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Formulas

Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream

The Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream is a semisolid preparation that combines the anti-inflammatory and antipruritic properties of hydrocortisone with the antimicrobial action of iodoquinol. This dual-action cream is dispensed in a pump mechanism, which ensures a convenient, hygienic, and controlled application to the affected skin areas. It is specifically formulated for the localized treatment of inflammatory dermatoses that are responsive to corticosteroids, such as eczema and psoriasis, and for the management of skin conditions associated with bacterial or fungal infections. The cream's vehicle is designed to facilitate the absorption of the active ingredients, providing relief from itching, redness, and discomfort, while also helping to inhibit the growth of pathogenic microorganisms.

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Topical Cream
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Formula Information

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The Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream is a compounded medication that combines the anti-inflammatory properties of hydrocortisone with the antimicrobial action of iodoquinol. Hydrocortisone, a corticosteroid, works by reducing inflammation, redness, and swelling in the affected area, making it effective for a variety of dermatological conditions. Iodoquinol, on the other hand, is an antifungal and antibacterial agent that helps to combat infections caused by susceptible organisms. This dual-action cream is particularly useful in treating inflammatory skin conditions that are complicated by a secondary infection or are at risk of becoming infected.

The cream is formulated as a semisolid preparation and is dispensed in a pump mechanism container. This delivery system is designed to provide a convenient and controlled application, ensuring that the correct dose is administered each time. The pump also helps to maintain the sterility of the product, reducing the risk of contamination that can occur with traditional jar packaging. This is especially important for patients with compromised skin barriers, as it minimizes the introduction of potential pathogens.

This Hydrocortisone/Iodoquinol cream is indicated for the treatment of inflammatory dermatoses where bacterial or candidal infection is present, suspected, or likely to occur. Conditions such as eczema, psoriasis, contact dermatitis, and intertrigo may benefit from this formulation. The anti-inflammatory action of hydrocortisone can provide symptomatic relief from itching and discomfort, while iodoquinol addresses the microbial component of these conditions.

Patients should be advised to apply the cream to the affected area as directed by their healthcare provider. It is important to use this medication for the full prescribed treatment period, even if symptoms improve before the medication is finished. Patients should also be informed about potential side effects, which may include skin irritation, dryness, or worsening of symptoms. If any severe reactions occur, they should discontinue use and consult their healthcare provider immediately.

Prescribers considering this formulation for their patients should be aware of the potential for systemic absorption of hydrocortisone, especially with prolonged use or application over large surface areas. Caution should be exercised when prescribing to patients with a history of sensitivity to corticosteroids or iodine-containing compounds. Additionally, the use of occlusive dressings with this cream should be done judiciously, as they may increase the absorption of the active ingredients.

Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the specific needs of patients. If you have any questions about this Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream or would like to discuss its suitability for your patients, please do not hesitate to reach out to us. We are here to support healthcare providers and patients with expert advice and personalized care.

Drug Interactions

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The Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream is a combination medication used for the treatment of inflammatory skin conditions that may also have a bacterial or fungal component. Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness, while iodoquinol is an antifungal and antibacterial agent. When using this topical cream, it is important to consider potential drug interactions.

Hydrocortisone, being a corticosteroid, can interact with other topical medications that may lead to increased systemic absorption and potential adrenal suppression, especially if used over large areas of the body or under occlusive dressings. Patients should avoid using other topical steroids concurrently unless directed by a healthcare provider. Additionally, the use of other skin products such as harsh soaps, cosmetics, or other skin care products on the area of treatment may cause increased irritation or absorption and should be discussed with a healthcare provider.

Iodoquinol, on the other hand, has fewer known drug interactions. However, it is important to note that iodoquinol can interact with thyroid medications due to its iodine content. Patients with thyroid disorders should use this medication cautiously and under the guidance of their healthcare provider. Concurrent use of other antifungal or antibacterial agents should be monitored for increased skin irritation or altered efficacy.

Systemic absorption of hydrocortisone may also be affected by certain medications taken orally, such as CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir), which can potentially increase levels of hydrocortisone leading to systemic side effects. It is essential to inform the healthcare provider of all medications being taken, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

Patients with pre-existing conditions such as liver disease, diabetes, or immune system problems should use this medication with caution, as systemic absorption of hydrocortisone could potentially worsen these conditions. It is also advisable for patients to inform their healthcare provider if they are pregnant, planning to become pregnant, or breastfeeding, as the safety of this medication has not been fully established in these populations.

It is important to use this medication only as directed by a healthcare provider and for the condition for which it was prescribed. Avoid applying the cream to broken or infected skin unless directed to do so by a healthcare provider. If there is no improvement in the skin condition after a prescribed period, or if the condition worsens, patients should contact their healthcare provider.

If you have any questions or concerns regarding the use of Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream or potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure safe and effective treatment.

How Does it Work

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The Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream is a specially formulated medication that combines the anti-inflammatory and antipruritic properties of hydrocortisone with the antimicrobial action of iodoquinol. This cream is designed to be used for the treatment of various dermatological conditions that involve inflammation and bacterial or fungal infections.

Hydrocortisone is a corticosteroid that works by mimicking the effects of hormones naturally produced by the adrenal glands. When applied topically, hydrocortisone acts within the skin cells to decrease the release of inflammatory substances that cause swelling, redness, and itching. This makes it an effective treatment for conditions such as eczema, psoriasis, contact dermatitis, and other types of dermatitis.

Iodoquinol, on the other hand, is a halogenated hydroxyquinoline that possesses antimicrobial properties. It is particularly effective against certain bacteria and fungi, making it useful in treating skin conditions that have a secondary infection or are primarily caused by these microorganisms. Iodoquinol disrupts the microbial cell function, leading to the death of the pathogenic cells.

The combination of hydrocortisone and iodoquinol in a single cream provides a broad-spectrum approach to treating skin conditions that are both inflammatory and infectious in nature. The dual action of the ingredients helps to reduce symptoms such as itching, redness, and scaling, while also eradicating the infectious agents present.

The cream is dispensed in a pump mechanism, which offers several advantages. The pump allows for a more hygienic application, as it minimizes the risk of contamination that can occur with jar packaging. It also provides a convenient and controlled dosage, ensuring that a consistent amount of medication is applied to the affected area each time. This dosage form is particularly beneficial for patients who require a precise application over a localized area of the skin.

For optimal results, the cream should be applied to the affected area as directed by a healthcare provider. It is important to use the medication regularly and for the full prescribed duration, even if symptoms improve before the treatment course is complete. Patients should be advised not to cover the treated area with occlusive dressings unless directed by a physician, as this can increase the absorption of hydrocortisone and potentially lead to systemic side effects.

If you have any questions about the Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream or its use in treating specific dermatological conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your patients' skin health.

Other Uses

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Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream is primarily indicated for the treatment of inflammatory dermatoses that are responsive to corticosteroids, and for which a secondary infection caused by susceptible organisms, including fungi and bacteria, is confirmed or suspected. Besides these conventional indications, the formulation may have additional off-label uses where the combination of an anti-inflammatory corticosteroid and an antimicrobial agent is beneficial.

For instance, the antifungal properties of iodoquinol make this cream potentially useful in managing certain dermatological conditions where a mild corticosteroid is required to address inflammation or itching, coupled with an antifungal component to reduce the risk of secondary infection. However, it is essential to note that the use of corticosteroids—like hydrocortisone—on fungal infections requires precise medical supervision to avoid exacerbating the condition.

Furthermore, due to its anti-inflammatory effects, this formulation may be used in cases of eczema or psoriasis where secondary bacterial infection is a concern. The careful application of the cream could help manage inflammation and prevent or treat superficial infections that often complicate these chronic conditions. It is also conceivable that this cream might be employed to treat minor skin irritations or rashes that exhibit both inflammatory and infectious elements though it should not be used as a first-line treatment without proper dermatological advice.

Patients should be advised that while this hydrocortisone and iodoquinol cream can be useful for various skin conditions, its use should be based on a physician's diagnosis and recommendation to ensure safety and effectiveness. It is also important to highlight that this cream is not intended for ophthalmic, oral, or intravaginal use and its efficacy and safety for use beyond the specified indications have not been established for all possible off-label uses.

As with any medication, the potential for side effects or interactions with other topical or systemic treatments should be carefully considered. Prescribers and patients seeking further information or clarification regarding the possible other uses of Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream are encouraged to reach out to us at Bayview Pharmacy for comprehensive advice tailored to specific patient needs and circumstances.

Frequently Asked Questions

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What is Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream used for?

This topical cream is used for the treatment of inflammatory skin conditions that have a bacterial or fungal component. The hydrocortisone in the cream provides anti-inflammatory benefits, while the iodoquinol acts as an antimicrobial to treat or prevent infection.

How do I use the pump mechanism to dispense the cream?

To use the pump, hold the container upright and press down on the pump. This will dispense a controlled amount of cream. If using for the first time, you may have to press the pump several times to initiate the flow of the cream.

How much cream should I apply?

The amount of cream needed depends on the size of the area being treated. Your healthcare provider will advise you on the correct quantity to use for each application. Always follow the prescribed directions.

Can I use this cream on my face?

While it is possible to use this cream on facial skin if prescribed by your healthcare provider, you should use it with caution, especially around the eyes, nose, and mouth. Be sure to follow your healthcare provider's instructions closely to avoid any potential side effects.

Are there any side effects of using Hydrocortisone 1.25%/Iodoquinol 1.25% Topical Cream?

Like any medication, this topical cream can cause side effects, though not everyone will experience them. Common side effects may include skin irritation, redness, or a burning sensation at the application site. If you experience any severe side effects or signs of an allergic reaction, contact your healthcare provider immediately.

How often should I apply the cream?

The frequency of application will be determined by your healthcare provider based on the condition being treated. It is important to follow their instructions and not exceed the recommended number of applications.

Can I cover the area with a bandage after applying the cream?

Unless advised by your healthcare provider, it is generally not necessary to cover the treated area with a bandage. In some cases, occlusive dressings may be recommended to enhance the medication absorption, but only do so if you have explicit instructions from your healthcare professional.

Should I use this cream if I am pregnant or breastfeeding?

Consult with your healthcare provider before using this cream if you are pregnant or breastfeeding. They will weigh the benefits and potential risks before making a recommendation tailored to your situation.

What should I do if I miss a dose?

If you forget to apply your dose, apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply an extra dose to make up for a missed one.

How should I store this medication?

Store the cream at room temperature, away from direct light and heat. Do not freeze it. Keep the container securely closed when not in use, and keep it out of reach of children and pets.

What should I do in the event of an overdose?

While an overdose is unlikely when applied topically as directed, if you suspect an overdose or experience severe side effects, seek medical attention immediately. Signs of an overdose might involve excessive redness, peeling, or irritation in the area where applied excessively.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.