Check out our most popular compounded medications! Get Started
The Fluorouracil 5%/Salicylic acid 12% Topical Liquid is a compounded medication specifically designed for direct application to the skin. This formulation combines the antineoplastic properties of Fluorouracil with the keratolytic effects of Salicylic acid. The liquid dosage form ensures precise application to affected areas, minimizing systemic absorption and maximizing localized therapeutic benefits.
This topical solution is primarily indicated for the treatment of actinic keratosis, a precancerous skin condition caused by prolonged exposure to ultraviolet (UV) radiation. It is also used in the management of superficial basal cell carcinomas, offering a non-invasive treatment option for patients. By promoting the shedding of the outer layer of skin, Salicylic acid enhances the penetration of Fluorouracil.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Fluorouracil 5%/Salicylic acid 12% Topical Liquid is a compounded medication specifically designed for the treatment of various skin conditions. Fluorouracil is a topical antineoplastic agent, primarily used for its ability to inhibit the growth of abnormal cells. It works by interfering with DNA synthesis, thus preventing the proliferation of rapidly dividing cells. Salicylic acid, on the other hand, is a keratolytic agent that facilitates the shedding of the outer layer of skin. It is commonly used for its exfoliating properties to treat conditions like psoriasis, acne, and warts. The combination of these two agents in a 5% and 12% concentration respectively, enhances the efficacy of the treatment by allowing fluorouracil to penetrate deeper into the skin after salicylic acid has exfoliated the dead skin cells.
This topical liquid formulation is particularly beneficial for patients requiring localized therapy with minimal systemic absorption. It is applied directly to the affected area, which allows for high local concentrations of the medication. The liquid form is easy to apply and can be particularly useful for treating areas that are difficult to cover with more solid dosage forms.
Patients should be advised that the use of this medication may lead to local skin reactions, including redness, irritation, and photosensitivity. It is important to follow the application instructions provided by the healthcare provider to minimize adverse effects. Prescribers should consider the patient's overall medical history, including any known hypersensitivities to fluorouracil or salicylic acid, before recommending this treatment. Regular monitoring of the treatment area is recommended to assess the response to therapy and to manage any potential complications.
For optimal results, the use of this compounded medication should be part of a comprehensive treatment plan that may include other modalities such as protective clothing and sunscreen to prevent further sun damage. Patients and prescribers interested in using this formulation are encouraged to reach out to us at Bayview Pharmacy for more information, personalized advice, and to address any questions regarding the preparation, application, or expected outcomes of this treatment.
The combination of fluorouracil and salicylic acid in a topical liquid formulation is primarily used for the treatment of skin conditions such as actinic or solar keratosis and superficial basal cell carcinomas. Fluorouracil is a topical chemotherapy agent that works by interfering with DNA synthesis, thereby inhibiting the growth of abnormal skin cells. Salicylic acid acts as a keratolytic, helping to soften and remove scales, crusts, and dead skin cells, which can enhance the penetration and effectiveness of fluorouracil.
When using this combination topical liquid, it is important to consider potential drug interactions. Fluorouracil should be used with caution in patients who are also taking other medications that can affect the bone marrow or have immunosuppressive effects, such as other chemotherapy agents, because the combination may increase the risk of hematological toxicity or other adverse effects. Although systemic absorption of fluorouracil through the skin is minimal, caution is still advised.
Salicylic acid, while also minimally absorbed through the skin, may interact with other topical treatments that affect skin turnover or that are potentially irritating. Concurrent use of other topical acne medications, peeling agents, or products containing alcohol, astringents, spices, lime, or other strong drying agents may result in additive irritation and dryness of the skin. Patients should avoid using other topical medications on the treated area unless directed by a healthcare provider.
Additionally, caution should be exercised when using this formulation in patients who are taking oral anticoagulants, such as warfarin, or other drugs that affect platelet function, such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs). Although the risk of systemic absorption and subsequent interaction is low, salicylic acid can theoretically increase the risk of bleeding when absorbed in significant amounts.
Patients should also be advised to protect the treated areas from sunlight and ultraviolet light, as both fluorouracil and salicylic acid can make the skin more sensitive to sunlight, potentially leading to a more intense reaction, such as sunburn.
It is essential for patients to inform their healthcare providers of all medications, supplements, and herbal products they are currently using before starting treatment with this topical liquid formulation. This will help to identify any potential interactions and allow for appropriate monitoring or adjustments to therapy. If you have any questions or concerns about using this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.
The Fluorouracil 5%/Salicylic acid 12% Topical Liquid is a specially compounded medication that combines two active ingredients, fluorouracil and salicylic acid, in a liquid formulation for direct application to the skin. This medication is primarily used for the treatment of various skin conditions, including actinic or solar keratosis and superficial basal cell carcinomas, which are precancerous and cancerous skin lesions respectively. The liquid form allows for precise application to affected areas, minimizing exposure to healthy skin.
Fluorouracil is a topical antineoplastic agent, which means it works by inhibiting the growth and proliferation of abnormal cells. It is a type of chemotherapy drug that is used in a topical form to treat skin lesions. When applied to the skin, fluorouracil is absorbed by the abnormal cells and interferes with DNA synthesis and cell replication. This causes the death of rapidly dividing cells, particularly cancerous or precancerous cells, leading to a reduction in the size and number of lesions.
Salicylic acid, on the other hand, is a keratolytic agent. It works by softening the keratin in the skin, which is a protein that forms part of the skin structure. By softening keratin, salicylic acid helps to loosen and shed the outer layer of skin cells. This action not only aids in the removal of scales and crusts associated with skin lesions but also enhances the penetration of fluorouracil into the skin, increasing its efficacy. Additionally, salicylic acid has mild anti-inflammatory properties that can help reduce swelling and redness.
The combination of fluorouracil and salicylic acid in a single formulation provides a synergistic effect, where salicylic acid enhances the therapeutic action of fluorouracil. The concentration of 5% fluorouracil and 12% salicylic acid has been specifically chosen to balance efficacy with tolerability, ensuring that the medication is strong enough to treat the lesions while minimizing potential irritation to the skin.
Patients using this formulation should apply it as directed by their healthcare provider, typically to the affected area once or twice daily. It is important to follow the application instructions carefully to avoid exposure to healthy skin and mucous membranes. The duration of treatment may vary depending on the response and the condition being treated. Patients should be aware that the treated area may become red, sore, or inflamed during therapy, which is a common reaction as the abnormal cells are destroyed.
Prescribers considering this formulation for their patients should be aware of the potential side effects and the importance of monitoring the treatment progress. They should also counsel patients on proper application techniques and the importance of adhering to the prescribed treatment regimen. As with any medication, it is crucial to consider the patient's overall health status, including any other skin conditions or sensitivities, before prescribing this topical liquid.
If you have any questions or require further information about the Fluorouracil 5%/Salicylic acid 12% Topical Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance needed to ensure the safe and appropriate use of this medication.
This compounded medication is used primarily for the treatment of various skin conditions, including actinic or solar keratoses and superficial basal cell carcinomas. Its two active ingredients, fluorouracil and salicylic acid, work together to inhibit abnormal cell growth and remove excess skin cells.
Apply the liquid directly to the affected area of the skin with a non-metal applicator or suitable glove. Ensure the skin is clean and dry before application. Only use the amount prescribed by your healthcare provider and follow their specific instructions regarding the frequency and duration of treatment.
Fluorouracil 5%/Salicylic acid 12% Topical Liquid is intended for external use only and should typically be applied only to the specific areas of the skin as directed by your healthcare provider. Avoid using it on sensitive areas such as around the eyes, and do not ingest or use it internally.
If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and return to your regular application schedule. Do not apply extra medication to make up for a missed dose.
Yes, as with any medication, there may be side effects. Common ones for this topical liquid include redness, irritation, peeling, and sensitivity at the application site. If you experience severe discomfort or signs of an allergic reaction, contact your healthcare provider immediately.
Your healthcare provider may instruct you to cover the treated area with a permeable dressing. However, occlusive dressings that do not breathe should generally be avoided unless specifically recommended by your healthcare provider.
It is best to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, such as hats and long sleeves, when using this medication. Fluorouracil may increase your skin's sensitivity to sunlight, which could worsen the condition being treated.
Store the medication at room temperature, away from light and moisture. Keep it out of reach of children and pets and do not freeze the medication unless required by the label or your healthcare provider.
Typically, you should avoid using other skin products including cosmetics, lotions, or creams over the treated area unless your healthcare provider tells you otherwise. Doing so can affect the medication's efficacy or exacerbate side effects.
The safety of Fluorouracil 5%/Salicylic acid 12% Topical Liquid during pregnancy or breastfeeding is not well-established. It is crucial to consult with your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or are breastfeeding.
Response times can vary based on the individual and the condition being treated. It may take several weeks to see noticeable improvements. Your healthcare provider will be able to give you more specific guidance on what to expect in terms of results.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
