The Ketoprofen 20%/Lidocaine 10% Transdermal Gel is a specialized medication compounded by Bayview Pharmacy to provide targeted relief from pain and inflammation. This semisolid formulation is designed to be dispensed through a pump mechanism, which ensures that patients can apply a precise dose of the medication directly to the affected area. The gel base allows for a smooth application and facilitates the transdermal delivery of the active ingredients, ketoprofen and lidocaine, through the skin and into the underlying tissues.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the body's production of substances that cause inflammation, pain, and fever. It is effective in treating various conditions such as arthritis, muscle pain, and soft tissue injuries by reducing inflammation and providing analgesic effects. Lidocaine, on the other hand, is a local anesthetic that provides immediate relief from pain by blocking the transmission of pain signals along the nerves. The combination of these two active ingredients in a 20%/10% concentration makes the gel particularly effective for patients experiencing both acute and chronic pain conditions.

The transdermal delivery system of this gel formulation offers several advantages over oral medications, including localized treatment, reduced systemic side effects, and the potential for improved patient compliance due to its ease of use. The gel is particularly suited for patients who may have difficulties with oral administration or those who require a rapid onset of pain relief in a specific area of the body.

It is important for both patients and prescribers to understand that while this compounded medication can be highly effective for managing pain and inflammation, it should be used under the guidance of a healthcare professional. The prescriber should consider the patient's medical history, current medications, and the potential for drug interactions before recommending this formulation. Patients should follow the application instructions provided by the pharmacy and report any adverse effects or concerns to their healthcare provider immediately.

Bayview Pharmacy is committed to providing high-quality, customized medications to meet the unique needs of each patient. If you have any questions about the Ketoprofen 20%/Lidocaine 10% Transdermal Gel or would like to discuss its suitability for your condition, please do not hesitate to reach out to us. Our team of expert compounding pharmacists is here to assist you with any inquiries or concerns you may have.

The Ketoprofen 20%/Lidocaine 10% Transdermal Gel is a topical medication designed for the relief of pain and inflammation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. Lidocaine is a local anesthetic that provides temporary numbness and relief of pain in the area where it is applied. This combination is particularly useful for conditions such as arthritis, muscle pain, and similar inflammatory disorders.

When using this transdermal gel, it is important to consider potential drug interactions. Ketoprofen, being an NSAID, can interact with other NSAIDs, including aspirin, increasing the risk of gastrointestinal bleeding or ulcers. It is advisable to avoid concurrent use with other NSAIDs unless directed by a healthcare provider. Additionally, ketoprofen may interact with anticoagulants such as warfarin, antiplatelet drugs like clopidogrel, selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs), enhancing the risk of bleeding. Patients should inform their healthcare provider if they are taking any of these medications.

Lidocaine, on the other hand, may interact with antiarrhythmic drugs such as tocainide and mexiletine, as well as other local anesthetics. Caution is advised when using this medication concurrently with drugs that may cause methemoglobinemia, a condition where the blood is unable to carry oxygen effectively. Such drugs include nitrates, nitrites, and certain antibiotics like dapsone and sulfonamides.

Patients with liver disease should use this medication with caution, as both ketoprofen and lidocaine are metabolized in the liver. Impaired liver function may lead to increased levels of the drugs in the body, potentially causing toxicity. It is also important to avoid applying the gel to broken or irritated skin, as this may increase systemic absorption and the risk of side effects.

It is essential to inform the healthcare provider of all medications, supplements, and herbal products the patient is currently taking to avoid potential interactions. This includes over-the-counter medications, as they may also interact with the active ingredients in this formulation. If there are any signs of adverse reactions or interactions, such as unusual bleeding, bruising, or signs of an allergic reaction, patients should seek medical attention immediately.

For any questions or concerns regarding the use of Ketoprofen 20%/Lidocaine 10% Transdermal Gel, or to report any adverse events or interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The Ketoprofen 20%/Lidocaine 10% Transdermal Gel is a specialized medication designed for topical application to provide localized relief from pain and inflammation. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose of the medication to the affected area. The gel base allows for the active ingredients to be delivered directly to the site of pain or inflammation, offering targeted treatment without the systemic side effects often associated with oral medications.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are chemical messengers that play a key role in the inflammation process. By reducing their production, ketoprofen effectively decreases inflammation and associated pain. This makes the gel particularly useful for treating conditions such as arthritis, muscle sprains, strains, and other musculoskeletal injuries where inflammation is a primary cause of pain.

Lidocaine, on the other hand, is a local anesthetic that provides symptomatic relief by blocking the sodium channels responsible for conducting pain signals in the nerves. When applied topically, lidocaine can numb the treated area, thereby providing immediate relief from pain. This can be especially beneficial for patients who experience sharp, shooting, or burning types of pain.

The combination of ketoprofen and lidocaine in a transdermal gel form offers the benefits of both pain relief and anti-inflammatory action. The gel formulation allows for the active ingredients to penetrate the skin and reach the underlying tissues where they exert their effects. This localized approach helps to minimize systemic absorption and reduces the risk of systemic side effects, which can be particularly important for patients who may not tolerate oral NSAIDs or for those who require long-term pain management.

It is important for both patients and prescribers to understand that while this transdermal gel provides targeted relief, it should be used with caution in patients with known hypersensitivity to NSAIDs or local anesthetics, and it should not be applied to broken or irritated skin. Additionally, the use of occlusive dressings over the application site should be avoided unless directed by a healthcare professional, as this may increase systemic absorption of the active ingredients.

For any questions regarding the use of Ketoprofen 20%/Lidocaine 10% Transdermal Gel, or to discuss whether this formulation is appropriate for a specific patient's treatment plan, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The semisolid formulation of Ketoprofen 20%/Lidocaine 10% Transdermal Gel, delivered through a pump mechanism, is primarily indicated for the management of pain and inflammation associated with conditions like arthritis, sprains, strains, and other musculoskeletal injuries. However, this compounded gel may also have utility in other clinical scenarios due to the pharmacological properties of its constituent medications. For instance, ketoprofen, as a nonsteroidal anti-inflammatory drug (NSAID), may provide symptomatic relief for individuals suffering from tendinitis or bursitis by reducing the inflammatory process in these conditions, and lidocaine, a local anesthetic, may alleviate the discomfort associated with neuralgia or postherpetic neuralgia by numbing the affected area.

Moreover, the transdermal delivery system offers the potential for off-label applications, such as localized symptom management in specific dermatological conditions that may be characterized by inflammatory pain, where the ingredients are suitable for use. The gel's properties allow for a directed approach to therapy, minimizing systemic exposure and associated side effects often seen with oral medications. This bespoke approach is particularly beneficial for patients who may have contraindications to systemic NSAIDs or require localized pain management without widespread anesthetic effects. As the gel is applied topically, it might also be considered for superficial joint and soft tissue discomfort where oral analgesics are less effective or desired.

Additionally, the ease of application via the pump mechanism allows patients to self-administer a measured dose of the medication, potentially improving adherence to treatment regimens. The gel consistency provides a soothing effect upon application, which can enhance patient comfort and experience. While the combination of ketoprofen and lidocaine in this formulation has a primary purpose, it holds the prospect of serving as an alternative option for patients seeking a non-invasive and targeted therapeutic approach for various localized pain conditions.

It is crucial to note that all uses beyond the primary indication should be based on the prescriber's discretion and on a thorough evaluation of the patient's specific clinical situation. This formulation's safety and efficacy for conditions beyond the originally intended uses have not been established, and therefore, must be prescribed and used with caution. Compounding pharmacists at Bayview Pharmacy are available to discuss this formulation's potential applications, offer guidance on appropriate use, and provide detailed information on the product. For any questions or if there is a need for additional information on this compound, please do not hesitate to reach out to us.