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Formulas

Hydrocortisone 2%/Clotrimazole 2% Topical Cream

The Hydrocortisone 2%/Clotrimazole 2% Topical Cream is a dual-action medication formulated to provide relief from various dermatological conditions. This semisolid preparation is dispensed in a pump mechanism, ensuring a convenient, controlled, and hygienic application. The cream is designed to be applied directly to the affected skin areas, facilitating localized treatment.

Hydrocortisone, a corticosteroid, helps to reduce inflammation, itching, and redness associated with skin irritations. Clotrimazole, an antifungal agent, effectively treats fungal skin infections. Together, these active ingredients make the cream suitable for the treatment of inflammatory skin disorders complicated by fungal infections, such as athlete's foot, jock itch, and ringworm. It may also be used to address eczema or dermatitis with a secondary fungal infection.

Patients are advised to use this cream as directed by a healthcare professional to ensure optimal results and to minimize the risk of side effects.

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Topical Cream
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Formula Information

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The Hydrocortisone 2%/Clotrimazole 2% Topical Cream is a specially compounded medication that combines the anti-inflammatory properties of hydrocortisone with the antifungal capabilities of clotrimazole. This dual-action cream is formulated to address a range of dermatological conditions that may involve inflammation and fungal infections. Hydrocortisone, a corticosteroid, works by reducing swelling, itching, and redness associated with skin irritations and allergic reactions. Clotrimazole, on the other hand, is an azole antifungal that inhibits the growth of various types of fungi by disrupting the production of the fungal cell membrane.

This cream is particularly effective in treating conditions such as athlete's foot, jock itch, ringworm, and certain types of dermatitis where a secondary fungal infection may be present or anticipated. The inclusion of hydrocortisone helps to alleviate inflammatory symptoms that often accompany these infections, providing relief from discomfort and promoting healing. The cream is compounded in a semisolid form and dispensed in a pump mechanism, which allows for a clean, convenient, and controlled application. This delivery system helps to ensure that the correct dose is administered each time, minimizing waste and reducing the risk of cross-contamination that can occur with traditional jar packaging.

For patients, it is important to apply the cream as directed by a healthcare provider, usually to the affected area twice daily or as prescribed. The area should be clean and dry before application. Patients should be advised to use the medication for the full prescribed length of time, even if symptoms improve before the course is complete, to prevent the recurrence of infection. Side effects may include skin irritation or a burning sensation at the application site. If these persist or worsen, patients should contact their healthcare provider.

Prescribers should consider this formulation for patients who require a combination therapy to address both inflammation and fungal infection in localized areas. It is essential to review the patient's medical history, including any known allergies to corticosteroids or azole antifungals, before prescribing this medication. Additionally, prescribers should monitor for potential systemic absorption of hydrocortisone, especially with prolonged use or application over large surface areas, which may lead to systemic corticosteroid effects.

At Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the specific needs of our patients. Our team of compounding pharmacists is available to answer any questions and provide guidance on the use of this Hydrocortisone 2%/Clotrimazole 2% Topical Cream. If you have any questions or require further information, please do not hesitate to reach out to us.

Drug Interactions

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The Hydrocortisone 2%/Clotrimazole 2% Topical Cream is a combination medication used for the treatment of various skin conditions. Hydrocortisone is a corticosteroid that reduces inflammation, redness, and swelling. Clotrimazole is an antifungal agent that treats fungal infections by inhibiting the growth of fungi. When used together in a topical cream, this formulation is effective in treating inflammatory skin conditions that are complicated by or at risk of fungal infections, such as certain types of dermatitis or athlete's foot.

When considering drug interactions, it is important to note that the systemic absorption of hydrocortisone and clotrimazole from topical preparations is generally minimal. However, interactions can still occur, especially with prolonged use, application over large surface areas, or use under occlusive dressings which can increase systemic absorption. Patients should be advised to inform their healthcare provider of all medications they are taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Hydrocortisone, being a corticosteroid, may interact with other topical medications that can cause skin irritation or those containing corticosteroids, as this may increase the potential for systemic corticosteroid side effects. Caution is advised when using other topical preparations concurrently, especially those containing alcohol or astringents, which could lead to increased irritation.

Clotrimazole may have interactions with other topical agents that alter the integrity of the skin barrier or those that have a similar antifungal spectrum, as this could either increase the potential for adverse effects or alter the efficacy of the treatment. It is also important to consider the potential for interactions with systemic medications that are metabolized by the liver enzyme CYP3A4, as clotrimazole can inhibit this enzyme, although this is more of a concern with oral or intravenous formulations.

Patients should be advised to avoid the use of occlusive dressings unless directed by a healthcare provider, as this can increase systemic absorption of both hydrocortisone and clotrimazole. Additionally, patients should be instructed to apply the cream only to the affected areas and not to use it more frequently than prescribed.

It is also important to monitor for signs of adrenal suppression in patients using large amounts of hydrocortisone, especially in children or on areas where the skin may be thinner, such as the face, as systemic absorption is more likely in these cases. Signs of adrenal suppression may include tiredness, weakness, nausea, and vomiting.

Lastly, patients should be aware that non-drug therapies such as the use of appropriate moisturizers and avoiding known irritants or triggers for their skin condition can be important adjuncts to the use of this medication.

If you have any questions or require further information regarding the use of Hydrocortisone 2%/Clotrimazole 2% Topical Cream, including potential drug interactions and best practices for application, please reach out to us at Bayview Pharmacy. We are here to ensure the safe and effective use of this medication for our patients.

How Does it Work

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The Hydrocortisone 2%/Clotrimazole 2% Topical Cream is a specially compounded medication that combines the anti-inflammatory properties of hydrocortisone with the antifungal capabilities of clotrimazole. This dual-action cream is designed to treat a variety of dermatological conditions that may involve inflammation and fungal infections.

Hydrocortisone is a corticosteroid that works by reducing the production of substances in the body that cause inflammation and allergic reactions. When applied topically, hydrocortisone can alleviate symptoms such as redness, itching, and swelling. It is particularly effective in managing eczema, psoriasis, contact dermatitis, and other inflammatory skin conditions.

Clotrimazole, on the other hand, is an antifungal agent that combats fungal infections by disrupting the cell membrane of the fungi, ultimately leading to their death. It is commonly used to treat skin conditions like athlete's foot, jock itch, ringworm, and candidiasis. By weakening the fungal cell membrane, clotrimazole halts the growth and spread of the fungus, allowing the skin to heal.

The combination of these two active ingredients in a single cream provides a comprehensive treatment approach for conditions where inflammation is complicated by a fungal infection, or where there is a risk of developing a secondary fungal infection due to compromised skin integrity. The semisolid preparation is dispensed in a pump mechanism, which ensures a hygienic, convenient, and controlled application. This delivery system allows patients to apply the medication directly to the affected area with minimal mess and waste, promoting consistent dosing and adherence to the treatment regimen.

It is important for patients and prescribers to understand that while this cream is effective for localized treatment, it should be used with caution. Prolonged use of topical steroids like hydrocortisone can lead to skin thinning and other side effects, and clotrimazole should not be used in individuals with known sensitivity to the drug or its components. As with any medication, it is crucial to follow the prescribed directions and to monitor the treatment area for signs of improvement or adverse reactions.

If you have any questions about the Hydrocortisone 2%/Clotrimazole 2% Topical Cream or its use in treating specific dermatological conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your skin health.

Other Uses

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The Hydrocortisone 2%/Clotrimazole 2% Topical Cream is primarily formulated for its anti-inflammatory and antifungal properties, making it an effective treatment for a variety of dermatological conditions. In addition to the intended purpose of managing inflammatory skin conditions with a fungal component, such as athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis), the components of this cream can also be useful for other uses.

Hydrocortisone, as a corticosteroid, can be used to alleviate symptoms associated with other inflammatory skin conditions such as eczema, psoriasis, contact dermatitis, and insect bites. Its ability to reduce itching, redness, and swelling makes it a versatile agent for many skin irritations. Meanwhile, clotrimazole, which is an antifungal agent, can be effective in treating yeast infections of the skin, such as those caused by Candida. This combined formulation may also be helpful in complex skin conditions where both inflammation and fungal infections are present or likely to occur.

While not the primary application, some individuals may find temporary relief for seborrheic dermatitis or diaper rash using this formulation. However, due to the presence of a corticosteroid, it is crucial to consult with a healthcare professional before using the topical cream for any off-label uses, especially on sensitive or thin-skinned areas of the body to avoid potential side effects such as skin thinning.

It is important to adhere to prescribing guidelines, as overuse or misuse of corticosteroids can lead to adverse effects, and antifungals should not be used indiscriminately due to the potential for developing resistance. If considering use for conditions beyond those originally intended, patients or prescribers should proceed with caution and seek professional advice. The pump mechanism of the container allows for controlled doses to mitigate the risk of over-application but does not replace the need for informed medical guidance. For personalized advice or to discuss potential other uses of this topical preparation, please reach out to us at Bayview Pharmacy. We are here to provide comprehensive information and support for both patients and healthcare providers.

Frequently Asked Questions

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What is Hydrocortisone 2%/Clotrimazole 2% Topical Cream used for?

This topical cream is used to treat fungal skin infections with associated inflammatory conditions. Hydrocortisone is a corticosteroid that reduces inflammation, itching, and redness, while Clotrimazole is an antifungal agent used to treat fungal infections like athlete's foot, jock itch, and ringworm.

How should I apply Hydrocortisone/Clotrimazole Topical Cream?

Clean and dry the affected area before application. Use the pump to dispense the cream, and apply a thin layer to the affected area, usually twice daily, or as directed by a healthcare professional. Rub in gently.

Can I cover the treated area with a bandage?

Unless advised by a healthcare professional, do not cover the treated area with a bandage or dressing. Covering the area can increase the absorption of the medication, which may lead to unwanted side effects.

How long should I use this cream?

You should use the cream for the duration prescribed by your healthcare provider. Do not stop using the medication early, even if symptoms improve, as the infection may not be fully treated and could return.

What should I do if I miss a dose?

If you miss a dose, apply the cream as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for the missed dose.

Are there any potential side effects?

Possible side effects may include burning, itching, irritation, dryness, or redness at the application site. Report any signs of allergic reactions or other serious side effects, such as severe blistering or peeling skin, to your healthcare provider immediately.

Can I use this cream on my face?

Avoid using this cream on your face unless specifically directed by your healthcare provider. Special caution should be taken when applying near the eyes, nose, or mouth.

Is this cream safe to use during pregnancy or while breastfeeding?

You should consult with your healthcare provider before using this cream if you are pregnant or breastfeeding. They will assess the potential benefits and risks to determine whether this medication is safe for you.

How should this cream be stored?

Store the topical cream at room temperature away from heat and moisture. Do not freeze. Keep the container tightly closed when not in use. Keep out of reach of children and pets.

Can I use other skin products on the same area where I've applied Hydrocortisone/Clotrimazole cream?

Before using other skin products on the same area, consult with your healthcare provider. Other products may affect how Hydrocortisone/Clotrimazole Topical Cream works or increase the risk of side effects.

What is the advantage of using a pump mechanism for dispensing this cream?

The pump mechanism allows for convenient and controlled application of the cream, ensuring appropriate dosage and minimizing waste or contamination of the product.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.