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Formulas

Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream

The Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream is a specialized semisolid preparation that combines two potent local anesthetics. This cream is specifically formulated for topical use and is dispensed through a pump mechanism, which allows for convenient and controlled application. The dual anesthetic action of lidocaine and tetracaine provides effective localized relief from pain and discomfort.

This formulation is primarily used to treat conditions that benefit from topical anesthesia, such as minor skin irritations, insect bites, and localized pain from conditions like neuropathy. It is also utilized in procedures that require skin numbing, such as needle insertions, minor surgical interventions, and aesthetic treatments like laser hair removal or tattoo application. The cream's transdermal delivery system ensures that the active ingredients are absorbed into the skin for targeted action, providing patients with rapid and effective relief from the treated disease states.

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Topical Cream
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Formula Information

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Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream is a compounded medication specifically designed to deliver a combination of two local anesthetics through the skin for the purpose of providing localized pain relief. Lidocaine and Tetracaine are both amide-type local anesthetics that work by blocking sodium channels, which are necessary for the initiation and conduction of neuronal impulses. When applied topically, this combination can lead to a synergistic effect, enhancing the overall numbing action and providing effective analgesia for various conditions.

The semisolid preparation of this transdermal cream is formulated to ensure a consistent and uniform dose with each application. The pump mechanism is particularly beneficial for patients and caregivers, as it allows for easy, mess-free application and minimizes the risk of contamination. The cream is designed to be absorbed through the skin, delivering the active ingredients directly to the site of pain or discomfort.

This formulation is commonly used for the management of localized pain, including but not limited to, neuropathic pain, chronic pain conditions, and pain associated with minor surgical procedures or skin irritations. It may also be used as a pre-procedural anesthetic to numb the skin before certain medical procedures such as injections, intravenous cannulation, or minor dermatological treatments. The dual action of Lidocaine and Tetracaine provides a rapid onset of anesthesia with a prolonged duration of action, making it a versatile option for both acute and chronic pain management.

Patients and prescribers should be aware that the use of this cream should be limited to the prescribed area and duration, as excessive application can lead to systemic absorption and potential adverse effects. It is also important to consider the patient's medical history, including any known allergies to local anesthetics or other components of the cream. As with any compounded medication, this formulation is made to order and can be tailored to meet the specific needs of the patient.

For those interested in utilizing Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream, or for more detailed information regarding its use, potential side effects, contraindications, and compatibility with other medications, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is dedicated to providing the highest quality of care and is available to answer any questions or concerns you may have about this specialized medication.

Drug Interactions

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The Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream is a topical anesthetic formulation designed to provide localized relief from pain and discomfort by numbing the skin and underlying tissues. This combination of two local anesthetics, lidocaine and tetracaine, works by blocking the nerve signals in the body, which helps to reduce pain sensation in the area where the cream is applied. It is commonly used for procedures that require skin anesthesia, such as minor surgical interventions, needle insertions, and superficial dermatological procedures.

When considering the use of this transdermal cream, it is important to be aware of potential drug interactions. Both lidocaine and tetracaine are metabolized by the liver, and drugs that affect liver enzymes could potentially alter the metabolism of these anesthetics. For example, certain anti-seizure medications, such as phenytoin, and some antibiotics, like erythromycin, may affect the metabolism of lidocaine and tetracaine, potentially leading to increased levels of the anesthetics in the blood and an increased risk of systemic toxicity.

Additionally, the use of other local anesthetics concurrently with this formulation should be approached with caution, as the additive systemic effects could increase the risk of toxicity. Patients taking class III antiarrhythmic drugs, such as amiodarone, should also be monitored closely, as these medications can potentiate the effects of lidocaine and tetracaine, potentially leading to cardiac side effects.

Patients with a history of methemoglobinemia, a condition where the blood is unable to carry oxygen effectively, should use this cream with caution, as both lidocaine and tetracaine can exacerbate this condition. Drugs that induce methemoglobinemia, such as nitrates and certain antibiotics, should be used with caution in patients receiving this transdermal cream.

It is also important to consider the impact of this formulation on patients taking other medications that depress the central nervous system (CNS), such as opioids, sedatives, or anxiolytics. The concurrent use of these medications with lidocaine and tetracaine may increase CNS depression, leading to additional sedative effects.

Lastly, because this formulation is applied topically, it is important to consider the potential for interaction with other topical medications. The use of other topical agents on the same area of skin may alter the absorption or effectiveness of the anesthetics.

Patients should be advised to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs, herbal supplements, and any other topical products. Prescribers should review the patient's medication history to assess for potential interactions and adjust treatment as necessary. If you have any questions or require further information regarding drug interactions with the Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream, please reach out to us at Bayview Pharmacy for assistance.

How Does it Work

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The Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream is a topical anesthetic formulation designed to provide localized pain relief and numbness to the skin and underlying tissues. This cream combines two potent local anesthetics, lidocaine and tetracaine, both of which work by blocking sodium channels in the neuronal cell membrane. When applied to the skin, these active ingredients prevent the initiation and conduction of nerve impulses, thereby providing analgesic and anesthetic effects.

Lidocaine, chemically known as lidocaine hydrochloride, is a well-known amide local anesthetic that has a rapid onset of action and intermediate duration of efficacy. It is commonly used for various procedures that require numbing of the skin and mucous membranes. Tetracaine, also known as tetracaine hydrochloride, is an ester local anesthetic that has a slower onset but a longer duration of action compared to lidocaine. When combined, these two anesthetics offer a synergistic effect, providing both immediate and prolonged pain relief, which can be particularly beneficial for procedures that require extended periods of anesthesia.

The transdermal cream is formulated to facilitate the penetration of the active ingredients through the skin. It is dispensed in a pump mechanism, which allows for a controlled and consistent dose with each application. This dosage form is convenient for patients, as it minimizes the mess and variability associated with traditional tube or jar packaging. The semisolid preparation is designed to be easily spreadable and absorbed into the skin without leaving a greasy residue.

This combination of lidocaine and tetracaine in a transdermal cream is particularly useful for treating localized pain conditions such as minor burns, insect bites, and needle insertions. It can also be used for superficial surgical procedures, such as skin biopsies or laser treatments, where pain relief is required on a specific area of the skin. The cream's formulation allows for targeted application, reducing the risk of systemic side effects and providing a safer option for patients who require localized anesthesia.

For patients and prescribers considering the use of Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream, it is important to understand the proper application technique and the potential for adverse reactions, although they are generally rare when the cream is used as directed. As with any medication, it is crucial to follow the prescribed instructions and to consult with a healthcare professional if there are any concerns or questions regarding its use. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance you need to ensure safe and effective treatment.

Other Uses

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The Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream formulation is primarily designed to provide topical anesthesia for various minor medical procedures and to alleviate localized pain. However, it can have other off-label or ancillary uses due to its constituents' pharmacological properties. For example, this cream may be employed to temporarily relieve the pain associated with conditions like post-herpetic neuralgia, which is the pain that continues after a shingles rash has cleared. It is also sometimes used in the management of superficial skin processes that may be painful, such as tattoo application or removal, laser hair removal, or superficial dermatological procedures that do not require deep anesthesia.

Beyond dermatological use, the anesthetic properties of this cream could be useful in the symptomatic relief of anorectal disorders such as hemorrhoids, where the application may help ease discomfort during bowel movements by providing temporary anesthesia to the affected area. It's important to note, however, that while the cream may aid in symptomatic relief, it is not a treatment for the underlying causes of these conditions. Providers may also consider this formulation for use with needle insertion, whether for IV starts or other injections, to minimize pain at the insertion site.

It is essential for both patients and prescribers to recognize that while the Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream can be beneficial for multiple scenarios, careful consideration is required regarding its application due to the potency of the anesthetic agents involved. The vehicle of this cream—a semisolid preparation dispensed in a pump mechanism—allows for controlled and metered dosage, which is crucial in minimizing the risk of systemic absorption leading to toxicity. Users should be advised to apply the cream only to intact skin and follow instructions for use meticulously, particularly in terms of the amount used and the area of application.

Caution should also be exercised when applying to large areas or when applying heat or occlusive dressings, as these situations can increase systemic absorption of local anesthetics. Additionally, patients with a history of cardiac, liver, or kidney disorders or those who are on concurrent medications that affect drug metabolism may require special consideration and dosing adjustments. Furthermore, it is important for patients to report any past allergic reactions to local anesthetics before using this product.

In conclusion, while the Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream is valuable for its intended uses, its role in managing other types of pain or as an adjuvant in various minor procedures should be explored with caution and clinical judgement. If you have questions regarding this formulation's broader applications or need advice tailored to a specific clinical situation, please reach out to us at Bayview Pharmacy for professional guidance.

Frequently Asked Questions

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What is Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream used for?

This compounded transdermal cream is used for the localized relief of pain by numbing the skin in the area where it's applied. It is typically prescribed for various conditions requiring topical anesthesia or pain relief.

How should I apply this transdermal cream?

Clean and dry the area of skin where you will apply the cream. Use the pump to dispense the cream and apply a thin layer over the area, following your healthcare professional's instructions regarding dosage and frequency. Do not rub in the cream.

Can Lidocaine/Tetracaine cream be used for chronic pain conditions?

While it is primarily designed for temporary relief of pain, your healthcare provider may prescribe it for managing symptoms associated with chronic pain conditions. Always use the cream as directed by your healthcare provider.

Is it safe to cover the area with a bandage after applying the cream?

It is generally recommended not to cover the treated area with a bandage or wrap unless instructed by your doctor, as this may increase the absorption of the medication and raise the risk of side effects.

Can I use this cream on open wounds or damaged skin?

No, do not apply this cream to open wounds, burns, or irritated skin. It is intended for use on intact skin only to alleviate localized pain.

What should I do if I miss a dose of the cream?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and apply the next one at the regular time. Do not apply extra cream to make up for a missed dose.

Are there any side effects of using Lidocaine/Tetracaine Transdermal Cream?

Possible side effects may include mild skin reactions such as redness, itching, or burning at the application site. If you experience any severe reactions or symptoms such as difficulty breathing, swelling, hives, or dizziness, seek medical attention immediately.

How should this cream be stored?

Store the cream at room temperature away from heat and moisture. Keep it out of reach of children and pets, and do not freeze the medication.

Can I use this cream if I am pregnant or breastfeeding?

Consult your healthcare provider before using this cream if you are pregnant or breastfeeding. Your provider will be able to determine if this medication is safe for you based on your specific circumstances.

How does the pump mechanism of the transdermal cream work?

The pump mechanism is designed to dispense a controlled amount of cream with each press. This feature allows for consistent and hygienic application while minimizing the chance of contamination.

Can I use other medications or topical treatments with this cream?

It is important to discuss the use of other medications or topical treatments with your healthcare provider to prevent any potential interactions. Always inform your healthcare provider of all the products you are using before starting treatment with Lidocaine HCl 7%/Tetracaine HCl 7% Transdermal Cream.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.