Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream is a compounded medication specifically designed to provide localized anesthesia by numbing the skin and surrounding tissues. This formulation combines the anesthetic effects of three different agents: lidocaine, prilocaine, and tetracaine, each with its own onset and duration of action, to create a synergistic effect that enhances the overall numbing capability and duration of the cream. Lidocaine is a well-known amide local anesthetic that provides rapid onset of action, while prilocaine, also an amide, complements lidocaine with its similar anesthetic properties. Tetracaine, an ester local anesthetic, extends the duration of the anesthetic effect due to its longer half-life.

The cream is compounded into a semisolid preparation and is dispensed in a pump mechanism container. This delivery system is designed for ease of use, allowing for a controlled and hygienic application while minimizing the risk of contamination. The pump dispenses a consistent amount of cream with each use, ensuring accurate dosing and uniform application to the treatment area.

This topical anesthetic cream is indicated for use in various procedures that require skin anesthesia, such as minor surgical procedures, laser treatments, tattoo application and removal, and dermal procedures like injections or venipuncture. By numbing the skin, it helps to reduce the pain and discomfort associated with these procedures. The combination of active ingredients in this formulation works to provide a rapid onset of anesthesia with a prolonged duration, making it suitable for both short and long procedures.

Patients and prescribers should be aware that this compounded medication must be used as directed to ensure safety and efficacy. It is important to apply the cream only to intact skin and avoid application to open wounds or mucous membranes. The duration of application before the procedure can vary depending on the desired depth of anesthesia, and this should be discussed with a healthcare professional. Additionally, patients should be informed about the potential for local and systemic side effects, although these are rare when the cream is used as directed.

For prescribers, it is crucial to consider the patient's medical history, including any known allergies to local anesthetics, and to provide appropriate dosing instructions. As with all compounded medications, this cream is prepared to meet individual patient needs and should be prescribed with a clear understanding of the patient's specific requirements for their procedure.

If you have any questions regarding this formulation or its appropriate use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is committed to providing the highest quality of care and is available to assist with any inquiries you may have.

The Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream is a compounded medication that combines three local anesthetics for the purpose of providing localized pain relief and anesthesia. This formulation is particularly used for procedures that require numbing of the skin, such as minor surgical procedures, needle insertions, and superficial dermatological procedures. The active ingredients work by blocking nerve signals in the body, which helps to reduce pain sensation in the area where the cream is applied.

When using this topical cream, it is important to consider potential drug interactions. Lidocaine, prilocaine, and tetracaine are all metabolized by the liver, and therefore, drugs that affect liver enzymes, particularly cytochrome P450 isoenzymes, may alter the metabolism of these local anesthetics. For example, certain anti-arrhythmic drugs, such as amiodarone, can inhibit the metabolism of lidocaine, potentially leading to increased plasma concentrations and risk of systemic toxicity. Similarly, the concurrent use of other local anesthetics or medications with similar metabolic pathways may increase the risk of additive systemic effects, including CNS depression and cardiovascular effects.

Patients should also be cautious when using other topical medications in the same area where the Lidocaine/Prilocaine/Tetracaine cream is applied, as there may be an increased risk of systemic absorption of both medications. This is particularly relevant for other topical anesthetics or medications that can cause vasoconstriction or vasodilation, as these effects can alter the absorption of the local anesthetics.

It is also important to note that methemoglobinemia is a rare but serious condition associated with the use of prilocaine. Drugs that induce methemoglobinemia, such as sulfonamides, acetaminophen, benzocaine, and nitrates, should be used with caution in patients receiving this topical cream, as the risk may be increased.

Patients with a history of hypersensitivity to local anesthetics of the amide or ester type should avoid using this cream, as cross-sensitivity between members of these classes can occur. Additionally, caution should be exercised in patients taking monoamine oxidase inhibitors (MAOIs) or certain antidepressants, as these can potentiate the effects of local anesthetics.

Given the complexity of potential drug interactions, it is essential for patients and prescribers to provide a complete medication history, including over-the-counter drugs and herbal supplements, to the compounding pharmacist. This will allow for a thorough evaluation of any possible interactions and ensure the safe use of the Lidocaine/Prilocaine/Tetracaine Topical Cream. If you have any questions or require further information regarding this formulation and its use, please reach out to us at Bayview Pharmacy for assistance.

The Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream is a compounded medication that combines the effects of three different local anesthetics to provide effective skin numbing for various medical procedures or conditions that require localized pain relief. This cream is formulated to be a semisolid preparation, which allows for a smooth and consistent application to the skin. The inclusion of a pump mechanism in the packaging is designed to offer patients and healthcare providers a convenient and controlled method of dispensing the medication, ensuring accurate dosing and minimizing waste.

Lidocaine, prilocaine, and tetracaine are all amide-type local anesthetics that work by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect on the skin. Lidocaine is known for its rapid onset of action and intermediate duration of effect. Prilocaine, similar to lidocaine, has a quick onset and is often used in combination with other anesthetics to enhance the overall numbing effect. Tetracaine, on the other hand, has a longer onset time but provides a more prolonged duration of anesthesia compared to lidocaine and prilocaine.

When applied topically, the combination of these three anesthetics in the cream formulation works synergistically to provide a more potent and longer-lasting numbing effect. This makes the cream particularly useful for procedures such as minor skin surgeries, needle insertions, laser treatments, and the management of chronic painful conditions like neuropathies. The cream is applied to the skin prior to the procedure, allowing enough time for the anesthetics to penetrate and numb the area effectively.

It is important for patients and prescribers to understand that while this cream is effective in numbing the skin, it should be used with caution. The dosage and application area should be limited to avoid systemic absorption, which could lead to toxicity. Additionally, the cream should not be applied to broken or inflamed skin, as this could increase systemic absorption. Patients with a history of sensitivity or allergic reactions to local anesthetics should not use this product.

For any questions or concerns regarding the use of Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream, or to discuss the suitability of this formulation for specific procedures or conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this compounded medication.

The Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream is an anesthetic cream typically used to numb the skin prior to certain medical procedures such as needle insertions, minor skin surgeries, and laser treatments. However, its application extends beyond these primary uses due to the properties of the individual components within the formulation.

One of the alternative uses includes providing temporary relief for pain associated with minor burns, including sunburns, where the primary ingredients help alleviate the acute discomfort by numbing the affected area. This compound cream could also be employed in the treatment of localized painful conditions such as insect bites, minor cuts, or scrapes, by reducing the sensation of pain upon application. Additionally, the formulation may be utilized in the management of chronic pain conditions like neuropathy or post-herpetic neuralgia under the advisement of a healthcare professional, to lessen ongoing pain sensations in the localized area of skin where it is applied.

Furthermore, some dermatologic conditions accompanied by itchiness or discomfort, such as dermatitis or certain forms of eczema, might benefit from the numbing effect of this compound, providing temporary relief of itching or pain. It is worth noting that while the cream has the potential for these uses, it should not be considered a primary treatment for underlying skin conditions and should only be used for symptomatic relief as directed by a healthcare provider.

When considering the use of this compounded cream outside of the originally intended applications, it is essential to consult with a healthcare professional to ensure appropriateness and safety. Factors such as the patient's medical history, potential drug interactions, and specific condition being treated will influence the decision to use this cream. The cream should be applied as directed and its use should be limited to the area of skin for which it is prescribed to avoid systemic absorption which might lead to adverse effects. Use on extensive areas of skin, broken skin, or mucous membranes is generally not advised unless under the supervision of a physician.

We encourage patients to reach out to us with any questions regarding alternative uses of the Lidocaine 2%/Prilocaine 1.5%/Tetracaine 4% Topical Cream. We are available to discuss the formulation's potential benefits and risks, and can provide guidance and support to ensure safe and effective use. Healthcare providers seeking to prescribe this compound for other uses are also welcome to contact our team of compounding pharmacists for more information or to discuss their patient's specific needs.