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Formulas

Hydrocortisone 0.1% Opthalmic Ointment

Hydrocortisone 0.1% Ophthalmic Ointment is a semi-solid formulation intended for external application to the eye area. This ointment is dispensed in a tube and possesses a greasy or oily base, which facilitates the localized delivery of the active ingredient, hydrocortisone. The ointment is specifically designed to treat inflammatory conditions of the eye, such as blepharitis, conjunctivitis, and other allergic or inflammatory reactions affecting the ocular region. Its emollient properties ensure that the medication remains in contact with the affected area for an extended period, promoting healing and providing relief from symptoms associated with these disease states.

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Hydrocortisone
Topical Ointment
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Formula Information

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Hydrocortisone 0.1% Ophthalmic Ointment is a specialized semi-solid formulation designed for external application to the skin around the eyes. This ointment is dispensed in a tube and possesses a greasy or oily base, which not only facilitates the application but also enhances the delivery and absorption of the active ingredient, hydrocortisone. Hydrocortisone is a corticosteroid that functions by reducing inflammation, itching, and redness. It is particularly effective in treating various dermatological conditions such as eczema, psoriasis, allergic reactions, and other types of dermatitis.

The ointment's base provides a protective barrier that not only moisturizes the affected area but also ensures a sustained release of the medication, allowing for prolonged therapeutic effects. This is especially beneficial for conditions that require consistent medication levels for relief and healing. The 0.1% concentration of hydrocortisone in the ointment is considered a low dose, which minimizes the risk of potential side effects that are often associated with higher strengths of topical corticosteroids, such as skin thinning, stretch marks, or systemic absorption leading to corticosteroid-related side effects.

For patients, it is important to apply the ointment as directed by a healthcare professional, typically to the affected area around the eyes, avoiding direct contact with the eyes. The area should be clean and dry before application. Patients should be advised to use the ointment for the duration prescribed and not to discontinue use abruptly without consulting their healthcare provider, as this may lead to a rebound effect of the condition. Prescribers should consider the patient's medical history, including any known hypersensitivities or pre-existing eye conditions, before recommending this formulation.

Hydrocortisone 0.1% Ophthalmic Ointment is contraindicated in individuals with viral, fungal, or bacterial eye infections unless an appropriate anti-infective agent is used concurrently. It is also not recommended for use in individuals with glaucoma, as corticosteroids can increase intraocular pressure. Long-term use should be monitored for potential side effects, and patients should be educated on the signs of potential adverse reactions.

As compounding pharmacists at Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the specific needs of our patients. We are available to answer any questions and provide additional information to both patients and prescribers regarding the use of Hydrocortisone 0.1% Ophthalmic Ointment. Please feel free to reach out to us for further assistance.

Drug Interactions

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Hydrocortisone 0.1% Ophthalmic Ointment is a corticosteroid formulation intended for the treatment of inflammatory conditions of the eye. It is important to note that while this ointment is designed for ophthalmic use, the description provided suggests an application to the skin, which may be a typographical error. Assuming the intended use is for ophthalmic purposes, the following drug interaction information is relevant.

When using hydrocortisone ophthalmic ointment, it is crucial to consider potential interactions with other medications. Concurrent use of other corticosteroids, whether systemic or topical, may increase the risk of systemic corticosteroid effects, such as suppressed immune response, adrenal suppression, or Cushing's syndrome. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements.

Patients using ophthalmic preparations containing anti-infectives or other anti-inflammatory agents should be monitored for possible additive effects and adjusted dosages accordingly. The use of hydrocortisone with nonsteroidal anti-inflammatory drugs (NSAIDs) in the eye may increase the potential for healing problems or corneal perforation in diseases causing thinning of the cornea.

Hydrocortisone may also interact with medications that induce cytochrome P450 (CYP) enzyme activity, as these enzymes can metabolize corticosteroids leading to decreased efficacy. Conversely, drugs that inhibit CYP enzymes may increase hydrocortisone levels and its potential side effects. Caution is advised when using hydrocortisone with CYP3A4 inhibitors such as ketoconazole, itraconazole, and ritonavir.

It is also important to consider the potential for interactions with vaccines. The use of hydrocortisone ophthalmic ointment may reduce the efficacy of live or live-attenuated vaccines due to its immunosuppressive effects. Additionally, the use of this medication in patients with ocular herpes simplex may exacerbate the condition.

Hydrocortisone ophthalmic ointment treats inflammation by suppressing the immune response and reducing the production of substances that cause inflammation. It is used in various eye conditions, such as allergic reactions, inflammation, and swelling. However, it is not typically used for infections or wound healing unless combined with an appropriate anti-infective agent, as corticosteroids can mask symptoms of infection and delay healing.

Patients should be advised to avoid wearing contact lenses during treatment with hydrocortisone ophthalmic ointment unless otherwise directed by a healthcare provider. They should also be informed about the potential for temporary visual blurring after application and to avoid activities requiring clear vision until their vision is fully clear.

For any questions or concerns regarding the use of Hydrocortisone 0.1% Ophthalmic Ointment, or to report any adverse effects or suspected drug interactions, healthcare providers and patients are encouraged to reach out to us at Bayview Pharmacy for further assistance and guidance.

How Does it Work

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Hydrocortisone 0.1% Ophthalmic Ointment is a semi-solid formulation specifically designed for application to the eye area. This ointment is dispensed in a tube and is intended for external use only. The base of the ointment is greasy or oily, which not only facilitates the delivery of the active medication, hydrocortisone, to the affected area but also provides a protective layer that can help to soothe and heal the eye's surface. Hydrocortisone is a corticosteroid, which means it is a steroid medication that works by reducing inflammation and suppressing the immune response in the area where it is applied.

The mechanism of action of hydrocortisone involves its interaction with steroid receptors in the cells. Once hydrocortisone binds to these receptors, it leads to changes in the transcription of certain genes, particularly those involved in the inflammatory response. By doing so, it decreases the production of inflammatory chemicals like cytokines and chemokines, and reduces the activity of immune cells that contribute to inflammation. This results in a decrease in swelling, redness, and pain in the area where the ointment is applied.

Hydrocortisone 0.1% Ophthalmic Ointment is typically used to treat inflammatory conditions of the eye, such as blepharitis, conjunctivitis, and certain allergic reactions. It can also be used to manage inflammation following eye surgery or injury. By reducing inflammation, hydrocortisone can help alleviate symptoms such as itching, redness, and swelling, and promote a more comfortable healing process. It is important to note that while hydrocortisone is effective in treating these symptoms, it is not an antibiotic and does not treat bacterial infections. If an infection is present, additional medication may be required.

Patients and prescribers should be aware that the use of hydrocortisone ophthalmic ointment should be under the guidance of a healthcare professional, as improper use can lead to side effects or exacerbation of certain conditions. It is also crucial to use this medication only for the prescribed duration and not to discontinue it abruptly without consulting a healthcare provider. If you have any questions or concerns about the use of Hydrocortisone 0.1% Ophthalmic Ointment, please reach out to us at Bayview Pharmacy for further assistance.

Other Uses

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Please note that the description you have provided is for a topical skin ointment, rather than an ophthalmic ointment which would be used in the eyes. Assuming that we are discussing a hydrocortisone 0.1% skin ointment formulation, this versatile medication has various applications beyond just treating skin inflammation, infections, or wound healing. This concentration of hydrocortisone is typically used for its anti-inflammatory and immunosuppressive properties.

Hydrocortisone ointment can also be beneficial in managing eczema, psoriasis, and dermatitis by reducing itching, redness, and swelling. In addition, it can be used to treat insect bites or stings, contact dermatitis resulting from exposure to irritants or allergens, and to alleviate discomfort associated with minor rashes. Rarely, it may be used to manage certain kinds of psoriasis that do not involve extensive areas of the body due to the potential risks of systemic absorption with long-term use. It is important to note that while hydrocortisone ointment can relieve symptoms caused by these conditions, it does not cure the underlying causes. Therefore, patients might require ongoing treatment or a combination of medications to manage their condition effectively.

Patients should be advised to apply the ointment sparingly to the affected area following the specific directions provided by the prescriber or the directions on the label, keeping in mind not to use it on the face, groin, or underarms unless directed by a healthcare provider. It is also important to be aware that this formulation should not be used on open wounds or on areas of infection without direct recommendation from a healthcare professional. Additionally, it is not to be ingested or applied to the eyes. Long-term use or application over large surface areas should be avoided due to potential systemic absorption and subsequent side effects such as adrenal suppression.

Prescribers should regularly review the patient's condition, especially if the ointment is intended for chronic use. Dose adjustments may be necessary depending on the patient's response and the presence of side effects, and alternative treatments should be considered if side effects become bothersome or if there is a lack of significant improvement. For both prescribers and patients, awareness of the full range of potential uses and precautions will help ensure the safe and effective application of hydrocortisone 0.1% ointment. If you have any questions regarding the formulation, its uses, or if you want individualized advice on treatment options, please feel free to reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Hydrocortisone 0.1% Ophthalmic Ointment used for?

Hydrocortisone 0.1% Ophthalmic Ointment is used primarily to treat inflammatory conditions of the eye, such as swelling, redness, and itching. It can also be prescribed for certain eye infections and during post-operative care to reduce discomfort and promote healing.

How should I apply Hydrocortisone 0.1% Ophthalmic Ointment?

Wash your hands thoroughly before applying the ointment. Apply a small amount of the ointment to the affected eye, typically inside the lower eyelid, as directed by your healthcare provider. Do not let the tip of the tube touch your eye or other surfaces to avoid contamination.

Can Hydrocortisone 0.1% Ophthalmic Ointment cause any side effects?

Like all medications, Hydrocortisone 0.1% Ophthalmic Ointment can cause side effects, although not everyone gets them. Common side effects may include temporary blurred vision, mild eye irritation or discomfort, and increased pressure in the eye. If you experience any severe or persistent side effects, consult your healthcare provider immediately.

How often should I use Hydrocortisone 0.1% Ophthalmic Ointment?

The frequency of application will depend on the condition being treated and the instructions provided by your healthcare provider. Do not use it more often or for a longer period than recommended as this can increase the risk of side effects.

Can Hydrocortisone 0.1% Ophthalmic Ointment be used on other parts of the body?

This particular formulation is meant for ophthalmic use and should only be applied to the eye area as prescribed. If you require treatment for other areas of the skin, consult a healthcare professional for an appropriate formulation and guidance.

What should I do if I accidentally get Hydrocortisone 0.1% Ophthalmic Ointment in my mouth or ingest it?

If you accidentally ingest the ointment, contact a healthcare professional or poison control center immediately for advice. Do not induce vomiting unless instructed to do so by a medical professional.

What storage conditions are required for Hydrocortisone 0.1% Ophthalmic Ointment?

Store the ointment at room temperature away from direct light and heat. Keep the tube tightly closed when not in use and keep it out of reach of children and pets.

Should I wear contacts while using Hydrocortisone 0.1% Ophthalmic Ointment?

It is generally advised not to wear contact lenses during treatment with Hydrocortisone 0.1% Ophthalmic Ointment, especially if you are treating an eye infection. Consult your healthcare provider for specific advice related to your treatment and the use of contact lenses.

Can I use makeup or other cosmetic products around my eyes while using this ointment?

It's best to avoid using makeup or other cosmetic products around the eyes while using Hydrocortisone 0.1% Ophthalmic Ointment to prevent contamination and ensure proper healing. Discuss any specific concerns with your healthcare provider.

What should I do if I miss a dose of Hydrocortisone 0.1% Ophthalmic Ointment?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double up to make up for a missed dose.

Can children use Hydrocortisone 0.1% Ophthalmic Ointment?

Use in children should be under the guidance of a healthcare provider. Dosage and duration of treatment may differ due to children's differing responses to medication and the severity of their condition.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.