Our custom-compounded topical cream is a unique formulation that combines four bio-identical hormones: Estradiol, Estriol, Progesterone, and Testosterone. Each milliliter of this cream contains 0.1 mg of Estradiol, 0.8 mg of Estriol, 40 mg of Progesterone, and 1 mg of Testosterone. This carefully balanced hormone combination is designed to address various symptoms associated with hormonal imbalances or deficiencies that may occur during menopause, perimenopause, or as part of hormone replacement therapy (HRT).

Estradiol and Estriol are forms of estrogen, a hormone that plays a vital role in the female reproductive system and overall well-being. Estradiol is the most potent form of estrogen and can help alleviate symptoms such as hot flashes, vaginal dryness, and bone density loss. Estriol, being a weaker estrogen, offers a gentler option with fewer side effects, and is often used to improve vaginal tissue and urinary health. The combination of these two estrogens aims to provide a balanced approach to estrogen supplementation, potentially reducing the risks associated with estrogen therapy.

Progesterone is included in this formulation to counterbalance the effects of estrogen and maintain a healthy endometrial lining, which can help prevent estrogen-dominant conditions. It is also known for its calming effects and can aid in improving sleep quality and mood. Testosterone, although typically considered a male hormone, plays a crucial role in female health as well. It can contribute to libido, energy levels, and muscle strength. The inclusion of testosterone in this formulation is intended to address symptoms such as low sex drive, fatigue, and muscle weakness.

The cream is dispensed in a pump mechanism, which allows for precise dosing and ease of application. The semisolid preparation is designed for topical use, where the hormones are absorbed through the skin directly into the bloodstream, bypassing the gastrointestinal tract and liver, which can minimize potential side effects and improve hormonal uptake. This route of administration can be particularly beneficial for individuals who may have difficulties with oral medications or for those who prefer localized treatment.

This hormone therapy cream may be prescribed for conditions such as menopausal symptoms, hormone deficiencies, and certain cases of osteoporosis, among others. It is important to note that hormone replacement therapy should be tailored to the individual's needs and regularly monitored by a healthcare provider. Our team at Bayview Pharmacy is committed to providing high-quality, customized medications to meet the specific needs of our patients. If you have any questions or require further information about this formulation and its suitability for treating specific disease states, please do not hesitate to reach out to us.

This topical cream formulation contains a combination of hormones: estradiol, estriol, progesterone, and testosterone. Each of these hormones can interact with various medications, and it is important to consider potential drug interactions when prescribing or using this formulation. Estradiol and estriol, both forms of estrogen, can interact with thyroid hormone replacement therapy, as estrogens may increase thyroid-binding globulin (TBG) levels, leading to decreased thyroid hormone efficacy. Patients on thyroid replacement therapy may require monitoring and possible dose adjustments. Additionally, estrogens can reduce the clearance of certain benzodiazepines and tricyclic antidepressants, potentially increasing their effects and risk of side effects.

Progesterone can interact with medications metabolized by cytochrome P450 enzymes, particularly CYP3A4. Drugs such as ketoconazole, itraconazole, and clarithromycin may inhibit the metabolism of progesterone, leading to increased levels and potential side effects. Conversely, inducers of CYP3A4, such as phenytoin, carbamazepine, and St. John's Wort, may decrease progesterone levels, reducing its efficacy. Progesterone may also interact with benzodiazepine receptor agonists, enhancing their sedative effects.

Testosterone can interact with oral anticoagulants, such as warfarin, by potentially altering the anticoagulant's effects, which may necessitate dose adjustments and close monitoring of coagulation parameters. Additionally, testosterone may affect blood glucose levels, and patients with diabetes should be monitored closely as insulin or oral hypoglycemic dosage may need to be adjusted.

It is also important to note that the use of this hormone combination can influence the metabolism of other medications by affecting liver enzyme activity. Patients should be advised to inform their healthcare providers of all medications, supplements, and herbal products they are taking to assess for potential interactions. This formulation is used to treat various conditions related to hormone deficiencies or imbalances, such as menopausal symptoms, androgen deficiency, and certain cases of premenstrual syndrome (PMS). The specific effects of the hormones in this formulation can provide relief from symptoms such as hot flashes, vaginal atrophy, mood swings, decreased libido, and other hormone-related issues.

Due to the complexity of hormone interactions, it is crucial for prescribers to evaluate each patient's medication profile for potential interactions and adjust therapy as needed. Patients should be monitored for signs of excess or inadequate hormone exposure, and doses should be individualized based on response and laboratory values. If you have any questions or require further information regarding this formulation and its interactions, please reach out to us at Bayview Pharmacy for assistance.

The formulation you've inquired about is a compounded topical cream containing a combination of hormones: estradiol, estriol, progesterone, and testosterone. Each of these hormones plays a unique role in the body, and their combination is often used to address various symptoms associated with hormonal imbalances or deficiencies, particularly in the context of menopause or andropause.

Estradiol, at 0.1 mg per mL, is a form of estrogen, a primary female sex hormone. It is responsible for the regulation of the menstrual cycle and is also important for maintaining the health of the reproductive tissues, bone density, and skin health. Estriol, at 0.8 mg per mL, is another form of estrogen that is weaker than estradiol but still plays a role in supporting menopausal symptoms and may have fewer side effects.

Progesterone, at 40 mg per mL, is a hormone that balances the effects of estrogen and is essential for regulating the menstrual cycle and maintaining the early stages of pregnancy. It also has a calming effect on the brain and can help with sleep and mood regulation.

Testosterone, at 1 mg per mL, although commonly known as a male hormone, is also present in females in smaller amounts. It contributes to libido, muscle mass, strength, and bone density. In both men and women, testosterone can help improve energy levels and overall sense of well-being.

This topical cream is designed to be applied to the skin, where the hormones are absorbed directly into the bloodstream, bypassing the gastrointestinal tract and liver, which can alter hormone levels and lead to side effects. The cream is dispensed in a pump mechanism that allows for controlled dosing, ensuring that patients receive the correct amount of medication with each application. This method of delivery can also localize treatment to specific areas, which may be beneficial for certain conditions.

The diseases and symptoms this formulation may treat include menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and mood swings. It may also be used to address andropause symptoms in men, such as decreased libido, fatigue, and loss of muscle mass. Additionally, this hormone combination can be used in hormone replacement therapy for individuals with hormonal deficiencies or imbalances.

It is important for patients and prescribers to understand that hormone therapy should be tailored to the individual's needs and regularly monitored for effectiveness and potential side effects. If you have any questions or require further information about this formulation and its use, please reach out to us at Bayview Pharmacy. We are here to provide guidance and support to ensure the safe and effective use of compounded hormone therapies.

The estradiol, estriol, progesterone, and testosterone topical cream formulation from Bayview Pharmacy is primarily prescribed to address hormone imbalances and associated symptoms such as those found in perimenopause, menopause, andropause, and as a part of hormone replacement therapy (HRT). Beyond its primary use, there may be other conditions and applications where this formulation could provide benefits, though these are generally off-label and should be considered carefully alongside the advice of a healthcare provider.

In some cases, this cream may be used to help improve skin elasticity and thickness, as some studies suggest that topical hormones can influence skin collagen content and reduce the appearance of fine lines and wrinkles. Additionally, there may be improvements in skin hydration and overall skin health due to the hormonal effects on skin physiology. It is also sometimes used to help manage sexual dysfunction or reduce symptoms such as decreased libido; the testosterone in the formulation can be particularly relevant for this use.

For patients with conditions like vulvodynia or lichen sclerosus where localized hormone therapy is indicated, the anti-inflammatory properties of progesterone and the estrogenic support for mucosal tissues can provide symptomatic relief. The careful balance of hormones in this topical formulation must, however, be closely monitored by healthcare professionals, as the systemic absorption of hormones through the skin has the potential to disturb the overall hormone balance within the body if not managed properly.

Considering the diverse effects of hormones on the body, this formulation might also be explored for potential improvement in bone density, particularly in individuals who are unable to take oral or systemic hormone treatments. Estrogen plays a key role in bone health, and some practitioners may investigate the use of such topical formulations in an osteoporosis management plan.

Another potential use of this compound may involve addressing hair loss or thinning that has a hormonal component, especially in cases related to lower levels of estrogen or testosterone. However, the evidence and guidelines supporting such uses are less clear, and individual responses can vary significantly. Therefore, this application should be undertaken with caution and professional guidance.

It is imperative that any consideration of the above uses for this customized hormone cream occur within the context of a comprehensive treatment plan developed in collaboration with a healthcare provider well-versed in hormone therapies. The formulation should be used precisely as directed, and any off-label uses should be approached with an understanding of both the potential benefits and risks.

Patients and prescribers who are interested in exploring the uses of this topical hormone cream or have questions regarding its application are encouraged to reach out to us at Bayview Pharmacy for further information and consultation. Our team of compounding pharmacists is dedicated to providing personalized care and guidance to ensure safe and effective use of all compounded medications.