Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Liothyronine 7.5 mcg/mL Transdermal Gel

The Liothyronine 7.5 mcg/mL Transdermal Gel is a semisolid formulation designed for ease of use and precise dosing through a pump mechanism. This gel-like medication is applied topically to the skin, where it is absorbed systematically to treat conditions related to thyroid hormone deficiency. The transdermal delivery system is particularly beneficial for patients who require a steady release of the hormone or those who may have difficulties with oral administration.

Liothyronine is a synthetic form of the thyroid hormone triiodothyronine (T3) and is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also utilized in the management of myxedema coma, a severe form of hypothyroidism, and sometimes prescribed for patients who are unresponsive to levothyroxine (T4) alone. Additionally, this transdermal formulation may be indicated for patients with specific gastrointestinal issues that affect the absorption of oral thyroid medications or for those who have allergies to fillers or binders commonly found in oral tablets.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Topical Gel
65afed05c38e324419931a07
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

Liothyronine 7.5 mcg/mL Transdermal Gel is a specialized medication formulated for the management of certain thyroid-related conditions. Liothyronine, the active ingredient, is a synthetic form of triiodothyronine (T3), which is a hormone naturally produced by the thyroid gland. This hormone plays a crucial role in regulating metabolism, energy production, and many other vital bodily functions. The transdermal delivery system of this medication is designed to allow for the direct application of liothyronine to the skin, where it is absorbed into the bloodstream. This method of administration can be particularly beneficial for patients who have difficulties with oral ingestion or require a steady release of medication over time.

The semisolid gel formulation is dispensed through a pump mechanism, which ensures that each dose is measured accurately, reducing the risk of dosing errors. The consistency of the gel allows for easy application and can be particularly useful for patients who prefer a non-invasive and convenient alternative to oral or injectable forms of medication. The transdermal route also bypasses the gastrointestinal tract, which can be advantageous in patients with malabsorption issues or those on medications that interfere with the absorption of oral thyroid preparations.

This transdermal gel is indicated for the treatment of hypothyroidism, a condition where the thyroid gland does not produce sufficient amounts of thyroid hormones. It may also be used in the management of myxedema coma, a severe form of hypothyroidism, and in the suppression of thyroid-stimulating hormone (TSH) in the treatment of euthyroid goiters and in the management of thyroid cancer. By providing a consistent and controlled release of liothyronine, this formulation can help to normalize thyroid hormone levels, thereby improving symptoms such as fatigue, weight gain, and cold intolerance associated with hypothyroidism.

It is important for patients and prescribers to be aware that the use of liothyronine requires careful monitoring of thyroid function tests to ensure therapeutic levels are achieved without causing hyperthyroidism. The transdermal application may also lead to skin reactions, and the site of application should be rotated to prevent skin irritation. As with any medication, adherence to prescribed dosing and regular follow-up with healthcare providers are essential for optimal treatment outcomes.

If you have any questions or require further information about the Liothyronine 7.5 mcg/mL Transdermal Gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing support and guidance to ensure the safe and effective use of this medication.

Drug Interactions

A small arrow pointing down

Liothyronine is a synthetic form of the thyroid hormone triiodothyronine (T3) and is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used in the management of myxedema coma and sometimes in the treatment of thyroid cancer. The transdermal gel formulation is designed to deliver a consistent dose of liothyronine through the skin, which can be beneficial for patients who have difficulties with oral administration or for whom gastrointestinal absorption may be impaired.

When considering the use of liothyronine 7.5 mcg/mL transdermal gel, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects. Liothyronine can interact with a variety of medications, including antidiabetic drugs, anticoagulants, antidepressants, and other medications that affect thyroid hormone levels or function.

For instance, liothyronine may enhance the effects of anticoagulants such as warfarin, which could increase the risk of bleeding. Patients on anticoagulant therapy should have their clotting status closely monitored, and dosage adjustments may be necessary. Additionally, liothyronine can affect blood sugar levels, which may require adjustments in the dosing of insulin or oral hypoglycemic agents for diabetic patients.

Some antidepressants, particularly tricyclics, may have their effects increased by liothyronine, and careful monitoring is advised when these drugs are used concurrently. Conversely, liothyronine's effectiveness may be reduced by medications that decrease thyroid hormone levels or interfere with its action, such as glucocorticoids, beta-blockers, and some anticonvulsants. It is also important to note that certain substances, including soybean flour, cottonseed meal, walnuts, dietary fiber, and calcium or iron supplements, can decrease the absorption of thyroid hormones and should not be taken within several hours of applying the transdermal gel.

Patients should be advised to inform their healthcare provider of all medications, supplements, and over-the-counter drugs they are taking to ensure proper management of potential interactions. Regular monitoring of thyroid function tests is recommended to adjust the dose of liothyronine as necessary. If you have any questions or concerns regarding the use of liothyronine 7.5 mcg/mL transdermal gel or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

A small arrow pointing down

Liothyronine is a synthetic form of triiodothyronine (T3), which is a thyroid hormone naturally produced by the thyroid gland. The primary function of T3 is to regulate the body's metabolism, which includes the rate at which the body uses energy, produces heat, and consumes oxygen. When the thyroid gland does not produce sufficient amounts of thyroid hormones (a condition known as hypothyroidism), liothyronine can be prescribed to supplement the deficiency and help restore normal metabolic functions.

The 7.5 mcg/mL transdermal gel formulation of liothyronine is designed to deliver the hormone directly through the skin, into the systemic circulation. This route of administration can be particularly beneficial for patients who have difficulties with oral administration, such as gastrointestinal malabsorption issues, or for those who prefer a more steady release of medication throughout the day, which can sometimes be achieved with transdermal systems.

The gel is compounded in a semisolid base that allows for the medication to be evenly distributed throughout the formulation, ensuring consistent dosing with each application. The base is designed to facilitate the penetration of liothyronine through the skin barrier, where it can then enter the bloodstream. The use of a pump mechanism for dispensing the gel provides a convenient and hygienic method for patients to apply the medication, while also allowing for precise dosing. Each pump delivers a measured dose of the gel, which can be applied to an area of skin as directed by a healthcare provider.

In terms of treating disease states, this liothyronine transdermal gel is primarily used to treat hypothyroidism. By providing a steady absorption of T3 through the skin, it helps to normalize the metabolic processes that are slowed down when the thyroid is underactive. This can lead to an improvement in symptoms such as fatigue, weight gain, cold intolerance, and depression. Additionally, because the medication bypasses the gastrointestinal tract, it may be advantageous for patients who have conditions that interfere with the absorption of oral medications.

It is important for both patients and prescribers to understand that the effectiveness of the transdermal gel can be influenced by various factors, including the site of application, skin integrity, and other individual patient variables. Regular monitoring of thyroid function tests is necessary to ensure that the dose of liothyronine is appropriate and to adjust the dose as needed.

If you have any questions about this formulation or its use in treating hypothyroidism, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your condition.

Other Uses

A small arrow pointing down

Liothyronine is a synthetic form of the thyroid hormone triiodothyronine (T3), which is primarily used to treat hypothyroidism and various thyroid disorders where there is a deficiency of thyroid hormone. Beyond its conventional usage, there may be other off-label uses for liothyronine transdermal gel that healthcare providers might consider based on their clinical judgment and the specific needs of their patients. For instance, it can be explored in circumstances where patients have difficulties with gastrointestinal absorption or where traditional oral administration of thyroid hormones is not effective or feasible. Additionally, this transdermal formulation can be beneficial in managing conditions that require a steady release of the hormone over extended periods, potentially improving the consistency of thyroid levels in the bloodstream.

Moreover, in instances of skin disorders that are indirectly related to thyroid function, such as myxedema, where the skin becomes thick and dry, this transdermal gel might offer direct application benefits. Additionally, some emerging research suggests various components of thyroid hormones can influence wound healing processes, which could open up an investigative avenue for the use of transdermal liothyronine in this context. However, such applications would be experimental and should be pursued under the guidance of a healthcare professional, within the context of an appropriate study or clinical trial if applicable.

It should be emphasized that liothyronine transdermal gel is not indicated for weight loss and should not be utilized for this purpose. Its use should be strictly under the direction of a healthcare provider experienced in the treatment of thyroid disorders. For patients and prescribers considering this compound formulation for alternative uses, it's essential to engage in a thorough discussion about the risks, benefits, and supporting evidence behind such applications. We encourage an open dialogue to ensure safety and efficacy and to align with best practice guidelines. If there are any questions or additional information needed regarding the potential uses and administration of liothyronine 7.5 mcg/mL transdermal gel, please do not hesitate to reach out to us at Bayview Pharmacy for further assistance.

Frequently Asked Questions

A small arrow pointing down

What is Liothyronine 7.5 mcg/mL Transdermal Gel?

Liothyronine 7.5 mcg/mL Transdermal Gel is a medication formulated for the treatment of certain conditions related to thyroid hormone deficiency, such as hypothyroidism. The active ingredient, Liothyronine, is a synthetic form of the thyroid hormone T3 and is delivered through the skin via a transdermal gel.

How should I use this transdermal gel?

This transdermal gel is applied directly to the skin. The pump mechanism dispenses a measured dose of the gel, which you should spread thinly over the area of skin as directed by your healthcare provider. Do not cover the area with bandages or dressings unless instructed to do so.

How often do I need to apply Liothyronine Transdermal Gel?

The frequency of application will be determined by your prescriber based on your individual treatment needs. Follow the dosing instructions provided by your healthcare provider or pharmacist.

What are the advantages of using a transdermal gel for medication?

A transdermal gel allows medication to be absorbed directly through the skin, which can provide a steady release of the active ingredient into the bloodstream. This method may reduce the likelihood of systemic side effects compared to oral medications and can be beneficial for patients who have difficulties with oral administration.

Where on my body should I apply the gel?

Your healthcare provider will advise you on the most appropriate application site(s) for the gel. Common areas include the inner wrists, arms, or thighs. It is important to rotate the application sites to prevent skin irritation.

Can I shower or swim after applying the gel?

It is best to wait for a certain amount of time, typically 1 to 2 hours, after applying the gel before showering or swimming to ensure proper absorption. Your pharmacist or healthcare provider can give you specific instructions regarding your situation.

What should I do if I miss a dose?

If you miss a dose of Liothyronine Transdermal Gel, apply it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and return to your regular dosing schedule. Do not double doses to catch up.

Are there any side effects associated with Liothyronine Transdermal Gel?

As with any medication, side effects may occur. Common side effects can include skin irritation at the application site, itching, or rash. More serious side effects may include symptoms of hyperthyroidism such as sweating, rapid heartbeat, nervousness, or insomnia. Contact your healthcare provider if you experience any severe or concerning symptoms.

How should I store the medication?

Store the gel at room temperature away from direct sunlight and heat. Do not freeze. Keep the container tightly closed when not in use and keep the medication out of reach of children and pets.

Can I use other skin products on the same area where I've applied the gel?

It is generally recommended to avoid using other skin products, such as lotions or creams, on the same area where you've applied the thyroid gel to prevent alteration of the medication's absorption. Discuss with your pharmacist about the appropriate timing for the use of other skin products.

What should I do if I accidentally get the gel in my eyes or mouth?

If the medication comes into contact with your eyes or mouth, rinse the area thoroughly with water. While the medication is intended for topical use only, incidental contact with eyes or mouth should be non-hazardous, but it's always best to consult your healthcare provider or seek medical attention if you are concerned about exposure.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.