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Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules

Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules are a solid dosage form consisting of two gelatin or vegetarian shells that encapsulate a combination of active ingredients. Each capsule delivers a precise dose of 375 mg of Magnesium Glycinate and 17 mg of Pyridoxine Hydrochloride (Vitamin B6). This formulation is designed for easy oral administration and is intended to support patients with deficiencies in magnesium and vitamin B6. Magnesium Glycinate is known for its high bioavailability and is used to treat conditions such as muscle cramps, restless leg syndrome, and to support bone health. Pyridoxine HCl is essential for various bodily functions, including neurotransmitter synthesis and energy metabolism, and is used to prevent or treat pyridoxine deficiency and its associated symptoms such as anemia and peripheral neuropathy. Together, these nutrients may also help in managing stress and anxiety, promoting cardiovascular health, and supporting overall well-being.

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Formula Information

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Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules are a solid dosage form that combines the therapeutic benefits of magnesium glycinate and pyridoxine hydrochloride (vitamin B6) in a convenient capsule. Each capsule is designed to deliver a precise dose of 375 mg of magnesium in the form of magnesium glycinate, a highly bioavailable form of magnesium, and 17 mg of pyridoxine HCl, ensuring optimal absorption and efficacy. The capsules are encased in either gelatin or vegetarian shells, catering to different dietary preferences and requirements.

Magnesium is an essential mineral that plays a pivotal role in numerous physiological processes, including muscle and nerve function, blood glucose control, and the production of energy. It is often used to treat or prevent magnesium deficiency, which can manifest as fatigue, muscle cramps, and irritability. Magnesium glycinate, specifically, is recognized for its enhanced absorption and minimal gastrointestinal side effects, making it a preferred choice for individuals with digestive sensitivities.

Pyridoxine HCl, or vitamin B6, is crucial for normal brain development and for keeping the nervous system and immune system healthy. It is involved in the metabolism of amino acids and neurotransmitters, the synthesis of nucleic acids, and the formation of hemoglobin. Pyridoxine supplementation is often indicated for the treatment of pyridoxine deficiency, sideroblastic anemia, and certain metabolic disorders. It also plays a supportive role in managing conditions such as premenstrual syndrome (PMS) and nausea during pregnancy.

The combination of magnesium glycinate and pyridoxine HCl in these oral capsules can be particularly beneficial for individuals with conditions that may involve both magnesium and vitamin B6 deficiencies or increased requirements. This formulation may also support overall well-being, contribute to stress reduction, and promote better sleep. It is important to note that while these capsules can help manage certain health conditions, they should not replace other medications or treatments prescribed by a healthcare provider.

For patients and prescribers considering this formulation, it is essential to understand the potential interactions with other medications and the appropriate dosing regimen. As with any supplement, it is recommended to consult with a healthcare professional before starting any new treatment. If you have any questions or require further information about the Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing expert guidance and support to ensure the safe and effective use of our formulations.

Drug Interactions

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Magnesium Glycinate and Pyridoxine HCl (Vitamin B6) are often used in combination due to their synergistic effects on various physiological processes. Magnesium is an essential mineral that plays a role in over 300 enzymatic reactions in the body, including those involved in protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. Pyridoxine is a water-soluble vitamin that is important for the metabolism of proteins, fats, and carbohydrates, the creation of red blood cells, and the proper functioning of nerves.

When considering drug interactions, it is important to note that magnesium can bind with certain medications, potentially reducing their absorption and effectiveness. These include bisphosphonates (used to treat osteoporosis), antibiotics like tetracycline and quinolone, and medications for osteoporosis or low blood phosphate levels (such as tiludronate or etidronate). To minimize this interaction, it is advisable to take magnesium supplements at least 2 hours before or 4-6 hours after these medications.

Pyridoxine can interact with certain drugs as well. For example, it can reduce the effectiveness of Levodopa, a medication used to treat Parkinson's disease, unless it is taken in combination with another medication that prevents pyridoxine from affecting Levodopa, such as carbidopa. Additionally, high doses of pyridoxine can decrease the efficacy of phenobarbital and phenytoin, two medications used to control seizures.

It is also worth noting that magnesium can affect the absorption of other minerals, such as calcium, potassium, and zinc. Therefore, patients taking supplements or medications containing these minerals should be aware of the potential for altered absorption when taken concurrently with magnesium supplements. Conversely, high doses of calcium and zinc may also affect magnesium absorption.

Patients with kidney disease need to exercise caution when taking magnesium supplements, as their kidneys may not be able to remove excess magnesium effectively, leading to toxicity. Similarly, excessive intake of pyridoxine can lead to nerve damage (neuropathy), and therefore, it is important to adhere to recommended dosages unless supervised by a healthcare provider.

Lastly, magnesium can have a laxative effect, and when taken in high doses, it may cause diarrhea, which can interfere with the absorption of oral medications. Pyridoxine, when taken in large amounts, can cause symptoms such as sensitivity to sunlight, nausea, and heartburn.

Given the potential for interactions, it is crucial for patients and prescribers to be aware of all medications and supplements being taken concurrently with Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules. If you have any questions or concerns about this formulation or its interactions with other drugs, please reach out to us at Bayview Pharmacy for personalized advice and guidance.

How Does it Work

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Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules are a solid dosage form that combines two active ingredients, magnesium in the form of magnesium glycinate and pyridoxine hydrochloride, which is vitamin B6. These capsules are designed to deliver a precise dose of these nutrients in a form that is easy to swallow and digest. The gelatin or vegetarian shells that make up the capsule are inert and dissolve upon ingestion, releasing the active compounds for absorption.

Magnesium glycinate is a chelated form of magnesium, which means the magnesium ion is bound to the amino acid glycine. This chelation process enhances the absorption of magnesium in the body, making it more bioavailable than other forms of magnesium. Magnesium is an essential mineral that plays a crucial role in numerous bodily functions, including muscle and nerve function, blood glucose control, and the production of energy. It is also important for the synthesis of DNA, RNA, and the antioxidant glutathione. Magnesium glycinate is often used to correct magnesium deficiency, which can manifest as fatigue, muscle cramps, and irritability. It is also used to support cardiovascular health and bone density.

Pyridoxine HCl, or vitamin B6, is a water-soluble vitamin that is vital for many processes in the body, including the metabolism of proteins, fats, and carbohydrates, the creation of red blood cells, and the proper functioning of nerves. It is also essential for the synthesis of neurotransmitters such as serotonin, dopamine, and GABA, which influence mood, sleep, and cognitive function. Pyridoxine can help manage conditions related to the nervous system and is also used to prevent or treat vitamin B6 deficiency.

Together, magnesium glycinate and pyridoxine HCl in these oral capsules can help support overall health, particularly in areas such as stress management, mood regulation, and muscle function. This combination may be beneficial for individuals with conditions such as magnesium deficiency, premenstrual syndrome (PMS), anxiety, and muscle cramps. It is also used to support cardiovascular health and may aid in the prevention of migraines.

It is important for patients and prescribers to understand that while this formulation can help manage certain health conditions, it is not intended to replace other medications or treatments prescribed by a healthcare provider. Patients should always consult with their healthcare provider before starting any new supplement, especially if they have underlying health conditions or are taking other medications. For more detailed information or if you have any questions about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support for your health and wellness needs.

Other Uses

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The formulation of magnesium glycinate 375 mg and pyridoxine HCl (vitamin B6) 17 mg in oral capsules is primarily intended for the dietary management of magnesium deficiency and vitamin B6 deficiency states, which can manifest in various health issues such as muscle weakness, nervousness, irritability, and insomnia. This combination is often prescribed with the indication of improving neuromuscular function and reducing the symptoms of premenstrual syndrome (PMS). Furthermore, it may support cardiovascular health by assisting in the regulation of heart rhythms and potentially reducing the risk of developing complications associated with magnesium deficiency, such as hypertension and ischemic heart disease.

Beyond these common uses, this unique formulation may have several other benefits. Magnesium plays a key role in bone health, and together with pyridoxine, may aid in the prevention of osteoporosis when incorporated as part of a comprehensive treatment plan with other medications and lifestyle modifications. In the realm of mental health, this combination has been of interest for its potential role in alleviating anxiety and supporting cognitive function due to the calming effects of magnesium and the role of pyridoxine in neurotransmitter synthesis.

Emerging research suggests that adequate levels of magnesium and vitamin B6 might contribute to better blood sugar control in patients with diabetes, as magnesium is involved in glucose metabolism, and B6 helps in the synthesis of insulin. Additionally, this formulation may offer benefits in reducing the frequency of migraine headaches, due to the vasodilatory and serotonin modulation action of magnesium, coupled with the role of vitamin B6 in neural function. However, efficacy in these roles should be evaluated on an individual basis.

It is important to note that the use of this formulation for any condition beyond the labeled indications should be done under the supervision of a healthcare provider as it may interact with other medications or may not be appropriate for all patient populations. Furthermore, while the oral capsule form offers the convenience of precise dosing and easy administration, it is essential to ensure that patients have no contraindications to the ingredients, and proper counseling is provided regarding potential side effects.

Patients and prescribers interested in this formulation for its various potential applications are encouraged to reach out to us at Bayview Pharmacy for additional information and individualized guidance. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide comprehensive support to optimize patient outcomes with this formulation.

Frequently Asked Questions

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What is the purpose of Magnesium Glycinate 375 mg/Pyridoxine HCl 17 mg Oral Capsules?

This compounded medication is designed to combine the benefits of magnesium glycerinate, which is a form of magnesium that is often better tolerated and absorbed by the body, with pyridoxine HCl, also known as vitamin B6. Together, they may be used to support various functions in the body, including muscle and nerve function, energy metabolism, and the production of neurotransmitters.

How should I take this compounded medication?

Take Magnesium Glycinate/Pyridoxine HCl Oral Capsules exactly as prescribed by your healthcare provider. The capsules should be swallowed whole with a glass of water, with or without food. Do not split, chew, or crush the capsules.

Can this medication cause side effects?

As with all medications, this compounded formulation may cause side effects in some individuals. Common side effects can include gastrointestinal discomfort, diarrhea, or nausea. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Who should not take Magnesium Glycinate/Pyridoxine HCl Capsules?

Individuals with kidney problems or certain metabolic disorders should consult with their healthcare provider before taking this medication. It is also not recommended for those who are allergic to any of the ingredients in the formulation.

Are these capsules suitable for vegetarians?

The medication can be encapsulated in either gelatin or vegetarian shells. If you require vegetarian capsules, please inform your healthcare provider or pharmacist to ensure your prescription is filled accordingly.

Will this medication interact with other drugs or supplements?

There may be potential interactions with other medications or supplements, especially those that also affect magnesium levels in the body. It's important to inform your healthcare provider about all medications and supplements you are taking to avoid possible drug interactions.

How should I store this medication?

Store the capsules at room temperature, away from direct light and moisture. Keep the medication out of reach of children and pets. Do not store in the bathroom or near a sink.

Can I take this medication if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should only take this medication if it has been prescribed by your healthcare provider. They will assess the benefits and risks related to your specific situation.

How long does it take for Magnesium Glycinate/Pyridoxine HCl Capsules to work?

The onset of action for this medication varies depending on the individual and their particular health conditions. Some may notice benefits within a few days, while for others it may take longer. Consistent use as directed by your healthcare provider is important for best results.

What should I do if I miss a dose?

If you miss a dose of your medication, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.