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Ibuprofen 20%/Piroxicam 1% Topical Gel

Bayview Pharmacy's Ibuprofen 20%/Piroxicam 1% Topical Gel is a semisolid formulation, dispensed through a pump mechanism for easy and precise application. This compounded medication is designed for targeted treatment of conditions such as Osteoarthritis, Rheumatoid Arthritis, Tendinitis, Bursitis, and Gout, delivering active ingredients directly to the affected area in a gel-like consistency.

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Topical Gel
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Formula Information

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Ibuprofen 20%/Piroxicam 1% Topical Gel is a specially compounded medication designed to address various inflammatory conditions. This unique formulation combines two potent non-steroidal anti-inflammatory drugs (NSAIDs), Ibuprofen and Piroxicam, to create a synergistic effect that effectively reduces inflammation and pain. Ibuprofen functions as a non-selective COX inhibitor, while Piroxicam operates as a selective COX-2 inhibitor. This dual-action approach has proven effective in treating a range of conditions, including arthritis, tendinitis, bursitis, and other musculoskeletal disorders.

The topical gel formulation is dispensed through a pump mechanism, which facilitates easy and precise application on the skin. This method of delivery allows for targeted treatment and absorption of the active ingredients, providing a sustained release that ensures a more consistent and prolonged effect compared to oral medications. The gel-like consistency of the Ibuprofen 20%/Piroxicam 1% Topical Gel also minimizes the risk of systemic side effects, such as gastrointestinal upset, which are often associated with oral medications.

As an effective treatment option, Ibuprofen 20%/Piroxicam 1% Topical Gel offers significant relief for patients suffering from inflammatory conditions. However, it is crucial to note that this formulation should not be used by patients with a known history of hypersensitivity to either Ibuprofen or Piroxicam. If you have any questions or concerns about this formulation, we encourage you to reach out for further information.

Drug Interactions

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Ibuprofen 20%/Piroxicam 1% Topical Gel is a semisolid formulation designed for easy and precise application on the skin. It is primarily used for the treatment of mild to moderate pain, inflammation, and swelling associated with various disease states. The active ingredients, Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), and Piroxicam, a cyclooxygenase-2 (COX-2) inhibitor, work together to alleviate these symptoms. However, this combination may increase the risk of gastrointestinal (GI) bleeding, ulceration, and perforation. Patients should promptly report any signs or symptoms of GI bleeding, such as epigastric pain, dyspepsia, melena, and hematemesis. It is also recommended to avoid alcohol while using this medication.

Concurrent use of Ibuprofen 20%/Piroxicam 1% Topical Gel with other NSAIDs or salicylates may heighten the risk of adverse reactions, including GI bleeding. Patients are advised against taking other NSAIDs or salicylates while using this medication. This topical gel may also increase the risk of serious cardiovascular (CV) events, such as myocardial infarction and stroke. Any signs or symptoms of a CV event, including chest pain, shortness of breath, or weakness on one side of the body, should be treated as a medical emergency.

Furthermore, Ibuprofen 20%/Piroxicam 1% Topical Gel may heighten the risk of serious skin reactions, including Stevens-Johnson Syndrome and toxic epidermal necrolysis. Any signs or symptoms of a serious skin reaction, such as rash, blisters, or peeling of the skin, should be treated as a medical emergency. This medication may also increase the risk of serious renal events, including acute renal failure. Any signs or symptoms of a serious renal event, such as decreased urine output, swelling of the extremities, or difficulty breathing, should be treated as a medical emergency.

If you have any questions about the use of Ibuprofen 20%/Piroxicam 1% Topical Gel, please do not hesitate to reach out for further information.

How Does it Work

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Ibuprofen 20%/Piroxicam 1% Topical Gel is a compounded formulation that combines two potent nonsteroidal anti-inflammatory drugs (NSAIDs), Ibuprofen and Piroxicam. These drugs are known for their efficacy in treating pain and inflammation. Ibuprofen functions as a non-selective COX inhibitor, while Piroxicam operates as a selective COX-2 inhibitor. The synergistic action of these two drugs effectively reduces inflammation and pain.

This topical gel is designed for direct application to the skin over the affected area. It is dispensed through a pump mechanism, which allows for easy and precise application. The active ingredients are absorbed through the skin and enter the bloodstream, where they work to alleviate inflammation and pain. Typically, the gel is applied two to three times a day, or as directed by a healthcare provider.

Ibuprofen 20%/Piroxicam 1% Topical Gel is used to manage a variety of conditions. These include arthritis, bursitis, tendinitis, and other musculoskeletal conditions. It is also effective in treating acute pain, such as that associated with a sprained ankle or other minor injuries.

While generally well tolerated, some individuals may experience skin irritation or other side effects from using Ibuprofen 20%/Piroxicam 1% Topical Gel. If you experience any adverse effects, it is recommended to discontinue use and contact your healthcare provider.

If you have any questions about Ibuprofen 20%/Piroxicam 1% Topical Gel or its mechanism of action, please do not hesitate to reach out. We are here to assist you in finding the most suitable treatment for your condition.

Other Uses

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Ibuprofen 20%/Piroxicam 1% Topical Gel is a compounded formulation that has been effectively used in the management of various musculoskeletal conditions. These include osteoarthritis, rheumatoid arthritis, tendinitis, bursitis, and gout. It has also shown efficacy in treating other conditions such as ankylosing spondylitis, psoriatic arthritis, and juvenile idiopathic arthritis.

Additionally, this topical gel has been utilized in the treatment of acute pain, including post-operative pain, and in reducing inflammation and swelling. It has also been beneficial in managing muscle and joint pain associated with fibromyalgia.

This formulation is designed for topical application on the skin, targeting the affected area directly. It is generally well tolerated, providing relief without the systemic side effects often associated with oral medications. However, it is crucial to avoid applying this formulation on open wounds or on areas of skin that are broken or irritated. Also, care should be taken to prevent contact with the eyes, nose, and mouth.

If you have any questions or concerns about the use of Ibuprofen 20%/Piroxicam 1% Topical Gel for any condition, please do not hesitate to reach out for further information. It is always important to use this medication as directed by a healthcare professional.

Frequently Asked Questions

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What is Ibuprofen 20%/Piroxicam 1% Topical Gel?

This is a compounded formulation of two active ingredients, Ibuprofen and Piroxicam, in a gel form. It is designed for topical application on the skin.

How is this formulation dispensed?

This formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin.

What is the consistency of this gel?

The gel has a semisolid consistency, which facilitates targeted treatment or absorption of the active ingredients.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Ibuprofen, which is present at a concentration of 20%, and Piroxicam, which is present at a concentration of 1%.

How should I apply this gel?

You should apply this gel directly to the affected area of the skin. The pump mechanism allows for easy and precise application.

What is the purpose of the Ibuprofen in this formulation?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation and pain.

What is the purpose of the Piroxicam in this formulation?

Piroxicam is also a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation and pain. It is used in this formulation to enhance the effects of Ibuprofen.

Can I use this gel for any type of pain?

This gel is designed for topical application to treat localized pain and inflammation. It may not be effective for all types of pain. Always consult your healthcare provider before using this medication.

Are there any side effects associated with this formulation?

As with any medication, there may be potential side effects. These can include skin irritation or allergic reactions. If you experience any unusual symptoms after applying the gel, stop using it and consult your healthcare provider immediately.

How should I store this gel?

Store this gel at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.