This topical cream is a compounded formulation of estriol/estradiol [50%/50%] and progesterone, with concentrations ranging from 0.1-2.5 mg/gm and 10-100 mg/gm, respectively. This unique blend of hormones is designed to address a variety of health conditions, including menopausal symptoms, endometriosis, and uterine fibroids. It is also an effective treatment for vulvovaginal atrophy, a condition that can cause discomfort due to dryness, itching, and burning in the vagina.

The combination of estriol/estradiol and progesterone in this formulation works synergistically to alleviate these conditions. Estriol/estradiol, a form of estrogen, helps to mitigate menopausal symptoms by replenishing the body's estrogen levels, which naturally decrease during menopause. Progesterone, on the other hand, is known to help reduce the symptoms of endometriosis and uterine fibroids by counteracting the effects of estrogen on the uterine lining. Together, these hormones provide relief from the symptoms associated with vulvovaginal atrophy by restoring hormonal balance and promoting vaginal health.

This semisolid preparation is dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of the active ingredients, ensuring optimal effectiveness. It is crucial to use this product as directed by your healthcare provider to ensure safety and efficacy. If you have any questions or concerns about this formulation or its use, please do not hesitate to contact your healthcare provider or pharmacist.

This compounded formulation of Estriol/Estradiol [50%/50%] 0.1-2.5 mg/Gm and Progesterone 10-100 mg/Gm is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for the localized treatment of menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It can also be used to treat vulvar and vaginal atrophy, and to reduce the risk of endometrial hyperplasia in postmenopausal women.

Additionally, this formulation may be used to treat symptoms of hypoestrogenism, such as osteoporosis, and to reduce the risk of breast cancer in postmenopausal women. However, it should not be used to prevent heart disease or dementia. It is crucial to discuss any potential risks and benefits with a healthcare provider before starting treatment.

Patients should be aware that this formulation may cause side effects, such as nausea, headache, breast tenderness, and vaginal bleeding. It may also interact with other medications, such as anticoagulants, insulin, and certain antibiotics. Therefore, it is important to inform the healthcare provider of all medications being taken before starting treatment.

Prescribers should be aware that this formulation should not be used in patients with a history of thromboembolic disorders, undiagnosed abnormal genital bleeding, or known or suspected estrogen-dependent neoplasia. It should also not be used in patients with a history of liver disease or liver dysfunction. Regular monitoring for signs and symptoms of thromboembolic disorders, such as chest pain, shortness of breath, and leg swelling, is recommended.

If you have any questions about this formulation or its use, please consult with your healthcare provider. It is important to use this medication as directed by your healthcare provider to ensure the best possible outcome.

This compounded formulation is a topical cream that combines estriol and estradiol in a 50/50 ratio, with concentrations of 0.1-2.5 mg/gm, and progesterone at 10-100 mg/gm. It is designed to treat a range of conditions including menopausal symptoms, endometriosis, and uterine fibroids.

When applied to the skin, the estriol and estradiol components are absorbed into the bloodstream, where they bind to estrogen receptors in the body. This interaction helps alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. The progesterone component of the cream aids in reducing the risk of endometrial hyperplasia, a condition characterized by an excessively thick uterine lining. It also helps alleviate symptoms of endometriosis, such as pelvic pain and heavy menstrual bleeding, and contributes to the reduction of uterine fibroid size, which can cause pain and heavy menstrual bleeding.

The cream is designed for convenient and controlled application on the skin. It should be applied to the affected area once or twice daily, or as directed by your healthcare provider. The amount of cream used and the frequency of application may vary depending on individual needs. It is crucial to avoid getting the cream in the eyes, nose, or mouth.

If you have any questions about this formulation or its application, please do not hesitate to reach out. We are a team of compounding pharmacists at Bayview Pharmacy, and we are here to assist you.

This compounded formulation of Estriol/Estradiol [50%/50%] 0.1-2.5 mg/Gm/Progesterone 10-100 mg/Gm is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for localized treatment or absorption of active ingredients. This topical cream has been found effective in treating a variety of conditions including acne, hirsutism, and polycystic ovarian syndrome. It is also beneficial in reducing the risk of endometrial hyperplasia in postmenopausal women undergoing estrogen therapy.

Furthermore, this formulation has been utilized to alleviate symptoms of premenstrual syndrome such as mood swings, irritability, and breast tenderness. It also plays a significant role in reducing the risk of osteoporosis in postmenopausal women. In addition, this formulation has been used to address symptoms of androgen deficiency in women, including low libido, fatigue, and depression. If you have any questions about the use of this formulation for any of these conditions, please do not hesitate to reach out for further information.