dosing based on the patient's specific needs and response to treatment.

For prescribers, this formulation offers a customizable approach to managing sleep disorders and supporting neurological health, with the flexibility to adjust doses as needed. For patients, it provides a user-friendly option that can be easily incorporated into their daily routine, enhancing adherence to treatment regimens. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or specific compounding needs you may have.

Other Uses

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The Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension is a versatile formulation that may have applications beyond its primary indications. Melatonin, a hormone naturally produced by the pineal gland, is widely recognized for its role in regulating sleep-wake cycles. However, its potential benefits extend to other areas, such as supporting immune function, managing symptoms of jet lag, and providing adjunctive therapy for certain neurological conditions. Melatonin's antioxidant properties may also contribute to cellular protection, potentially offering benefits in conditions characterized by oxidative stress.

Pyridoxine HCl, commonly known as Vitamin B6, plays a crucial role in numerous physiological functions, including amino acid metabolism, neurotransmitter synthesis, and hemoglobin production. Beyond its primary uses, pyridoxine may aid in alleviating symptoms of premenstrual syndrome (PMS), reducing nausea during pregnancy, and supporting cognitive health. Its involvement in neurotransmitter synthesis suggests potential benefits in mood regulation and the management of certain mood disorders.

When combined in an oral suspension, melatonin and pyridoxine HCl may offer synergistic effects, potentially enhancing their individual benefits. This formulation could be considered for patients who require a liquid dosage form due to swallowing difficulties or those who need precise dosing adjustments. The homogeneous mixture ensures consistent delivery of active ingredients, which is particularly beneficial for pediatric or geriatric populations.

As with any compounded medication, it is essential for prescribers to evaluate the specific needs of their patients and consider potential interactions with other medications. Patients should be informed about the possible benefits and limitations of this formulation, and any off-label use should be guided by clinical judgment and evidence-based practice. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

Frequently Asked Questions

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What is Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension?

Melatonin 1 mg/mL/Pyridoxine HCl 0.1 mg/mL Oral Suspension is a liquid dosage form where melatonin and pyridoxine hydrochloride are uniformly dispersed in a liquid medium, creating a homogeneous mixture for easy administration.

How should I store this oral suspension?

This oral suspension should be stored in a cool, dry place away from direct sunlight. It is important to keep it out of reach of children and to follow any specific storage instructions provided by your pharmacist or healthcare provider.

What is the purpose of melatonin in this formulation?

Melatonin is a hormone that helps regulate sleep-wake cycles. In this formulation, it is used to aid in the management of sleep disorders or to help improve sleep quality.

What role does pyridoxine HCl play in this suspension?

Pyridoxine HCl, also known as vitamin B6, is included in this formulation to support various bodily functions, including neurotransmitter synthesis and immune function, which can contribute to overall health and well-being.

How do I take this oral suspension?

Shake the bottle well before each use to ensure the ingredients are evenly distributed. Use a measuring device, such as a syringe or dosing cup, to ensure accurate dosing as prescribed by your healthcare provider.

Can I take this suspension with other medications?

Before taking this suspension with other medications, consult your healthcare provider or pharmacist to avoid potential interactions. They can provide guidance based on your specific health needs and medication regimen.

Are there any side effects associated with this oral suspension?

Some individuals may experience side effects such as drowsiness, headache, or gastrointestinal discomfort. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Is this formulation suitable for children?

The suitability of this formulation for children depends on the specific health needs and age of the child. It is important to consult a pediatrician or healthcare provider before administering this suspension to a child.

How long does it take for melatonin to work?

Melatonin typically begins to work within 30 minutes to an hour after ingestion. However, the onset of action can vary depending on individual factors such as metabolism and the presence of other substances in the body.

Can I adjust the dosage of this suspension on my own?

Do not adjust the dosage of this suspension without consulting your healthcare provider. They will determine the appropriate dosage based on your specific health needs and response to the medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.