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Formulas

Fluoxetine HCl 22.4 mg/5 mL Oral Liquid

Our Fluoxetine HCl 22.4 mg/5 mL Oral Liquid is a specially crafted medication designed for oral use, ensuring a precise and consistent dose of fluoxetine hydrochloride in each administration. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing pills, including children and the elderly. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed to treat a variety of disease states such as major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, and bulimia nervosa. By providing this medication in a liquid form, we aim to facilitate adherence to treatment regimens and improve patient outcomes in managing these conditions.

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Fluoxetine Hydrochloride
Oral Liquid
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Formula Information

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Fluoxetine HCl 22.4 mg/5 mL Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This oral liquid formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those with conditions that impair their ability to ingest solid dosage forms. The liquid form allows for flexible dosing, which can be adjusted according to the specific needs of the patient.

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly used in the treatment of major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. By increasing the levels of serotonin in the brain, fluoxetine can help to improve mood, sleep, appetite, and energy level, while also decreasing fear, anxiety, unwanted thoughts, and the number of panic attacks. It is also effective in reducing the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living.

The 22.4 mg/5 mL concentration allows for accurate dosing, which is critical for achieving the desired therapeutic effect while minimizing potential side effects. The liquid formulation should be measured with a provided dosing device to ensure the correct dose is administered. It is important to shake the bottle well before each use to ensure the medication is evenly distributed. Patients should be advised to follow their prescriber's instructions regarding dosage and duration of therapy, as abrupt cessation or changes in dosage without consultation can lead to adverse effects or a relapse of symptoms.

As with all medications, there may be potential side effects, and patients should be made aware of these. Common side effects of fluoxetine can include nausea, drowsiness, dizziness, anxiety, trouble sleeping, loss of appetite, tiredness, sweating, or yawning. If any of these effects persist or worsen, patients should contact their healthcare provider. More serious side effects should be reported immediately, and it is important for patients to be monitored for any worsening of their condition or unusual behavior changes, especially at the start of treatment or when doses are adjusted.

For prescribers considering this formulation for their patients, it is important to assess the patient's complete medical history, including any other medications they are taking to avoid potential drug interactions. Fluoxetine can interact with other medications, and it is particularly important to avoid taking MAO inhibitors or other SSRIs within 14 days before or after treatment with fluoxetine. Prescribers should also be aware of the potential for serotonin syndrome, a potentially life-threatening condition, when fluoxetine is combined with other serotonergic drugs.

At Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the unique needs of our patients. If you have any questions about this formulation or its appropriateness for your patient, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists is here to support you and provide the information you need to ensure the best possible outcomes for your patients.

Drug Interactions

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Fluoxetine HCl, the active ingredient in this oral liquid formulation, is a selective serotonin reuptake inhibitor (SSRI) commonly used to treat a variety of psychiatric conditions including depression, obsessive-compulsive disorder, panic disorder, and certain eating disorders. As with any medication, fluoxetine can interact with a wide range of other drugs, which can affect the efficacy of the treatment and may lead to adverse effects.

One of the most significant interactions is with monoamine oxidase inhibitors (MAOIs). Combining fluoxetine with MAOIs can lead to a potentially life-threatening condition called serotonin syndrome. Symptoms of serotonin syndrome may include confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Therefore, fluoxetine should not be used in combination with an MAOI, or within 14 days of discontinuing treatment with an MAOI. At least 5 weeks should be allowed after stopping fluoxetine before starting an MAOI.

Other important drug interactions include, but are not limited to, other central nervous system (CNS) acting drugs such as benzodiazepines, antipsychotics, and other antidepressants, which can increase the risk of CNS side effects like sedation and cognitive impairment. The risk of bleeding may be increased when fluoxetine is combined with anticoagulants like warfarin, nonsteroidal anti-inflammatory drugs (NSAIDs), or other drugs that affect coagulation. Fluoxetine can also affect the blood levels of other medications by inhibiting certain liver enzymes (particularly CYP2D6), which can lead to increased concentrations and potential toxicity of drugs metabolized by these enzymes, such as certain antipsychotics, beta-blockers, and Type 1C antiarrhythmics like propafenone and flecainide.

Additionally, fluoxetine may interact with drugs that prolong the QT interval, a measure of heart rhythm. When combined with other QT-prolonging drugs or in patients with a history of QT prolongation, this can increase the risk of developing an abnormal heart rhythm known as torsades de pointes, which can be life-threatening. Drugs that can cause electrolyte imbalances (such as diuretics) may also increase this risk when taken with fluoxetine.

It is also important to consider that fluoxetine can interact with over-the-counter medications and herbal supplements. For example, combining fluoxetine with St. John's Wort can increase the risk of serotonin syndrome, and taking it with aspirin or other NSAIDs can increase the risk of gastrointestinal bleeding.

Patients should be advised to inform their healthcare providers of all the medications they are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Healthcare providers should carefully consider the potential interactions before prescribing fluoxetine and monitor patients for any signs of adverse effects or unusual changes in behavior, especially during the initiation and after changes in dosage. If you have any questions or concerns regarding this fluoxetine oral liquid formulation or its potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Fluoxetine HCl 22.4 mg/5 mL Oral Liquid is a specially designed medication that is administered orally. This liquid formulation is particularly beneficial for patients who have difficulty swallowing pills or capsules, such as children and the elderly. The liquid form allows for flexible dosing, which can be precisely measured to ensure the patient receives the exact amount of medication required for their treatment. The active ingredient, Fluoxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) that works by increasing the levels of serotonin in the brain, a neurotransmitter associated with mood regulation.

Fluoxetine is primarily used to treat major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. It helps alleviate symptoms such as feelings of sadness, anxiety, and compulsive behaviors by restoring the balance of serotonin in the brain. The efficacy of Fluoxetine in treating these conditions has been well-documented through extensive clinical research. It is important to note that the onset of action for Fluoxetine can take several weeks, and it should be taken consistently as prescribed by a healthcare provider to achieve the best results.

When using the Fluoxetine HCl 22.4 mg/5 mL Oral Liquid, it is crucial to shake the bottle well before each use to ensure the medication is evenly distributed throughout the solution. Patients should use the measuring device provided by the pharmacy to measure their dose accurately. It is also important to store the medication at room temperature and keep it away from light and moisture to maintain its effectiveness. As with any medication, there may be potential side effects, and patients should be monitored for any adverse reactions or changes in behavior, especially when initiating treatment or adjusting the dose.

For prescribers considering this formulation for their patients, it is essential to assess the patient's medical history, current medications, and potential drug interactions. Fluoxetine can interact with a variety of medications, and careful consideration is needed when prescribing it to patients with certain medical conditions. Prescribers should provide patients with comprehensive instructions on how to take the medication and discuss the importance of adherence to the prescribed regimen.

If you have any questions or require further information about the Fluoxetine HCl 22.4 mg/5 mL Oral Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing support and guidance to ensure the safe and effective use of this medication.

Other Uses

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The Fluoxetine HCl 22.4 mg/5 mL Oral Liquid is formulated primarily to treat major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder, but it may have additional applications. Aside from these FDA-approved indications, fluoxetine has been used off-label for the treatment of various other conditions. These include, but are not limited to, anxiety disorders, such as social anxiety disorder and generalized anxiety disorder, which often co-occur with depression, as well as specific phobias. Some studies have also suggested potential effectiveness in treating post-traumatic stress disorder (PTSD).

Furthermore, fluoxetine can be used in the management of symptoms of neurological disorders, for instance, neurogenic pain, and it may serve as an adjunct in the treatment of obesity by helping to reduce binge-eating behaviors. Researchers have explored its utility in addressing alcohol dependence, with some suggesting it may aid in reducing craving. In pediatric patients, fluoxetine has shown some efficacy in the treatment of autism spectrum disorders, particularly in addressing repetitive behaviors and improving social interaction. It should be noted that the off-label use of fluoxetine should be undertaken with caution and under the supervision of a healthcare provider.

Lastly, the unique liquid formulation of Fluoxetine HCl 22.4 mg/5 mL is particularly beneficial for patients who experience difficulty swallowing pills, which can include individuals with esophageal disorders, dysphagia, or those who require enteral feeding tubes. Additionally, the availability of a liquid dosage form allows for flexible dosing, which is particularly advantageous for pediatric and geriatric patients where dosing often requires adjustments based on weight or sensitivity to medication. It is also a preferable option for those who require very precise dosing or incremental dose adjustments, which are more challenging to achieve with solid dosage forms.

It is crucial for prescribers to consider the full clinical profile of their patients before prescribing fluoxetine in any form, including potential drug-drug interactions, contraindications, and the specific symptomatology being addressed. Patients or prescribers with questions or who are considering this formulation for other uses are encouraged to reach out to us at Bayview Pharmacy for more personalized information and guidance on the safe and effective use of Fluoxetine HCl 22.4 mg/5 mL Oral Liquid.

Frequently Asked Questions

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What is Fluoxetine HCl 22.4 mg/5 mL Oral Liquid?

Fluoxetine HCl 22.4 mg/5 mL Oral Liquid is a specifically formulated medication that is intended for oral administration. It contains Fluoxetine Hydrochloride in a liquid form to provide a convenient and easily ingested dosage for accurate delivery of the antidepressant medication, especially beneficial for individuals who find swallowing solid dosage forms challenging.

How should I take Fluoxetine HCl Oral Liquid?

The liquid should be measured with the provided dosing syringe or cup to ensure the correct dose is administered. It can be taken with or without food, but it should be taken at the same time each day to maintain an even level of medication in the body.

Who might benefit from Fluoxetine HCl Oral Liquid?

It is often prescribed for pediatric and geriatric patients, as well as others who have difficulty swallowing pills, such as individuals with dysphagia or those who require precise dosing that can be easier to achieve with a liquid formulation.

Can I mix Fluoxetine HCl Oral Liquid with other liquids?

It is generally acceptable to mix the medication with water or another suitable beverage to make it easier to take. However, it's important to consult with a healthcare provider or pharmacist before mixing it with other liquids to ensure compatibility and effectiveness.

What are the potential side effects of Fluoxetine HCl Oral Liquid?

Common side effects may include nausea, drowsiness, dizziness, anxiety, trouble sleeping, loss of appetite, or sweating. Severe side effects should be reported to a doctor immediately and might include irregular heartbeat, severe dizziness, fainting, or muscle weakness.

Can I stop taking Fluoxetine HCl Oral Liquid abruptly?

Fluoxetine HCl Oral Liquid should not be stopped abruptly due to the risk of withdrawal symptoms. It is important to consult with your healthcare provider before making any changes to your medication regimen.

How should I store Fluoxetine HCl Oral Liquid?

Store this medication at room temperature away from light and moisture, and keep it out of reach of children and pets. Do not freeze the liquid, and after opening, refer to the product label or consult a pharmacist for shelf life information.

What if I miss a dose of Fluoxetine HCl Oral Liquid?

If a dose is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Are there any interactions with other medications when taking Fluoxetine HCl Oral Liquid?

Fluoxetine can interact with a number of other medications, including MAO inhibitors, other antidepressants, blood thinners, and certain pain medications. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.

Is Fluoxetine HCl Oral Liquid safe for use during pregnancy or while breastfeeding?

Prior to using this medication during pregnancy or while breastfeeding, it is crucial to discuss the potential risks and benefits with your healthcare provider, as the medication can pass into breast milk and may have undesirable effects on a nursing infant.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.