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Formulas

Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream

Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is used to treat inflammatory skin conditions and bacterial skin infections, providing localized treatment and absorption of active ingredients.

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Hydrocortisone Acetate
Nitrofurazone
Topical Cream
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Formula Information

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The Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream is a compounded semisolid preparation designed for convenient and controlled application on the skin. Dispensed in a pump mechanism, it allows for precise dosing and minimizes contamination, ensuring effective delivery of the active ingredients to the affected area.

Hydrocortisone Acetate is a corticosteroid that helps reduce inflammation, itching, and redness associated with various skin conditions. At a concentration of 1%, it provides anti-inflammatory effects that can alleviate symptoms and improve patient comfort.

Nitrofurazone, present at 0.2% concentration, is a topical antimicrobial agent effective against a broad spectrum of bacteria. It assists in preventing or treating bacterial infections on the skin, making this formulation beneficial for conditions that may be complicated by or prone to infection.

This combination cream is intended for use in managing skin conditions where both anti-inflammatory and antimicrobial actions are desired. By addressing inflammation and preventing bacterial growth, it supports the healing process and reduces the risk of complications associated with skin disorders.

Patients should apply the cream as directed by their healthcare provider, typically by dispensing a measured amount using the pump mechanism and gently applying a thin layer to the affected area. It is important to wash hands before and after application, unless the hands are the area being treated. The pump dispenser enhances ease of use and dosing accuracy, promoting adherence to the treatment regimen.

Prescribers may consider this compounded formulation for patients requiring targeted anti-inflammatory and antimicrobial therapy. The combined action of Hydrocortisone Acetate and Nitrofurazone can be advantageous in treating dermatological conditions that involve both inflammation and risk of infection.

Potential side effects include local irritation, dryness, or allergic reactions. Patients should be advised to report any adverse effects or unusual symptoms to their healthcare provider promptly. Prolonged use of topical corticosteroids may lead to skin thinning or systemic absorption, so it should be used according to prescribed directions.

If you have any questions regarding this formulation or its appropriate use, please reach out to us for further information.

Drug Interactions

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Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream is a compounded formulation designed for the treatment of inflammatory skin conditions and bacterial infections. Hydrocortisone acetate is a corticosteroid that helps reduce inflammation, redness, and itching by suppressing the immune response in the affected area. Nitrofurazone is an antibacterial agent that works by inhibiting bacterial enzymes, thereby preventing the growth and spread of bacteria. This combination is particularly useful in treating conditions where both inflammation and bacterial infection are present, such as infected eczema, dermatitis, or minor skin injuries.

When using this topical cream, it is important to consider potential drug interactions, especially for patients who are on multiple medications. Although the systemic absorption of topical hydrocortisone acetate is generally low, it can still interact with other medications that affect the immune system. For instance, concurrent use with other corticosteroids or immunosuppressive drugs may increase the risk of systemic side effects, such as adrenal suppression or increased susceptibility to infections. Patients should inform their healthcare provider about all the medications they are currently taking, including over-the-counter drugs and supplements, to avoid potential interactions.

Nitrofurazone, being a topical antibacterial agent, has minimal systemic absorption, which reduces the likelihood of systemic drug interactions. However, it is important to note that nitrofurazone may interact with other topical agents applied to the same area. For example, using other topical antibiotics or antiseptics concurrently may alter the effectiveness of nitrofurazone or increase the risk of skin irritation. Patients should be advised to avoid using other topical products on the treated area unless directed by their healthcare provider.

Patients with a known hypersensitivity to hydrocortisone, nitrofurazone, or any other component of the cream should avoid using this formulation. Additionally, caution is advised in patients with a history of allergic reactions to other corticosteroids or nitrofuran derivatives. If signs of an allergic reaction, such as rash, itching, or swelling, occur, the use of the cream should be discontinued immediately, and medical advice should be sought.

For prescribers, it is crucial to assess the patient's overall medication regimen and medical history to identify any potential interactions or contraindications. Monitoring for signs of systemic absorption, especially in long-term use or application over large surface areas, is recommended. Educating patients on the proper use of the pump mechanism for controlled application can enhance treatment efficacy and minimize the risk of adverse effects.

If you have any questions or need further information regarding this formulation, please reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is here to assist you with any inquiries or concerns you may have.

How Does it Work

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The Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream is a compounded formulation designed to deliver targeted therapeutic effects through a semisolid preparation. This formulation is dispensed in a pump mechanism, which ensures a convenient and controlled application, allowing for precise dosing and minimizing waste. The cream is intended for topical use, facilitating localized treatment and absorption of the active ingredients directly into the affected area of the skin.

Hydrocortisone Acetate, a corticosteroid, is included in this formulation at a concentration of 1%. It works by reducing inflammation, itching, and redness associated with various dermatological conditions. By inhibiting the release of inflammatory mediators, Hydrocortisone Acetate helps to alleviate symptoms of skin irritation and inflammation, providing relief to patients suffering from conditions such as eczema, dermatitis, and allergic reactions. Its anti-inflammatory properties make it an effective component in managing localized skin conditions, promoting healing and comfort.

Nitrofurazone, present at a concentration of 0.2%, is an antimicrobial agent that plays a crucial role in preventing and treating infections in the skin. It works by interfering with bacterial enzymes, thereby inhibiting bacterial growth and proliferation. Nitrofurazone is particularly effective against a broad spectrum of bacteria, making it a valuable addition to this formulation for treating or preventing infections in compromised skin areas. Its inclusion in the cream helps to protect the skin from bacterial contamination, especially in cases where the skin barrier is disrupted due to injury or inflammation.

The combination of Hydrocortisone Acetate and Nitrofurazone in this topical cream provides a dual-action approach to managing skin conditions. While Hydrocortisone Acetate addresses the inflammatory and symptomatic aspects, Nitrofurazone ensures that the risk of bacterial infection is minimized. This synergistic effect enhances the overall therapeutic outcome, making the formulation suitable for a variety of dermatological conditions where both inflammation and infection are concerns.

For patients and prescribers, the pump mechanism of this formulation offers a user-friendly application method, ensuring that the cream is dispensed in a consistent and hygienic manner. This design not only enhances patient compliance but also ensures that the active ingredients are delivered effectively to the site of application. The semisolid nature of the cream allows for easy spreading and absorption, ensuring that the therapeutic effects are localized to the area of concern.

If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries you may have regarding the use and benefits of Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream.

Other Uses

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The Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream, dispensed in a semisolid preparation with a pump mechanism, is primarily used for its anti-inflammatory and antibacterial properties. While it is commonly prescribed for specific dermatological conditions, such as eczema, psoriasis, and bacterial skin infections, there are several other potential uses for this formulation that may benefit patients and prescribers seeking alternative therapeutic options. This cream can be considered for off-label use in managing minor skin irritations and rashes that are not necessarily linked to chronic conditions but may benefit from the dual action of reducing inflammation and preventing bacterial growth. For instance, it may be used to alleviate symptoms of contact dermatitis caused by exposure to irritants or allergens, providing relief from itching and redness while minimizing the risk of secondary infections.

Additionally, the formulation may be beneficial in the post-operative care of minor surgical wounds or abrasions, where the risk of infection is a concern, and inflammation needs to be controlled to promote healing. The controlled application via the pump mechanism ensures precise dosing, reducing the risk of over-application and potential side effects. This feature is particularly advantageous for patients who require consistent and accurate dosing, such as those with sensitive skin or those managing chronic conditions that necessitate long-term topical treatment. Furthermore, the cream may be used in the management of insect bites or stings, where its anti-inflammatory properties can help reduce swelling and discomfort, while the antibacterial component helps prevent infection at the site of the bite.

For prescribers, considering the use of this formulation in patients with compromised skin barriers, such as those undergoing radiation therapy or with diabetic ulcers, may offer additional benefits. The combination of hydrocortisone acetate and nitrofurazone can aid in reducing inflammation and preventing infection in these vulnerable areas, potentially improving patient outcomes. However, it is crucial to evaluate each patient's specific condition and medical history to ensure the appropriateness of this treatment. As with any medication, it is essential to monitor for potential side effects, such as skin thinning or allergic reactions, and adjust treatment as necessary. If you have any questions or require further information about the potential uses of this formulation, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream used for?

This topical cream is used for the treatment of skin conditions that require anti-inflammatory and antibacterial action. Hydrocortisone acetate helps reduce inflammation, while nitrofurazone provides antibacterial properties to prevent or treat infections.

How should I apply the Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream?

Apply a small amount of the cream to the affected area using the pump mechanism for controlled dispensing. Gently rub it into the skin until it is evenly distributed. Follow your healthcare provider's instructions regarding the frequency and duration of use.

Can I use this cream on open wounds?

Consult your healthcare provider before applying this cream to open wounds. While nitrofurazone has antibacterial properties, the suitability of this cream for open wounds should be determined by a medical professional.

Are there any side effects associated with this topical cream?

Possible side effects may include skin irritation, redness, or itching at the application site. If you experience severe reactions or symptoms persist, discontinue use and consult your healthcare provider.

Is this cream suitable for children?

Consult a healthcare provider before using this cream on children. The safety and efficacy of this formulation for pediatric use should be evaluated by a medical professional.

How should I store the Hydrocortisone Acetate 1%/Nitrofurazone 0.2% Topical Cream?

Store the cream at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets to prevent accidental ingestion or misuse.

Can I use this cream if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult your healthcare provider before using this cream. They can provide guidance based on your specific circumstances and health needs.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra cream to make up for a missed dose.

Can I use other skincare products while using this topical cream?

Consult your healthcare provider before using other skincare products in conjunction with this cream. Some products may interact with the active ingredients, affecting their efficacy or causing irritation.

What should I do if I experience an allergic reaction to this cream?

If you experience signs of an allergic reaction, such as rash, swelling, or difficulty breathing, discontinue use immediately and seek medical attention. Inform your healthcare provider about the reaction for further guidance.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.