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Lidocaine 20%/Ketoprofen 20% Topical Ointment

The Lidocaine 20%/Ketoprofen 20% Topical Ointment is a semi-solid formulation intended for external application to the skin. This ointment is dispensed in a tube and possesses a greasy or oily base, which facilitates the localized delivery of its active ingredients. Lidocaine, a local anesthetic, provides temporary relief from pain by numbing the treated area. Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), works by reducing inflammation and pain in the affected area.

This combination ointment is specifically designed to treat a variety of disease states, including localized musculoskeletal pain, soft tissue injuries, and inflammatory skin conditions. The dual action of Lidocaine and Ketoprofen offers both immediate pain relief and longer-term anti-inflammatory benefits, making it an effective treatment option for patients seeking targeted symptom management.

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Ketoprofen
Lidocaine Hydrochloride
Topical Ointment
65b03bd856c3843dcde4ffc5
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Formula Information

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Lidocaine 20%/Ketoprofen 20% Topical Ointment is a compounded medication specifically designed for external application to the skin. This semi-solid formulation is dispensed in a tube and provides a greasy or oily base, which not only facilitates the application but also enhances the penetration of the active ingredients into the skin. The ointment is intended for localized treatment and is particularly useful in managing conditions that involve pain and inflammation.

Lidocaine, a local anesthetic, works by blocking sodium channels and thereby reducing the sensation of pain. When applied topically, it can provide significant relief from localized pain without the systemic side effects associated with oral pain medications. This makes it an excellent choice for targeted pain management, especially in patients who may be sensitive to systemic analgesics or those who prefer a localized approach to pain relief.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that exerts its effect by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins. Prostaglandins are mediators of inflammation and pain. By reducing their production, ketoprofen effectively decreases inflammation and associated pain. This makes the ointment particularly beneficial for inflammatory skin conditions, such as dermatitis, or musculoskeletal issues like sprains and strains where inflammation is a key component of the pathology.

The combination of lidocaine and ketoprofen in a 20% concentration for each provides a potent dual-action effect for the management of pain and inflammation. The ointment is typically applied to the affected area two to three times daily, or as directed by a healthcare provider. It is important to note that this medication should be used on intact skin and not applied to open wounds or damaged skin. Patients should also be advised to wash their hands before and after applying the ointment unless the hands are the treated area.

As with any medication, there are potential side effects, and patients should be counseled on what to expect and when to seek medical attention. Common side effects may include local skin reactions such as redness, itching, or irritation at the site of application. More serious side effects are rare but can occur, especially with prolonged use or if the ointment is applied over large areas of the body.

It is essential for prescribers to consider the patient's overall medical history, including any known allergies to lidocaine, ketoprofen, or other NSAIDs, and to assess for potential drug interactions. Additionally, prescribers should adjust the dosage and frequency as necessary based on the patient's response to treatment and the severity of the condition being treated.

Bayview Pharmacy is committed to providing high-quality compounded medications tailored to meet the unique needs of each patient. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide guidance on the use of Lidocaine 20%/Ketoprofen 20% Topical Ointment. If you have any questions or require further information, please do not hesitate to reach out to us.

Drug Interactions

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The Lidocaine 20%/Ketoprofen 20% Topical Ointment is a compounded medication designed for external application to the skin. Lidocaine is a local anesthetic that works by causing a temporary loss of sensation in the area where it is applied. It is used to relieve pain associated with various skin conditions. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation and pain in the tissues where it is applied. This combination is typically used for the localized treatment of conditions such as musculoskeletal pain, arthritis-related discomfort, or sports injuries.

When using this topical ointment, it is important to consider potential drug interactions. Lidocaine, when applied topically, is generally considered to have a low risk of systemic drug interactions due to minimal absorption. However, caution should be exercised when lidocaine is used in conjunction with other local anesthetics or medications that affect cardiac conduction, as there is a potential for additive systemic effects, particularly with excessive use or application to large areas of broken skin.

Ketoprofen, although used topically, may still contribute to systemic NSAID exposure. Caution is advised when this medication is used concurrently with other NSAIDs, including oral formulations, as this may increase the risk of adverse effects such as gastrointestinal irritation or bleeding, and renal impairment. Additionally, the use of ketoprofen with anticoagulants (such as warfarin) or antiplatelet agents (such as aspirin) may enhance the risk of bleeding. Patients should also be aware of the potential for increased photosensitivity; concurrent use with other photosensitizing agents may necessitate protective measures against ultraviolet exposure.

It is also important to consider the impact of the ointment base itself, as the greasy or oily formulation can affect the absorption of other concurrently used topical medications. Patients should be advised to allow adequate time between the application of different topical products to ensure proper absorption and to minimize interactions at the site of application.

Patients should be instructed to inform their healthcare providers of all medications they are currently taking, including over-the-counter drugs, supplements, and other topical treatments, to ensure safe use of Lidocaine 20%/Ketoprofen 20% Topical Ointment. Prescribers should review the patient's medication profile for potential interactions and adjust therapy as necessary.

If you have any questions or require further information regarding the use of this formulation or potential drug interactions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing you with the necessary support and guidance to ensure the safe and effective use of compounded medications.

How Does it Work

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The Lidocaine 20%/Ketoprofen 20% Topical Ointment is a specially compounded medication designed for external application to the skin. This semi-solid formulation is dispensed in a tube and provides a greasy or oily base, which not only facilitates the application of the medication but also enhances the penetration of the active ingredients into the skin. The ointment base serves as a vehicle to deliver the therapeutic agents directly to the site of pain or inflammation for localized treatment.

Lidocaine is a local anesthetic that works by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect to the area of application. When applied topically, lidocaine can help alleviate localized pain, making it useful for conditions that involve nerve-related pain or discomfort. By incorporating a high concentration of 20%, this formulation aims to provide significant analgesic effects for more severe or resistant cases of pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that exerts its effects by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins. Prostaglandins are chemical messengers that play a key role in the inflammation process. By reducing their production, ketoprofen effectively decreases inflammation and associated symptoms such as swelling, redness, and pain. The 20% concentration of ketoprofen in this ointment is intended to offer potent anti-inflammatory benefits, targeting localized inflammatory conditions directly at the source.

The combination of lidocaine and ketoprofen in this topical ointment provides both immediate pain relief and longer-term anti-inflammatory action. This dual mechanism makes the formulation particularly suitable for treating conditions such as tendonitis, bursitis, arthritis, or other musculoskeletal disorders where both pain and inflammation are present. Additionally, it may be used for the symptomatic relief of neuropathic pain or as an adjunct to other therapies in the management of more complex pain syndromes.

It is important for patients and prescribers to understand that this formulation should be used as directed, and the application area should be clean and intact skin. The ointment should not be applied to open wounds or mucous membranes. Patients should be advised to wash their hands before and after applying the ointment unless the hands are the treated area. As with any medication, there may be potential side effects, and it is essential to monitor for signs of systemic absorption, particularly with prolonged use or application over large areas of the body.

If you have any questions about the Lidocaine 20%/Ketoprofen 20% Topical Ointment or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this compounded medication.

Other Uses

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The combination of Lidocaine 20% and Ketoprofen 20% in a topical ointment provides a unique therapeutic approach primarily designed to manage localized pain and inflammation. Beyond the more commonly recognized uses such as the treatment of soft tissue injuries, minor wounds, and inflammatory dermatological conditions, there are several other ways in which this semi-solid formulation could potentially benefit patients.

For individuals suffering from localized musculoskeletal conditions like bursitis, tendonitis, and localized pockets of arthritis, this ointment may offer symptomatic relief. Lidocaine serves as a local anesthetic, temporarily numbing the area where the ointment is applied, which could help in reducing pain perception for such conditions. Ketoprofen, being a nonsteroidal anti-inflammatory drug (NSAID), helps in reducing inflammation which is a typical feature in these musculoskeletal conditions.

Additionally, the anesthetic component, Lidocaine, may prove beneficial for patients undergoing superficial dermatological procedures, such as laser hair removal or tattoo placement, by decreasing the discomfort associated with these procedures. It is worth noting that the formulation can also assist with the post-procedure recovery by managing inflammation through Ketoprofen.

Chronic conditions such as neuropathic pain or certain types of neuralgia, like post-herpetic neuralgia, could also see symptomatic improvement with the utilization of this formulation. While it does not cure the underlying cause of nerve pain, the Lidocaine can dull the pain sensation and provide temporary relief, and ongoing treatment with Ketoprofen may contribute to a decrease in surrounding inflammation that could otherwise exacerbate the neuropathic pain.

Sports-related applications such as pre- and post-exercise treatment for muscle soreness or strain may also benefit from this topical ointment. As exercise-induced muscle damage often leads to inflammation and pain, applying this formulation before or after exercise sessions may aid in decreasing these symptoms and enhance recovery.

This Lidocaine/Ketoprofen topical ointment might also be considered, off-label, for other types of localized pain syndromes such as plantar fasciitis or carpal tunnel syndrome, where the combination of anesthetic and anti-inflammatory effects may provide some symptomatic respite. Care must be taken with this off-label use, and it should only be pursued under the guidance of a healthcare professional.

It should be emphasized that while this Lidocaine/Ketoprofen ointment has potential use in various conditions, it is intended for localized treatment only and is not suitable for widespread application or for use on broken or significantly damaged skin. It is crucial to use this medication as directed by a healthcare provider to ensure safety and effectiveness.

Patients and prescribers must consider individual patient circumstances and the possibility of adverse effects or interactions with other medications. As with any medical treatment, it is always best to consult with a healthcare provider for personalized advice. If you have any questions regarding the formulation and its potential uses, please reach out to us at Bayview Pharmacy. Our knowledge as compounding pharmacists ensures that we can support your treatment plans with customized solutions and comprehensive care.

Frequently Asked Questions

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What is Lidocaine/Ketoprofen Topical Ointment used for?

This compounded formulation is primarily used for providing localized relief from pain and inflammation. The Lidocaine is an anesthetic that helps numb the area, while Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation. It may be prescribed for conditions such as joint pain, muscle aches, or certain skin conditions.

How should Lidocaine/Ketoprofen Topical Ointment be applied?

The ointment should be applied to clean, dry skin. Squeeze a small amount from the tube onto the affected area and gently rub in until fully absorbed. Be sure to wash your hands before and after application unless the treated area includes your hands.

How often can I use this topical ointment?

It is important to follow your healthcare provider's instructions regarding dosage and frequency of use, as this can vary depending on the individual's condition and response to treatment. Do not apply more often than prescribed.

Are there any side effects associated with Lidocaine/Ketoprofen Topical Ointment?

Like all medications, side effects are possible. Common side effects may include mild skin irritation at the site of application. More serious side effects can occur, such as allergic reactions, but are less common. If you experience any severe side effects or signs of allergy, seek medical attention immediately.

Can I cover the treated area with a bandage after applying the ointment?

Unless advised by your healthcare provider, it is generally not necessary to cover the treated area with a bandage. Applying an occlusive dressing may increase absorption and the risk of side effects. If you have been advised to cover the area, use a breathable bandage and follow your healthcare provider's instructions.

Is this ointment safe to use on all areas of the body?

The ointment is intended for external use only and should not be applied to certain sensitive areas of the body such as the eyes, inside the mouth or nose, or on genital areas. Avoid application to broken or damaged skin unless directed by your healthcare provider.

Can Lidocaine/Ketoprofen Topical Ointment be used in children?

The safety and efficacy of this compounded formulation in children have not been established. Use in pediatric populations should only be under the direction and supervision of a healthcare provider.

What should I do if I accidentally ingest the ointment?

If the ointment is accidentally ingested, seek medical attention immediately or call a Poison Control Center. Keep the ointment out of reach of children to prevent accidental ingestion.

How should I store the Lidocaine/Ketoprofen Topical Ointment?

Store the ointment at room temperature, away from heat and direct light. Do not freeze the medication, and keep the tube tightly closed when not in use. Keep the ointment out of reach of children and pets.

Can I use Lidocaine/Ketoprofen Topical Ointment if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. The potential risks and benefits should be carefully weighed, as some medications can be absorbed through the skin and may have effects on the unborn child or pass into breast milk.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.