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Formulas

Glycolic Acid 25% Topical Cream

The Glycolic Acid 25% Topical Cream is a semisolid preparation formulated for targeted application on the skin. This cream is dispensed through a pump mechanism, which ensures convenient, controlled, and hygienic delivery of the active ingredient. Glycolic acid, as an alpha hydroxy acid (AHA), is commonly used for its exfoliating properties. This particular concentration is designed to treat a variety of dermatological conditions, including acne, photoaging, hyperpigmentation, and rough skin texture. By promoting the shedding of the outer layer of skin cells, it reveals the newer, more evenly pigmented skin layers beneath and stimulates collagen production, leading to a smoother and more youthful appearance. Regular use as directed can improve skin clarity, texture, and tone.

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Topical Cream
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Formula Information

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Glycolic Acid 25% Topical Cream is a specially formulated dermatological agent, designed to provide a high concentration of glycolic acid in a semisolid cream base for topical application. Glycolic acid, an alpha hydroxy acid (AHA), is widely recognized for its exfoliating properties, which help to promote the shedding of the outermost layer of dead skin cells. This action can lead to smoother skin texture, improved skin tone, and a reduction in the appearance of fine lines and wrinkles. The 25% concentration of glycolic acid in this cream is considered a high-strength formulation, typically used for more pronounced skin concerns under the guidance of a healthcare professional.

The cream is dispensed in a pump mechanism, which offers several advantages for both patients and prescribers. The pump allows for controlled dosing, reducing the risk of over-application, and it also helps to protect the integrity of the product by minimizing exposure to air and contaminants. This delivery system is particularly beneficial for maintaining the stability of glycolic acid, which can be sensitive to oxidation. The semisolid cream base is designed to facilitate absorption of the active ingredient while providing a moisturizing effect, enhancing patient comfort during treatment.

Glycolic Acid 25% Topical Cream is indicated for various skin conditions where accelerated exfoliation is desired. It is commonly used in the management of acne, as it can help to unclog pores and reduce the formation of acne lesions. Additionally, it is effective in treating hyperpigmentation, including age spots and melasma, by promoting the removal of pigmented skin cells. The cream may also be used in the treatment of keratosis pilaris, a condition characterized by rough, bumpy skin, as it helps to smooth the skin's surface. Furthermore, it is utilized in anti-aging regimens to diminish the signs of photoaging by stimulating collagen production and improving skin elasticity.

It is important for patients and prescribers to be aware that while Glycolic Acid 25% Topical Cream can offer significant benefits, it may also cause side effects such as skin irritation, redness, and increased sensitivity to sunlight. Therefore, it should be used with caution, and sun protection measures should be advised during treatment. Patients with sensitive skin or certain skin conditions should consult with a healthcare provider before using this product. Additionally, this formulation should be used as part of a comprehensive skin care plan, potentially including other topical or systemic therapies as directed by a healthcare professional.

For more detailed information on Glycolic Acid 25% Topical Cream, or if you have any questions regarding its use, formulation, or compatibility with other treatments, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing expert guidance and support to ensure the safe and effective use of our compounded medications.

Drug Interactions

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Glycolic acid is an alpha hydroxy acid (AHA) commonly used in dermatology for its exfoliating properties. It works by breaking down the substance that holds dead skin cells on the surface, promoting exfoliation and stimulating new cell growth. This action can help in the treatment of various skin conditions, including acne, photoaging, hyperpigmentation, and keratosis pilaris. While glycolic acid is generally considered safe for topical use, it is important to be aware of potential drug interactions when using this 25% topical cream formulation.

When using glycolic acid 25% topical cream, it is crucial to consider its potential interaction with other topical treatments. Concurrent use with other exfoliating agents, such as retinoids, salicylic acid, or other AHAs, may increase the risk of skin irritation, redness, and peeling. It is advisable to avoid using multiple exfoliating products simultaneously unless directed by a healthcare provider. Additionally, products containing alcohol or astringents may exacerbate skin dryness or irritation when used with glycolic acid.

Patients should also be cautious when using glycolic acid with medications that increase photosensitivity. These include certain antibiotics (such as tetracyclines), thiazide diuretics, sulfonylureas, phenothiazines, and some other acne medications like isotretinoin. Using glycolic acid can make the skin more susceptible to sunburn, and combining it with photosensitizing drugs may further increase this risk. It is essential to apply a broad-spectrum sunscreen and limit sun exposure while using this formulation.

It is important to note that while glycolic acid is primarily for external use, caution should be exercised when used near the eyes, mucous membranes, or on broken or inflamed skin. The high concentration of glycolic acid in this formulation may lead to increased absorption and the potential for systemic effects, although this is rare. Patients with sensitive skin or those using glycolic acid for the first time should start with a lower concentration to assess skin tolerance.

For patients undergoing cosmetic procedures, such as chemical peels or laser treatments, it is recommended to discontinue the use of glycolic acid 25% topical cream prior to the procedure to reduce the risk of excessive skin irritation or damage. The healthcare provider performing the procedure should be informed of all topical treatments the patient is currently using.

As with any medication, it is essential to consult with a healthcare provider before starting new treatments or combining them with existing ones. If you have any questions or concerns about using glycolic acid 25% topical cream or its interactions with other drugs, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure safe and effective treatment outcomes.

How Does it Work

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Glycolic acid is an alpha hydroxy acid (AHA) derived from sugar cane and is widely recognized for its use in skincare treatments. As a 25% topical cream, glycolic acid works by exfoliating the uppermost layer of the skin, which helps to shed dead skin cells and reveal the newer, more evenly pigmented skin cells beneath. This concentration of glycolic acid is considered a high-strength formulation and is typically used for more intensive skin treatments.

The mechanism of action of glycolic acid involves the breaking down of the substance that holds dead skin cells together on the surface of the skin. By penetrating the upper layer of the skin, glycolic acid weakens the binding properties of the lipids that hold the dead skin cells together. This allows the outer skin to dissolve, promoting exfoliation. The result is smoother, brighter, and more evenly toned skin. Additionally, glycolic acid has been shown to stimulate collagen production, which can lead to firmer and more youthful-looking skin over time.

In terms of disease states, glycolic acid 25% topical cream is primarily used to treat conditions such as acne, photoaging, hyperpigmentation, and keratosis pilaris. For acne, glycolic acid helps to unclog pores and reduce the appearance of acne scars by accelerating the turnover of skin cells. When addressing photoaging, the cream can diminish the appearance of fine lines and wrinkles by promoting new collagen formation. For hyperpigmentation issues like melasma or age spots, glycolic acid can help lighten dark patches by removing the upper layer of pigmented skin cells. Lastly, in the case of keratosis pilaris, it can help to smooth the skin by reducing the buildup of keratin that causes the formation of rough bumps.

The semisolid preparation of this glycolic acid cream is designed to be dispensed in a pump mechanism. This type of packaging ensures that the product is protected from air and light, which can degrade the effectiveness of glycolic acid. The pump also allows for controlled and hygienic application, reducing the risk of contamination and ensuring that the correct dose is applied to the skin. Patients should apply the cream as directed by their healthcare provider, typically once daily or as tolerated, and it is important to use sunscreen during the day while using this product due to increased photosensitivity.

It is essential for both patients and prescribers to be aware that while glycolic acid is generally safe, it can cause side effects such as redness, peeling, and irritation, particularly at higher concentrations. A patch test is recommended before widespread use to ensure that the patient does not have an adverse reaction to the cream. Additionally, prescribers should consider the patient's skin type, the presence of any skin conditions, and their overall skin care regimen when recommending this formulation.

If you have any questions or require further information about the glycolic acid 25% topical cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this formulation.

Other Uses

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Glycolic acid 25% topical cream is primarily recognized for its benefits in the area of dermatology, where it is used to improve skin texture and tone, manage acne, and reduce the appearance of fine lines and hyperpigmentation. However, the efficacy of glycolic acid extends beyond these uses, positioning it as a versatile component in skin care regimens for a variety of skin conditions. Additionally, due to its exfoliative properties, glycolic acid can be employed as a preparatory treatment to enhance the penetration and effectiveness of other topical medications, acting as a skin priming agent. This mechanism can be particularly useful in facilitating the absorption of other topical treatments for disease states such as psoriasis or keratosis pilaris, where a buildup of keratinized skin cells occurs.

Beyond its exfoliative action, glycolic acid displays excellent moisturizing properties due to its small molecular size, which allows it to penetrate the skin and attract water molecules to the area, promoting hydration. It is also found to aid in the management of ingrown hairs by promoting the shedding of dead skin cells and clearing follicular obstruction. Moreover, some studies suggest potential use in the maintenance of a healthy skin barrier, which might be beneficial for individuals experiencing conditions associated with impaired barrier function, such as eczema or certain age-related changes.

When considering the use of glycolic acid 25% topical cream in a semisolid preparation with a pump mechanism, it is important for patients and prescribers to understand that while its applications may be diverse, the high concentration of glycolic acid calls for careful consideration and potentially gradual introduction into the treatment regimen, to assess individual skin tolerance and avoid irritation. It is vital to follow up with sunscreen after application due to increased photosensitivity associated with its use, and it is generally recommended to apply the product in the evening. For patients with a desire to explore the expanded use of this formulation or seeking guidance on integration with other treatments, consulting a dermatologist or healthcare provider is advisable. If you have any questions regarding the preparation, possible additional uses, or its suitability for a specific condition, please do not hesitate to reach out to us at Bayview Pharmacy for personalized advice and assistance.

Frequently Asked Questions

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What is Glycolic Acid 25% Topical Cream used for?

Glycolic Acid 25% Topical Cream is primarily used for exfoliating the skin, improving skin texture and tone, and reducing signs of aging such as fine lines and wrinkles. It may also help with acne, hyperpigmentation, and uneven skin tone.

How should I apply Glycolic Acid 25% Topical Cream?

Cleanse your skin and pat it dry. Use the pump mechanism to dispense a small amount of cream onto your fingers. Apply a thin layer of the cream to the affected area of the skin. Avoid sensitive areas such as the eyes, lips, and mucous membranes. Wait for the cream to fully absorb before applying any other products.

How often can I use Glycolic Acid 25% Topical Cream?

Your dermatologist will advise you on the frequency of use based on your skin type and condition. Generally, it is advised to start with less frequent applications and gradually increase as tolerated, potentially ranging from once every other day to daily use in the evening.

Can I use makeup after applying Glycolic Acid 25% Topical Cream?

Yes, you can use makeup after the cream is fully absorbed into your skin. However, it's recommended to wait a few minutes to ensure the product has fully penetrated the skin's surface.

Should I use sunscreen while using this cream?

Absolutely. Glycolic acid can increase your skin's sensitivity to the sun. You should use a broad-spectrum sunscreen with an SPF of 30 or higher during the day while using this cream and for a week after discontinuation.

What should I do if I experience irritation or discomfort?

If you experience significant irritation, redness, or discomfort, discontinue use of the cream and consult your healthcare provider. You may need to reduce the frequency of application or switch to a lower concentration if appropriate.

Can I use this cream on my body?

While Glycolic Acid 25% Topical Cream is generally meant for facial use, it can potentially be applied to other areas of the body affected by rough texture or discoloration. Speak with your healthcare provider to determine if this is appropriate for you.

What should I do if I accidentally apply too much cream?

If you've applied too much cream, remove the excess with a tissue or damp cloth and rinse the area with water. Monitor your skin for any adverse reactions and use the product more sparingly in future applications.

How should I store Glycolic Acid 25% Topical Cream?

Store the cream at room temperature away from direct sunlight and heat to preserve its potency and stability. Ensure the cap is tightly closed to avoid unnecessary exposure to air.

Can I combine Glycolic Acid 25% Topical Cream with other skin treatments?

Some skin treatments may interact with glycolic acid, so it's important to consult your dermatologist before combining it with other products, especially those containing retinol, vitamin C, or other acids.

Is Glycolic Acid 25% Topical Cream suitable for all skin types?

While many individuals can benefit from the use of glycolic acid, those with sensitive skin may be more prone to irritation. It's important to conduct a patch test and consult with a healthcare provider to determine suitability for your skin type.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.