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Formulas

Lidocaine 7%/Tetracaine 7% Topical Gel

The Lidocaine 7%/Tetracaine 7% Topical Gel is a semisolid anesthetic formulation designed for external use. This gel is dispensed through a pump mechanism, which allows for easy and precise application to the skin. The combination of lidocaine and tetracaine in a gel-like consistency ensures targeted treatment and effective absorption of the active ingredients.

This topical anesthetic is primarily used to numb the skin in preparation for minor medical procedures, such as needle insertions, IV starts, and superficial surgical interventions. It is also employed to provide temporary relief from pain associated with conditions like postherpetic neuralgia or other neuropathic pain states. Additionally, the gel may be used to alleviate discomfort from skin irritations, minor burns, insect bites, and sunburns.

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Topical Gel
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Formula Information

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Lidocaine 7%/Tetracaine 7% Topical Gel is a compounded medication designed to provide local anesthesia by numbing specific areas of the skin. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application. The gel-like consistency ensures that the medication stays in place on the skin, providing targeted treatment and facilitating the absorption of the active ingredients, lidocaine and tetracaine.

Lidocaine and tetracaine are both local anesthetics that work by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect. When applied topically, this combination can be used for a variety of procedures that require local anesthesia, such as minor surgical procedures, laser treatments, or as part of a pain management protocol for conditions like neuropathic pain or chronic pain syndromes.

The 7% concentration of each active ingredient in this formulation is chosen to provide a potent anesthetic effect while minimizing the risk of systemic toxicity. The gel base offers an advantage over ointments or creams by creating a more favorable environment for the anesthetic to penetrate the skin. Additionally, the pump dispenser ensures that the medication is administered in a controlled manner, reducing the risk of applying too much or too little of the product.

Patients and prescribers should be aware that the use of Lidocaine 7%/Tetracaine 7% Topical Gel may be associated with local reactions such as erythema, edema, or an abnormal sensation at the site of application. Systemic adverse effects are rare but can occur if the medication is applied over a large area of skin, used for prolonged periods, or if the skin barrier is compromised. It is important to follow the prescribed dosing instructions and to use the medication only on the area of skin that requires treatment.

For prescribers, it is crucial to consider the patient's overall health status, including any pre-existing conditions or concurrent medications that may interact with local anesthetics. Prescribers should also counsel patients on the proper use of the medication, including how to operate the pump dispenser and the importance of adhering to the recommended application area and frequency.

Bayview Pharmacy is committed to providing high-quality compounded medications tailored to the specific needs of patients. Our team of knowledgeable compounding pharmacists is available to answer any questions or concerns regarding the Lidocaine 7%/Tetracaine 7% Topical Gel formulation. If you have any questions or require further information, please do not hesitate to reach out to us.

Drug Interactions

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The Lidocaine 7%/Tetracaine 7% Topical Gel is a combination anesthetic formulation designed for topical application. Lidocaine and tetracaine are both local anesthetics that work by blocking nerve signals in the body, which helps to numb the topical area. This formulation is commonly used for procedures that require local anesthesia of the skin, such as minor surgical procedures, laser treatments, or as part of a pain management strategy for certain skin conditions.

When considering the use of Lidocaine 7%/Tetracaine 7% Topical Gel, it is important to be aware of potential drug interactions. Both lidocaine and tetracaine are metabolized by the liver, and drugs that affect liver enzymes could potentially alter the metabolism of these anesthetics. For example, certain anti-seizure medications, such as phenytoin, and some antibiotics, like erythromycin, can affect liver enzyme activity and potentially increase the levels of lidocaine and tetracaine in the body, leading to an increased risk of systemic toxicity.

Concomitant use of other local anesthetics or medications with a similar mechanism of action should be approached with caution, as the additive effects could increase the risk of systemic toxicity, including central nervous system and cardiovascular effects. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

Patients with heart conditions, especially those taking anti-arrhythmic drugs such as amiodarone or beta-blockers, should use this formulation with caution, as the systemic absorption of lidocaine and tetracaine could have additive effects on the heart, potentially leading to arrhythmias or other cardiac events.

Additionally, the use of this topical gel in conjunction with other medications that can cause methemoglobinemia, such as sulfonamides, acetaminophen, and nitrates, should be monitored closely. Lidocaine and tetracaine can induce methemoglobinemia, a condition where the oxygen-carrying capacity of the blood is reduced, and combining these drugs can increase this risk.

It is also important to note that the application of this gel to very large areas of skin, broken or inflamed skin, or its use under occlusive dressings could increase systemic absorption and the potential for drug interactions. Therefore, the amount of gel used and the condition of the skin should be taken into consideration when assessing the risk of interactions.

Patients should avoid applying other topical products to the same area where the Lidocaine 7%/Tetracaine 7% Topical Gel is used unless directed by a healthcare provider, as there may be interactions at the site of application that could alter the effectiveness of the gel or the concomitant product.

In summary, while Lidocaine 7%/Tetracaine 7% Topical Gel is applied topically and generally has minimal systemic absorption, there is still a potential for drug interactions, particularly with medications that affect liver enzymes, other local anesthetics, heart medications, and drugs that increase the risk of methemoglobinemia. Healthcare providers should review a patient's medication history for potential interactions before prescribing this formulation. Patients should be advised to report any unusual symptoms or adverse reactions promptly. If you have any questions or require further information regarding drug interactions with this formulation, please reach out to us at Bayview Pharmacy.

How Does it Work

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The Lidocaine 7%/Tetracaine 7% Topical Gel is a compounded medication designed to provide localized relief from pain by combining the anesthetic effects of both lidocaine and tetracaine. Lidocaine and tetracaine are both amide-type local anesthetics that work by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect on the applied area. When applied topically, this gel formulation allows for the anesthetics to penetrate the skin and reach the underlying tissues where they exert their effect.

The semisolid gel formulation is specifically designed to be dispensed through a pump mechanism. This delivery system offers several advantages, including the ability to provide a consistent dose with each pump, minimizing waste and ensuring that the correct amount of medication is applied to the affected area. The gel base facilitates easy application and allows the active ingredients to remain on the skin's surface for an extended period, enhancing the absorption and increasing the duration of the anesthetic effect.

This compounded gel is particularly useful in treating various disease states that involve pain or the need for localized anesthesia. For instance, it can be used for procedures such as laser hair removal, tattoo application and removal, and minor skin surgeries where surface anesthesia is required. Additionally, it may be beneficial for patients experiencing chronic pain conditions like neuropathies or certain types of dermatological pain syndromes, where a topical anesthetic can provide targeted relief without the systemic side effects associated with oral pain medications.

It is important for both patients and prescribers to understand that while this formulation provides significant pain relief, it should be used with caution. The application area must be limited to avoid systemic absorption that could lead to toxicity, and it should not be applied to broken or irritated skin. The duration of application should also be monitored to prevent excessive absorption and potential adverse effects. As with any compounded medication, this formulation should be used under the guidance of a healthcare professional who can tailor the treatment to the specific needs of the patient.

If you have any questions about the Lidocaine 7%/Tetracaine 7% Topical Gel or its appropriate use for different disease states, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure safe and effective treatment outcomes.

Other Uses

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The Lidocaine 7%/Tetracaine 7% Topical Gel compounded at Bayview Pharmacy extends beyond the commonly recognized uses in dermatological and minor surgical procedures. This combination of local anesthetics is traditionally utilized to numb the skin to provide temporary relief of pain and discomfort associated with conditions such as minor burns, insect bites, and needle insertions. However, it is also found to be advantageous in other clinical situations.

Patients receiving cosmetic or aesthetic procedures, such as laser hair removal, microneedling, or tattoo application and removal, may also benefit from the numbing effect of Lidocaine/Tetracaine gel. Its anesthetic properties can considerably reduce discomfort during these often painful experiences, thus improving patient tolerance and satisfaction. In the field of podiatry, the gel is often applied before procedures to alleviate pain associated with toenail removal, callus treatments, or injection administration.

Furthermore, the gel may assist in pain management for patients undergoing various types of diagnostic interventions like mammographies where skin compression can cause discomfort. Individuals with chronic conditions like neuropathic pain or fibromyalgia have occasionally found symptomatic relief upon using the gel on painful skin areas. In sports medicine, the formulation could be employed to temporarily relieve muscle or joint pain resulting from minor injuries, as long as it does not delay the diagnosis or treatment of any underlying condition.

It is important to note that while this Lidocaine/Tetracaine gel provides topical analgesia, it is not suitable for all types of pain and should not be used on large areas of skin or on open wounds. Its use should be limited to intact skin surfaces. Patients and prescribers are reminded to use this product as directed and to consider all potential contraindications and the pharmacologic profiles of both lidocaine and tetracaine when considering other uses. As with any medication, the potential for allergic reaction exists, and proper testing should be done prior to application on larger skin areas.

For more customized guidance and to discuss the potential benefits and risks associated with this formulation for alternative uses, please reach out to our compounding pharmacy team at Bayview Pharmacy. We are here to provide you with the information and support you need to make informed choices about your care or the care of your patients.

Frequently Asked Questions

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What is Lidocaine 7%/Tetracaine 7% Topical Gel used for?

Lidocaine 7%/Tetracaine 7% Topical Gel is used as a topical anesthetic to numb the skin prior to certain medical procedures, such as injections, intravenous (IV) insertions, and minor surgical procedures. It can also be used to relieve superficial pain on the skin surface.

How do you apply Lidocaine 7%/Tetracaine 7% Topical Gel?

Before applying the gel, clean and dry the affected area. Apply a thin layer of the gel to the skin as directed by your healthcare provider. Use the pump mechanism to dispense the correct amount of gel needed, and gently spread the gel onto the skin without rubbing it in. Always follow the specific instructions provided by your healthcare professional or included with the product packaging.

How long does it take for Lidocaine 7%/Tetracaine 7% Topical Gel to work?

The onset of numbness generally occurs within 20 to 30 minutes after application. However, the exact time may vary depending on the thickness of the skin and other individual factors. Consult the product label or ask your healthcare provider for more information regarding the onset of action.

How often can I use Lidocaine 7%/Tetracaine 7% Topical Gel?

The frequency of application for Lidocaine 7%/Tetracaine 7% Topical Gel should be determined by your healthcare provider. Do not apply the gel more often than prescribed as this could increase the risk of side effects.

Can Lidocaine 7%/Tetracaine 7% Topical Gel be used on open wounds?

No, Lidocaine 7%/Tetracaine 7% Topical Gel should not be used on open wounds or damaged skin. It is only meant for use on intact skin. Consult your healthcare provider for alternatives if you need anesthetic treatment for an open wound.

Should I cover the area after applying Lidocaine 7%/Tetracaine 7% Topical Gel?

It is generally not necessary to cover the treated area unless instructed by a healthcare provider. If an occlusive dressing is recommended, follow the specific instructions given to you with regard to the duration and method of covering.

What should I do if I experience any adverse reactions to Lidocaine 7%/Tetracaine 7% Topical Gel?

If you experience any adverse reactions such as itching, redness, swelling, or prolonged numbness beyond the treatment area, stop using the gel and contact your healthcare provider immediately. In the case of severe reactions, seek emergency medical attention.

Is Lidocaine 7%/Tetracaine 7% Topical Gel safe for children?

Use of Lidocaine 7%/Tetracaine 7% Topical Gel in children should be under the supervision of a healthcare provider, as children may have a heightened sensitivity to the active ingredients. Follow the guidance of your child's physician regarding use and dose.

Can I use Lidocaine 7%/Tetracaine 7% Topical Gel if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult your healthcare provider before using Lidocaine 7%/Tetracaine 7% Topical Gel. Your doctor will assess the benefits and possible risks associated with its use during pregnancy or while breastfeeding.

How should I store Lidocaine 7%/Tetracaine 7% Topical Gel?

Store Lidocaine 7%/Tetracaine 7% Topical Gel at room temperature away from direct sunlight and heat. Keep the cap tightly closed when not in use. Keep it out of reach of children and pets. Consult the product packaging or ask your pharmacist for specific storage instructions if necessary.

Can I apply makeup or sunscreen over Lidocaine 7%/Tetracaine 7% Topical Gel?

It is generally recommended to avoid applying makeup or sunscreen over the area where the gel has been applied until the numbness has worn off, as you may accidentally injure the numbed skin. If your healthcare provider approves the application of other products over the treated area, ensure that the gel has fully dried first.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.