This formulation is a topical cream containing Flurbiprofen 100 mg/g and Lidocaine 50 mg/g, designed for application on the skin using a convenient pump mechanism. The semisolid preparation allows for controlled and localized delivery of active ingredients directly to the affected area. Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and pain by inhibiting prostaglandin synthesis. Lidocaine is a local anesthetic that provides rapid pain relief by blocking nerve signals in the skin.

When combined in a topical cream, Flurbiprofen and Lidocaine work synergistically to alleviate pain and reduce inflammation associated with various musculoskeletal conditions. This formulation is particularly useful for managing localized pain due to arthritis, tendonitis, bursitis, sprains, strains, and other soft tissue injuries. The targeted application minimizes systemic absorption, potentially reducing the risk of systemic side effects commonly associated with oral NSAIDs.

For patients, this cream offers a convenient and effective option for managing pain and discomfort without the need for oral medication. The pump mechanism ensures accurate dosing and reduces the potential for mess or wastage. To use the cream, apply the prescribed amount to the affected area and gently massage until absorbed. Wash hands thoroughly after application to avoid accidental contact with eyes or mucous membranes.

Prescribers may find this formulation beneficial for patients who cannot tolerate oral NSAIDs or who require additional localized pain control. The combination of an anti-inflammatory agent with a local anesthetic addresses both the underlying inflammation and immediate pain sensations. It is important to assess the patient's overall medication profile to avoid potential interactions and to consider any contraindications such as hypersensitivity to NSAIDs or local anesthetics.

Common side effects may include skin irritation at the application site, such as redness, itching, or rash. Patients should discontinue use and consult their healthcare provider if they experience severe irritation or signs of an allergic reaction. As with all medications, it is important to use this cream exactly as prescribed and to report any concerning symptoms to a healthcare professional promptly.

If you have any questions about this formulation or its use, please reach out to us.

Flurbiprofen 100 mg/g and Lidocaine 50 mg/g topical cream is a compounded formulation designed for localized treatment of pain and inflammation. Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, thereby reducing inflammation and pain. Lidocaine is a local anesthetic that provides pain relief by blocking nerve signals in the body. When combined in a topical cream, these active ingredients offer a synergistic effect for the management of localized pain conditions.

Patients and prescribers should be aware of potential drug interactions when using this topical formulation. Although the systemic absorption of flurbiprofen and lidocaine from topical application is generally lower compared to oral or injectable forms, interactions can still occur, especially with prolonged use or application over large surface areas. It is important to consider the patient's overall medication regimen to avoid adverse effects.

Flurbiprofen, as an NSAID, may interact with other medications that affect bleeding risk, such as anticoagulants (e.g., warfarin), antiplatelet agents (e.g., aspirin, clopidogrel), and other NSAIDs. Concurrent use of these medications can increase the risk of gastrointestinal bleeding and should be monitored closely. Additionally, flurbiprofen may reduce the efficacy of antihypertensive drugs, including ACE inhibitors, angiotensin II receptor blockers, and diuretics, potentially leading to elevated blood pressure.

Lidocaine, when absorbed systemically, can interact with antiarrhythmic drugs, such as amiodarone and mexiletine, potentially leading to additive cardiac effects. Caution is advised when using this topical cream in patients receiving these medications. Furthermore, lidocaine may enhance the effects of other local anesthetics and should be used with caution in patients receiving multiple local anesthetic agents.

Patients with pre-existing conditions such as liver or kidney impairment should use this formulation with caution, as these conditions can affect the metabolism and excretion of both flurbiprofen and lidocaine, potentially leading to increased systemic exposure and risk of toxicity. It is crucial to assess the patient's medical history and current medications to ensure safe use of this topical cream.

If you have any questions or concerns about potential drug interactions or the use of this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The Flurbiprofen 100 mg/g and Lidocaine 50 mg/g topical cream is a compounded semisolid preparation designed for targeted application on the skin, utilizing a pump mechanism for precise and controlled dosing. This formulation is specifically crafted to deliver the active ingredients directly to the site of pain or inflammation, providing localized treatment and minimizing systemic exposure. The combination of Flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), and Lidocaine, a local anesthetic, offers a dual-action approach to managing pain and inflammation.

Flurbiprofen works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins. Prostaglandins are lipid compounds that play a key role in the inflammatory process, contributing to pain, swelling, and redness. By reducing the production of these compounds, Flurbiprofen effectively decreases inflammation and alleviates pain at the site of application. This makes it particularly useful for conditions characterized by localized inflammation, such as arthritis, tendonitis, or musculoskeletal injuries.

Lidocaine, on the other hand, acts as a local anesthetic by blocking sodium channels in the neuronal cell membrane. This action prevents the initiation and conduction of nerve impulses, leading to a temporary loss of sensation in the treated area. By numbing the skin and underlying tissues, Lidocaine provides immediate pain relief, which can be especially beneficial for acute pain episodes or during the initial phase of treatment when inflammation is most pronounced.

The pump mechanism of this topical cream ensures that patients and prescribers can easily control the amount of medication applied, promoting consistent dosing and reducing the risk of over-application. This feature enhances patient compliance and optimizes therapeutic outcomes by ensuring that the active ingredients are delivered in the correct concentration to the affected area.

For patients, this formulation offers a convenient and effective option for managing localized pain and inflammation without the systemic side effects often associated with oral NSAIDs or anesthetics. For prescribers, it provides a customizable treatment option that can be tailored to the specific needs of each patient, allowing for adjustments in dosing or frequency based on the severity of symptoms and individual response to treatment.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to make informed decisions about your treatment options.

Flurbiprofen 100 mg/g and Lidocaine 50 mg/g topical cream, dispensed in a semisolid preparation with a pump mechanism, offers a versatile option for localized treatment or absorption of active ingredients through the skin. While primarily used for managing pain and inflammation associated with musculoskeletal conditions, this formulation may have other potential applications that could benefit both patients and prescribers seeking alternative therapeutic options. The combination of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), and lidocaine, a local anesthetic, provides a dual-action approach that can be particularly useful in managing localized pain and inflammation.

Beyond its primary indications, this topical cream may be considered for off-label uses in conditions where localized pain relief and anti-inflammatory effects are desired. For instance, it could be beneficial in managing pain associated with minor injuries such as sprains, strains, or contusions, where reducing inflammation and providing immediate pain relief can aid in faster recovery. Additionally, patients with localized neuropathic pain conditions, such as post-herpetic neuralgia or diabetic neuropathy, might find relief from the numbing effect of lidocaine combined with the anti-inflammatory properties of flurbiprofen.

In dermatological settings, this formulation might be explored for its potential to alleviate discomfort from inflammatory skin conditions, such as localized psoriasis or eczema flare-ups, where inflammation and pain are prominent symptoms. Furthermore, it could be used in post-surgical settings to manage localized pain and inflammation, potentially reducing the need for systemic pain medications and their associated side effects. The pump mechanism ensures precise dosing and minimizes wastage, making it a convenient option for patients who require consistent and controlled application.

It is important for prescribers to consider the patient's overall health status, potential drug interactions, and specific needs when contemplating the use of this formulation for off-label purposes. Patients should be advised to apply the cream as directed and report any adverse reactions or lack of efficacy to their healthcare provider. As with any medication, the benefits and risks should be carefully weighed, and usage should be tailored to the individual patient's condition and response to treatment. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy.