Fluconazole 100 mg/g Topical Cream is a custom-compounded antifungal preparation designed for the treatment of various cutaneous fungal infections. Dispensed as a semisolid cream in a pump mechanism, it allows for convenient and controlled application directly to the skin, ensuring localized treatment and optimal absorption of the active ingredient.

Fluconazole belongs to the triazole class of antifungal agents and works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to increased cellular permeability and ultimately causes the death of the fungal cells. The high concentration of fluconazole in this formulation makes it particularly effective against a wide range of fungal pathogens, including species of Candida, dermatophytes, and certain molds.

This topical cream is especially beneficial for patients who require targeted antifungal therapy on the skin. By delivering a potent dose of fluconazole directly to the affected area, it can effectively treat conditions such as cutaneous candidiasis, tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot), and other superficial fungal infections. The use of a pump mechanism not only provides ease of application but also ensures precise dosing, reducing waste and enhancing treatment adherence.

For patients, this formulation offers the advantage of minimizing systemic exposure, thereby reducing the risk of systemic side effects often associated with oral antifungal medications. It is important to apply the cream exactly as prescribed by your healthcare provider, typically to clean, dry skin once or twice daily. Treatment duration may vary depending on the severity and type of infection but should be continued for the full course to prevent recurrence.

Patients should inform their healthcare provider of any known allergies to fluconazole or other azole antifungals. While topical fluconazole is generally well-tolerated, some individuals may experience mild local reactions such as redness, itching, or irritation at the application site. If these symptoms persist or worsen, or if you experience signs of an allergic reaction, discontinue use and seek medical attention promptly.

For prescribers, Fluconazole 100 mg/g Topical Cream provides a valuable option for treating resistant or severe fungal infections where conventional therapies may be inadequate. The high concentration allows for enhanced antifungal activity at the site of infection, which can be crucial in cases where systemic treatment is contraindicated or poses significant risks. When considering this formulation, evaluate the patient's overall medical condition, potential drug interactions, and the specific fungal pathogen involved.

If you have any questions or need further information about Fluconazole 100 mg/g Topical Cream, please reach out to us. Our team of experienced compounding pharmacists at Bayview Pharmacy is dedicated to supporting both patients and healthcare providers with personalized medication solutions and expert guidance.

Fluconazole 100 mg/g topical cream is a potent antifungal agent used primarily for the treatment of localized fungal infections on the skin. While topical application generally results in lower systemic absorption compared to oral administration, it is still important to consider potential drug interactions, especially in patients who may be using other medications concurrently. This is particularly relevant for patients with compromised skin barriers, which may increase systemic absorption.

Fluconazole is a known inhibitor of the cytochrome P450 enzyme system, particularly CYP2C9, CYP2C19, and CYP3A4. Although the systemic absorption from topical application is minimal, caution is advised when the cream is used in conjunction with medications metabolized by these enzymes. For instance, patients using warfarin, a CYP2C9 substrate, should be monitored for increased anticoagulant effects, as fluconazole can potentially enhance the effects of warfarin, leading to an increased risk of bleeding.

Additionally, patients using oral hypoglycemic agents such as sulfonylureas, which are also metabolized by CYP2C9, should be monitored for signs of hypoglycemia. The interaction between fluconazole and these agents could potentiate their effects, necessitating dosage adjustments. Similarly, caution should be exercised when co-administering with phenytoin, a CYP2C19 substrate, as fluconazole may increase phenytoin levels, potentially leading to toxicity.

For patients on statins, particularly those metabolized by CYP3A4 such as atorvastatin, there is a potential risk of increased statin levels, which could lead to adverse effects such as myopathy or rhabdomyolysis. It is advisable to monitor for muscle pain or weakness and consider adjusting the statin dose if necessary.

While the risk of systemic interactions is lower with topical application, it is important for prescribers to consider the overall medication profile of the patient, especially in those with extensive skin conditions or those using other topical or systemic medications. Patients should be advised to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to ensure safe and effective use of fluconazole topical cream.

If you have any questions or need further information regarding potential drug interactions with fluconazole 100 mg/g topical cream, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any concerns you may have.

Fluconazole 100 mg/g topical cream is a semisolid preparation specifically formulated for the treatment of fungal infections on the skin. This formulation is dispensed in a pump mechanism, which allows for convenient and controlled application, ensuring that the correct amount of medication is delivered to the affected area. The pump mechanism also helps maintain the stability and integrity of the cream by minimizing exposure to air and contaminants, which is crucial for maintaining the efficacy of the active ingredient, fluconazole.

Fluconazole is an antifungal agent that belongs to the class of medications known as triazole antifungals. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. By disrupting the production of ergosterol, fluconazole compromises the integrity of the fungal cell membrane, leading to increased permeability and ultimately causing the death of the fungal cells. This mechanism of action makes fluconazole effective against a wide range of fungal pathogens, including those responsible for conditions such as athlete's foot, jock itch, ringworm, and other dermatophyte infections.

The topical application of fluconazole allows for direct delivery of the active ingredient to the site of infection, which can enhance its effectiveness and reduce the risk of systemic side effects that may occur with oral antifungal treatments. The 100 mg/g concentration ensures a potent dose is available to combat the fungal infection, while the cream base facilitates absorption into the skin, allowing the medication to reach the deeper layers where the fungi may reside. This localized treatment approach is particularly beneficial for patients who may have contraindications to systemic antifungal therapy or who prefer a topical treatment option.

For prescribers, the fluconazole 100 mg/g topical cream offers a targeted treatment option that can be tailored to the specific needs of the patient. The controlled application provided by the pump mechanism ensures that patients can easily adhere to the prescribed treatment regimen, applying the cream as directed to achieve optimal therapeutic outcomes. Additionally, the formulation's design minimizes the risk of over-application or wastage, making it a cost-effective choice for both patients and healthcare providers.

Patients using this formulation should follow the application instructions provided by their healthcare provider, typically involving the application of a thin layer of cream to the affected area once or twice daily, depending on the severity of the infection and the prescriber's recommendations. It is important to continue using the cream for the full duration of the prescribed treatment period, even if symptoms improve, to ensure complete eradication of the fungal infection and prevent recurrence.

If you have any questions about fluconazole 100 mg/g topical cream or its use in treating fungal infections, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation.

Fluconazole 100 mg/g topical cream, dispensed in a semisolid preparation with a pump mechanism, is primarily used for the treatment of fungal infections on the skin. However, this formulation may have other potential uses that could be beneficial for both patients and prescribers seeking alternative therapeutic options. One such use is the management of seborrheic dermatitis, a common skin condition that causes scaly patches and red skin, primarily on the scalp. Fluconazole's antifungal properties can help reduce the yeast population on the skin, which is often implicated in seborrheic dermatitis, thereby alleviating symptoms and improving skin appearance.

Additionally, this formulation may be considered for use in the treatment of tinea versicolor, a condition characterized by small, discolored patches on the skin caused by an overgrowth of yeast. The topical application of fluconazole can help restore the normal balance of yeast on the skin, reducing the appearance of these patches. Furthermore, fluconazole cream may be used off-label for the treatment of certain cases of intertrigo, a rash that occurs in skin folds, where fungal overgrowth is suspected to be a contributing factor. By applying the cream directly to the affected areas, patients may experience relief from irritation and inflammation.

For prescribers, it is important to consider the patient's overall health status, potential drug interactions, and the specific characteristics of the skin condition when recommending fluconazole topical cream for these alternative uses. Patients should be advised on the proper application technique to ensure optimal absorption and effectiveness of the medication. As with any off-label use, it is crucial to monitor the patient's response to treatment and adjust the therapy as needed. If you have any questions or require further information about the potential uses of fluconazole 100 mg/g topical cream, please reach out to us at Bayview Pharmacy. We are here to assist you with any inquiries or concerns you may have regarding this formulation.