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Formulas

Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/ml Topical Cream

Bayview Pharmacy's compounded Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/ml Topical Cream is a semisolid preparation dispensed in a pump mechanism. This formulation is designed for convenient and controlled application on the skin, providing localized treatment or absorption of active ingredients. It is used to manage conditions such as Vulvovaginal Atrophy, Menopausal Symptoms, Postmenopausal Osteoporosis, Urogenital Atrophy, and Dyspareunia.

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Topical Cream
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Formula Information

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This topical cream is a compounded formulation of estriol, estradiol, and estrone, presented in an 80%-10%-10% ratio, with a concentration range of 0.625-2.5 mg/ml. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is primarily used for localized treatment or absorption of active ingredients.

The cream is primarily used to alleviate a variety of conditions, including menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It is also effective in treating vaginal atrophy, a condition that arises due to a decrease in estrogen levels, leading to discomfort during intercourse and an increased risk of infection.

Additionally, this formulation can be used for hormone replacement therapy, which is beneficial in treating a variety of conditions, including osteoporosis, hypogonadism, and endometriosis. Hormone replacement therapy helps to restore the body's natural hormone levels, thereby alleviating the symptoms associated with these conditions.

It is crucial to use this formulation as directed by your healthcare provider to ensure its safety and effectiveness. If you have any questions or concerns regarding the use of this product, please do not hesitate to reach out to us at Bayview Pharmacy. We are committed to providing you with the highest quality of care and service.

Drug Interactions

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This topical cream is a compounded formulation of estriol, estradiol, and estrone, presented in a ratio of 80%-10%-10%. The available strengths are 0.625-2.5 mg/ml. This hormone combination is typically used to manage a range of conditions such as menopausal symptoms, vaginal atrophy, and hypoestrogenism. It may also be prescribed for the treatment of osteoporosis, breast cancer, and endometriosis.

Patients should be aware that this medication may cause side effects including nausea, headache, breast tenderness, and vaginal bleeding. It may also increase the risk of serious health conditions such as blood clots, stroke, and heart attack. It is crucial that patients inform their healthcare provider if they have any of these conditions before starting this medication.

It's also important to note that this medication may interact with other medications. These include anticoagulants, anti-seizure medications, and certain antibiotics. Patients should inform their healthcare provider of any other medications they are currently taking before starting this medication.

This medication should not be used during pregnancy or breastfeeding. It may cause dizziness or drowsiness, and patients should avoid driving or operating machinery until they understand how this medication affects them. If you have any questions about this formulation or its potential interactions with other medications, please reach out to your healthcare provider.

How Does it Work

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This topical cream is a compounded formulation of estriol, estradiol, and estrone, presented in a ratio of 80%-10%-10%. The cream is available in strengths of 0.625-2.5 mg/ml. The combination of these estrogens, with estriol being a weak estrogen, estradiol a stronger one, and estrone the weakest, provides a balanced approach to hormone replacement therapy.

The cream is designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. It is used to treat a variety of conditions, including menopausal symptoms such as hot flashes and vaginal dryness. It can also be used in the treatment of osteoporosis, endometriosis, and uterine fibroids, and may reduce the risk of developing certain types of cancer.

When using this cream, it is crucial to follow the instructions provided by your healthcare provider. The cream should be applied to the affected area once or twice daily, depending on the strength prescribed. It is important to use the cream as directed, as using too much or too little can lead to side effects.

Common side effects of this topical cream include skin irritation, itching, and redness. If these side effects occur, it is important to contact your healthcare provider. Additionally, it is important to be aware of any potential interactions with other medications or supplements you may be taking.

If you have any questions about this topical cream, please do not hesitate to reach out. We are a team of compounding pharmacists at Bayview Pharmacy and are here to help.

Other Uses

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This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/ml is a topical cream designed for localized treatment or absorption of active ingredients. It is dispensed in a pump mechanism for convenient and controlled application on the skin. This formulation may be used to treat a variety of conditions including hypoestrogenism, endometriosis, and premenstrual syndrome. It may also be beneficial in reducing the risk of breast cancer and endometrial hyperplasia in postmenopausal women with an intact uterus.

Furthermore, this formulation may be used to address symptoms of androgen deficiency in women, such as hirsutism, acne, and alopecia. It may also be beneficial for women experiencing symptoms of androgen excess, such as polycystic ovarian syndrome. This formulation may also be used to alleviate symptoms of premature ovarian failure, such as hot flashes, night sweats, and vaginal dryness.

Additionally, this formulation may be used to treat symptoms of Turner Syndrome, such as delayed puberty and short stature. If you have any questions about the use of this formulation for any of these conditions, please reach out for further information.

Frequently Asked Questions

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What is the Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/ml Topical Cream?

This is a compounded formulation of three types of estrogen hormones: Estriol, Estradiol, and Estrone. It is a semisolid preparation designed for application on the skin. The cream is dispensed in a pump mechanism for convenient and controlled application.

What is the purpose of this cream?

The cream is designed for localized treatment or absorption of active ingredients. It is typically used in hormone replacement therapy for menopausal symptoms or other conditions related to estrogen deficiency.

How should I apply this cream?

The cream should be applied to the skin as directed by your healthcare provider. The pump mechanism allows for controlled application of the cream.

What is the concentration of the hormones in this cream?

The cream contains Estriol, Estradiol, and Estrone in the ratio of 80%, 10%, and 10% respectively. The concentration of the hormones is 0.625-2.5 mg/ml.

What are the potential side effects of this cream?

As with any medication, side effects can occur. These may include skin irritation at the application site, changes in menstrual periods, mood changes, weight gain, or breast tenderness. Always consult your healthcare provider if you experience any unusual symptoms.

Can I use this cream if I am pregnant or breastfeeding?

Estrogen creams are generally not recommended for use during pregnancy or while breastfeeding. Always consult your healthcare provider before starting any new medication.

How should I store this cream?

Store the cream at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not apply two doses at the same time.

Can I use other skincare products while using this cream?

Yes, you can use other skincare products while using this cream. However, it is recommended to apply the cream first and allow it to absorb into the skin before applying other products.

What should I do in case of an overdose?

If you suspect an overdose, contact a healthcare provider immediately. Symptoms of an overdose may include severe nausea, vomiting, or heavy bleeding.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.