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Formulas

Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream

Our Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream is a specially formulated semisolid preparation, designed to deliver a potent combination of antioxidants and skin-brightening agents directly to the affected areas. Encased in a pump mechanism, this cream ensures a convenient, hygienic, and controlled application, promoting consistent dosing and ease of use. This topical cream is primarily indicated for the treatment of melasma and hyperpigmentation, conditions characterized by darkened patches of skin. The synergistic effects of glutathione and tranexamic acid work to reduce melanin production, lighten skin tone, and improve overall skin appearance, providing patients with a targeted approach to managing these dermatological concerns.

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Topical Cream
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Formula Information

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Our Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream is a specially compounded formulation that combines the antioxidant properties of Glutathione with the skin-lightening and anti-inflammatory effects of Tranexamic Acid. This cream is designed to be dispensed in a pump mechanism, which ensures a hygienic, convenient, and controlled application. The semisolid preparation is intended for topical use, allowing for localized treatment and facilitating the absorption of the active ingredients directly through the skin.

Glutathione, a naturally occurring antioxidant, is known for its role in protecting cells from oxidative stress and free radicals. In skincare, it is used for its potential to lighten skin pigmentation and improve skin tone by inhibiting the production of melanin. Tranexamic Acid, on the other hand, is a synthetic derivative of the amino acid lysine and is commonly used for its ability to treat melasma and hyperpigmentation. It works by reducing the activity of tyrosinase, an enzyme involved in the production of melanin, and by minimizing the appearance of discolored skin patches.

The combination of Glutathione and Tranexamic Acid in our topical cream formulation provides a dual approach to managing skin discoloration and improving overall skin appearance. It may be particularly beneficial for patients seeking treatment for conditions such as melasma, post-inflammatory hyperpigmentation, and age spots. The cream's formulation is also designed to minimize irritation, making it suitable for sensitive skin types.

For optimal results, patients should apply the cream as directed by their healthcare provider, typically to the affected areas of the skin. It is important to use this product under the guidance of a healthcare professional who can monitor its effectiveness and any potential side effects. As with any topical treatment, patients should be advised to avoid excessive sun exposure and to use sun protection while using this product to prevent further skin damage.

Prescribers considering this formulation for their patients can expect a product that is tailored to address specific skin concerns with the combined benefits of two active ingredients. The cream's base is designed to enhance the stability and delivery of Glutathione and Tranexamic Acid, ensuring that patients receive the full therapeutic potential of the formulation.

If you have any questions or require further information about our Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and prescribers.

Drug Interactions

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The combination of Glutathione and Tranexamic Acid in a topical cream formulation is designed for localized treatment and may be used for various skin conditions, including hyperpigmentation and melasma. Glutathione is an antioxidant that can reduce oxidative stress and has skin-lightening properties by inhibiting the enzyme tyrosinase, which is involved in melanin production. Tranexamic Acid is a synthetic derivative of the amino acid lysine and works by inhibiting plasminogen activator and plasmin, which can indirectly reduce melanin synthesis and has been shown to improve melasma and other pigmentation disorders.

When considering drug interactions, it is important to note that the systemic absorption of both Glutathione and Tranexamic Acid from a topical cream is expected to be minimal. However, interactions can still occur, particularly with Tranexamic Acid, which has antifibrinolytic properties. Patients who are on anticoagulant or antiplatelet medications, such as warfarin, heparin, aspirin, or clopidogrel, should use this cream with caution, as there may be an increased risk of bruising or bleeding, especially if the cream is applied to large areas of skin or to skin that is broken or abraded.

Additionally, Tranexamic Acid may interact with hormonal medications, such as oral contraceptives or hormone replacement therapy, potentially increasing the risk of thromboembolic events, although this risk is likely to be low with topical application. Patients with a history of thromboembolic disease should consult their healthcare provider before using this cream.

Glutathione may interact with nitroglycerin and other nitrates used for angina, potentially affecting their efficacy. Patients using these medications should also consult their healthcare provider before using this cream. Furthermore, Glutathione may also interact with chemotherapeutic agents, potentially affecting their oxidative mechanisms, so patients undergoing cancer treatment should use this cream only under the guidance of their oncologist.

It is also important to consider the potential for allergic reactions or skin irritation with any topical product. Patients with a known allergy to any of the ingredients in the cream should not use it. Additionally, patients should be advised to apply a small amount of the cream to a test area of skin before widespread use to ensure they do not experience an adverse reaction.

As with any medication, it is essential to use this cream as directed by a healthcare provider and to report any unusual side effects or signs of interactions with other medications. If you have any questions or concerns about using this formulation, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream is a specialized formulation that combines two potent active ingredients, each with distinct therapeutic properties, to address various skin concerns. Glutathione, a naturally occurring antioxidant found in plants, animals, and fungi, plays a crucial role in cellular protection and metabolism. When applied topically, glutathione can help reduce oxidative stress in the skin, which is a contributing factor to aging and pigmentation. It is believed to inhibit the production of melanin, the pigment responsible for skin color, thereby lightening hyperpigmented areas and providing a more even skin tone.

Tranexamic Acid, on the other hand, is a synthetic derivative of the amino acid lysine and is known for its ability to inhibit plasminogen activation. In the context of skin care, Tranexamic Acid has been found to be effective in treating melasma and other forms of hyperpigmentation by interfering with the interaction between melanocytes and keratinocytes and reducing the inflammatory response that can lead to excess melanin production. Additionally, it has anti-inflammatory properties that can help soothe the skin and reduce redness.

The combination of Glutathione and Tranexamic Acid in a topical cream allows for a synergistic approach to treating hyperpigmentation and improving overall skin tone. The cream is formulated as a semisolid preparation, which ensures that the active ingredients are stable and can be effectively delivered to the skin. The use of a pump mechanism for dispensing the cream provides a convenient and hygienic method of application, allowing for controlled dosing and minimizing the risk of contamination. This is particularly important for maintaining the integrity of the active ingredients, which can be sensitive to air and light.

When applied to the affected areas of the skin, this cream works by penetrating the outer layers to reach deeper tissues where it can exert its effects. The formulation is designed to be absorbed gradually, ensuring a sustained release of the active ingredients over time for maximum therapeutic benefit. Patients using this cream may notice improvements in the appearance of their skin, with reduced pigmentation and a more uniform complexion. It is important to use this product as directed by a healthcare professional and to understand that results may vary based on individual skin types and conditions.

For patients and prescribers interested in using this Glutathione/Tranexamic Acid topical cream, it is essential to consider the patient's overall skin health, any existing skin conditions, and their suitability for this particular treatment. As with any topical medication, it is also important to be aware of potential side effects and interactions with other products. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this product.

Other Uses

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As compounding pharmacists at Bayview Pharmacy, we'd like to inform you of the potential alternative applications of our Glutathione 10 mg/Tranexamic Acid 100 mg/ml Topical Cream in addition to its primary indications. While this preparation is primarily designed to target pigmentation issues, melasma, and potentially for the treatment of certain types of acne scars owing to its skin-lightening and anti-inflammatory properties, it may also offer other dermatological benefits.

Glutathione, a potent antioxidant found in this formulation, plays a crucial role in detoxifying the skin and can assist in the reduction of oxidative stress, which is known to contribute to the aging process. As such, patients may experience ancillary anti-aging benefits including improved skin elasticity and the diminishment of fine lines. Furthermore, the inclusion of tranexamic acid, which has anti-inflammatory and vasoprotective properties, may make the cream beneficial for individuals with sensitive skin prone to redness or rosacea. It may help in minimizing the appearance of erythema and improve the overall skin tone.

Additionally, while research is still emerging, there is some evidence to suggest that tranexamic acid may be beneficial in the prevention of UV-induced skin damage when applied topically. When paired with sunscreen, this cream may provide a supplementary layer of defense for individuals at high risk of photodamage or with a history of actinic keratosis. However, this formulation should never replace the use of a broad-spectrum sunscreen.

It is essential to note that potential uses of this topical cream are patient-specific and results may vary. Off-label uses should be approached cautiously and always under the guidance of a healthcare professional. We, at Bayview Pharmacy, are dedicated to ensuring the highest standards of safety and efficacy in our compounded formulations. If you have any questions regarding this compounded formulation or its potential uses for your condition, please do not hesitate to reach out to us for further information and personal consultation. We are here to support both patients and prescribers in finding suitable and effective treatments tailored to individual needs.

Frequently Asked Questions

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What is the purpose of Glutathione/Tranexamic Acid Topical Cream?

Glutathione/Tranexamic Acid Topical Cream is a compounded medication designed to treat localized skin conditions, potentially reducing the appearance of dark spots, evening skin tone, and improving overall skin radiance through its antioxidant and skin-brightening activities.

How do you use Glutathione/Tranexamic Acid Topical Cream?

The cream should be applied as directed by your healthcare provider. Generally, it is applied to clean skin and rubbed in gently until fully absorbed. Its pump mechanism provides a controlled dose for each application.

Can Glutathione/Tranexamic Acid Topical Cream be used on sensitive skin?

While it is formulated for tolerance, skin sensitivity varies. It's recommended to test a small area before widespread use. If irritation or adverse reactions occur, discontinue use and consult your healthcare provider.

Is this cream suitable for all skin types?

The cream is designed to be suitable for most skin types. However, it is always advisable to discuss with your healthcare provider to ensure it is appropriate for your specific skin condition and type.

How should Glutathione/Tranexamic Acid Topical Cream be stored?

Store the cream at room temperature, away from direct sunlight and heat. Ensure the pump is locked or closed to prevent the product from drying out.

Can Glutathione/Tranexamic Acid Topical Cream be used with makeup?

Generally, the cream can be used under makeup. Allow it to be fully absorbed before applying makeup for best results. It's important, however, to wait for a few minutes to ensure proper absorption.

How frequently should Glutathione/Tranexamic Acid Topical Cream be applied?

Follow your healthcare provider's instructions regarding frequency of application, as it may vary based on your individual skin care needs and the specific skin condition treated.

Can this cream be used during the day?

Yes, Glutathione/Tranexamic Acid Topical Cream can be used during the day, but you should apply a broad-spectrum sunscreen as the cream may make your skin more sensitive to the sun.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for the missed dose.

Are there any known side effects of using Glutathione/Tranexamic Acid Topical Cream?

Some potential side effects may include skin irritation, redness, or reaction at the site of application. If you experience any severe or concerning symptoms, immediately contact your healthcare provider.

Is a prescription required for Glutathione/Tranexamic Acid Topical Cream?

Yes, Glutathione/Tranexamic Acid Topical Cream is a compounded medication and requires a prescription from a healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.