Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel

This topical gel is a compounded formulation of Estriol/Estradiol [50%/50%] and Testosterone, with concentrations ranging from 0.05-0.5 mg/gm and 0.25-10 mg/gm respectively. It is dispensed through a pump mechanism for easy and precise application. The gel is used for targeted treatment of conditions such as vulvovaginal atrophy, menopause, hypoestrogenism, postmenopausal osteoporosis, and urogenital syndrome.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Estriol
Estradiol
Testosterone
Topical Gel
6427079ea643246235518acd
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This topical gel formulation is a compounded blend of estriol/estradiol [50%/50%] and testosterone, with concentrations ranging from 0.05-0.5 mg/gm for estriol/estradiol and 0.25-10 mg/gm for testosterone. This unique formulation is designed to address a variety of health conditions, including menopausal symptoms, hypoactive sexual desire disorder, and postmenopausal osteoporosis.

Estriol and estradiol are two forms of estrogen, a hormone naturally produced by the body. Estriol is a milder form of estrogen, while estradiol is more potent. When combined, these two hormones can effectively alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Additionally, they can enhance sexual desire and decrease the risk of postmenopausal osteoporosis.

Testosterone, another hormone naturally produced by the body, is also included in this formulation. Testosterone plays a crucial role in maintaining sexual desire and libido, as well as muscle strength and bone density. In this formulation, testosterone works synergistically with estriol and estradiol to further alleviate menopausal symptoms and enhance sexual desire.

This topical gel formulation is dispensed through a pump mechanism, facilitating easy and precise application on the skin for targeted treatment. The gel-like consistency allows for optimal absorption of the active ingredients, making it an effective treatment option for menopausal symptoms, hypoactive sexual desire disorder, and postmenopausal osteoporosis. If you have any questions or concerns about this formulation, please do not hesitate to contact us.

Drug Interactions

A small arrow pointing down

Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel is a compounded formulation designed for targeted treatment of various conditions. It is primarily used for the management of menopausal symptoms, including hot flashes, night sweats, and vaginal dryness. Additionally, it is indicated for the treatment of hypoactive sexual desire disorder (HSDD) in postmenopausal women.

This formulation also serves as a therapeutic option for men suffering from androgen deficiency, which can manifest as low libido, fatigue, and depression. The gel should be applied to the skin once daily, preferably in the morning, ensuring that the lowest effective dose is used to minimize the risk of adverse reactions.

Patients are advised to avoid contact with the eyes, mouth, and other mucous membranes during application. It is also recommended to avoid sun exposure and to use sunscreen when outdoors to protect the treated area. Regular monitoring for signs of hyperandrogenism, such as hirsutism, acne, and alopecia, is crucial. If any of these signs are present, the dose should be adjusted or the medication should be discontinued.

It is important to note that this is a specialized formulation and should be used under the guidance of a healthcare professional. If you have any questions or concerns regarding this medication, please consult with your healthcare provider.

How Does it Work

A small arrow pointing down

Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel is a specially compounded formulation designed to deliver a precise balance of hormones directly through the skin. This topical gel combines estriol and estradiol, hormones that are naturally produced by the body and play crucial roles in maintaining healthy bones, skin, and reproductive organs. Additionally, it contains testosterone, a hormone vital for maintaining muscle mass, libido, and energy levels.

This unique combination of hormones is designed to restore hormonal balance in the body and can be used to treat a variety of conditions. It is commonly used to alleviate menopausal symptoms, such as hot flashes and vaginal dryness, and to boost libido. It can also be beneficial in treating conditions like osteoporosis, andropause, and hypogonadism, where there is a deficiency or imbalance of these hormones.

The gel is applied directly to the skin, where it is absorbed into the bloodstream. This method of application allows for targeted treatment, with the active ingredients being released into the body to restore balance. The dosage of Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel will vary depending on the condition being treated and the individual needs of the patient. It is crucial to follow the instructions of your healthcare provider when using this medication and not to exceed the recommended dosage.

If you have any questions about Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel or how it can help treat your condition, please consult with your healthcare provider. They can provide you with the most accurate and personalized advice based on your specific needs and medical history.

Other Uses

A small arrow pointing down

This compounded formulation of Estriol/Estradiol [50%/50%] 0.05-0.5 mg/Gm/Testosterone 0.25-10 mg/Gm Topical Gel is a semisolid formulation dispensed through a pump mechanism. It is designed for easy and precise application on the skin, allowing for targeted treatment or absorption of active ingredients in a gel-like consistency. This formulation may be used to treat a variety of conditions such as endometriosis, premenstrual syndrome, and polycystic ovarian syndrome.

Furthermore, it may also be used to reduce the risk of several health conditions in postmenopausal women. These include breast cancer, cardiovascular disease, endometrial hyperplasia, endometrial cancer, colorectal cancer, fractures, urinary incontinence, dementia, depression, stroke, Alzheimer's disease, Parkinson's disease, and osteoporosis. If you have any questions about the other uses of this formulation, please reach out to us.

Frequently Asked Questions

A small arrow pointing down

What is the Estriol/Estradiol/Testosterone Topical Gel?

This is a compounded formulation of Estriol, Estradiol, and Testosterone. It is a semisolid formulation dispensed through a pump mechanism, facilitating easy and precise application on the skin for targeted treatment or absorption of active ingredients in a gel-like consistency.

How does the pump mechanism work?

The pump mechanism allows for easy and precise application of the gel. It dispenses a measured amount of the gel, ensuring that you get the correct dosage each time.

How should I apply the Estriol/Estradiol/Testosterone Topical Gel?

You should apply the gel to clean, dry skin. The exact location and frequency of application will depend on your doctor's instructions. Always wash your hands thoroughly after applying the gel.

What are the active ingredients in this gel?

The active ingredients in this gel are Estriol, Estradiol, and Testosterone. The concentrations of these hormones can vary, but the typical formulation includes 50% Estriol, 50% Estradiol, and a variable amount of Testosterone.

What is the purpose of the Estriol and Estradiol in the gel?

Estriol and Estradiol are forms of estrogen, a hormone that plays a crucial role in women's health. They are often used in hormone replacement therapy to help alleviate symptoms of menopause, such as hot flashes and vaginal dryness.

What is the role of Testosterone in this gel?

Testosterone is a hormone that is important for both men and women. In women, it can help improve sexual desire, mood, and energy levels. In men, it can help with symptoms of low testosterone, such as fatigue and decreased libido.

Are there any side effects of using this gel?

As with any medication, there can be side effects. These may include skin irritation at the application site, changes in mood or libido, and others. If you experience any unusual or severe side effects, contact your doctor immediately.

Can I use this gel if I am pregnant or breastfeeding?

You should not use this gel if you are pregnant or breastfeeding, as the hormones in the gel can potentially harm the baby. Always consult your doctor before starting any new medication.

How should I store the Estriol/Estradiol/Testosterone Topical Gel?

Store the gel at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.