Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Fluconazole 2% Topical Nail Liquid

Fluconazole 2% Topical Nail Liquid is a specially crafted formulation intended for direct application to the nails. This antifungal solution is designed to combat nail fungal infections, a common condition known as onychomycosis, which can lead to nail brittleness, discoloration, and distortion. By delivering fluconazole directly to the affected area, this liquid formulation aids in the eradication of fungal pathogens, fostering the restoration of healthy nail tissue and enhancing the overall aesthetics of the nails.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Fluconazole
Nail Solution
6564f7db7b8d7468074ac0c1
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

Fluconazole 2% Topical Nail Liquid is a specially compounded formulation designed to treat a variety of nail conditions, including fungal infections, which are often characterized by nail brittleness, discoloration, and thickening. Fluconazole is an antifungal agent that works by inhibiting the growth of a wide range of fungi by interfering with the synthesis of the fungal cell membrane. This targeted approach ensures that the active ingredient is delivered directly to the site of infection, maximizing efficacy and reducing systemic absorption.

The liquid dosage form is particularly suitable for nail application as it allows for easy application and penetration into the nail bed and matrix. This is essential for treating onychomycosis, a common nail fungus, as the infection resides within the nail plate and the nail bed. The formulation is designed to enhance the permeation of fluconazole through the dense keratin structure of the nail, thereby providing a conducive environment for the medication to reach the site of infection and act effectively.

Patients using Fluconazole 2% Topical Nail Liquid should apply the medication as directed by their healthcare provider, typically once or twice daily. Consistent application over the prescribed treatment period is crucial for the successful resolution of the fungal infection. It is important to continue using the medication for the full duration of the prescribed course, even if symptoms appear to improve, to prevent recurrence of the infection.

Prescribers should consider this formulation for patients who require localized treatment for nail fungal infections without the potential side effects associated with systemic antifungal therapy. Additionally, this formulation may be beneficial for patients who have not responded to over-the-counter treatments or for those who have contraindications to oral antifungal medications.

For optimal results, the affected nails should be kept clean and dry, and patients should be advised on proper nail hygiene to prevent the spread of infection. It is also important to monitor the progress of the treatment and the condition of the nails, adjusting the treatment regimen as necessary based on the patient's response.

If you have any questions or require further information about Fluconazole 2% Topical Nail Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and prescribers to ensure the safe and effective use of this specialized medication.

Drug Interactions

A small arrow pointing down

Fluconazole is an antifungal agent that works by inhibiting the growth of various types of fungi by disrupting the production of the fungal cell membrane. When formulated as a 2% topical nail liquid, fluconazole is used to treat fungal infections of the nails, such as onychomycosis. It can also help with conditions that cause brittleness or discoloration of the nails by eliminating the underlying fungal infection and allowing for the healthy regrowth of the nail. The topical application ensures that the drug is delivered directly to the affected area, minimizing systemic absorption and reducing the risk of systemic side effects.

While the systemic absorption of fluconazole in a topical nail liquid formulation is expected to be minimal, it is still important to consider potential drug interactions, especially if the patient is taking other medications that could interact with fluconazole. For instance, fluconazole is a potent inhibitor of the cytochrome P450 enzyme CYP2C19, CYP2C9, and CYP3A4. Drugs that are substrates of these enzymes may have increased plasma concentrations when used concomitantly with fluconazole, potentially leading to adverse effects or toxicity. Examples include certain anticoagulants like warfarin, benzodiazepines, calcium channel blockers, and some statins. Patients should be advised to inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements.

Additionally, fluconazole can interact with drugs that prolong the QT interval, such as certain antiarrhythmics, antipsychotics, and antibiotics. Although the risk is lower with topical administration, caution is still advised, especially in patients with additional risk factors for QT prolongation. Patients with known cardiac conditions or those on medications affecting cardiac conduction should be monitored closely if fluconazole treatment is initiated.

Alcohol consumption should be minimized or avoided during treatment with fluconazole, as it may increase the risk of liver toxicity. Patients with pre-existing liver conditions should use fluconazole with caution and under close supervision by a healthcare provider. Regular monitoring of liver function tests may be recommended in these cases.

It is also important to note that while the topical route of administration reduces systemic exposure, there is still a possibility of local skin reactions, such as redness, itching, or irritation at the site of application. These reactions are usually mild and transient. However, if severe skin reactions occur, treatment should be re-evaluated, and appropriate measures should be taken.

For any questions or concerns regarding the use of Fluconazole 2% Topical Nail Liquid, or to report any adverse reactions or interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

How Does it Work

A small arrow pointing down

Fluconazole is an antifungal medication that belongs to a class of drugs known as triazole antifungals. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. Without ergosterol, the cell membrane becomes weak and permeable, leading to the leakage of cellular contents and ultimately the death of the fungal cell. This mechanism of action makes fluconazole effective in treating fungal infections of the nails, also known as onychomycosis.

When formulated as a 2% topical nail liquid, fluconazole is specifically designed to be applied directly to the affected nails. This allows for a high concentration of the drug to be delivered to the site of infection, which can enhance the effectiveness of the treatment. The topical application helps to minimize systemic absorption, reducing the potential for side effects that may occur with oral antifungal medications. This is particularly beneficial for patients who may not tolerate oral antifungals or have contraindications to systemic therapy.

The liquid formulation is also advantageous as it can penetrate the hard keratin structure of the nails more effectively than creams or ointments. This penetration is crucial for reaching the site of the fungal infection, which is often located deep within the nail bed or under the nail plate. The liquid vehicle may also contain agents that enhance the permeation of fluconazole into the nail, further improving the efficacy of the treatment.

By applying the fluconazole 2% topical nail liquid as directed, patients can expect a gradual improvement in the appearance and integrity of their nails. The treatment works to eradicate the fungal infection, leading to a reduction in nail brittleness, discoloration, and other associated symptoms. It is important for patients to adhere to the prescribed treatment regimen and to continue using the medication for the full duration recommended by their healthcare provider, as fungal nail infections can be slow to resolve.

For prescribers considering this formulation for their patients, it is important to note that while fluconazole is effective against many common fungal pathogens, some species may be resistant. Therefore, it may be beneficial to perform a nail culture or other diagnostic tests to identify the causative organism before initiating treatment. Additionally, prescribers should consider the patient's medical history, including any potential drug interactions or contraindications.

If you have any questions about the fluconazole 2% topical nail liquid or its use in treating nail conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

Other Uses

A small arrow pointing down

Fluconazole 2% Topical Nail Liquid is primarily indicated for the treatment of fungal nail infections, which can manifest as onychomycosis. This condition is known for causing thickening, discoloration, and separation of the nail from the nail bed. While our expert formulation is specially designed to combat fungal pathogens affecting the nails, providing relief and restoring the healthy appearance of the nails, the antifungal properties of Fluconazole may have additional benefits.

Aside from its primary indication, this formulation could also play a supportive role in managing yeast and Candida infections of the nails, which are less common but can be similarly distressing for patients. It is also worth considering for individuals who, due to certain occupations or lifestyles, are at increased risk of developing recurrent fungal nail infections. In such cases, periodic application of the Fluconazole 2% Topical Nail Liquid might serve as a preventive measure. Additionally, due to its antifungal properties, patients with secondary bacterial infections might experience some benefits, although this formulation is not specifically intended to be antibacterial. It’s important to note, however, that this medication has not been approved for these secondary uses, and its efficacy in such scenarios may not have been extensively researched or verified.

Patients or prescribers interested in exploring off-label or secondary uses of the Fluconazole 2% Topical Nail Liquid should consult with our team at Bayview Pharmacy. We can provide personalized advice based on the latest research and our professional experience. Adjustments in the treatment regimen may be necessary depending upon the specific condition being addressed, and close monitoring for efficacy and safety is always recommended. Our knowledgeable team is available to address queries regarding this formulation and to ensure its use is optimized for each patient's unique needs. Please feel free to reach out to us with any questions regarding this treatment option.

Frequently Asked Questions

A small arrow pointing down

What is Fluconazole 2% Topical Nail Liquid used for?

Fluconazole 2% Topical Nail Liquid is used to treat fungal infections of the nails, also known as onychomycosis. It may also help with other nail conditions, such as brittleness or discoloration, by delivering antifungal medication directly to the affected area to promote healthy nail growth and improve the overall appearance of the nails.

How do I apply Fluconazole 2% Topical Nail Liquid?

To apply the liquid, clean and dry the affected nails thoroughly. Then, using a brush or a dropper, apply a thin layer of the medication over the entire surface of the nail, including the underside of the nail tip, once or twice daily as directed by your healthcare provider. Ensure the liquid dries completely before putting on socks or shoes.

Can Fluconazole 2% Topical Nail Liquid be used on fingernails as well as toenails?

Yes, Fluconazole 2% Topical Nail Liquid can be used on both fingernails and toenails. However, always check with your healthcare provider for specific recommendations and instructions for use on different types of nails.

How long does it take to see results with Fluconazole 2% Topical Nail Liquid?

The time it takes to see results can vary depending on the severity of the nail fungus and individual response to treatment. Some patients may see improvement within a few weeks, while others may need several months of consistent use to notice significant changes. Continue to use the medication as directed until your healthcare provider advises that it is no longer necessary.

Should I use Fluconazole 2% Topical Nail Liquid if I am pregnant or breastfeeding?

Consult your healthcare provider before using Fluconazole 2% Topical Nail Liquid if you are pregnant, plan to become pregnant, or are breastfeeding. Your doctor will help you weigh the benefits and potential risks to determine whether it's safe for you to use the medication.

Can I use nail polish or other nail products while using this medication?

It's generally not recommended to use nail polish or other cosmetic nail products on the treated nails as they might prevent the medication from being absorbed effectively. Check with your healthcare provider for specific advice related to your treatment plan.

What should I do if I miss a dose of Fluconazole 2% Topical Nail Liquid?

If you miss a dose of Fluconazole 2% Topical Nail Liquid, apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the doses to catch up.

Can I use Fluconazole 2% Topical Nail Liquid if I am allergic to azole antifungals?

If you have a known allergy to azole antifungals, including Fluconazole, you should not use this medication. Tell your healthcare provider about any allergies you have so they can provide you with a suitable alternative.

Are there any side effects associated with Fluconazole 2% Topical Nail Liquid?

Side effects are generally rare with topical applications, but some individuals may experience mild local reactions such as skin irritation, itching, redness, or swelling around the nail area. If you experience any severe side effects or symptoms of an allergic reaction, contact your healthcare provider immediately.

How should I store Fluconazole 2% Topical Nail Liquid?

Store Fluconazole 2% Topical Nail Liquid at room temperature away from direct sunlight and heat. Keep the bottle tightly closed when not in use to prevent evaporation and contamination. Keep out of reach of children and pets to ensure safety.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.