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Formulas

Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel

Bayview Pharmacy's Estriol/Estradiol Topical Gel is a compounded formulation with a 50/50 ratio of estriol and estradiol, at a concentration of 0.25-2.5 mg/gm. This semisolid formulation is dispensed through a pump mechanism, allowing for easy and precise application on the skin. It is designed for targeted treatment or absorption of active ingredients, offering a gel-like consistency. The gel is used for the treatment of conditions such as vulvovaginal atrophy, lichen sclerosus, lichen planus, genitourinary syndrome of menopause, and postmenopausal vaginal dryness.

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Topical Gel
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Formula Information

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Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel is a specially compounded medication designed to treat a variety of health conditions. This unique formulation combines estriol and estradiol, two hormones naturally produced by the body, in a gel-like consistency that is easily applied to the skin. The gel is dispensed through a pump mechanism, which allows for precise application and targeted treatment.

The range of doses available, from 0.25 to 2.5 mg/gm, makes this medication versatile and adaptable to the specific needs of the patient. It is primarily used to alleviate menopausal symptoms, such as hot flashes and night sweats, as well as to treat vaginal dryness and vulvovaginal atrophy. Additionally, it can be beneficial for skin conditions like eczema, psoriasis, and dermatitis. This formulation can also be used to address symptoms of androgen deficiency, such as low libido and fatigue.

It is crucial to use this medication as directed by your healthcare provider to ensure its safety and effectiveness. Pregnant or breastfeeding women should not use this medication due to potential risks. As with any medication, it is important to discuss any potential side effects or interactions with your healthcare provider.

At Bayview Pharmacy, our team of compounding pharmacists is dedicated to creating customized medications to meet the unique needs of our patients. We are experienced in compounding a wide range of medications, including Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel. If you have any questions about this medication or any other compounded medications, we are here to help.

Drug Interactions

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This compounded formulation of Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel is a semisolid preparation designed for easy and precise application on the skin. It is primarily used for the treatment of menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It may also be beneficial for women suffering from vulvovaginal atrophy, a condition that arises due to decreased estrogen levels in postmenopausal women. Furthermore, this formulation can be used to treat hypoestrogenism, a condition characterized by low levels of estrogen in premenopausal women.

Studies have shown that this formulation can effectively reduce the frequency and severity of hot flashes, night sweats, and vaginal dryness. It may also enhance vaginal lubrication and decrease the risk of urinary tract infections. Additionally, this formulation may help to reduce the risk of osteoporosis and improve overall quality of life.

Patients should be aware that this formulation may cause skin irritation, itching, or burning at the application site. If these side effects occur, patients should contact their healthcare provider. It is also important to note that this formulation may increase the risk of breast cancer, endometrial cancer, and stroke. Patients should discuss these risks with their healthcare provider before starting treatment.

This formulation should not be used by pregnant or breastfeeding women. Additionally, it should not be used by patients with a history of breast cancer, endometrial cancer, or stroke. If you have any questions about this formulation or how it may interact with other medications, please consult with your healthcare provider.

How Does it Work

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This topical gel is a compounded formulation of Estriol and Estradiol, both of which are hormones naturally produced by the body. The gel is available in strengths of 0.25-2.5 mg/gm and is designed for direct application to the skin. It is primarily used to alleviate a range of conditions including menopausal symptoms such as hot flashes and vaginal dryness, as well as certain skin conditions like acne, eczema, and psoriasis.

When applied to the skin, the Estriol and Estradiol in the gel are absorbed into the bloodstream. These hormones can help to reduce symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness. Additionally, they can contribute to the reduction of wrinkles and improvement of skin elasticity.

The gel is dispensed through a pump mechanism, which facilitates easy and precise application. Depending on the severity of the condition being treated, it should be applied to the affected area once or twice daily. It is crucial to follow the instructions provided by your healthcare provider when using this product. Avoid contact with the eyes, mouth, and other mucous membranes to prevent any potential irritation or adverse effects.

If you have any questions or concerns about using this formulation, please do not hesitate to reach out. Our team of compounding pharmacists at Bayview Pharmacy is here to assist you. We are committed to providing you with the most accurate and up-to-date information to ensure your treatment is effective and safe.

Other Uses

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This compounded formulation of Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel is a versatile treatment option for a variety of conditions. It is primarily used for the relief of symptoms associated with menopause such as vaginal dryness, itching, burning, and irritation. The gel-like consistency allows for easy and precise application on the skin, ensuring targeted treatment and absorption of the active ingredients.

Furthermore, this formulation may also be used to reduce the risk of recurrent urinary tract infections in postmenopausal women. The estrogen in the formulation can help maintain the health of the urinary tract, reducing the likelihood of infections.

Additionally, this formulation may be beneficial in reducing the risk of recurrent bacterial vaginosis in postmenopausal women. Bacterial vaginosis is a common condition caused by an imbalance of bacteria in the vagina, and this formulation can help restore this balance.

Moreover, this formulation may also be used to reduce the risk of recurrent vulvovaginal candidiasis in postmenopausal women. Vulvovaginal candidiasis, also known as yeast infection, is caused by an overgrowth of a fungus called Candida. The estrogen in this formulation can help maintain the health of the vaginal environment, reducing the likelihood of yeast overgrowth.

It is important to note that the use of this formulation should be under the guidance of a healthcare professional. If you have any questions about the use of this formulation, please consult with your healthcare provider.

Frequently Asked Questions

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What is the Estriol/Estradiol [50%/50%] 0.25-2.5 mg/Gm Topical Gel?

This is a semisolid formulation of Estriol and Estradiol, two forms of estrogen, in equal proportions. It is dispensed through a pump mechanism for easy and precise application on the skin. The active ingredients are absorbed through the skin for targeted treatment.

How does the pump mechanism work?

The pump mechanism allows for easy and precise dispensing of the gel. It ensures that the right amount of medication is applied each time, reducing the risk of overdose or underdose.

How should I apply the Estriol/Estradiol Topical Gel?

You should apply the gel to clean, dry skin as directed by your healthcare provider. The gel should be rubbed in gently until it is fully absorbed.

What is the consistency of the Estriol/Estradiol Topical Gel?

The gel has a semisolid, gel-like consistency. This makes it easy to apply and allows for quick absorption of the active ingredients into the skin.

What are the active ingredients in the Estriol/Estradiol Topical Gel?

The active ingredients in the gel are Estriol and Estradiol, two forms of estrogen. They are present in equal proportions in the gel.

What is the purpose of the Estriol/Estradiol Topical Gel?

The gel is used for targeted treatment of conditions that respond to estrogen therapy. The active ingredients are absorbed through the skin, providing a direct route of administration.

Can I use the Estriol/Estradiol Topical Gel if I am pregnant or breastfeeding?

You should not use the gel if you are pregnant or breastfeeding without consulting your healthcare provider. Estrogen can have effects on pregnancy and breastfeeding, so it is important to discuss this with your healthcare provider.

What should I do if I miss a dose of the Estriol/Estradiol Topical Gel?

If you miss a dose of the gel, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

What are the potential side effects of the Estriol/Estradiol Topical Gel?

Side effects can include skin irritation at the application site, changes in menstrual periods, mood changes, weight changes, and others. If you experience any unusual symptoms, contact your healthcare provider.

How should I store the Estriol/Estradiol Topical Gel?

The gel should be stored at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.