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Formulas

Levetiracetam 300 mg/ml Oral Liquid

Levetiracetam 300 mg/ml Oral Liquid is a specially compounded medication designed for oral use, offering a precise and manageable method for administering the active drug. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing tablets or capsules, such as those in pediatric and geriatric groups. The medication is indicated for the treatment of epilepsy and seizure disorders, providing a critical therapeutic option for managing and controlling seizures in affected individuals. The high concentration of 300 mg/ml allows for the administration of the required dose in a smaller volume of liquid, facilitating ease of use and enhancing patient compliance.

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Levetiracetam
Oral Liquid
65b08338a38ce3c9ced09e90
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Formula Information

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Levetiracetam 300 mg/ml Oral Liquid is a custom-compounded medication designed for ease of administration and precise dosing. This oral liquid formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as children and the elderly. The high concentration of 300 mg/ml allows for administration of the required dose in a smaller volume of liquid, which can be easier for patients to ingest.

Levetiracetam is an antiepileptic drug (AED) that is used to treat various types of seizures in patients with epilepsy. It works by modulating neurotransmitter release and acting on synaptic vesicle proteins, which helps to stabilize neuronal activity and prevent seizure episodes. This medication is often chosen for its relatively favorable side effect profile and its lack of significant drug interactions, making it a suitable option for many patients, including those with multiple medications.

The oral liquid form of Levetiracetam ensures that patients who are unable to take solid forms of medication can still receive their necessary treatment. It is also useful for titrating doses to the specific needs of the patient, which is particularly important in the management of epilepsy where individual response to medication can vary widely. The liquid formulation can be easily measured with a syringe or dropper for accurate dosing, and it can be mixed with a small amount of food or drink to improve palatability if needed.

For prescribers, it is important to note that this compounded formulation of Levetiracetam should be used in accordance with the same indications, dosing guidelines, and monitoring requirements as the commercially available products. As with all antiepileptic drugs, the dose of Levetiracetam should be individualized according to the patient's response and tolerability. Monitoring of renal function is recommended, as Levetiracetam is primarily excreted by the kidneys, and dose adjustments may be necessary in patients with renal impairment.

Patients and prescribers should be aware that this medication should be taken consistently, at the same time each day, to maintain steady blood levels and optimal seizure control. Abrupt discontinuation should be avoided as it may lead to an increase in seizure frequency. Any changes to the medication regimen should be made under the guidance of a healthcare professional.

Bayview Pharmacy is committed to providing high-quality, patient-specific compounding services. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide support to both patients and healthcare providers. If you have any questions about Levetiracetam 300 mg/ml Oral Liquid or any other compounding needs, please reach out to us for assistance.

Drug Interactions

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Levetiracetam is an antiepileptic drug used to treat seizures in various forms of epilepsy. When considering the use of levetiracetam 300 mg/ml oral liquid, it is important to be aware of potential drug interactions that may affect its efficacy or increase the risk of adverse effects. Levetiracetam has a unique mechanism of action and does not extensively bind to plasma proteins, which reduces the likelihood of interactions with other drugs that are highly protein-bound. However, interactions can still occur.

Concomitant use of levetiracetam with other central nervous system (CNS) depressants, such as opioids, benzodiazepines, and alcohol, may increase CNS depression. This can lead to increased drowsiness, dizziness, and difficulty concentrating. Patients should be advised to avoid or limit the use of alcohol while taking this medication and to be cautious when taking other CNS depressants.

Levetiracetam is primarily excreted by the kidneys, and drugs that affect renal function could alter the levels of levetiracetam in the body. Medications such as NSAIDs and certain antihypertensives can affect kidney function, and their use should be monitored closely in patients taking levetiracetam. Dose adjustments of levetiracetam may be necessary in patients with renal impairment or those taking medications that significantly impact renal function.

Although levetiracetam does not significantly induce or inhibit hepatic enzymes, it is still important to consider potential interactions with drugs that have a narrow therapeutic index and are metabolized by the liver. Adjustments in dosages of the other drugs may be required when administered concurrently with levetiracetam.

Probenecid, a drug used to treat gout, can increase the levels of levetiracetam by affecting its renal excretion. Patients taking both medications should be monitored for signs of levetiracetam toxicity, and dosage adjustments may be necessary.

It is also important to note that while levetiracetam does not typically interact with hormonal contraceptives or anticoagulants, patients should always inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements, to ensure safe and effective use of levetiracetam oral liquid.

Patients should be counseled to report any unusual side effects or concerns to their healthcare provider promptly. Prescribers should review the patient's medication profile for potential interactions before prescribing levetiracetam oral liquid and during follow-up visits. For any questions or additional information regarding drug interactions with levetiracetam 300 mg/ml oral liquid, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide support and guidance to ensure the safe and effective use of this medication.

How Does it Work

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Levetiracetam is an antiepileptic drug that is used to treat seizures in patients with epilepsy. The 300 mg/ml oral liquid formulation of levetiracetam is designed to provide a high concentration of the medication in a liquid form, making it easier for patients who have difficulty swallowing pills, such as children and the elderly, to take their medication. This liquid formulation allows for precise dosing, which is critical in the management of epilepsy where dose accuracy can significantly impact the control of seizures.

The mechanism by which levetiracetam exerts its antiepileptic effects is not fully understood. However, it is believed to work differently from other antiepileptic drugs. Levetiracetam is thought to modulate the activity of a synaptic vesicle protein, SV2A, which is involved in the release of neurotransmitters in the brain. By binding to SV2A, levetiracetam may inhibit presynaptic calcium channels, reducing the release of neurotransmitters and thereby stabilizing neuronal activity. This action helps to prevent the abnormal electrical activity in the brain that causes seizures.

Levetiracetam is used to treat various types of seizures, including partial-onset seizures, myoclonic seizures in patients with juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in individuals with idiopathic generalized epilepsy. It can be used alone or in combination with other antiepileptic medications. The oral liquid formulation is particularly useful for patients who require a flexible dosing regimen or those who are unable to use other forms of the medication due to swallowing difficulties or other issues.

It is important for patients and prescribers to work closely to determine the appropriate dose of levetiracetam, as it can vary based on individual needs and response to the medication. Regular monitoring and dose adjustments may be necessary to achieve optimal seizure control while minimizing potential side effects. Patients should be advised to take the medication consistently and not to discontinue use abruptly, as this may lead to an increase in seizure frequency or severity.

If you have any questions about the levetiracetam 300 mg/ml oral liquid formulation or its use in treating epilepsy, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your condition or that of your loved ones.

Other Uses

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Levetiracetam is an antiepileptic drug primarily used for the treatment of seizure disorders, including partial-onset seizures, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in patients with epilepsy. However, the flexibility of a 300 mg/ml oral liquid form extends its utility beyond these indications. For instance, it can be used off-label to manage seizures in neonatal patients or in other conditions where seizure-like activities are noted and a liquid dosage form is preferred for dosing accuracy or ease of administration. Additionally, levetiracetam has been studied for potential use in the treatment of certain mood disorders and psychiatric conditions where stabilization of neuronal excitability may be beneficial. It should be noted that off-label uses require careful consideration by the prescribing physician, taking into account the specific patient's medical history and current clinical status.

Furthermore, the 300 mg/ml concentration allows for customization of doses that might be necessary for individual patients whose optimal therapeutic dosages fall outside of the standard solid dosage forms available on the market. This can be particularly useful in pediatric and geriatric patients, as well as in patients with renal impairment where dose adjustments are often necessary. In such populations, a liquid formulation can greatly simplify the process of titrating doses to achieve the desired therapeutic effect while minimizing potential adverse reactions.

In addition to the more common uses of levetiracetam, some researchers have explored its application in the field of neuro-oncology. There is ongoing research to understand the potential neuroprotective effects of levetiracetam in patients undergoing brain surgery or those with brain tumors suffering from seizures. While this area of use is still under investigation, it sheds light on the possible broader application of this medication beyond conventional seizure disorders.

Although levetiracetam oral liquid presents several advantages in terms of ease of administration and dosing flexibility, it is critical to ensure that it is used under the supervision of a healthcare provider. Patients or prescribers with questions about the use of levetiracetam 300 mg/ml oral liquid, including potential off-label uses or dose adjustments, are encouraged to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is ready to provide the necessary guidance and support for optimal treatment outcomes.

Frequently Asked Questions

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What is Levetiracetam 300 mg/ml Oral Liquid used for?

Levetiracetam 300 mg/ml Oral Liquid is used to treat epilepsy and prevent seizures. It is often prescribed to individuals who may have difficulty swallowing solid dosage forms, such as tablets or capsules, including pediatric and geriatric patients.

How should I take Levetiracetam 300 mg/ml Oral Liquid?

This medication should be taken as directed by your healthcare provider. The liquid should be measured with an appropriate dosing syringe or cup and taken by mouth, with or without food. Be sure to follow your prescribed dosing schedule closely.

What are the benefits of using the oral liquid form of Levetiracetam?

The oral liquid form of Levetiracetam provides a convenient and easily ingested option for patients who have trouble with pills. It allows for accurate dosage and is suitable for individuals who require flexible dosing, such as children and elderly patients.

Can the Levetiracetam Oral Liquid be mixed with other liquids?

In some cases, it may be possible to mix the oral liquid with a small amount of food or drink to make it easier to take. However, you should always check with your healthcare provider or pharmacist before mixing it with anything to ensure that the effectiveness of the medication is not compromised.

Should I take Levetiracetam Oral Liquid with food?

Levetiracetam Oral Liquid can be taken with or without food. If you experience stomach upset, taking it with food may help alleviate these symptoms. Always follow the instructions provided by your healthcare professional.

What should I do if I miss a dose of Levetiracetam Oral Liquid?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take double doses to make up for the missed one.

Are there any potential side effects of Levetiracetam Oral Liquid?

As with any medication, there may be side effects. The most common ones include drowsiness, dizziness, and tiredness. If you experience any serious side effects, such as changes in mood or behavior or difficulty breathing, contact your healthcare provider immediately.

How should Levetiracetam Oral Liquid be stored?

Levetiracetam Oral Liquid should be stored at room temperature, away from light and moisture. Keep the bottle closed tightly. It is important to keep this medication out of reach of children and pets.

Can Levetiracetam Oral Liquid be used for children?

Yes, Levetiracetam Oral Liquid is often prescribed for children, as it allows for specific dosing and is easier to swallow than pills or capsules. The appropriate dose for a child should be determined by a pediatrician or healthcare provider based on their individual needs.

Is it safe to drive or operate machinery after taking Levetiracetam Oral Liquid?

Levetiracetam can cause dizziness or drowsiness, so you should know how this medication affects you before you drive or operate machinery. If you experience these side effects, you should avoid such activities until you feel safe to perform them.

What should I do if I take too much Levetiracetam Oral Liquid?

In the event of an overdose, seek medical attention immediately. Symptoms of an overdose may include extreme drowsiness, agitation, and aggression. It is essential to adhere to the prescribed dose to avoid any adverse effects.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.