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Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg Troche

This troche combines estriol, estradiol, and estrone in an 80%-10%-10% ratio, with a dosage range of 0.625-2.5 mg. It is designed to dissolve slowly in the mouth, allowing for oral mucosa absorption. The medication is used for the treatment of menopausal symptoms, osteoporosis, uterine prolapse, vaginal atrophy, and dyspareunia.

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Estriol
Estradiol
Estrone
Troches
6427079ea6432471f1518aca
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Formula Information

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This troche formulation is a compounded blend of estriol, estradiol, and estrone, presented in an 80%-10%-10% ratio. The dosage range for this medication is between 0.625-2.5 mg. The unique combination of these hormones makes this formulation an effective treatment for a variety of conditions, including menopausal symptoms, postmenopausal osteoporosis, and hormone replacement therapy.

Estriol, which constitutes 80% of the formulation, is a weak estrogen that is known to alleviate symptoms such as hot flashes and night sweats. Estradiol, making up 10% of the formulation, is a stronger estrogen that aids in reducing vaginal dryness and improving bone density. The remaining 10% is estrone, a weaker estrogen that helps to reduce the risk of endometrial hyperplasia.

The troche is a square-shaped solid dosage form designed to dissolve slowly in the mouth. The medication is delivered through absorption by the oral mucosa, allowing for targeted local or systemic effects. This method of delivery ensures a steady release of the hormones into the body, providing relief from symptoms over a sustained period.

It is crucial to note that this formulation should not be used by women who are pregnant or breastfeeding. As with any medication, it is important to discuss potential risks and benefits with your healthcare provider before starting this treatment. Regular monitoring and dosage adjustments may be necessary to ensure the medication is working effectively and safely.

If you have any questions about this troche formulation or how it can help manage your condition, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is equipped with the knowledge and expertise to assist you in understanding your medication and its effects.

Drug Interactions

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This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg Troche is a specialized medication used to manage a variety of conditions. It is particularly effective in treating menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. The Estriol component, a weak estrogen, is primarily responsible for alleviating these symptoms.

The Estradiol and Estrone components, stronger and weaker estrogens respectively, contribute to the reduction of osteoporosis risk. These components also aid in managing menopausal symptoms. Furthermore, this formulation is utilized in hormone replacement therapy, a treatment approach used to supplement hormones that the body is no longer producing.

It is crucial to be aware that this formulation may interact with other medications. These include anticoagulants, anticonvulsants, and certain antibiotics. Additionally, this formulation may increase the risk of certain side effects, such as nausea, vomiting, and headaches. More serious risks include an increased likelihood of developing conditions such as breast cancer, stroke, and blood clots.

Given these potential interactions and side effects, it is essential to have a comprehensive discussion with your healthcare provider before starting this medication. This will ensure that the benefits of the medication outweigh any potential risks. If you have any questions or concerns, do not hesitate to reach out to your healthcare provider for further information and guidance.

How Does it Work

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This troche formulation is a compounded blend of estriol, estradiol, and estrone, in a ratio of 80%-10%-10%, available in doses ranging from 0.625 to 2.5 mg. It is primarily used in the treatment of menopausal symptoms, postmenopausal osteoporosis, and as part of hormone replacement therapy. The estriol component, a mild estrogen, aids in alleviating symptoms such as hot flashes, night sweats, and vaginal dryness. Estradiol, a more potent estrogen, contributes to the reduction of osteoporosis risk and also helps in managing hot flashes and night sweats. Estrone, another form of estrogen, albeit weaker, also assists in reducing osteoporosis risk and managing menopausal symptoms.

The troche is designed to be taken orally, typically once a day, and it is recommended to take it at the same time each day to maintain consistent hormone levels in the body. To minimize the risk of stomach upset, it is advisable to take the troche with food. The troche should be stored at room temperature, away from moisture and heat, to maintain its efficacy.

Before starting this medication, it is crucial to discuss potential side effects with your healthcare provider. Common side effects may include nausea, vomiting, headache, breast tenderness, and vaginal bleeding. It is also important to discuss any potential drug interactions with your healthcare provider before starting this medication.

If you have any questions about this troche formulation or its mechanism of action, please do not hesitate to reach out. Our team of compounding pharmacists at Bayview Pharmacy is here to assist you.

Other Uses

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This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg Troche is a square-shaped solid dosage form designed to dissolve slowly in the mouth. The medication is delivered through oral mucosa absorption for targeted local or systemic effects. It is used to treat a variety of conditions including hypoestrogenism, endometriosis, premenstrual syndrome, and postmenopausal bleeding. It may also be used to reduce the risk of developing breast cancer in women who are at high risk for the disease.

Additionally, this formulation may be used to treat symptoms of prostate cancer in men, such as hot flashes, night sweats, and decreased libido. It may also be used to treat symptoms of benign prostatic hyperplasia (BPH) in men, such as difficulty urinating, frequent urination, and weak urine stream. This formulation may also be used to treat symptoms of androgen deficiency in men, such as decreased libido, fatigue, and depression.

It is important to note that this formulation should not be used to treat any condition in children or adolescents. Additionally, this formulation should not be used to treat any condition in pregnant or breastfeeding women. If you have any questions about the uses of this formulation, please reach out to us.

Frequently Asked Questions

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What is the Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg Troche?

This is a compounded formulation of three types of estrogen hormones: Estriol, Estradiol, and Estrone. The formulation is designed in a square-shaped solid dosage form that dissolves slowly in the mouth, delivering medication through oral mucosa absorption for targeted local or systemic effects.

How does the Estriol/Estradiol/Estrone Troche work?

The troche works by slowly dissolving in the mouth and delivering the medication through the oral mucosa. This allows for the medication to be absorbed directly into the bloodstream, providing targeted local or systemic effects.

What is the purpose of the different percentages in the formulation?

The percentages represent the proportion of each type of estrogen in the formulation. In this case, 80% is Estriol, 10% is Estradiol, and 10% is Estrone. This specific ratio is designed to provide the most effective treatment for the patient.

How should I take the Estriol/Estradiol/Estrone Troche?

The troche should be placed in the mouth and allowed to dissolve slowly. It should not be chewed or swallowed whole. The medication is absorbed through the oral mucosa, so it's important to let it dissolve completely for maximum effectiveness.

What are the potential side effects of this medication?

As with any medication, there can be potential side effects. These can include nausea, bloating, breast tenderness, and headache. If you experience any severe or persistent side effects, you should contact your healthcare provider immediately.

Can I take this medication if I am pregnant or breastfeeding?

It's important to discuss any medications with your healthcare provider if you are pregnant or breastfeeding. Estrogen hormones can have effects on pregnancy and breastfeeding, so it's crucial to have this conversation with your healthcare provider.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Can I drink alcohol while taking this medication?

It's always best to discuss this with your healthcare provider. Alcohol can potentially interfere with the absorption and effectiveness of the medication.

How should I store the Estriol/Estradiol/Estrone Troche?

The troche should be stored at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can I take this medication with other prescriptions?

Before starting any new medication, you should always discuss it with your healthcare provider. They can provide guidance on potential interactions between medications.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.