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Formulas

Lidocaine HCl 10% Topical Cream

The Lidocaine HCl 10% Topical Cream is a semisolid preparation formulated for the temporary relief of pain and discomfort associated with conditions such as minor burns, insect bites, minor cuts, and scrapes. This cream is also used to alleviate the itching and pain from skin irritations, and it can be beneficial in the treatment of localized neuropathic pain or postherpetic neuralgia. The cream is dispensed in a pump mechanism, which allows for convenient and controlled application, ensuring that the lidocaine is delivered directly to the affected area for targeted relief.

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Lidocaine Hydrochloride
Topical Cream
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Formula Information

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Lidocaine HCl 10% Topical Cream is a highly concentrated local anesthetic formulation intended for topical application. The active ingredient, Lidocaine Hydrochloride, is a well-known amide-type local anesthetic that provides rapid numbing effects when applied to the skin. This particular cream is designed to deliver the anesthetic effect directly to the site of discomfort, making it an ideal choice for localized pain relief, minor skin irritations, superficial cuts, and abrasions, as well as for certain types of neuropathic pain. The 10% concentration ensures a potent dose, which can be particularly beneficial for more intense or persistent pain symptoms.

The cream is compounded into a semisolid preparation, which allows for a smooth and even application over the affected area. The inclusion of a pump mechanism in the packaging is a deliberate choice to enhance patient convenience, hygiene, and dosing accuracy. Each pump dispenses a measured amount of cream, reducing the risk of over-application and ensuring consistent dosing. This feature is especially useful for patients who may have difficulty with manual dexterity or for those who require a precise amount of medication for effective treatment.

When applied to the skin, Lidocaine HCl works by blocking sodium channels, which are essential for the conduction of nerve impulses. By inhibiting these channels, Lidocaine HCl prevents the initiation and transmission of pain signals, thereby providing local analgesia. This action makes it an effective treatment for a variety of dermatological conditions that involve pain or discomfort. It is important to note that while Lidocaine HCl 10% Topical Cream is effective for localized pain relief, it is not suitable for all types of pain and should not be used on large areas of the body or for prolonged periods without consulting a healthcare professional.

Patients and prescribers should be aware that while Lidocaine HCl is generally well-tolerated, there are potential side effects, such as skin irritation or allergic reactions, which should be monitored. Additionally, the cream should be used with caution in patients with a history of cardiac conditions or those taking certain medications that may interact with local anesthetics. It is also important to ensure that the cream is applied only to intact skin and not to open wounds or mucous membranes.

For those interested in using Lidocaine HCl 10% Topical Cream, or for healthcare providers considering prescribing this formulation, Bayview Pharmacy is available to answer any questions and provide further information. Our team of compounding pharmacists is dedicated to ensuring that each patient receives the most appropriate and effective treatment for their specific needs. Please feel free to reach out to us for guidance on the use of this formulation or to discuss any concerns regarding its application and potential benefits in treating localized pain and discomfort.

Drug Interactions

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Lidocaine HCl 10% Topical Cream is a local anesthetic used to provide temporary relief of pain and itching associated with minor burns, skin irritations, insect bites, and anorectal disorders. When considering the use of this formulation, it is important to be aware of potential drug interactions that may affect its efficacy or increase the risk of adverse effects.

While topical lidocaine has minimal systemic absorption, interactions can still occur, particularly with other local anesthetics or medications that affect cardiac conduction. Concurrent use of other local anesthetics or medications with similar pharmacological effects should be approached with caution, as the systemic absorption of lidocaine may be increased, potentially leading to additive systemic toxicity. This is especially relevant in patients with pre-existing cardiac conditions, as lidocaine can have cardiodepressant effects.

Patients using antiarrhythmic drugs, such as mexiletine or tocainide, which are structurally similar to lidocaine, may experience increased risk of adverse effects due to additive cardiac effects. It is advisable to monitor cardiac function when these drugs are used concurrently. Additionally, the use of lidocaine with Class III antiarrhythmics (e.g., amiodarone) may increase the risk of QT prolongation, which can lead to serious cardiac arrhythmias.

Enzyme inducers or inhibitors can also affect lidocaine metabolism. Drugs that inhibit cytochrome P450 3A4 (CYP3A4) enzymes, such as ketoconazole, itraconazole, and some protease inhibitors, may decrease the metabolism of lidocaine, leading to increased plasma concentrations and potential toxicity. Conversely, enzyme inducers like phenytoin, phenobarbital, and rifampin may increase the metabolism of lidocaine, reducing its efficacy.

Caution is also advised when using lidocaine in patients taking beta-blockers, as there may be an increased risk of bradycardia. Additionally, the concomitant use of lidocaine with cimetidine, a CYP3A4 inhibitor, may lead to increased lidocaine plasma levels, necessitating close monitoring for signs of toxicity.

It is important to note that the application of lidocaine to large surface areas or over prolonged periods, especially under occlusive dressings, can increase systemic absorption and the risk of systemic side effects. Patients should be advised to use the smallest effective amount for the shortest duration necessary to minimize the risk of systemic exposure.

Patients should always inform their healthcare provider of all medications they are taking, including over-the-counter drugs, herbal supplements, and vitamins, to ensure that potential interactions with lidocaine HCl 10% Topical Cream are assessed and managed appropriately. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Lidocaine HCl 10% Topical Cream is a local anesthetic formulation that works by temporarily numbing the skin and surrounding tissues where it is applied. The active ingredient, Lidocaine Hydrochloride, is a well-known amide-type local anesthetic that provides rapid onset and medium duration of action. When applied to the skin, lidocaine blocks the sodium channels located on the neuronal cell membranes. This action inhibits the initiation and conduction of nerve impulses, thereby providing local anesthetic effects.

The cream is specifically designed to be dispensed in a pump mechanism, which allows for a controlled and hygienic delivery of the medication. This method of dispensing ensures that the patient receives a consistent dose of the medication with each application, which is important for maintaining the effectiveness of the treatment. The semisolid preparation of the cream allows for easy application and adherence to the skin, ensuring that the active ingredient remains in contact with the treatment area for an adequate period of time to exert its therapeutic effect.

Lidocaine HCl 10% Topical Cream is used to treat a variety of disease states that require localized pain relief. It is commonly used for the relief of pain associated with minor skin irritations, lacerations, abrasions, and burns. It is also used in the management of more chronic conditions such as postherpetic neuralgia, which is a painful condition that can occur after an outbreak of shingles. Additionally, this formulation can be used to numb the skin prior to certain medical procedures, such as needle insertions, to reduce the discomfort experienced by the patient.

For patients, it is important to apply the cream as directed by a healthcare professional and to ensure that the area of application is clean and dry to maximize the absorption of the active ingredient. For prescribers, it is essential to consider the patient's medical history, including any known allergies to local anesthetics, before recommending this formulation. The use of lidocaine cream should be monitored, especially in patients with hepatic or cardiac conditions, as systemic absorption, although minimal, can occur and may have potential effects on these systems.

If you have any questions about the Lidocaine HCl 10% Topical Cream or its application, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively use this formulation for the treatment of localized pain and discomfort.

Other Uses

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Lidocaine HCl 10% Topical Cream, beyond its primary indication for providing local anesthesia and relief from itching or pain due to skin conditions, can serve several off-label or less commonly known purposes. One alternative use of this formulation is for the treatment of post-herpetic neuralgia, a condition characterized by nerve pain following a shingles infection. This high-concentration lidocaine preparation can help to manage the neuropathic pain by numbing the affected area. Some patients may also experience relief from other forms of neuropathy or neuralgia when using this cream, though it's always crucial to consult with a healthcare provider before applying it for these conditions.

In addition, this formulation has been beneficial for individuals undergoing procedures involving needle insertions, such as IV placement or blood draws, especially for those with a pronounced fear of needles or a low pain threshold. The cream serves to desensitize the area, thereby reducing the discomfort associated with such procedures. Furthermore, some patients with chronic painful conditions like tendinitis or bursitis have reported symptomatic relief when using this lidocaine cream. Although it is not a cure for underlying inflammation, it may provide temporary relief from the pain associated with these conditions.

Another potential application is the use before certain dermatological procedures. For example, it can be utilized to numb the skin prior to laser treatment, tattoo application, or removal, and even before administering cosmetic injectables. The goal here is to ensure patient comfort and lessen the pain that may occur during these procedures. Additionally, there might be a benefit for individuals with specific painful lesions of the mucous membranes, although caution is advised, and use in mucosal tissues should only be under direct medical supervision due to increased absorption and risk of systemic toxicity.

It is essential to note that while Lidocaine HCl 10% Topical Cream can be helpful for a variety of applications, each patient's situation is unique, and it is not suitable for every condition or person. The likelihood of systemic absorption and subsequent toxicity must be taken into account, especially in patients with pre-existing cardiac or liver conditions. Moreover, the formulation should be used with careful consideration in children or individuals with lower body weight, and not all off-label uses are equally supported by scientific evidence. Always consult with a healthcare professional before using this product for any unlisted condition or purpose.

As compounding pharmacists at Bayview Pharmacy, we are dedicated to providing our patients and prescribers with comprehensive and personalized information about our products. If you have any questions regarding the use of Lidocaine HCl 10% Topical Cream for applications other than those primarily intended or if you need more detailed information about potential off-label uses and associated precautions, please reach out to us. We are here to ensure your safety and the efficacy of your treatment.

Frequently Asked Questions

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What is Lidocaine HCl 10% Topical Cream used for?

Lidocaine HCl 10% Topical Cream is used for providing temporary relief of pain and numbness in the skin. It is often used for procedures that involve needle insertion, skin surface anesthesia, and for the relief of minor skin discomforts.

How do I use Lidocaine HCl 10% Topical Cream?

To use the cream, apply a thin layer to the affected area of the skin as directed by your healthcare provider. The pump mechanism allows for controlled dosage. Avoid applying to broken or irritated skin, and do not use in larger amounts or for longer than recommended.

How often can I apply Lidocaine HCl 10% Topical Cream?

Follow your healthcare provider's instructions regarding the frequency of application, as it can vary depending on the condition being treated. Do not use more often than prescribed.

Can Lidocaine HCl 10% Topical Cream be used for all age groups?

No, not necessarily. Always check with a healthcare provider before using Lidocaine HCl 10% Topical Cream, especially in children and the elderly, as they may have different dosing requirements and sensitivities.

What are the side effects of Lidocaine HCl 10% Topical Cream?

Common side effects may include mild skin irritation, redness, or swelling at the application site. If you experience severe side effects such as difficulty breathing, hives, or dizziness, seek medical attention immediately.

Can I cover the treated skin area after applying Lidocaine HCl 10% Topical Cream?

You should not cover the treated skin area unless your healthcare provider tells you to do so. Covering the area can increase the absorption of the medication, which could lead to unwanted side effects.

How should I store Lidocaine HCl 10% Topical Cream?

Store the cream at room temperature away from moisture and heat. Do not freeze the cream, and keep it out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular application schedule. Do not apply extra cream to make up for a missed dose.

Can I use Lidocaine HCl 10% Topical Cream with other topical medications?

It's important to discuss with your healthcare provider before using other topical medications in conjunction with Lidocaine HCl 10% Topical Cream, as there may be interactions or increased risk of side effects.

What should I avoid while using Lidocaine HCl 10% Topical Cream?

Avoid getting Lidocaine HCl 10% Topical Cream in your eyes, nose, or mouth. If this happens, rinse with water immediately. Also, avoid using heat sources such as heating pads or electric blankets on the area where the cream has been applied as it may enhance absorption and increase the risk of side effects.

Is Lidocaine HCl 10% Topical Cream safe during pregnancy or breastfeeding?

Consult your healthcare provider before using Lidocaine HCl 10% Topical Cream if you are pregnant or breastfeeding. Your healthcare provider will determine if the medication is safe for you based on your specific circumstances.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.