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Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream

The Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream is a specialized dermatological formulation intended for the treatment of hyperpigmentation, melasma, and age spots. This cream combines the antioxidant properties of Glutathione, the skin barrier-enhancing effects of Niacinamide, and the melanin synthesis-inhibiting action of Tranexamic Acid to provide a multifaceted approach to skin discoloration. The semisolid preparation is housed in a pump mechanism, ensuring that each application is hygienic, convenient, and delivers a controlled dose to the affected area for optimal efficacy.

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Topical Cream
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Formula Information

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Our custom-compounded Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream is a specialized dermatological preparation designed to address a variety of skin concerns. This unique formulation combines the antioxidant properties of Glutathione, the skin barrier-enhancing effects of Niacinamide, and the pigmentation-correcting abilities of Tranexamic Acid. The cream is presented in a semisolid form, which is dispensed through a pump mechanism to ensure a hygienic, convenient, and controlled application. This delivery system allows for precise dosing and helps maintain the stability of the active ingredients.

Glutathione, a potent antioxidant, plays a crucial role in detoxifying the skin and protecting it from oxidative stress, which can lead to premature aging and skin damage. It also has a brightening effect on the skin, which can help to reduce the appearance of dark spots and improve overall skin tone. Niacinamide, also known as Vitamin B3, has been shown to strengthen the skin's barrier function, reduce inflammation, and regulate oil production, making it beneficial for a wide range of skin types and conditions, including acne and eczema. Lastly, Tranexamic Acid is recognized for its ability to diminish the appearance of discoloration and melasma by inhibiting the production of melanin, the pigment responsible for skin color.

This compounded cream is particularly suited for patients seeking to improve the appearance of hyperpigmentation, melasma, and post-inflammatory hyperpigmentation (PIH), as well as those looking to enhance overall skin texture and tone. The combination of these three active ingredients in one formulation provides a multifaceted approach to skin care, targeting several pathways involved in skin discoloration and aging.

It is important for both patients and prescribers to understand that this topical cream should be used as directed by a healthcare professional, and it is essential to adhere to the prescribed regimen to achieve the best results. As with any topical treatment, users should monitor their skin for any signs of irritation or adverse reactions and report these to their healthcare provider immediately. Additionally, patients should be advised to use sun protection while using this product, as some ingredients may increase the skin's sensitivity to sunlight.

For further information, guidance on usage, or to discuss whether this formulation is appropriate for your specific skin concerns, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of expert compounding pharmacists is dedicated to providing personalized care and support to ensure optimal treatment outcomes.

Drug Interactions

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The topical cream formulation containing Glutathione 15%, Niacinamide 2%, and Tranexamic Acid 10% is designed for localized skin treatment and may offer benefits for various skin conditions such as hyperpigmentation, melasma, and inflammation. However, it is important to consider potential drug interactions when using this formulation, especially if the patient is using other topical or systemic medications.

Glutathione, a potent antioxidant, is generally considered safe for topical use and has minimal systemic absorption. However, patients should be cautious if they are taking other skin-lightening agents or antioxidants, as there may be an additive effect that could potentially lead to skin irritation or hypersensitivity reactions. It is also advisable to avoid concurrent use with oxidative therapies, such as peroxide-containing products, as they may reduce the efficacy of glutathione.

Niacinamide, also known as vitamin B3, is well-tolerated when used topically and has a low risk of interactions. However, patients should be aware that niacinamide may potentiate the effects of other anti-inflammatory or anti-aging agents. It is also important to note that niacinamide may cause flushing and irritation when used in conjunction with topical retinoids or high concentrations of vitamin C. Patients should consult with their healthcare provider before combining such treatments.

Tranexamic Acid is primarily known for its antifibrinolytic properties when used systemically, but when applied topically, it is used for its skin-lightening effects. While systemic absorption is low, patients on oral anticoagulants or antiplatelet agents should use this product with caution, as there is a theoretical risk of increased bleeding. Additionally, concurrent use with other skin-lightening agents may increase the risk of skin irritation or dermatitis.

Patients should also be advised to use sunscreen and limit sun exposure while using this formulation, as the active ingredients may make the skin more sensitive to UV radiation. It is also recommended to avoid using this cream on broken or abraded skin to prevent systemic absorption and potential interactions.

Overall, while this topical formulation is designed for localized treatment with minimal systemic exposure, it is still crucial for patients and prescribers to be aware of potential interactions with other medications and skin care products. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream is a specially compounded formulation designed to address a variety of skin concerns, including hyperpigmentation, melasma, and inflammation. This cream is a semisolid preparation that is dispensed in a pump mechanism, which allows for convenient, hygienic, and controlled application. The pump ensures that the correct dose is administered each time, minimizing waste and ensuring consistency in the amount of product used.

Glutathione is a potent antioxidant naturally found in the body. In this topical formulation, at a concentration of 15%, it functions to reduce oxidative stress in the skin. This can help to diminish the appearance of dark spots and improve overall skin tone by inhibiting the production of melanin, the pigment responsible for skin color. Glutathione's antioxidant properties also protect the skin from damage caused by free radicals, which can contribute to aging and skin inflammation.

Niacinamide, also known as Vitamin B3, is included at a 2% concentration. Niacinamide has been shown to have multiple benefits for the skin. It helps to improve the skin's barrier function, retaining moisture and protecting against environmental damage. Additionally, niacinamide has anti-inflammatory properties that can help reduce redness and blotchiness. It also works to regulate sebum production, which can be beneficial for acne-prone skin. Furthermore, niacinamide can help to lighten skin discolorations by inhibiting the transfer of melanosomes from melanocytes to keratinocytes, thereby reducing hyperpigmentation.

Tranexamic Acid is present at a 10% concentration and is a key ingredient for treating melasma and other forms of hyperpigmentation. It is a synthetic derivative of the amino acid lysine and works by inhibiting plasmin, which is an enzyme that can trigger pathways leading to increased melanin production. By preventing this process, tranexamic acid helps to reduce the appearance of existing dark spots and prevents new ones from forming. It also has anti-inflammatory properties that can help to calm the skin and reduce redness.

This combination of active ingredients makes the Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream a powerful tool in the management of skin discoloration and inflammation. It is important to note that while this cream can be highly effective, results may vary among individuals, and consistent use as directed by a healthcare professional is necessary to achieve the best outcomes. As with any topical treatment, it is essential to use sunscreen during the day to protect the skin from UV radiation and prevent further pigmentation issues.

For patients and prescribers interested in using this formulation, it is recommended to discuss the patient's specific skin concerns and medical history to ensure the suitability of this cream for their condition. If you have any questions or require further information about this compounded formulation, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide guidance and support.

Other Uses

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The Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream formulated at Bayview Pharmacy is primarily used for its beneficial effects on skin health. While this formulation is often prescribed for its role in improving hyperpigmentation, reducing the appearance of age spots, and evening out skin tone, it also offers a range of other potential uses that may be of interest to both patients and prescribers. For instance, glutathione is known for its antioxidant properties, which can help combat oxidative stress and may be beneficial in the management of skin affected by environmental aggressors, such as pollution and UV radiation. This could thereby aid in the prevention of premature aging and maintaining healthy skin. Niacinamide, a form of vitamin B3, not only helps with hyperpigmentation but also has anti-inflammatory properties, making it useful in the treatment of acne and improving the appearance of fine lines and wrinkles by reinforcing the skin's barrier function. Tranexamic Acid is an agent known for its ability to minimize the appearance of melasma and is also used to calm the skin and reduce redness, which may be particularly beneficial for those with sensitive or reactive skin conditions.

Moreover, the unique combination of these three active ingredients in a topical cream with a pump mechanism allows for a consistent and hygienic application, ensuring that the correct dosage is applied. This could be advantageous for individuals with skin conditions that require precise treatment regimens. However, it is important to note that while there are various potential benefits associated with the ingredients in this formulation, its effectiveness and appropriateness for use in treating other skin conditions should be discussed with a healthcare provider. The formulation's properties and the concentration of the active ingredients may not be suitable for everyone and could interact with other skin care products or medications.

We are happy to address any questions or provide further consultation on the potential applications of this formulation, ensuring both patients and prescribers have the necessary information for its optimal use. If you have any questions or need specific advice related to this formulation or its other potential uses, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of experienced compounding pharmacists is dedicated to providing personalized care and support to our patients and the healthcare community.

Frequently Asked Questions

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What is the purpose of using Glutathione 15%/Niacinamide 2%/Tranexamic Acid 10% Topical Cream?

This topical cream combines the actions of glutathione, niacinamide, and tranexamic acid. Glutathione is an antioxidant that may help to reduce oxidative stress in the skin. Niacinamide can improve skin barrier function and reduce the appearance of skin blemishes, while tranexamic acid is often used to address skin discoloration and improve skin tone. Combined, they may offer synergistic effects for enhancing skin appearance and health.

How should this topical cream be applied to the skin?

To apply the cream, use the pump mechanism to dispense a small amount onto your fingertips. Gently massage it into the affected area until it's fully absorbed. This should be done following the dosing instructions provided by your healthcare provider, usually once or twice a day.

Can this formulation be used on all skin types?

While this formulation is designed to be used by most skin types, individual skin sensitivities and conditions can vary. It's important to start with a patch test and consult with your dermatologist or healthcare provider before beginning any new topical treatment, especially if you have sensitive skin or a pre-existing skin condition.

Is it necessary to use sunscreen when applying this topical cream?

Yes, it is highly recommended to apply sunscreen when using this cream, especially since active ingredients like niacinamide and tranexamic acid may make your skin more sensitive to sunlight. Use a broad-spectrum sunscreen with an SPF of 30 or higher to protect your skin from sun damage.

Can this cream be used with other skincare products?

It can generally be used alongside other skincare products, but it's essential to be mindful of possible interactions. Wait for the cream to fully absorb before applying other products, and consult with a dermatologist if you're unsure about compatibility, particularly with other active ingredients.

Does this compounded formulation have any known side effects?

As with any skincare product, some individuals may experience side effects. These can include skin irritation, redness, itching, or allergic reactions. If any of these occur, discontinue use and consult your healthcare provider.

How long does it take to see results from using this topical cream?

Results can vary based on individual skin types and conditions. Some people may notice improvements within a few weeks, while for others, it may take longer. Consistent application as directed is important for achieving the best outcomes.

What should be done if I miss a dose?

If you miss an application, apply the cream as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra cream to make up for a missed dose.

How should this cream be stored?

Store the cream at room temperature, away from direct sunlight and heat. Keep the pump tightly closed when not in use to maintain the efficacy of the product. Do not freeze the cream, as this can alter its properties.

Is this topical formulation available over-the-counter?

This specific compounded formulation is not available over-the-counter and requires a prescription from a licensed healthcare provider. It is custom-made based on individual patient needs and is dispensed by a compounding pharmacy.

Can I use this cream if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should consult with your healthcare provider before using this formulation. Some ingredients may not be recommended during pregnancy or nursing, and your provider can advise you on safe alternatives.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.