This oral suspension combines Hyoscyamine Sulfate at a concentration of 0.02 mg/mL and Lidocaine at 7 µg/mL in a liquid dosage form. The suspension ensures a uniform dispersion of the active ingredients throughout the liquid medium, providing a homogeneous mixture for precise dosing and administration.

Hyoscyamine Sulfate is an anticholinergic agent that works by inhibiting the action of acetylcholine on smooth muscles, thereby reducing spasms in the gastrointestinal tract. It is commonly used to manage symptoms associated with gastrointestinal disorders such as irritable bowel syndrome, peptic ulcers, and other conditions involving excessive motility and secretion. By decreasing muscle spasms, it helps alleviate pain, discomfort, and cramps.

Lidocaine is a local anesthetic that functions by blocking sodium channels, which inhibits nerve impulse conduction. When administered orally in small doses, it can help numb the lining of the gastrointestinal tract, providing relief from pain and discomfort. This can be particularly beneficial in conditions where inflammation or irritation leads to significant discomfort.

The combination of Hyoscyamine Sulfate and Lidocaine in this oral suspension provides both antispasmodic and analgesic effects. This synergistic approach offers comprehensive symptom relief for patients experiencing gastrointestinal spasms accompanied by pain. It may be particularly useful for individuals who have not responded adequately to standard treatments or require a customized therapeutic regimen.

For prescribers, this compounded formulation allows for tailored dosing to meet individual patient needs, especially when standard dosages are not suitable. The liquid form is advantageous for patients who have difficulty swallowing tablets or capsules, ensuring better compliance and ease of administration. Precise dosing adjustments can be made based on the patient's response and tolerability.

Patients are advised to use this medication exactly as prescribed by their healthcare provider. It is important to measure each dose carefully using a proper measuring device to ensure accuracy. Before each use, the suspension should be shaken well to guarantee even distribution of the active ingredients. Consistent dosing at the same times each day can help maintain optimal therapeutic levels.

Common side effects of Hyoscyamine Sulfate may include dry mouth, blurred vision, constipation, urinary retention, and increased heart rate due to its anticholinergic properties. Lidocaine may cause numbness in the mouth or throat, dizziness, or, in rare cases, allergic reactions. Patients should be monitored for any adverse reactions, and any unusual or severe symptoms should be reported to their healthcare provider promptly.

Caution is advised in patients with glaucoma, obstructive uropathy, obstructive gastrointestinal diseases, severe ulcerative colitis, myasthenia gravis, or in those who are sensitive to anticholinergic agents or local anesthetics. It is crucial for prescribers to assess the risks and benefits before initiating therapy in patients with these conditions. Regular follow-up appointments may be necessary to monitor the patient's response and adjust the treatment as needed.

The oral suspension should be stored at room temperature, away from direct light and moisture. It should be kept out of reach of children and pets. Do not use the medication past the expiration date indicated on the label. Proper storage helps maintain the efficacy and safety of the formulation.

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When considering the use of Hyoscyamine Sulfate 0.02mg/mL/Lidocaine 7 µg/mL Oral Suspension, it is crucial to be aware of potential drug interactions that may affect the efficacy and safety of this formulation. Hyoscyamine sulfate, an anticholinergic agent, and lidocaine, a local anesthetic, can interact with various medications, potentially leading to altered therapeutic effects or increased risk of adverse reactions.

Hyoscyamine sulfate may interact with other anticholinergic drugs, such as atropine, scopolamine, and certain antihistamines, leading to an additive anticholinergic effect. This can result in increased side effects such as dry mouth, blurred vision, constipation, and urinary retention. Patients should be monitored for these symptoms, and dose adjustments may be necessary.

Concomitant use of hyoscyamine sulfate with medications that have anticholinergic properties, such as tricyclic antidepressants (e.g., amitriptyline, nortriptyline) and certain antipsychotics (e.g., clozapine, olanzapine), can also enhance anticholinergic side effects. Caution is advised, and healthcare providers should assess the risk-benefit ratio when prescribing these combinations.

Lidocaine, as a local anesthetic, can interact with antiarrhythmic drugs, such as amiodarone and mexiletine, potentially leading to additive cardiac effects. This may increase the risk of arrhythmias or other cardiac complications. Patients with pre-existing cardiac conditions should be closely monitored, and alternative therapies should be considered if necessary.

Additionally, lidocaine may interact with beta-blockers (e.g., propranolol, metoprolol) and cimetidine, which can increase lidocaine plasma levels by reducing its hepatic clearance. This interaction may enhance the risk of lidocaine toxicity, characterized by symptoms such as dizziness, confusion, and seizures. Dose adjustments and monitoring of lidocaine levels may be required in these cases.

Patients taking medications that affect the cytochrome P450 enzyme system, particularly CYP3A4 inhibitors (e.g., ketoconazole, erythromycin), should be aware that these can increase the plasma concentration of lidocaine, potentially leading to toxicity. Conversely, CYP3A4 inducers (e.g., rifampin, phenytoin) may decrease lidocaine levels, reducing its efficacy. Regular monitoring and possible dose adjustments are recommended.

It is important for both patients and prescribers to be aware of these potential interactions and to communicate openly about all medications being taken, including over-the-counter drugs and supplements. If you have any questions or concerns regarding drug interactions with this formulation, please reach out to us for further guidance and support.

The Hyoscyamine Sulfate 0.02mg/mL/Lidocaine 7 µg/mL Oral Suspension is a compounded liquid formulation designed to provide therapeutic relief for specific gastrointestinal and urological conditions. This formulation combines the anticholinergic properties of hyoscyamine sulfate with the local anesthetic effects of lidocaine, offering a dual-action approach to symptom management.

Hyoscyamine sulfate is an anticholinergic agent that works by inhibiting the action of acetylcholine on smooth muscles and secretory glands. This action results in the relaxation of smooth muscle tissues in the gastrointestinal tract, reducing spasms and alleviating symptoms such as abdominal pain, cramping, and discomfort associated with conditions like irritable bowel syndrome (IBS) and other spastic digestive disorders. By decreasing the production of stomach acid and slowing intestinal motility, hyoscyamine sulfate helps manage symptoms of peptic ulcers and other hypersecretory conditions.

Lidocaine, on the other hand, is a local anesthetic that provides temporary relief from pain and discomfort by blocking nerve signals in the body. In this oral suspension, lidocaine acts locally within the gastrointestinal tract to numb the mucosal lining, offering immediate relief from pain and irritation. This can be particularly beneficial for patients experiencing acute episodes of pain or discomfort, as it allows for rapid symptom control while the hyoscyamine sulfate works to address the underlying muscle spasms and hyperactivity.

The liquid dosage form of this formulation ensures that the active ingredients are evenly dispersed throughout the suspension, providing a consistent and homogeneous mixture for administration. This is particularly advantageous for patients who may have difficulty swallowing tablets or capsules, as it allows for easy dose adjustments and precise administration. The liquid form also facilitates faster absorption of the active ingredients, leading to quicker onset of action compared to solid dosage forms.

For prescribers, this compounded formulation offers a customizable treatment option that can be tailored to the specific needs of each patient. The combination of hyoscyamine sulfate and lidocaine in a single suspension allows for a synergistic effect, enhancing the overall therapeutic outcome. It is important to consider the individual patient's medical history, current medications, and specific symptoms when prescribing this formulation to ensure optimal efficacy and safety.

Patients using this oral suspension should follow the prescribed dosage and administration instructions carefully to achieve the best results. It is essential to shake the bottle well before each use to ensure uniform distribution of the active ingredients. Patients should also be aware of potential side effects, such as dry mouth, blurred vision, dizziness, or drowsiness, which are commonly associated with anticholinergic agents like hyoscyamine sulfate. If any adverse reactions occur, patients should contact their healthcare provider promptly.

If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

The Hyoscyamine Sulfate 0.02mg/mL/Lidocaine 7 µg/mL Oral Suspension is a compounded liquid formulation designed to provide a uniform dispersion of active ingredients for ease of administration. While this formulation is primarily used for specific medical conditions, it may also have other potential applications that could be beneficial for both patients and prescribers to consider. Hyoscyamine sulfate, an anticholinergic agent, is known for its ability to reduce muscle spasms in the gastrointestinal tract, bladder, and other organs. This property can be leveraged in managing symptoms associated with irritable bowel syndrome (IBS), spastic colon, and other functional bowel disorders. Additionally, its antispasmodic effects may be useful in alleviating symptoms of bladder spasms and certain types of urinary incontinence.

Lidocaine, a local anesthetic, is included in this formulation to provide topical pain relief. Its presence in the oral suspension can be particularly advantageous for patients experiencing oral mucositis, a common side effect of chemotherapy and radiation therapy, which causes painful inflammation and ulceration of the mucous membranes in the mouth. By numbing the affected area, lidocaine can help improve the quality of life for these patients by reducing pain and discomfort during eating and speaking. Furthermore, the combination of hyoscyamine and lidocaine may offer synergistic benefits in managing pain and discomfort associated with gastrointestinal disorders, where both muscle spasms and localized pain are present.

For prescribers, this formulation offers a customizable approach to patient care, allowing for adjustments in dosage and concentration to meet individual patient needs. It is particularly useful for patients who have difficulty swallowing pills or require precise dosing adjustments that are not available in commercially manufactured products. The liquid form ensures that the active ingredients are evenly distributed, providing consistent therapeutic effects with each dose. As with any compounded medication, it is important for prescribers to consider the specific needs and medical history of their patients when determining the appropriateness of this formulation.

Patients should be aware that while this compounded oral suspension can offer relief for various conditions, it is essential to use it under the guidance of a healthcare professional. Potential side effects, drug interactions, and contraindications should be thoroughly discussed with a prescriber or pharmacist. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.